Gene bon (Fruit Fly)
Sequence
Protein domains of bon.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| RING | bon.AA | RING | 83-130 | 22 | 7e-06 | 26.69 | SMART | 1-23 (23) | Show / Hide |
Range on Protein: 83-130 Range on HMM: 1-23/23 Sequence Identity: 22% (11 aa) CVYCAQLLGSNDRPKLLECLHVACAQCVSTKFSELDRSLPPLIHCPVC | | . |..|.| | | |. ||.| CPICLE-------PVVLPCGH-FCY-CI----------------CPIC |
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| Zf-C3HC4 | bon.AA | zf-C3HC4 | 83-130 | 18 | 0.000701 | 12.27 | Pfam | 1-48 (48) | Show / Hide |
Range on Protein: 83-130 Range on HMM: 1-48/48 Sequence Identity: 18% (10 aa) CVYCAQLLGSNDRPKLLECLHV-----ACAQCVSTKFSELDRSLPPLIHCPVC | | . . . .| ...|.| | |... ... ... . ||.| CWICHCEWKDPNNPLIHPCGHRGSLKWFCHSCIKRWWNH-SGNTQ----CPIC |
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| BBOX | bon.AA | BBOX | 173-220 | 23 | 1.2e-08 | 36.01 | SMART | 1-51 (51) | Show / Hide |
Range on Protein: 173-220 Range on HMM: 1-51/51 Sequence Identity: 23% (12 aa) AASIQCSSCSDGAVATSWC-VDCSEYICDSCVQA--HQRLKITKDHTIKPK .. |... ....|. .| .||.. .|. | .. ||. | ...|...| HRPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL |
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| Zf-B_box | bon.AA | zf-B_box | 174-220 | 25 | 8.2e-08 | 35.58 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 174-220
Range on HMM: 1-45/45
Sequence Identity: 25% (12 aa)
ASIQCSSCSDGAVATSWCVDCSEYICDSCVQA-HQRLKITKDHTIKPK
|. . . .. .| ||.. ||..|... |.. . .|.||..|
QM-YCPEHPE-EPLEYYCQDCQQCICEDCAVHGHKGNG-FKKHTVVPI
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| PHD | bon.AA | PHD | 196-205 | 30 | 5.264573 | 1.61 | Pfam | 45-54 (54) | Show / Hide |
Range on Protein: 196-205 Range on HMM: 45-54/54 Sequence Identity: 30% (3 aa) EYICDSCVQA |..|..|. . EWYCPRCKCC |
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| BBOX | bon.AA | BBOX | 235-276 | 29 | 6.3e-11 | 43.55 | SMART | 1-51 (51) | Show / Hide |
Range on Protein: 235-276 Range on HMM: 1-51/51 Sequence Identity: 29% (15 aa) DKLHMCQLHP-QEKLSLFC-ETCDKLTCRDCQLS-DH------RDHKYKFA .. ||. | |.. .|| |.|... |.|| .| .| |.|.... HRPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL |
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| Zf-B_box | bon.AA | zf-B_box | 236-276 | 26 | 4.4e-10 | 44.57 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 236-276 Range on HMM: 1-45/45 Sequence Identity: 26% (12 aa) KLHMCQLHPQEKLSLFCETCDKLTCRDCQLSDHRD-----HKYKFA . .|..||.|.|...|..|... |.|| ...|.. |... QM-YCPEHPEEPLEYYCQDCQQCICEDCAVHGHKGNGFKKHTVVPI |
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| BBC | bon.AA | BBC | 283-409 | 26 | 1.4e-42 | 148.72 | SMART | 1-132 (132) | Show / Hide |
Range on Protein: 283-409 Range on HMM: 1-132/132 Sequence Identity: 26% (35 aa) SRQALSTLVSEINYKRFLLSSATKVIDDRQQLIH-----DKKKDLIKEITAMAVKITNTVNTRGKQLIMRLNEVCDSKLKVLVEKKETLQLLSDNTDHCI |..|.........|.. ...|.| |....| .. ....| ..|.|. .. |..|.|.|...|.|.|.|. |.|.| ....|.. ......||. HREKLEQHLTKLRKKHWECEDAMKQIQNIIQQVQPGHVDENHEDVEQCIRAHFDDLMNWLNRRKKMMLMDLDEQCENKQKWLMQQMQTMTQKQEQLEHCC DFMQNALEKGSDFAILSSKKSLVRHLQKLKCQ .|.|.||..|.....|.|||........|..| QFCQWALNMGDCTEFLQSKKLIIFQCCHLHKQ |
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| PHD | bon.AA | PHD | 899-946 | 33 | 1e-14 | 47.54 | Pfam | 1-54 (54) | Show / Hide |
Range on Protein: 899-946 Range on HMM: 1-54/54 Sequence Identity: 33% (19 aa) WCAVCLD-----GGELMCCD-KCPKVFHQNCHIPAIS--SLPDESESWQCLLCVNI .|.|| . .|...||| .||. ||| || | .. .|.. |.| |.. YCCVCQKCDWDDDGDMICCDNGCPRWFHQYCHGPPLEPEEIPEG--EWYCPRCKCC |
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| PHD | bon.AA | PHD | 899-944 | 29 | 3.2e-12 | 47.83 | SMART | 1-39 (39) | Show / Hide |
Range on Protein: 899-944 Range on HMM: 1-39/39 Sequence Identity: 29% (14 aa) WCAVCLDGGELMCCD-KCPKVFHQNCHIPAISSLPDESESWQCLLCV .| || . | ...|| .|.. .|| |. |. . .... |.| |. YC-VCGK-G-MIQCDPGCDRWYHQ-CLGPPLE---PPDG-WYCPRCR |
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| RING | bon.AA | RING | 900-943 | 18 | 0.014736 | 4.35 | SMART | 1-23 (23) | Show / Hide |
Range on Protein: 900-943 Range on HMM: 1-23/23 Sequence Identity: 18% (8 aa) CAVCLDGGELMCCDKCPKVFHQNCHIPAISSLPDESESWQCLLC |..||. ... .| |.. | | .| CPICLE----PVVLPCGH-FCY-CI---------------CPIC |
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| BROMO | bon.AA | BROMO | 964-1071 | 24 | 2.9e-20 | 74.56 | SMART | 1-118 (118) | Show / Hide |
Range on Protein: 964-1071 Range on HMM: 1-118/118 Sequence Identity: 24% (30 aa) SALELRILQRICLELYCQYEQS-----------LNFREPESPA---NTSYYEIVSSPMSLDVIRTRLDPSSPNHYKDIAGFVSDVRLIFSNTYLFYQEDT . .. .|... |..|. ... |..| .. ||.|. ||.|. |. .|. ..|... || |..|.|.| . .. .|. DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLE---NHQYQSMEEFVDDFMLMFNNCMTYNEPDS KTYSNAKYLENFFEEQLAKWLP |. || |..||||.... | EVYKMAKKLQKFFEEKWREFPP |
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| Bromodomain | bon.AA | Bromodomain | 971-1057 | 23 | 2.1e-17 | 59.02 | Pfam | 1-89 (89) | Show / Hide |
Range on Protein: 971-1057 Range on HMM: 1-89/89 Sequence Identity: 23% (22 aa) LQRICL--ELYCQYEQSLNFREP---ESPANTSYYEIVSSPMSLDVIRTRLDPSSPNHYK-DIAGFVSDVRLIFSNTYLFYQEDTKTYSNAKY ...|. ... . . .|..| . .. ||.|.. ||.|. |. .| |.|. ||.| |..|...| . .. .|. | |.. CDQIMDMKYIMEHP-ICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKL---KNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK |
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