Gene FGTK8 (M.brevicollis)

FGTK8

Species: M.brevicollis
Alias: FGTK8
External Links:
Annotation:

Classification

Group: TK
Family: FGTK

Sequence

Name Sequence Type Origin Length Description Download
FGTK8.AA Protein None 530 None Fasta, JSON
FGTK8.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of FGTK8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase FGTK8.AA FGTK 226-487 48 1.5e-194 652.59 In-house 1-302 (302) Show / Hide 
Range on Protein: 226-487
Range on HMM: 1-302/302
Sequence Identity: 48% (147 aa)

LTFQRGLGAGNFGSVYKALLKGYPVP-----VAVKTFDKVAGGDLKAPMLEAAMLHALSVHPSIINLIAIVHDMSPIQLVLELAQHGDLRSWLRAQVAVN
|..|..||.||||.||||........     |||||||.|...|.||.|.|||..|....||.|..|||.|||..||.||||.|.||||||.||.|.|.|
LQDQPPLGKGNFGTVYKAIPNRHREQFQHQVVAVKTFDDVQMMDYKAVMMEAALMHMACDHPHIVQLIAVVHDCMPIALVLEYADHGDLRSFLRQQDAHN

PSKRRQVLTQTAAGVCFLHACGVLHRDLAARNVLVMEDT-MTQVQVKLADFGLSRYVDDEANYYRASAEEDMPFRWMAPETLLHRRYSPASDVWSLGVLF
.....|.......|.|..|.|...|||.|.||||..... |...|.|||||||||||.|...|||||...||||||||||.|.|.|.|||||||||||..
QEMQLQWMAHITSGLCHVHDCQLVHRDMACRNVLLFSRPHMACPQAKLADFGLSRYVSDDHDYYRASQLDDMPFRWMAPEALRHGRFSPASDVWSLGVTI

WETMEGGATPYRGATLQQIMEQLTSQQRLELSPGHESLFELDMTR----------------------------------LLRDMWAARPEARVSALEVLH
||....|.|||...|.|.|.|.|.|.|||.||.....|..|.|||                                  ||..||.|.||.|.||.||.|
WEIFNQGQTPYGERTMQMILEFLQSGQRLDLSHIPPALHHLYMTRNCLYFPFAMLGTAPWDPHVLLPTSCCCWCVLHPRLLTQMWHANPERRPSAREVVH

LL
.|
AL
Kinase FGTK8.AA TK 226-487 19 3.4e-84 282.06 In-house 1-486 (486) Show / Hide 
Range on Protein: 226-487
Range on HMM: 1-486/486
Sequence Identity: 19% (93 aa)

LTFQRGLGAGNFG---SVYKALLKGYP-------------------------VPVAVKTFDKVAGGDLKA-----------------PMLEAAMLHA-LS
.|. . ||.|.||    |||....| .                         .|||||.  . .. . ..                  ..|..|... | 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

VHPSIINLIAIVHDM------------SPIQLVLELAQHGD----LRSWLRAQVA---------------------------------------------
 || |..|......              |. .|.|...|||    ||..||.                                                
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VNPSKRRQVLTQTAAGVCFLHAC------GVLHRDLAARNVLVMEDT-------MTQVQVKLADFG---
                               ...  .     | |.|  .||..      .. ||||||||.|| |.        ... ..|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRYVDDEANYYRAS-----------------------AEEDMPFRWMAPETLL---------HRRYSPASDVWSLGVLFWETMEGGATPYR---
     |.|..... .|||.|                           .|.||||||.|.         .......|||||.||| || .  |..||    
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

--------GATLQQIMEQLTSQQRL----------ELSPGHESLFE--------------LDMTRLLRDMWAARPEARVSALEVLHLL
        | ..|..||.|.. .||           . .    .                 .. .|... |.. || | .  .... |
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase FGTK8.AA TyrKc 226-487 30 5.4e-76 259.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 226-487
Range on HMM: 1-280/280
Sequence Identity: 30% (90 aa)

LTFQRGLGAGNFGSVYKALLKGYPVPVAVKTFDKVAGGDLKAPMLEAAMLHAL-SVHPSIINLIAIVHDM-------SPIQLVLELAQHGDLRSWLRAQV
.|. . || |.|| |||. .|   ..||||.  . |   ... | || ... |   || |..|.... .         |. .|.|.. ||||.. ||.  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

A-VNPSKRRQVLTQTAAGVCFLHACGVLHRDLAARNVLVMEDTMTQVQVKLADFGLSRYVDDE------ANYYRASA--EED--MPFRWMAPETLLHRRY
  .....  .  .| |.|  .||  .. ||||||||.|| |.     .|| .||||||...|.        |||..    ..  .| ||||||.. ....
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SPASDVWSLGVLFWETMEGGATPYRG-----ATLQQIMEQLTSQQRLELSPGH-ESL----FELDMTRLLRDMWAARPEARVSALEVLHLL
...||||| ||. || .  |..|| |      . |...|.. .  |..  | . . .       .| .. .. |.. || | .  |. ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase FGTK8.AA Pkinase_Tyr 226-449 34 6.7e-72 244.13 Pfam 1-236 (270) Show / Hide 
Range on Protein: 226-449
Range on HMM: 1-236/270
Sequence Identity: 34% (83 aa)

LTFQRGLGAGNFGSVYKALLK----GYPVPVAVKTFDKVAGGD---LKAPMLEAAMLHALSVHPSIINLIAIVH-DMSP--IQLVLELAQHGDLRSWLRA
.|| . ||.|.||.|||. .|    .  .|||||.    |  .   ... | ||.... |  || |..|....  .  |  | .|.|...||||.. ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----QVAVNPSKRRQVLTQTAAGVCFLHACGVLHRDLAARNVLVMEDTMTQVQVKLADFGLSRYVDDEANYY-RASAEEDMPFRWMAPETLLHRRYSPAS
    . .....   |  .| |.|  .|.. .  ||||||||.|| |   .  .|| .||||.|..  .  || |.. . ..| .||||| . ..... .|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NN-VVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS

DVWSLGVLFWETMEGGATP-YRGATLQQIMEQL-TSQQRLE
|||| ||| || .  |..| | | . ....|..  . .|..
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP
Kinase FGTK8.AA UTK 226-449 32 4.2e-68 232.08 In-house 1-262 (296) Show / Hide 
Range on Protein: 226-449
Range on HMM: 1-262/296
Sequence Identity: 32% (87 aa)

LTFQRGLGAGNFGSVYKALLK-----GYPVPVAVKTFDKVAGGDLKAP------MLEAA---MLHALSVHPSIINLIAIVHDMSPIQLVLELAQHGDLRS
. . | ||.|.|| |.|| ..     .| . ||||. . . . . ..|      |.||.   |. ... ||....|.... . .|. .|.|... |||||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ-HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRS

WLR--------AQVAVNPSKRRQVLTQTAAGVCFLHACGVLHRDLAARNVLVMED----TMTQVQVKLADFG---LSRYVDD--------EANYYRASAE
 ||        ......  .| .   . |.|. .|| ||. ||||||||.|| ..    .    ..|.||||   .||.| .        |..||.|.  
YLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWH-CMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQ

EDMPFRWMAPETLLHR-RYSPASDVWSLGVLFWETMEGGATPYRGATLQQIMEQLTSQ--QRLE
. .|.|||||| | |. |.. .|||||.||. ||.. .|..|| | . .|. .|.. .  .|..
DRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMP
Kinase FGTK8.AA RTKA 226-465 29 1.2e-63 217.76 In-house 1-314 (314) Show / Hide 
Range on Protein: 226-465
Range on HMM: 1-314/314
Sequence Identity: 29% (93 aa)

LTFQRGLGAGNFGSVYKA-LLKG------YPVPVAVKTFD--KVAG-GDLKAPMLEAAMLHALSVHPSIINLIAIV---HD---MSPIQLVLELAQHGDL
.. .. .| |.|. ||.| |. .       | .||.|  |    .. ..| | | |.  ||..  .| || |  ..    |    | . .|.| ..|| |
MQVRHVVGHGHFSQVYQASLQDMEDEMRQGPQCVAIKECDDLMLNDKTTLSAWMREIMLLHSMRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGNL

RSWLRAQVA-----------------------VNPSKRRQVLTQTA-------AGVCFLHACGVLHRDLAARNVLVMEDTMTQVQVKLADFGLSRYVDDE
|  .| . .                         .   .|.|.|..        .  .|  ||. |||.||||||||  ..    .||||||||| .  .
RDFVRQHPHFSAPVVATIAMQHSGEPNASPKLLSEAQCHQALLQMCPCWAQVAQAMAYLAKCGIVHRDVAARNVLVMS-LQPAFHCKLADFGLSRVMPSS

ANYYRASAEEDMPFRWMAPETLLHRRYSPASDVWSLGVLFWETMEGGATPYR------------------------------GATLQQIMEQLTSQQRLE
  ||. .|...||||||||| .. |||| .|||||.||| ||   .|.||..                              |  | .|  .| . |.|.
-DYYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQIVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQTLP

LSPGHESLFELDMTRL
..|.  ...   . . 
MPPCCPPCLQRFCFWC
Kinase FGTK8.AA Fer 226-488 29 1.2e-53 181.05 In-house 1-283 (283) Show / Hide 
Range on Protein: 226-488
Range on HMM: 1-283/283
Sequence Identity: 29% (85 aa)

LTFQRGLGAGNFGSVYKA-----LLKG-----YPVPVAVKTF-DKVAGGD-LKAPMLEAAMLHA-LSVHPSIINLIAIVHDMSPIQLVLELAQHGDLRSW
 |..  || |.|| |||.     ..||     ..|.|.||.    .|. . .|  | || ..   .. || .. .. . .|  || .|.|.. .|.|.| 
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYD-HPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSY

LRAQVA--VNPSKRRQVLTQTAAGVCFLHACGVLHRDLAARNVLVMEDTMTQVQVK--LADFGLSRYVDDEANYYRAS-AEEDMPFRWMAPETLLHRRYS
|.   .  |   .. . . | |.|  .||. ...|||.||||.|. .|   .|..|  ..|||.||  .|. . |.   ... .| ||.||||.  . ||
LKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKD---KVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYS

PASDVWSLGVLFWETMEGGATPYRG----ATLQQIMEQLTSQ-QRLELSPGHESLFELDMTRLLR-DMWAARPEARVSALEVLHLLD
|..|||| ||. || .. ||.|| |     .. .. .|.  . .. .  . ... .  .. ...  . |.. || | .. |. . | 
PKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase FGTK8.AA TK-Unique 226-487 27 2.3e-52 178.83 In-house 1-294 (294) Show / Hide 
Range on Protein: 226-487
Range on HMM: 1-294/294
Sequence Identity: 27% (84 aa)

LTFQRGLGAGNFGSVYKALLKGYP------VPVAVKTFD-KVAGGDLKAPMLEAAMLHALSVHPSIINLIAIVHDMS-PIQLVLELAQHGDLRSWLRAQV
|.... .| |.|| |... ..| .      . ||||.   .. . | .. . |..|. .|  || |.... .  . . | ....| .. |.|.. ||   
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

AV-----------------NPSKRRQVLT---------QTAAGVCFLHA--CGVLHRDLAARNVLVMEDTMTQVQVKLADFGLSRYVDDEANYYRASAEE
 .                 ....|.  ..         | | |  .|.   ... ||||.|||||. |      ..|..|||..|.|...  | .   ..
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE----DKVCKICDFGMARDVYTNGVYSMMCSQG

DMPFRWMAPETLL--HRRY-SPASDVWSLGVLFWETMEGGATPYRGATLQQIMEQLTSQQRLELSPGH-ESLFELDMTRLLRDMWAARPEARVSALEVLH
 .| |||||| |.  |. | .. |||||.||| || .  ||.||.|    .|||...   |... ..        .|. |..  |   || |.|  ...|
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSH----EMYNLMKSCWQWEPEERPSFRQIKH

LL
 |
RL
Kinase FGTK8.AA S_TKc 226-487 22 3.1e-49 170.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 226-487
Range on HMM: 1-231/231
Sequence Identity: 22% (62 aa)

LTFQRGLGAGNFGSVYKALLKGYPVPVAVKTFDKVAGGDLKAPMLEAAMLHALSVHPSIINLIAIVHDMSPIQLVLELAQH--GDLRSWLRAQVA-----
 .. | .| | ||.|||.  |.    ||.|  .       .  . | ..|.    || |..|. . .| . . .|.|.. .  |||.. .. .       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-VNPSKRRQVLTQTAAGVCFLHACGVLHRDLAARNVLVMEDTMTQVQVKLADFGLSRYVDDEANYYRASAEEDMPFRWMAPETLLHRRYSP-ASDVWSLG
  ..   | .. |.. .. ..|  |..||||   |.|. |      ..|..||||.| .                  .|||| |    |.. ..|.||.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLFWETMEGGATPYRGATLQQIMEQLTSQQRLELSPGHESLFELDMTRLLRDMWAARPEARVSALEVLH---------LL
....| .  | .|..  ..|......                  ..  ..| ..   || | .| |.|.          .
CILYEMLC-GYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FGTK8.AA Src 226-442 33 5.2e-49 164.62 In-house 1-213 (255) Show / Hide 
Range on Protein: 226-442
Range on HMM: 1-213/255
Sequence Identity: 33% (73 aa)

LTFQRGLGAGNFGSVYKALLKGYPVPVAVKTFDKVAGGDLKAPMLEAAMLHALSVHPSIINLIAIVHDMSPIQLVLELAQHGDLRSWLR-AQVAVNPSKR
... | ||.|.|| |.... .|  ..|||||  .    . .|   ||  .  |. |. ...| |.. .  ||  | |. .|| |  .|.  .   . . .
IKLCRKLGQGQFGEVWMGYWNGN-TKVAVKTLKPGT-MSPEAFLQEAQIMKKLR-HEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLP

RQVL--TQTAAGVCFLHACGVLHRDLAARNVLVMEDTMTQVQVKLADFGLSRYVDDEANYYRASAEEDMPFRWMAPETLLHRRYSPASDVWSLGVLFWET
...   .| |.| ..| .  . ||||||||||| |.      .| ||||| | .... . | |. .  .| .|.||| ....|..  ||||| |.| .| 
QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN----VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEI

MEGGATPYRGATLQQIMEQL
.  | .||.| | .. ..|.
VTYGRVPYPGMTNHEVLQQV
Kinase FGTK8.AA RTKF 226-430 37 1.7e-48 154.22 In-house 1-213 (272) Show / Hide 
Range on Protein: 226-430
Range on HMM: 1-213/272
Sequence Identity: 37% (80 aa)

LTFQRGLGAGNFGSVYKAL---LKGYPVPVAVKTFDKVAGGDLKAPML-EAAMLHALSVHPSIINLIAIVHDMSPIQ-----LVLELAQHGDLRSWL-RA
..    ||.|.|| | ...    ||   |||.|.     . . .  || |.  .     || || .  |.  |.|.      .|.| | |||.|. | . 
IMLGEQLGHGHFGRVHHGYWRQQKGQRQPVAIKHIHTQDMMNWRRQMLRECCAMNRVGQHPHIIQFFGIL--MTPFEQNEMAFVMEFAPHGDMRRYLQQH

QVAVNPSKRRQVLTQ-TAAGVCFLHACGVLHRDLAARNVLVMEDTMTQVQVKLADFGLSRYVDDEANYYRASAEEDMPFRWMAPETLLHRRYSPASDVWS
 |     .  .   |  |    |    |  |||.||||||| ||. .  .||| |||| |       |||   .|. ||||||||   |||... |||||
DVDLGRAHMLDAAHQVVAEAMVFISRQGLVHRDVAARNVLVFEDQPR-MYVKLTDFGLARVLSQHQDYYRSMQNEELPFRWMAPEAIMHRRFTQKSDVWS

LGVLFWETMEGGATPY
 |.. .| . .|  ||
FGMMLFELFTRGDVPY
Kinase FGTK8.AA TKL 232-487 20 5.6e-46 159.08 In-house 1-364 (364) Show / Hide 
Range on Protein: 232-487
Range on HMM: 1-364/364
Sequence Identity: 20% (75 aa)

LGAGNFGSVYKALLKGYP--------VPVAVKTFDK--VAGGDLKA-----------------------PMLEAAMLHALSV-HPSIINLIAIVHDMSP-
.| | || |||. ..| .         .||||.| .  .   ...                          .|  ... ..  || |. ..... . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IQLVLELAQHGDLRSWLRAQVAVNPSKRRQVLTQTAAGVCFLHACG--------VLHRDLAARNVLVMEDTM----------TQVQVK
            . .| |....|.|.. |       ...| .   ..| |...||...        ..||||  .|.|| |.             .. .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LADFGLSRYVDDEA----------------NYYRASAEEDMPFRWMAPETLL----------------HRRYSPASDVWSLGVLFWETMEGGATPYR-GA
..|||||| .. .                 |.  ..  .   .|||||| |                 .. ||...||.| |...|| . .   ||.   
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYDYP

TLQQI---------MEQLTSQQRLELSP--------GHESLFELDMTRLLRDMWAARPEARVSALEVLHLL
  ..|         |     ..|... |         ... .  .| .|. | |.. ||.| |..|.|. |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase FGTK8.AA Pkinase 226-487 22 3e-45 161.08 Pfam 1-293 (293) Show / Hide 
Range on Protein: 226-487
Range on HMM: 1-293/293
Sequence Identity: 22% (67 aa)

LTFQRGLGAGNFGSVYKALLKGYPVPVAVKTFDKVAGGDLKAPML----EAAMLHALSVHPSIINLIAIVHDMSPIQLVLELAQHG----DLRSWLR--A
... | .|.|.||.|||.  ||..  ||||...|.   . |   .    |..... |. || |. |. ...| . | .|.|....|    || ....  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

QVAV--NPSKRRQVLTQTAAGVCFLHACGVLHRDLAARNVLVMEDTMTQVQVKLADFGLSR---YVDDEANYYRASAEEDMPFRWMAPETLL-HRRYSPA
. ..   .   . ...|.. |. ..|..|..||||   |.|. ..  .   ||..||||..   |  .. .. ..   .     .|||| .. .. |.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW-----YMAPEVIRGGQYYGPK

SDVWSLGVLFWETMEGGATPYRGA------TLQQIMEQLTSQQRLELSPGHES----------------LFELDMTRLLRDMWAARPEARVSALEVLHL-
.|.||.|....| . |  .|..|.      . .|....  . .  . .|   |                . . ..  .......  |. | .| ..|.  
VDMWSCGCILYEMLCGR-PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

-L
 .
WF
Kinase FGTK8.AA Abl 226-487 32 1e-44 146.79 In-house 1-252 (252) Show / Hide 
Range on Protein: 226-487
Range on HMM: 1-252/252
Sequence Identity: 32% (85 aa)

LTFQRGLGAGNFGSVYKALLKGYPVPVAVKTFDKVAGGDLKAPMLEAAMLHALSVHPSIINLIAIVHDMSPIQLVLELAQHGDLRSWLRA--QVAVNPSK
.. .  || | .| ||... | .   |||||  |    ...  . |||..  .  || .. |. .    .|  .. |   .| |  .||   .  ...  
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTL-KEDTMEVHEFLKEAAIMKEMK-HPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVV

RRQVLTQTAAGVCFLHACGVLHRDLAARNVLVMEDTMTQVQVKLADFGLSRYVDDEANYYRASAEEDMPFRWMAPETLLHRRYSPASDVWSLGVLFWETM
  .. || | |. .| .   .|||||||| || |. .    ||.|||||.| . |.   | | |    | .| ||| | . ..|  ||||  ||| ||  
LLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHI----VKVADFGLARMMKDDT--YTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIA

EGGATPYRGATLQQIMEQLTSQQRLELSPGHESLFELDMTRLLRDMWAARPEARVSALEVLHLL
  | .|| |  |... ..|    |.|  .|       .. .|.|  |  ..  | |  |. | .
TYGMSPYPGIDLSHVYHKLEKGYRMERPEG----CPPKVYELMRQCWQWSHTDRPSFKEIHHAM