Gene RTKC5 (M.brevicollis)

RTKC5

Species: M.brevicollis
Alias: RTKC5
External Links:
Annotation:

Classification

Group: TK
Family: RTKC

Sequence

Name Sequence Type Origin Length Description Download
RTKC5.AA Protein None 2202 None Fasta, JSON
RTKC5.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of RTKC5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NCD3G RTKC5.AA NCD3G 13-37 24 0.163449 6.46 Pfam 27-51 (54) Show / Hide 
Range on Protein: 13-37
Range on HMM: 27-51/54
Sequence Identity: 24% (6 aa)

TCVDCFGNSYADETGLASCKDCSTG
.|..| ...| ..|.  .|..|  .
DCIPCPEGEYSNTTDSYTCTPCPED
GCC2_GCC3 RTKC5.AA GCC2_GCC3 5-37 32 7.196314 2.54 Pfam 1-34 (49) Show / Hide 
Range on Protein: 5-37
Range on HMM: 1-34/49
Sequence Identity: 32% (11 aa)

GKVGAEGG-TCVDCFGNSYADETGLASCKDCSTG
|     |. .|. |  ..| .| |  ||. |. |
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPG
TNFR_c6 RTKC5.AA TNFR_c6 17-36 22 37.419446 0.54 Pfam 1-21 (41) Show / Hide 
Range on Protein: 17-36
Range on HMM: 1-21/41
Sequence Identity: 22% (5 aa)

CFGN-SYADETGLAS-CKDCST
|  . .| | .. .. |. |..
CPPGKTYTD-WNHVPHCLSCTR
GCC2_GCC3 RTKC5.AA GCC2_GCC3 43-89 33 4e-06 22.99 Pfam 2-49 (49) Show / Hide 
Range on Protein: 43-89
Range on HMM: 2-49/49
Sequence Identity: 33% (16 aa)

ENSNGLNVGCEMCDIGTYQSGNDHTQCLTCPEG-KLATSEGATVCYDC
. .|. .  ||.| .||||.  . . |. || | .   ..|.|  .||
TYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
NCD3G RTKC5.AA NCD3G 52-78 33 8.7e-05 16.18 Pfam 28-54 (54) Show / Hide 
Range on Protein: 52-78
Range on HMM: 28-54/54
Sequence Identity: 33% (9 aa)

CEMCDIGTYQSGNDHTQCLTCPEGKLA
|. |. |.|..  | ..|..|||.  .
CIPCPEGEYSNTTDSYTCTPCPEDQWP
TNFR RTKC5.AA TNFR 55-86 20 0.049425 7.2 SMART 1-50 (50) Show / Hide 
Range on Protein: 55-86
Range on HMM: 1-50/50
Sequence Identity: 20% (10 aa)

CDI--GTYQSGNDH-----TQ--CL--TCPE---GKLATSEGAT----VC
|    |.|.. . |     .   |   .||.   |. .....      ||
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC5.AA TNFR_c6 55-72 40 0.478524 7.01 Pfam 1-19 (41) Show / Hide 
Range on Protein: 55-72
Range on HMM: 1-19/41
Sequence Identity: 40% (8 aa)

CDIG-TYQSGNDH-TQCLTC
|. | ||..   |  .|| |
CPPGKTYTD-WNHVPHCLSC
NCD3G RTKC5.AA NCD3G 165-193 27 4.7e-05 16.99 Pfam 26-54 (54) Show / Hide 
Range on Protein: 165-193
Range on HMM: 26-54/54
Sequence Identity: 27% (8 aa)

YECKACPGGTYSASSGATQCTAVSAGYVA
..|  ||.|.|| ......||    .. .
WDCIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKC5.AA NCD3G 113-135 30 0.000334 14.45 Pfam 27-52 (54) Show / Hide 
Range on Protein: 113-135
Range on HMM: 27-52/54
Sequence Identity: 30% (8 aa)

TCEPCAQNEYLS--GT-SCVSCPVGH
.|.||. .||..  .. .|..|| ..
DCIPCPEGEYSNTTDSYTCTPCPEDQ
GCC2_GCC3 RTKC5.AA GCC2_GCC3 151-186 30 0.005041 12.8 Pfam 1-30 (49) Show / Hide 
Range on Protein: 151-186
Range on HMM: 1-30/49
Sequence Identity: 30% (11 aa)

GTYLAVITEASETTYECKACPGGTYSASSGATQCTA
|||.         ...| .|| |||  ..| . | .
GTYYN------KGQNPCEPCPRGTYQNEEGQDSCIP
GCC2_GCC3 RTKC5.AA GCC2_GCC3 112-145 31 0.848485 5.56 Pfam 9-49 (49) Show / Hide 
Range on Protein: 112-145
Range on HMM: 9-49/49
Sequence Identity: 31% (13 aa)

GTCEPCAQNEY---LSGTSCVSCPVG-H---IQSATDASLC
..||||  . |    . .|| .||.| .   .. .| .| |
NPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
NCD3G RTKC5.AA NCD3G 145-154 50 2.227924 3.09 Pfam 28-37 (54) Show / Hide 
Range on Protein: 145-154
Range on HMM: 28-37/54
Sequence Identity: 50% (5 aa)

CVPCAAGTYL
|.||..|.|.
CIPCPEGEYS
TNFR_c6 RTKC5.AA TNFR_c6 117-131 26 2.285441 4.69 Pfam 1-19 (41) Show / Hide 
Range on Protein: 117-131
Range on HMM: 1-19/41
Sequence Identity: 26% (5 aa)

CAQN-EYLS-GT-S-CVSC
|... .|.. .. . |.||
CPPGKTYTDWNHVPHCLSC
TNFR_c6 RTKC5.AA TNFR_c6 170-184 35 3.244625 4.17 Pfam 1-16 (41) Show / Hide 
Range on Protein: 170-184
Range on HMM: 1-16/41
Sequence Identity: 35% (6 aa)

CPGG-TYSASSGA-TQC
|| | ||.. ..   .|
CPPGKTYTD-WNHVPHC
GCC2_GCC3 RTKC5.AA GCC2_GCC3 206-223 38 0.002573 13.75 Pfam 1-18 (49) Show / Hide 
Range on Protein: 206-223
Range on HMM: 1-18/49
Sequence Identity: 38% (7 aa)

GMYSSGGTDTCHSCPAGS
|.|...|. .|..|| |.
GTYYNKGQNPCEPCPRGT
TNFR_c6 RTKC5.AA TNFR_c6 203-219 31 1.82971 5.02 Pfam 1-19 (41) Show / Hide 
Range on Protein: 203-219
Range on HMM: 1-19/41
Sequence Identity: 31% (6 aa)

CGLG-MYSSGGT-DTCHSC
|  |  |.. .. ..| ||
CPPGKTYTDWNHVPHCLSC
NCD3G RTKC5.AA NCD3G 273-300 39 1.5e-05 18.41 Pfam 27-54 (54) Show / Hide 
Range on Protein: 273-300
Range on HMM: 27-54/54
Sequence Identity: 39% (11 aa)

ECDFCPANTYSDTRNAPSCTSCPTDTIS
.|  ||...||.| .. .||.|| |  .
DCIPCPEGEYSNTTDSYTCTPCPEDQWP
TNFR RTKC5.AA TNFR 236-274 20 0.001245 19.31 SMART 1-50 (50) Show / Hide 
Range on Protein: 236-274
Range on HMM: 1-50/50
Sequence Identity: 20% (10 aa)

CTL-GTSYTNDEH-----IQCLTAS--SCAK---GSYITAAATTSSDREC
|.  .  |.....      .||  .  .| .   | | ..  |  |...|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
GCC2_GCC3 RTKC5.AA GCC2_GCC3 259-299 28 0.008573 12.05 Pfam 1-37 (49) Show / Hide 
Range on Protein: 259-299
Range on HMM: 1-37/49
Sequence Identity: 28% (12 aa)

GSYITAAATTSSDRECDFCPANTYSDTRNAPSCTSCPTD-TI
| |  .        .|  || .|| .. .  || .||   |.
GTYYNKGQ-----NPCEPCPRGTYQNEEGQDSCIPCPPGKTT
TNFR_c6 RTKC5.AA TNFR_c6 277-294 47 0.046464 10.47 Pfam 1-19 (41) Show / Hide 
Range on Protein: 277-294
Range on HMM: 1-19/41
Sequence Identity: 47% (9 aa)

CPAN-TYSDTRNAPSCTSC
|| . ||.|. ..| |.||
CPPGKTYTDWNHVPHCLSC
TNFR_c6 RTKC5.AA TNFR_c6 236-274 29 0.741589 6.36 Pfam 1-41 (41) Show / Hide 
Range on Protein: 236-274
Range on HMM: 1-41/41
Sequence Identity: 29% (12 aa)

CTLGTSYTNDEH-IQCLTASSCAK-GSYITAAATTSSDREC
|  | .|| . |  .||  ..| . |.| ..  |  ....|
CPPGKTYTDWNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
GCC2_GCC3 RTKC5.AA GCC2_GCC3 317-344 39 0.003137 13.47 Pfam 1-28 (49) Show / Hide 
Range on Protein: 317-344
Range on HMM: 1-28/49
Sequence Identity: 39% (11 aa)

GEFYSQEASGCEDCPAGKYTSGAGRTSC
|..|. . . || || | | . .|..||
GTYYNKGQNPCEPCPRGTYQNEEGQDSC
TNFR RTKC5.AA TNFR 330-368 28 0.004944 17.32 SMART 1-50 (50) Show / Hide 
Range on Protein: 330-368
Range on HMM: 1-50/50
Sequence Identity: 28% (14 aa)

CP--AGKYTSGAGRT----SCDSYD--NCLA---GQYVTATPTPTSNRAC
|.  .| |..  . |     | . .  .|     |||...  |.|||. |
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC5.AA TNFR_c6 330-368 35 0.136603 8.87 Pfam 1-41 (41) Show / Hide 
Range on Protein: 330-368
Range on HMM: 1-41/41
Sequence Identity: 35% (15 aa)

CPAG-KYTSGAGR-TSCDSYDNCLA-GQYVTATPTPTSNRAC
|| |  ||.  .    | |   |   |||...  |.|.|. |
CPPGKTYTD-WNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
NCD3G RTKC5.AA NCD3G 368-388 42 0.865357 4.31 Pfam 28-48 (54) Show / Hide 
Range on Protein: 368-388
Range on HMM: 28-48/54
Sequence Identity: 42% (9 aa)

CAVCPAGKYSDSLNAASCTIC
|  ||.| ||.. .. .|| |
CIPCPEGEYSNTTDSYTCTPC
NCD3G RTKC5.AA NCD3G 327-344 33 3.282562 2.59 Pfam 28-45 (54) Show / Hide 
Range on Protein: 327-344
Range on HMM: 28-45/54
Sequence Identity: 33% (6 aa)

CEDCPAGKYTSGAGRTSC
|..||.| | .  . ..|
CIPCPEGEYSNTTDSYTC
TNFR_c6 RTKC5.AA TNFR_c6 371-388 40 9.345797 2.6 Pfam 1-19 (41) Show / Hide 
Range on Protein: 371-388
Range on HMM: 1-19/41
Sequence Identity: 40% (8 aa)

CPAG-KYSDSLNAAS-CTIC
|| |  |.|  | .. |. |
CPPGKTYTD-WNHVPHCLSC
GCC2_GCC3 RTKC5.AA GCC2_GCC3 374-388 26 17.802776 1.26 Pfam 1-14 (49) Show / Hide 
Range on Protein: 374-388
Range on HMM: 1-14/49
Sequence Identity: 26% (4 aa)

GKYSDSLNAASCTIC
| |... . . |. |
GTYYNKGQ-NPCEPC
TNFR_c6 RTKC5.AA TNFR_c6 314-327 23 35.938629 0.6 Pfam 1-16 (41) Show / Hide 
Range on Protein: 314-327
Range on HMM: 1-16/41
Sequence Identity: 23% (4 aa)

CQPG-EFYSQEA--SGC
|.|| .... ..  . |
CPPGKTYTD-WNHVPHC
TNFR RTKC5.AA TNFR 431-471 22 0.048032 7.33 SMART 1-50 (50) Show / Hide 
Range on Protein: 431-471
Range on HMM: 1-50/50
Sequence Identity: 22% (11 aa)

CSVERSEYQPNGGA----DSCLTLS--TCAP---GQYVTTFATSSTDRAC
|     .|.  ...    . ||  .  .| |   |||..   |.  .. |
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
GCC2_GCC3 RTKC5.AA GCC2_GCC3 419-448 32 0.342833 6.84 Pfam 1-29 (49) Show / Hide 
Range on Protein: 419-448
Range on HMM: 1-29/49
Sequence Identity: 32% (10 aa)

GPTSSTAR-TCVACSVERSEYQPNGGADSCL
|  ...   .|..|  .|  ||...| |||.
GTYYNKGQNPCEPC--PRGTYQNEEGQDSCI
TNFR_c6 RTKC5.AA TNFR_c6 431-471 25 1.722027 5.11 Pfam 1-41 (41) Show / Hide 
Range on Protein: 431-471
Range on HMM: 1-41/41
Sequence Identity: 25% (11 aa)

CSVERSEYQPNGGA-DSCLTLSTCAP-GQYVTTFATSSTDRAC
|.   ..|.   .  . ||  ..| | |||.. . |.  .. |
CPPG-KTYTD-WNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 RTKC5.AA TNFR_c6 474-512 30 0.007632 13.15 Pfam 1-41 (41) Show / Hide 
Range on Protein: 474-512
Range on HMM: 1-41/41
Sequence Identity: 30% (13 aa)

CAAG--FTATTNTATQCNTWTTCRA-GEVQTMPPTITSDRVC
|. |  .|. .|.. .|.  |.|   |.. . | | |...||
CPPGKTYTD-WNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
TNFR RTKC5.AA TNFR 474-512 22 0.010457 14.26 SMART 1-50 (50) Show / Hide 
Range on Protein: 474-512
Range on HMM: 1-50/50
Sequence Identity: 22% (11 aa)

CA---AGFTATTNTA---TQCNTWT--TCRA---GEVQTMPPTITSDRVC
|      .... |      .|  ..  .|.    |.. . | | ||..||
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR RTKC5.AA TNFR 515-551 18 0.051648 7.0 SMART 1-50 (50) Show / Hide 
Range on Protein: 515-551
Range on HMM: 1-50/50
Sequence Identity: 18% (9 aa)

CA--SGTFAANA------TYCQPWS--DCPA---GSYVNYAPSTYQDRIC
|    |.. .          |.|..   ||    | |.    .  ....|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
GCC2_GCC3 RTKC5.AA GCC2_GCC3 536-570 25 2.20655 4.21 Pfam 1-30 (49) Show / Hide 
Range on Protein: 536-570
Range on HMM: 1-30/49
Sequence Identity: 25% (9 aa)

GSYVNYAPSTYQDRICRSCTVGTFSTTANAATCTP
| | |         .| .|  ||.  ...  .| |
GTYYN-----KGQNPCEPCPRGTYQNEEGQDSCIP
NCD3G RTKC5.AA NCD3G 532-560 27 5.647217 1.89 Pfam 30-54 (54) Show / Hide 
Range on Protein: 532-560
Range on HMM: 30-54/54
Sequence Identity: 27% (8 aa)

DCPAGSYVNYAPSTYQDRICRSCTVGTFS
.||.|.|.|    .|.   | .|. .  .
PCPEGEYSNTT-DSYT---CTPCPEDQWP
HYR RTKC5.AA HYR 1127-1212 39 1.8e-12 43.06 Pfam 1-86 (86) Show / Hide 
Range on Protein: 1127-1212
Range on HMM: 1-86/86
Sequence Identity: 39% (34 aa)

SDIIPPYFLGCPANQYATALAPNYTVAVTWTEPIAFDNVA-LDEATLQRSHAPGDYFSVLNSPHTVTYDIRDEAALAAETCSFRIYV
 |. || .. || |  .|.   . ||.|.|||| |.||          |.. ||| |.|  . .||||  .|.|   |.||.|.. |
VDTTPPTVENCPNNIFRTVELGTSTVNVFWTEPTATDNSGDIQANLISRTAQPGDFFPVGEQ-TTVTYTFQDNAGNQADTCTFTVTV
HYR RTKC5.AA HYR 1420-1433 35 3.180128 2.76 Pfam 1-14 (86) Show / Hide 
Range on Protein: 1420-1433
Range on HMM: 1-14/86
Sequence Identity: 35% (5 aa)

FDDIPPSIRSCPTS
 |. ||.. .||..
VDTTPPTVENCPNN
HYR RTKC5.AA HYR 1640-1697 31 4.2e-08 28.71 Pfam 24-86 (86) Show / Hide 
Range on Protein: 1640-1697
Range on HMM: 24-86/86
Sequence Identity: 31% (20 aa)

TTRVVNYTRAEASDN-D--AVANLTCSHEPGDSYPIG-RTAVVCNATDMSGNLN-SCEFVVVV
.| .| .|  .|.|| .  ..   . ...|||. |.|  | |   ..| .|| . .| | | |
STVNVFWTEPTATDNSGDIQANLISRTAQPGDFFPVGEQTTVTYTFQDNAGNQADTCTFTVTV
Kinase RTKC5.AA RTKC 1780-2036 70 4.4e-219 729.89 In-house 1-261 (261) Show / Hide 
Range on Protein: 1780-2036
Range on HMM: 1-261/261
Sequence Identity: 70% (185 aa)

LTMLEELGRGAFGLVYKALFEESP-NPGFLVAVKSLHHTAGVSDRQELLEEAAVMVQLDHPNVVKLVGVVTVGEPLLVVLEYCEKGSLKSYLENNPDVSE
||.|.||||||||.|||||.||.. .||.|||.|||||||...||||||||||||.|..|||||.|.||||||.|.|||||.||.|||||||.||||..|
LTLLDELGRGAFGIVYKALLEEPGGMPGYLVACKSLHHTAMDNDRQELLEEAAVMAQFEHPNVVHLIGVVTVGKPILVVLEFCERGSLKSYLMNNPDCTE

SQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDALMRCRIADFGLAREE--NDGADA-YYRSRSGNLPVRWTAPEALDERKFSESTDVWAAGILFYEI
.||.|||.|...||||||...|.|||.|||||||.....|..||||||||.  ||.... ||||||||||||||||||||.|||||..||||.|||.|||
HQKVRFCYQCASGMEHIHSFGFIHRDVAARNVLLSSDLTCKVADFGLARESPCNDDSHEAYYRSRSGNLPVRWTAPEALDDRKFSEKSDVWAFGILMYEI

YTKAGLPYDGWSNQRVWVEVSAGYRLPCPESCSKAVYDLMLACWDETPGFRPSFGKLAEQL
||||..||||||||||||||.|||||||||.|.|.|||.|..||..||..||.|......|
YTKAEMPYDGWSNQRVWVEVCAGYRLPCPEDCHKEVYDMMMDCWMHTPHDRPTFSEVVHWL
Kinase RTKC5.AA TyrKc 1780-2036 37 3.6e-121 409.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 1780-2036
Range on HMM: 1-280/280
Sequence Identity: 37% (110 aa)

LTMLEELGRGAFGLVYKALFEESPNPGFLVAVKSLHHTAGVSDRQELLEEAAVMVQL--DHPNVVKLVGVVTVG-------EPLLVVLEYCEKGSLKSYL
.|....||.|||| |||.           ||||.|.. |    |.....|| .| .|  .|||.|.|.||.| .       |||..|.||...|.||.||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

ENNPD-VSESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDALMRCRIADFGLAREENDG-----ADAYYRSR---SGN--LPVRWTAPEALDERKF
 .. . .. .... || ||. |||..|.||..||||||||.|...  ...|.||||.|.  |.     .. |||..   .|.  ||.||.|||.....||
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SESTDVWAAGILFYEIYTKAGLPYDG-----WSNQRVWVEVSAGYRLPCPES--------CSKAVYDLMLACWDETPGFRPSFGKLAEQL
.. .|||. |.. .||.|  . || |      |||.|   | .|||.|.|..        |....|..|. ||.| |  ||.|  . |..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKC5.AA Pkinase_Tyr 1780-2036 40 1.5e-117 398.74 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1780-2036
Range on HMM: 1-270/270
Sequence Identity: 40% (111 aa)

LTMLEELGRGAFGLVYKALFE-ESPNPGFLVAVKSLHHTAGVSD--RQELLEEAAVMVQL-DHPNVVKLVGVVT-VGEP--LLVVLEYCEKGSLKSYLEN
.|....||.|||| |||.    .  |..  ||||.| ..|  ..  |.....||..| || .|||.|.|.||.|  |||  ...|.||...|.|..|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----NPDVSESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDALMRCRIADFGLAREENDGADAY-YRSRSGNLPVRWTAPEALDERKFSESTDVWA
    .. .. .... .| ||. |||. ..||..||||||||.|..  . ..|.||||||      | | . . .| ||..|.|||.. ..||.. .|||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

AGILFYEIYTKAGLP-YDGWSNQRVWVEV-SAGYRLPCPESCSKAVYDLMLACWDETPGFRPSFGKLAEQL
 |.| .||.|  . | | |.||..|   .   |||.|||| |.. .||||. ||.. |  ||.|  . |||
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKC5.AA TK 1780-2036 24 1.5e-114 385.59 In-house 1-486 (486) Show / Hide 
Range on Protein: 1780-2036
Range on HMM: 1-486/486
Sequence Identity: 24% (118 aa)

LTMLEELGRGAFG---LVYKALFEESP---NPGF-------------------LVAVKSLHHTAGVSDRQELL-------------EEAAVMVQLD----
.|....||.|.||    |||.. .. .   ...|                    |||| |. ... |......             |||..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVKLVGVVTVG------------EPLLVVLEYCEKGS----LKSYLENNPD---------------------------------------------
 |||.|.|.||.| |            ||...|.||...|.    |..|| ....                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VSESQKIRFCKQISLGMEHIHEK------NFVHRDLAARNVLLDALMR-----------CRIADFG---
                               ..  |.. .| ||. |||..|.|      |||||||||||.|..  ..           |.|||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAREENDG----------------------ADAYYRSRSG-NLPVRWTAPEALD---------ERKFSESTDVWAAGILFYEIYTKA-GLPYDGW
     |||. ...                      ...|||..||  ||.||.|||.|.         ..||.. .|||. |.| .||.| . . .| |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SNQRVWV-----------------------EVSAGYRLPCPESCS--------------KAVYDLMLACWDETPGFRPSFGKLAEQL
|||.||.                       ||  ..|.|.|. |.              ...||||. ||.. |  ||.|  | |||
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKC5.AA UTK 1780-2036 37 5.5e-113 381.66 In-house 1-296 (296) Show / Hide 
Range on Protein: 1780-2036
Range on HMM: 1-296/296
Sequence Identity: 37% (111 aa)

LTMLEELGRGAFGLVYKALFEESPNPGFL--VAVKSLH-HTAGVSDRQ---ELLEEAA---VMVQLD-HPNVVKLVGVVTVGEPLLVVLEYCEKGSLKSY
.  ...||.|||| |.|| |.. .... .  |||| .  | ..  ..    ...|||.   .| |.. ||||..||||.| .||...|.||.|.|.| ||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LENNPD--------VSESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDAL-------MRCRIADFG---LAREEN-------DGADAYYRSR-SGN
| ....        ... |.. .. .|. ||...|...||||||||||.|...        | |.|||||   ..|. |       .. . ||...  . 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPVRWTAPEALDER-KFSESTDVWAAGILFYEIYTKAGLPYDGWSNQRVWVEVSAG--YRLPCPESCSKAVYDLMLACWDETPGFRPSFGKLAEQL
.|.||.|||||... .|....|||. |.. .||.| . ||| |.||..||..|..|  ||.|||..|. .||.||..||  .| .||.|  | .|.
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RTKC5.AA RTKD 1780-2038 42 1.3e-105 357.14 In-house 1-262 (262) Show / Hide 
Range on Protein: 1780-2038
Range on HMM: 1-262/262
Sequence Identity: 42% (112 aa)

LTMLEELGRGAFGLVYKALFEE---SPNPGFLVAVKSLHHTAGVSDRQELLEEAAVMVQLDHPNVVKLVGVVTVGEPLLVVLEYCEKGSLKSYLENN-PD
...|| .| | .| | ||. ||   .  |||||||| .  ..  .   |.. ||| | |. |.|.| | ||||. .|   | |||| ||| .||  |  |
IKCLEPIGKGNWGMVFKAMLEEHIMKGIPGFLVAVKIM-KNQSQEQVMEMTREAAFMAQFNHDNIVRLHGVVTTNQPHIMVMEYCEHGSLQAYLRENGED

VSESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDALMRCRIADFGLAREENDGADAYYRSRSGNLPVRWTAPEALDERKFSESTDVWAAGILFYEI
.  .. .|.   .  | . .| .  .||| ||||.||| ..|  |.|||| | . .|  .|| |. .  |||| |||.| | |||   |||  ... |||
MDNQHRFRMARDVAMGLAYLHFRGCCHRDIAARNILLDSNYRAKIGDFGLTRQQANGDSEYYISHGQAIPVRWCAPEVLEEHKFSQASDVWSWAVFVYEI

YTKAGLPYDGWSNQRVWVEVSAGYRLPCPESCSKAVYDLMLACWDETPGFRPSFGKLAEQLSD
 |.| |||.. .||.||  | .||||. |. |......||  || | |  ||.. .. .|. .
WTQAQLPYRDMHNQKVWHYVIQGYRLTRPMQCPRDIWALMMDCWAEDPKERPRMCQVVDQMTK
Kinase RTKC5.AA Src 1780-2036 37 2.6e-89 303.03 In-house 1-255 (255) Show / Hide 
Range on Protein: 1780-2036
Range on HMM: 1-255/255
Sequence Identity: 37% (97 aa)

LTMLEELGRGAFGLVYKALFEESPNPGFLVAVKSLHHTAGVSDRQELLEEAAVMVQLDHPNVVKLVGVVTVGEPLLVVLEYCEKGSLKSYLE---NNPDV
......||.| || |.....  .      ||||.|       . . .|.|| .| .|.|...|.|  |.. .|| . | || ..|||  ||        .
IKLCRKLGQGQFGEVWMGYWNGN----TKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHL

SESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDALMRCRIADFGLAREENDGADAYYRSRSGNLPVRWTAPEALDERKFSESTDVWAAGILFYEIY
.  | | .  |.. ||. . ..|..|||||||||| .    | .|||||||   .. | |  .   ..|..||||||.....|.  .|||  ||| .|| 
HLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIV

TKAGLPYDGWSNQRVWVEVSAGYRLPCPESCSKAVYD-LMLACWDETPGFRPSFGKLAEQL
|.   || |..|. |  .|..|||.|||. | . .|. .|| ||...|  || |  | . |
TYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase RTKC5.AA Fer 1780-2037 34 3.5e-89 302.6 In-house 1-283 (283) Show / Hide 
Range on Protein: 1780-2037
Range on HMM: 1-283/283
Sequence Identity: 34% (97 aa)

LTMLEELGRGAFGLVYKA------LFEESPN-PGFLVAVKSLHHT-AGVSDRQELLEEAAVMVQ-LDHPNVVKLVGVVTVGEPLLVVLEYCEKGSLKSYL
 |. . ||.|||| |||.      . . . . .   |.|| .. . |.   ..|.. || .| . .|||||||. || .  .|...|.|.|  |||.|||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

ENNPD--VSESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDA-LMR--CRIADFGLAREENDGADAYYRS-RSGNLPVRWTAPEALDERKFSESTD
  |..  ||. .|||.| |.. |||..|.|| .|||.||||.|...      | |.|||..|.. |.  .|.    .  .|.||.|||... . .|. ||
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWAAGILFYEIYTKAGLPYDG---------WSNQRVWVEVSAGYRLPCPESCSKAVYDLML-ACWDETPGFRPSFGKLAEQLS
||. |.. .||.|..  || |         . .|.. . . .||..|.|... .... .|.  ||.. |  ||.. .. ..| 
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase RTKC5.AA Eph 1780-2036 38 2.2e-81 273.13 In-house 1-264 (264) Show / Hide 
Range on Protein: 1780-2036
Range on HMM: 1-264/264
Sequence Identity: 38% (101 aa)

LTMLEELGRGAFGLVYKALFEES-PNPGF---LVAVKSLHHTAGVSDRQELLEEAAVMVQLDHPNVVKLVGVVTVGEPLLVVLEYCEKGSLKSYL-ENNP
... . .| | || |..     . .       .||.| |  ..  ..| . | ||..| | ||||...| |||| ..|. .| || | ||| |.| ..  
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

DVSESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDALMRCRIADFGLARE-ENDG-ADAYYRSRSGNLPVRWTAPEALDERKFSESTDVWAAGILF
 ..  | .   . |  ||    . |.|||||||||.|...  .| ..|||| |. |.|. ..| | .|.|  |.|||||||.  |||. . |||  ||. 
QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVM

YEIYTKAGLPYDGWSNQRVWVEVSAGYRLPCPESCSKAVYDLMLACWDETPGFRPSFGKLAEQL
 |. .    ||  .||| |  ..  ||||| |  | .| . ||| ||   .  || | ..   |
WEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase RTKC5.AA TK-Unique 1780-2036 33 1.4e-80 274.0 In-house 1-294 (294) Show / Hide 
Range on Protein: 1780-2036
Range on HMM: 1-294/294
Sequence Identity: 33% (100 aa)

LTMLEELGRGAFGLVYKALFEE--SPNPGF-LVAVKSLHHTAGVSDRQELLEEAAVMVQLD-HPNVVKLVGVVT-VGEPLLVVLEYCEKGSLKSYLENNP
|......|.|||| |... ...   ..  .  |||| |.  |   |.|..| |...| .|. |||.|...|. |  .|| . ..|||..|.| .|| .. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

D--------------------------VSESQKIRFCKQISLGMEHIHE--KNFVHRDLAARNVLLDALMRCRIADFGLAREENDGADAYYRSRS-GNLP
.                          .|. . ..|..||  |||....  |..|||||.||||||    .| |.|||.||....   .| ...| | .|
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRIP

VRWTAPEALD--ERKF-SESTDVWAAGILFYEIYTKAGLPYDGWSNQRVWVEVSAGYRLPCPESC-SKAVYDLMLACWDETPGFRPSFGKLAEQL
.|| |||.|   .. . .. .|||. |.| .|| |  . || | .. ..  .. .|||.| ||.| |...| ||  || . |  |||| ... .|
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RTKC5.AA Frk 1780-2040 38 1.4e-71 244.1 In-house 1-260 (260) Show / Hide 
Range on Protein: 1780-2040
Range on HMM: 1-260/260
Sequence Identity: 38% (103 aa)

LTMLEELGRGAFGLVYKALFEESPNPGFLVAVKSLHHTAGVSDRQELLEEAAVMVQLDHPNVVKLVGVVTVGEPLLVVLEYCEKGSLKSYLE----NNPD
. .. .|| | || |.  |.    |    |||| |   .|  | ...| || .| .| || ...|  | || ||.... |  ..|||. ||     .   
IQLIRRLGSGQFGEVWEGLW----NNTTPVAVKTLK--PGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQ

VSESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDALMRCRIADFGLAR-EENDGADAYYRSRSGNLPVRWTAPEALDERKFSESTDVWAAGILFYE
.   | .    |.  ||  . ..|..||||||||||..    |.||||||||    |  | |       .|..||||||    ||.   |||. ||| .|
CQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTE

IYTKAGLPYDGWSNQRVWVEVSAGYRLPCPESCSKAVYDLMLACWDETPGFRPSFGKLAEQLSDLI
| |   .|| |  |. |   |..|||.|.|  | . .|..|| || . |  || |  |  .| | .
IITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase RTKC5.AA S_TKc 1780-2040 23 9e-55 189.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 1780-2040
Range on HMM: 1-231/231
Sequence Identity: 23% (65 aa)

LTMLEELGRGAFGLVYKALFEESPNPGFLVAVKSLHHTAGVSDRQELLEEAAVMVQLDHPNVVKLVGVVTVGEPLLVVLEYCEK--GSLKSYLENNPD--
 ..|...|.|||| |||.   .    | .||.| ..        . .. | ... . .|||.||| .|    . | .|.|||.   |.|..|.....   
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----VSESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDALMRCRIADFGLAREENDGADAYYRSRSGNLPVRWTAPEALDERKFSE-STDVWAAGI
     .| .  ....|| ...|..|.....||||   |.|||   .  |.||||||.           ..      . ||| |   ...  . |.|. |.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LFYEIYTKAGLPYDGWSNQRVWVEVSAGYRLPCPESCSKAVYDLMLACWDETPGFRPSFGKLAE-----QLSDLI
..|| ..    |..   .. .  ..            |. . |..  |..  |  ||.  .. .      .   .
ILYEMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKC5.AA CTKA 1887-2036 42 1.1e-49 165.0 In-house 139-290 (290) Show / Hide 
Range on Protein: 1887-2036
Range on HMM: 139-290/290
Sequence Identity: 42% (64 aa)

QISLGMEHIHEKNFVHRDLAARNVLLDALMRCRIADFGLAREENDGADAYYRSRSGNLPVRWTAPEALDERKFSESTDVWAAGILFYEIYTKAGLPYDGW
||  ||.   |  |||||||.||.||       |||||..|    ..  || | .. .|||| ||||| . |||   |||| |.| .|| . . .|. . 
QIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHM

SNQRVWVEVSAG--YRLPCPESCSKAVYDLMLACWDETPGFRPSFGKLAEQL
| | |   . ..   ||| | .|   .| .|  ||   |  ||.|  | . |
SDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase RTKC5.AA Pkinase 1780-2040 23 5e-42 149.67 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1780-2040
Range on HMM: 1-293/293
Sequence Identity: 23% (71 aa)

LTMLEELGRGAFGLVYKALFEESPNPGFLVAVKSLHHTAGVSDRQELLE---EAAVMVQLDHPNVVKLVGVVTVGEPLLVVLEYCEKG----SLKSYLE-
.. .. .|.|.|| |||.    ..    .|||| .      |. .. .    |...|  |.|||.|.| .... .  . .|.||||.|    .|..|.. 
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-NNPDV--SESQKIRFCKQISLGMEHIHEKNFVHRDLAARNVLLDALMRC----RIADFGLARE-ENDGADAYYRSRSGNLPVRWTAPEALD-ERKFSES
 ..  .  || . .....||  |.|..|.....||||   |.|.|  . .    .|.|||||.  .    .  . .. | .  .. ||| .   .. . .
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTP--WYMAPEVIRGGQYYGPK

TDVWAAGILFYEIYTKAGLPYDGW-------SNQRVWVEVSAGYRLPCPESCS-------------------KAVYDLMLACWDETPGFRPSFGKLAEQL
 |.|..|...|| ...  .|..|         .|..    .. .. ..|..||                   ..  |..  |..  |  ||.    |||.
VDMWSCGCILYEMLCGR-PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQI

SDL--I
     .
LQHPWF
Kinase RTKC5.AA CTKA 1780-1870 33 5.9e-23 73.84 In-house 1-100 (290) Show / Hide 
Range on Protein: 1780-1870
Range on HMM: 1-100/290
Sequence Identity: 33% (33 aa)

LTMLEELGRGAFGLVYKALFEESPN-------PGFLVAVKSLHHTAGVSDRQELLEEAAVMV--QLDHPNVVKLVGVVTVGEPLLVVLEYCEKGSLKSYL
.    ..| | .| |..|.    |         | .||||.|   |   ||.. | || |    ...||||. |.||.|  .|.. . |.   | |..||
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYL
CAP_GLY RTKC5.AA CAP_GLY 2090-2135 36 1.5e-11 42.37 Pfam 1-50 (72) Show / Hide 
Range on Protein: 2090-2135
Range on HMM: 1-50/72
Sequence Identity: 36% (18 aa)

VGQRVYV--EGYNTMGTLMFYGPHQSKAG-LRAGVVL-DKPIGNNDGTVG
||.|. |  .| .  ||....|| ..... . .|| . |.| |.|||.|.
VGDRCEVWDGGGGRRGTVRYVGPTPGFKPGTWVGVEWDDEPRGKNDGSVQ