Gene 10525 (M.brevicollis)

10525

Species: M.brevicollis
Alias: 10525
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
10525.AA Protein None 832 None Fasta, JSON

Protein domain

Protein domains of 10525.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 10525.AA SH2 39-126 23 1.4e-05 25.23 SMART 1-87 (87) Show / Hide 
Range on Protein: 39-126
Range on HMM: 1-87/87
Sequence Identity: 23% (21 aa)

IPYFHGALPKDICDASLAKMGMKDGTYMLRLYKPNDPSILVLTVVYKGKPTHHQVQHEA-TVWSINRKVLPGCTSVRRLVAALAVTHAD
 |..|| .... ... | . ||.||....|   . .|  .||.| .|||  | ......   ..|     . . |.  ||.    .   
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 10525.AA SH2 41-98 22 0.028349 8.5 Pfam 1-60 (81) Show / Hide 
Range on Protein: 41-98
Range on HMM: 1-60/81
Sequence Identity: 22% (14 aa)

YFHGALPKDICDASLAKMGMKDGTYMLRLYKPNDPSILVLTVVYKG---KPTHHQVQHEAT
..|| ...      | . |..|||...|      |   .|.|...|   . .| ..| ...
WYHGKISRQEAERLLMNPGNPDGTFLVRESES-TPGDYTLSVRDDGPGDRVKHYRIQRTDN
SH2 10525.AA SH2 417-442 39 8e-06 18.86 Pfam 1-28 (81) Show / Hide 
Range on Protein: 417-442
Range on HMM: 1-28/81
Sequence Identity: 39% (11 aa)

YYHGDITPAQAEAALNA--AKDGQYLLR
.|||.|. ..||  |..   .|| .|.|
WYHGKISRQEAERLLMNPGNPDGTFLVR
SH2 10525.AA SH2 415-502 20 2.8e-05 21.94 SMART 1-87 (87) Show / Hide 
Range on Protein: 415-502
Range on HMM: 1-87/87
Sequence Identity: 20% (19 aa)

TLYYHGDITPAQAEAALNA--AKDGQYLLRAHEASRHAFAVILSHVHNGSILHTPLTQSDLNGSFKIGQ-VATGERNLNDALRFLHAQQPG
  .|||.|. ..||. |..   .|| .|.|  | .. .... . .   | . |  . ..|  |.. |..   .   .| . ... .    |
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK--GKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG