Gene N8 (M.brevicollis)
N8
Species: M.brevicollis
Alias: N8
External Links:
Annotation:
Sequence
Protein domains of N8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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MYSc | N8.AA | MYSc | 12-716 | 35 | 2.4e-263 | 882.06 | SMART | 1-771 (771) | Show / Hide |
Range on Protein: 12-716 Range on HMM: 1-771/771 Sequence Identity: 35% (278 aa) VAPGQC---DNLTALADLNEDTLLKELEIRYNRDVIYTYVGEILVAVNPYFRIPELYDQSQKLKYR-----GGIDRESLPPHIFAVADAAVSALQSTGKN . | .. | .. | .|||...| |..||..| |||| | ...||||| ..|..| ... .|| | |. .||||||.||.| .. . ..| MNPPKFEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKEN QVCVISGESGAGKTESAKLFLQHIIDLSAGSETEGIADKIIAVNPLLEAFGNASTLMNDNSSRFGKYLDLQFTENFTVRGALITEYLLEKSRVTYQADGE | ..|||||||||||..|. .|.. .|. ..|.. ..|.. ||.||||||| |. |.|||||||| ...| |. ...|| |. ||||||||.||..|| QCIIISGESGAGKTENTKKIMQYLAAVSG--QVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNKGE QNFHIFYYIFAGLDASAKAQYELG----SAEDHGYINGNA---------EALAFIGTKECRDMWQE----VSACFDLVGFSQGEKDNLFAILSGVLWLGD |.||||.. ||... | .. |. ..|| |.| .. . . . . ..| . .. .||| |... | |....|.|| RNYHIFYQLCAGASEEQKQEFHLKPFSHNPEDYHYLNQGGHYWNNKRHQSQCFTVDGIDDAEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAAILHLGN VLFDGE----DHASI----VSPSSILEAACNQLGLEVGVMEAALVEQILITGGE---ETTKALRTDQAVDVRDATAKALYGRAFTWIIKRVNSLTGPKGR . | . | ... |. .|..|| ||... ..| .|. .. ||.| . ||.| ||.. ||| |||.|.| | ||.||.|. IEFEQGRNQYDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRINQSM----- GTGQIISFLDIFGFEHFDDNSLEQLCINLANEQLQSFFNSHIFQMELDEYKKEGIDGSQVSFT--DNQATLDMLLSR--RPPGILAIMDEQAIM---PRS . |. |||.|||.|. ||.||.||| .||.|| ||| |.| .| .||..|||. . . |. |||...| . . ||.||....||. . |.. -HNYFIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFMYDNQPCCDLIEKKGKRPMGIFSLLDEECMFHAQPKG TDQTMVEKF-----HETFGSHSSYIKP-----------RSNDAIFTIRHYAGDVCYNADGFLEKNRDTLAMDVLGALRMSENSLVRELFDGDADDAKAAK ||||..|| | ....|. . || | .. |.|.||||||.||..|.||||.||| |.. .. | |.....||. ..|...... TDQTFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEYEDQTSQTP GKRGKRGGGRGLSRNNMRMSVKK--ARAAEAKKQRKSVGATFKESLEKLMTSLNSSAPHFIRCIKPNQSKQKHMYADQLVKNQLRYTGMLETTRIRKEGY ..... .|.....|.. | . . || ..||. || .|..||. |||. ||.||||||| |. . . |.||..|||. |.||. |||..|. QEKSS-QGKNKSRRKKR-M-MQMKKT-C-MQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEEKKPWDFDDDLVLHQLRCCGVLENIRIRRAGF AVRPTFEDFLHRYMPLTF-AWGIGQ--------SANAGACRMLLEKAK---------LKDWQIGKTKVFLR-YYHPDELNDLVKP ..| ....|..|| | . | .. . ||...|.. . ...|.||||||.| ... .| .. . PYRWPYQEFYQRYKMLCPPTWPNWGNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDMYQFGKTKVFFRNPGQLFHLEEMRER |
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Myosin_head | N8.AA | Myosin_head | 17-703 | 32 | 3e-231 | 779.3 | Pfam | 1-765 (765) | Show / Hide |
Range on Protein: 17-703 Range on HMM: 1-765/765 Sequence Identity: 32% (258 aa) CDNLTALADLNEDTLLKELEIRYN-RDVIYTYVGEILVAVNPYFRIPELYDQSQKLKYRGGIDRESLPPHIFAVADAAVSALQSTGKNQVCVISGESGAG .....| |||...| |. ||. | ||||.| ....|||| ..| .| |. .||| |. .||||||.||.| .. . ..|| ..|.|||||| VEDMVMLTYLNEPSVLHNLKKRYMTGDLIYTYSGHFCISVNPYKQLP-IYTQDMIQEYRGKH-RYEMPPHIFAIADEAYRHMRHDRENQCIIICGESGAG KTESAKLFLQHIIDLSAGSE---TEGIADKIIAVNPLLEAFGNASTLMNDNSSRFGKYLDLQFTENFTV----RGALITEYLLEKSRVTYQADGEQNFHI |||..|. .|.. .|.... . . ..|.. ||.||||||| |. |.||||||||. ..|.. .. |. |. ||||||||.||. || |||| KTENTKYVMQYFASVSGSNPGVNMGRVEQQILQSNPILEAFGNAKTTRNNNSSRFGKYMEIHFDKTGKINPTAVGGNIENYLLEKSRVVYQTPGERNFHI FYYIFAGLDASA-KAQYELG--SAEDHGYINGNA-EALAFI-GTKECRDMWQEVSACFDLVGFSQGEKDNLFAILSGVLWLGDVL-FDGED--HASIVSP ||.. ||..... |. . |. ...| | | .. .. . .. |.. .|..||.. |. .| |....| || . | .. ...|. FYQLLAGASQQEEKKELHLTSADPKDYHYLNQSGTNPCYTVDDGIDDAEEFQHTRNAMDIIGFTHEEQRSIFRIVAAILHLGNMKGFKQDQNEEQAVVDD SS-ILEAACNQLGLEVGVMEAALVEQILITG----GEETTKALRTDQAVDVRDATAKALYGRAFTWIIKRVNSLTGPKG--------------------- . |.|..| .|. ....|..|.. .. || | ||.. ..|| . ||| |||.|.| | ||..|.| | TEEICEIICELMGVDPEEFEKWLCYRRIKTGGGKRREWVTKPQNCEQAMYARDALAKAIYSRMFDWIVNRINQAICHKTQNTDDSDGQAAQWDDTVSITV --------RGTGQIISFLDIFGFEHF-DDNSLEQLCINLANEQLQSFFNSHIFQMELDEYKKEGIDGSQVSF-TDNQATLDMLLSR-RPPGILAIMDEQA . .. .| |||.|||.| . ||.||.||| .||.|| ||| |.|. | .||..|||. ... . .|||.. | |. .|.|||...||. VDVPDPAFDKRNYFIGVLDIYGFEIFCEKNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYVREGIQWTFIDYGFDNQPCCD-LIEKKKPMGILSLLDEEC IMPRSTDQTMVEKFHETF-GSHS--SY-IKP-R------SNDAIFTIRHYAGDVCYNADGFLEKNRDTLAMDVLGALRMSEN-SLVRELFDG-------- ..|..||||...| ..|. . |. . || | .. |.|.||||||.||..|.||||.|.| |...... | . ....|||. WFPKATDQTFLQKLYQTHSSKHPRLHFAQKPGRFYKRHRQGNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDDLIELMWCSWDNPFMQELFPDWEWAEWAH ---------DADDAKAAKGKRGKRGGGRGLSRNNMRMSVKKARAAEAKKQRKSVGATFKESLEKLMTSLNSS---APHFIRCIKPNQSKQKHMYADQLVK . ...|.. ...|. |..| . ..| . |.. |||.. .||. |.. ||..|||||| || .. ...|. MQIDFEADFHEEEFKRRYNRNGCQKGKQGKKKWFM----------------QTVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNENKQPWQFDNSMVL NQLRYTGMLE-TTRIRKEGYAVRPTFEDFLHRYMPLTF-AWGIG-----QSANAGACRMLLEKA---KL--KDWQIGKTKVFLR .|||. |.|| . ||. .|.. |.|. .|..|| |.. .|... . .|...|.. .. ...|.||||.|.| HQLRCNGVLEINIRICRAGFPYRWTYDEFFQRYRILCPKTWWSWIWPEWNGDTKQGCEKILQHLSWGNMDKEEYQFGKTKIFFR |
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SH2 | N8.AA | SH2 | 843-918 | 41 | 1.7e-30 | 91.39 | Pfam | 1-81 (81) | Show / Hide |
Range on Protein: 843-918 Range on HMM: 1-81/81 Sequence Identity: 41% (34 aa) WFHGVVSRVHSESLLGK--QPVGTFLIRVAETRF-GYSLSVRTPA---RIKHFMIDQSPDGQYMVVGNDRLFPSLNDLVTHY |.|| .|| | || . .| ||||.| |. .|.||||. |.||. | . ..|.| . |... |.||..|| || WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK-FCSLQELVEHY |
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SH2 | N8.AA | SH2 | 841-924 | 42 | 8.8e-27 | 96.21 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 841-924 Range on HMM: 1-87/87 Sequence Identity: 42% (37 aa) AKWFHGVVSRVHSESLLGK--QPVGTFLIRVAET-RFGYSLSVRTPARIKHFMIDQSPDGQYMVVG-NDRLFPSLNDLVTHYRHSPLT |.|| .|| |.|| . .| |.||.| |. . .|.||||. ..||. | ...||.| . . ..| |||| .|| ||.| || QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG |