Gene 34161 (M.brevicollis)

34161

Species: M.brevicollis
Alias: 34161
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Myo-SH2

Sequence

Name Sequence Type Origin Length Description Download
34161.AA Protein None 947 None Fasta, JSON

Protein domain

Protein domains of 34161.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
MYSc 34161.AA MYSc 3-689 33 7.89999999999e-211 707.61 SMART 1-771 (771) Show / Hide 
Range on Protein: 3-689
Range on HMM: 1-771/771
Sequence Identity: 33% (261 aa)

GSGTTAVGAVDDLATLTTLDNDLLLEHLHQRYEKDVIYTYVGDILIAINPFKEL-GIYDAAHKAEYQ-----QGNPKLQHTPHIFAVADTAYHDMLKTGK
   .  .| |||...|| | .. .|..|..||..| |||| |...||.||.|.| .||   . ..|.     .|. .    |||||.|| ||..||. ..
MNPPKFEG-VDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKE

DQCCVISGESGAGKTESAKFVISHIIDLCRAGDLGSKLEQRILQMNPLLEAFGNASTFLNDNSSRFGKYTELLFNPQGQVMGARLSEYLLEKSRVVHQMV
.||..|||||||||||..|... ..  ..     .. .||.||| ||.||||||| |  |.|||||||| |. |.  | . ||  . |||||||||.|  
NQCIIISGESGAGKTENTKKIMQYLAAVSG---QVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNK

EDKNFHVFYYLFAS---AERDLLGLDT----PATFPYLNQG----------------SIPSDAHQQLEL---VHQALDDIGFTREEQSMLQHVLAAVLHT
 . |.|.||.| |    .... ..|..    |  . |||||                .. .||.   |    ...|.. .||. |||     ..||.|| 
GERNYHIFYQLCAGASEEQKQEFHLKPFSHNPEDYHYLNQGGHYWNNKRHQSQCFTVDGIDDAEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAAILHL

GRINFKSADH-LEPAHFAD---GAEGVLAQVAKLLKVDQAALHEALMASNVITRGE---AIRKPFTLEQAEDTRDAMAKALYGRMFGWIVSGINGLLKPD
| | |.. ..  . .. ..    .| .|  ...||.||.. | ..|    . |..|    |.|| ..|||...|||.|||.|.|.|.|||. ||  ..  
GNIEFEQGRNQYDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRINQSMHNY

LPGILDIFGFEIHAESGFEQFCINLANEQLQHFFN-------QQEYARQGVDGANVTYV--DNGPVLDMFLSR---PVGLLALLDEESHF---PKATDET
  |.|||.||||    .||||||| .||.|| |||       |.|| | |..  .. ..  || |..|    .   | |...|||||. |   ||.||.|
FIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFMYDNQPCCDLIEKKGKRPMGIFSLLDEECMFHAQPKGTDQT

LVLKF-----ALQFKDYKAFVPA-----------QGADCSFTVRHYAEDVQYTGYGFLYKNRDSMAPDVSAVLQTSGLSVVAESFLAEVSSTGQILADRA
.. |       ...|. . |...             .. .|...||| ||.|   |.| ||.|   .|. ...|.|  ..... |  ....|.|   .. 
FLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEYEDQTSQTPQEKS

RWGANAGRRRQKDYMPGAGKKTMNTTNKRALTVSGQFRNSLFLLVEKMTACSPHFVRCIKPSKTKNANFFDPSYVMAQLKYTGMLETTRIRREGYSFRPS
. ... . || |  | .. |||. .  ||  ||. ||. .|  |.|.. .|.||..|||||  .| .. ||.. |. ||.. |.||. ||||.|...| .
S-QGKNKSRRKKR-MMQM-KKTC-MQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEEKKPWDFDDDLVLHQLRCCGVLENIRIRRAGFPYRWP

FEEFLERRTKVFLKYFQA-----------EALDEKVQQFQKHA-------ASLQKVAKG----FLA-RRHVQQMNEQKRK
..||..|  .   .  ..            . .  .. .|..           .... |    |.   ....   |. ..
YQEFYQRYKMLCPPTWPNWGNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDMYQFGKTKVFFRNPGQLFHLEEMRER
Myosin_head 34161.AA Myosin_head 12-517 36 3.7e-161 546.48 Pfam 1-587 (765) Show / Hide 
Range on Protein: 12-517
Range on HMM: 1-587/765
Sequence Identity: 36% (214 aa)

VDDLATLTTLDNDLLLEHLHQRYE-KDVIYTYVGDILIAINPFKELGIYDAAHKAEYQQGNPKLQHTP-HIFAVADTAYHDMLKTGKDQCCVISGESGAG
|.|.. || | .. .|..|..||  .| ||||.|...|..||.|.| ||   . .||   ... . .| ||||.|| || .|.  ...||..|.||||||
VEDMVMLTYLNEPSVLHNLKKRYMTGDLIYTYSGHFCISVNPYKQLPIYTQDMIQEY--RGKHRYEMPPHIFAIADEAYRHMRHDRENQCIIICGESGAG

KTESAKFVISHIIDLCRAGD--LGSKLEQRILQMNPLLEAFGNASTFLNDNSSRFGKYTELLFNPQGQV----MGARLSEYLLEKSRVVHQMVEDKNFHV
|||..| |....  ..  .    .. .|| ||| ||.||||||| |  |.|||||||| |. |.  |..     |.. . |||||||||.|  .  |||.
KTENTKYVMQYFASVSGSNPGVNMGRVEQQILQSNPILEAFGNAKTTRNNNSSRFGKYMEIHFDKTGKINPTAVGGNIENYLLEKSRVVYQTPGERNFHI

FYYLFASAERDL----LGLD-T-PATFPYLNQ-G-----SI--PSDAHQQLELVHQALDDIGFTREEQSMLQHVLAAVLHTGRIN-FKSADHLEPAHFAD
||.| |.|   .    |.|. . |  . |||| |      .  . |  .  . . .|.| ||||.|||  . ...||.|| | .  ||. .  | |   |
FYQLLAGASQQEEKKELHLTSADPKDYHYLNQSGTNPCYTVDDGIDDAEEFQHTRNAMDIIGFTHEEQRSIFRIVAAILHLGNMKGFKQDQNEEQA-VVD

GAEGVLAQVAKLLKVDQAALHEALMASNVITR----GEAIRKPFTLEQAEDTRDAMAKALYGRMFGWIVSGINGLLKPDL--------------------
. |  .  .. |..||.. .  .|.   . |.     | . || . ||| . |||.|||.|.||| |||. ||  ..  .                    
DTEEICEIICELMGVDPEEFEKWLCYRRIKTGGGKRREWVTKPQNCEQAMYARDALAKAIYSRMFDWIVNRINQAICHKTQNTDDSDGQAAQWDDTVSIT

---------------PGILDIFGFEIH-AESGFEQFCINLANEQLQHFFN-------QQEYARQGVDGANVTY-VDNGPVLDMFLS-RPVGLLALLDEES
                |.|||.||||     .||||||| .||.|| |||       |.|| | |..  .. |  || |. |   . .|.|.|.|||||.
VVDVPDPAFDKRNYFIGVLDIYGFEIFCEKNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYVREGIQWTFIDYGFDNQPCCDLIEKKKPMGILSLLDEEC

HFPKATDETLVLKFALQF-KDYK--AF-VPA-------QGADCSFTVRHYAEDVQYTGYGFLYKNRDSMAPDVSAVLQTSGL-SVVAESF
 ||||||.|.. |   ..        | .         .. . .|...||| || |   |.| ||.|   .|...... |   . ..| |
WFPKATDQTFLQKLYQTHSSKHPRLHFAQKPGRFYKRHRQGNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDDLIELMWCSWDNPFMQELF
Myosin_head 34161.AA Myosin_head 564-639 40 7.2e-29 99.29 Pfam 634-713 (765) Show / Hide 
Range on Protein: 564-639
Range on HMM: 634-713/765
Sequence Identity: 40% (32 aa)

TVSGQFRNSLFLLVEKMTAC---SPHFVRCIKPSKTKNANFFDPSYVMAQLKYTGMLE-TTRIRREGYSFRPSFEEFLER
||. ||....  |.. ...|   .||.||||||   | .. ||.| |. ||.. |.|| . ||.|.|...|. . ||..|
TVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNENKQPWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQR
SH2 34161.AA SH2 839-916 42 5.4e-26 78.14 Pfam 1-81 (81) Show / Hide 
Range on Protein: 839-916
Range on HMM: 1-81/81
Sequence Identity: 42% (36 aa)

WFHGVITRREAEDLLAP--KPIGCFLTRISETRL-GYTLSVRTRH---ACKHFVIEETRESPSRYMLQGRDVYFDTLERLIEHY
|.|| |.| |||.||    .| | || | ||.   .||||||.       ||..| .| .    | . ||.  |..|  |.|||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNG--GYYITGRHK-FCSLQELVEHY
SH2 34161.AA SH2 837-922 35 6.5e-25 90.0 SMART 1-87 (87) Show / Hide 
Range on Protein: 837-922
Range on HMM: 1-87/87
Sequence Identity: 35% (32 aa)

HDWFHGVITRREAEDLLAP--KPIGCFLTRISET-RLGYTLSVRTRHACKHFVIEETRESPSRYMLQG-RDVYFDTLERLIEHYRGHPAN
. |.|| |.| |||.||    .| |.|| | ||. . .|.||||..  .||..|... .  ..| ...  ...|..|  |..||. .|  
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD--GKYYIDETWRRKFPSL-ELVNHYQHNPLG