Gene 34112 (M.brevicollis)

34112

Species: M.brevicollis
Alias: 34112
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: SH2-R

Sequence

Name Sequence Type Origin Length Description Download
34112.AA Protein None 1630 None Fasta, JSON

Protein domain

Protein domains of 34112.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
VWA 34112.AA VWA 259-444 28 3.1e-43 142.94 Pfam 1-190 (190) Show / Hide 
Range on Protein: 259-444
Range on HMM: 1-190/190
Sequence Identity: 28% (58 aa)

DLVFLLDGSNSVSEPD-WIRTKQFVVDMIE-YFNVNTTYSTIGTRVGLAWYSTNVSKEFDLDTYDSSEEAQCAV-QRTKREIGETY-TGKALTYVEENMF
|.||..|||.|..| . . ..|.|.....|  ..     .  ||||||  ||..|  ||.|..| | .. . || .. .   | |. ||||| |. ...|
DIVFVIDGSGSMGEQNRFEKVKDFIKNFVEKNLD----IGPDGTRVGLVQYSDDVRTEFPLNDYQSKDDVLQAVNRNMYYMGGGTNNTGKALQYAYQHLF

AA--QYGMRTTMDIEHYLVLISDGKSTDD--IVLPARDLRDN----GITIFTIGIISSSTSSSDAAAQRLELRTIA--G-SEDRFFEIESIQFVS--EVV
    . |.|   .. . .....||.|.|.  .  ||  |||.    ||..|..|.        .  . . |||.||  . .|...| ... .  .  ...
HSMRSAGSRP-ENVPKVIIVFTDGYSQDGPDVP-PAAKLRDKKKGVGIYVFGVGVG-------GGNVDEEELRQIASCPCNEGHVFCVTDFDDLWLQDIQ

DSL
. .
EQM
VWA 34112.AA VWA 257-445 25 4.5e-32 113.8 SMART 1-193 (193) Show / Hide 
Range on Protein: 257-445
Range on HMM: 1-193/193
Sequence Identity: 25% (55 aa)

HIDLVFLLDGSNSVSEPDWIRTKQFVVDMIEYFNVNTTYSTIGTRVGLAWYSTNVSKEFDLDTYDSSEEAQCAVQRTKR-------EIGETYTGKALTYV
  |.||..|||.|... .. ..|||. ...| ..        |.|||.  .|..|  ||.|. | . .... |... ..         | |.|| || |.
WLDIVFVIDGSGSMGPNNFQQVKQFI-KFVEQLD--------GDRVGIVQFSDDVRVEFPLN-YQDKDDVLKAIDNLQYKGKHDYFMGGGTNTG-ALQYA

EENMFAAQYGMRTTM-------DIEHYLVLISDGKSTD------DIVLPARDLRDNGITIFTIGIISSSTSSSDAAAQRLELRTIAGSEDRFF-------
 .| |... | |          .. . .....||.|.|      ||  .||.||..|..||.||. ..          . |||.||.   ...       
MQNLFHERQG-RRGAGRPTKFWNVPKVIIVFTDGYSNDGPHDPEDIRKAARELRRSGVKIFVIGVGND---------DM-ELRQIASCP-GEHHFFDVYD

EIESIQFVSEVVDSLR
 ... . . ...|.| 
YDDLPDIFQHIIDWLC
SH2 34112.AA SH2 915-962 26 0.067703 7.39 Pfam 39-81 (81) Show / Hide 
Range on Protein: 915-962
Range on HMM: 39-81/81
Sequence Identity: 26% (14 aa)

IAVRERR---RVRHVAIEVSDDA-YFLDPKMSDDYPFQQPRFGYLPDLVAHY
. ||      ||.|  |   |.  |..         .  ..|. |..|| ||
LSVRDDGPGDRVKHYRIQRTDNGGYYI---------TGRHKFCSLQELVEHY
SH2 34112.AA SH2 1238-1262 40 5.9e-05 16.37 Pfam 1-27 (81) Show / Hide 
Range on Protein: 1238-1262
Range on HMM: 1-27/81
Sequence Identity: 40% (11 aa)

WYQPTIVRWEATEMLRH--QPEGSFVV
|| . | |.|| ..|.   .|.|.|.|
WYHGKISRQEAERLLMNPGNPDGTFLV
SH2 34112.AA SH2 1515-1606 26 3.4e-14 54.42 SMART 1-87 (87) Show / Hide 
Range on Protein: 1515-1606
Range on HMM: 1-87/87
Sequence Identity: 26% (25 aa)

DPWLHRDLSREQADRILRSAAHDLSRSEGEGIYLVRTSEKAQNAYVVSLMSGGAPHHYLFREAE-GGFVLKG---KFFRATCVRDLLNLFKEDDDV
 || | ..|||.|...|..       .  .| .||| ||.  ..||.|....|  .||. |. . |.... .   . |   .. .|.| ..   ..
QPWYHGNISREEAEQLLKNP------GMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFP--SL-ELVNHYQHNPLG
SH2 34112.AA SH2 1517-1589 25 7.3e-12 36.66 Pfam 1-72 (81) Show / Hide 
Range on Protein: 1517-1589
Range on HMM: 1-72/81
Sequence Identity: 25% (20 aa)

WLHRDLSREQADRILRSAAHDLSRSEGEGIYLVRTSEKAQNAYVVSLMSGG---APHHYLFREAEGG--FVLKGKFFR
| |...||..| |.|..      .   .| .||| ||  .. |..|.. .|     .||  .. ..|  ..  .. |.
WYHGKISRQEAERLLMN------PGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFC