Gene N13 (M.brevicollis)
N13
Species: M.brevicollis
Alias: N13
External Links:
Annotation:
Sequence
Protein domains of N13.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| VWD | N13.AA | VWD | 1-12 | 91 | 0.198933 | 6.58 | Pfam | 5-16 (163) | Show / Hide |
Range on Protein: 1-12 Range on HMM: 5-16/163 Sequence Identity: 91% (11 aa) GDPHYTTFDGKY ||||||||||.| GDPHYTTFDGRY |
|||||||||
| VWD | N13.AA | VWD | 129-147 | 57 | 0.002708 | 13.01 | Pfam | 138-156 (163) | Show / Hide |
Range on Protein: 129-147 Range on HMM: 138-156/163 Sequence Identity: 57% (11 aa) YQSNTVGICGNFNGNSGDD || | |.|||.||.. || YQNQTCGLCGNYNGEPRDD |
|||||||||
| EGF_2 | N13.AA | EGF_2 | 333-359 | 40 | 1e-07 | 27.63 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 333-359 Range on HMM: 1-29/29 Sequence Identity: 40% (13 aa) CPNSCSG-NGACN---NAKCVCDSG-FSGRDC | |.| .| || ||.||.| ..| .| C---CNGHHGTCNNQGCGKCQCDDGWWQGDHC |
|||||||||
| EGF | N13.AA | EGF | 333-358 | 22 | 0.002017 | 14.5 | Pfam | 1-36 (36) | Show / Hide |
Range on Protein: 333-358 Range on HMM: 1-36/36 Sequence Identity: 22% (8 aa) CPN---SCSGNGACNNA----KCVCDSG---FSGRD |. |...| |.. .| | | ..|.. CNPNNNPCHHHGTCVDTPGGYTCQCPPGYLGYTGKR |
|||||||||
| TIG | N13.AA | TIG | 367-480 | 16 | 0.003302 | 13.22 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 367-480 Range on HMM: 1-82/82 Sequence Identity: 16% (19 aa) PVITSLSATTCNI-KAAASC-ASDISVFGSNFWNAENLTCRYKVIASPAVASDSVLMVGESASRSAFFLGSSEVICQLPDRAVFVPAGLQGDLVTIEISV |.|||.| . . .. . |.. |.|| . |. ..| .. . |....|..| . .| ... . | PTITSIS-----PNTTGPPSGGTTITITGQNF---------------GNDS-DTKCYFGGTPCTVI-WWSSTQIVCTTPPHT-------PG-THNVSV-V STTDSIVSEASLPFTF . | ....||. NG---QWSSNPTTFTY |
|||||||||
| EGF | N13.AA | EGF | 494-508 | 46 | 0.169688 | 8.07 | Pfam | 1-15 (36) | Show / Hide |
Range on Protein: 494-508 Range on HMM: 1-15/36 Sequence Identity: 46% (7 aa) CAPNPDSCSIDGVCV |.||.. |. .| || CNPNNNPCHHHGTCV |
|||||||||
| EGF_2 | N13.AA | EGF_2 | 494-523 | 19 | 38.724466 | 0.79 | Pfam | 1-18 (29) | Show / Hide |
Range on Protein: 494-523 Range on HMM: 1-18/29 Sequence Identity: 19% (6 aa) CAPNPDSCSI-DGVCVLEGTHEASNVCRVCV | |. .|.|. .|..|. C------CNGHHGTCNNQ-------GCGKCQ |
|||||||||
| Cadherin | N13.AA | Cadherin | 654-737 | 36 | 2.7e-17 | 62.94 | Pfam | 1-94 (102) | Show / Hide |
Range on Protein: 654-737 Range on HMM: 1-94/102 Sequence Identity: 36% (34 aa) YTFNVTEDTPVGTVVGTIMAYDPD-EAGSLQYEWYSQVAGE---AGVLLIDESTGV---ITVGKALDYERV-SSYLLLVSVRDG--GLQHMASV |.| | |..|||| |.|. |.||| . | .. || . |. .. ||. ||. ||. | ||.| . | | |...|. | . . |. YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSST |
|||||||||
| CA | N13.AA | CA | 671-749 | 25 | 1.8e-13 | 52.01 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 671-749
Range on HMM: 1-121/121
Sequence Identity: 25% (32 aa)
IMAYDPDEA--GSLQY------EWYSQVAGEAGVLLIDESTG-----------VITVGKALDYERV---------SSYLLLVSVRDGG------------
. | |||| |. || | ||..|| .||. |.||.| ..| | | ..|||
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK
------LQHMASVHVFVGDVNEAPT
|. ..|...| |||. |
FQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| CA | N13.AA | CA | 771-850 | 22 | 1e-05 | 26.22 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 771-850
Range on HMM: 1-121/121
Sequence Identity: 22% (28 aa)
LTAQDQDAG----DSH-------TFSVGGTDAAYFQVVGAT-------------LQTAQELDYEALHAAGK----NPLAITITATDAGG-----------
.|| | |.| .. |.|. | .|.. | . |...||.|. . . .|..|||.||
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK
------LTLTKAFDITVQDVNEAPY
|. | . |.|.|||. |
FQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| Cadherin | N13.AA | Cadherin | 754-843 | 25 | 0.003004 | 14.01 | Pfam | 1-102 (102) | Show / Hide |
Range on Protein: 754-843 Range on HMM: 1-102/102 Sequence Identity: 25% (27 aa) SNNVVAENQPVGTVVANLTAQDQD----AGDSHTFSVGGTD---AAYFQVVG--AT---LQTAQELDYEALHAAGKNPLAITITATDA-G---GLTLTKA . | ||.|||| |...||.| | . . ..| |.. . | . . . |...||.|. . .|. |||. . ... | YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQ----NGQYHLTVMATDHDDGGPPRSSTTT FDITVQ |||. VTITVC |
|||||||||
| CA | N13.AA | CA | 871-949 | 22 | 3.2e-08 | 34.55 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 871-949
Range on HMM: 1-121/121
Sequence Identity: 22% (28 aa)
VTVQDQDAG-----QT------VTCTIVQESTPTFELLDMK-------------LYALPGQQLDHETN---------PSIELTIGCADDGTPM-------
||. | |.| ||..||. |.. . .... ..||.|. |. .||. | |.|
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTT--KPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPT
--------KYATATFTITVLDAFDMPG
. .|.|.||.||| | |
RKFQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| Cadherin | N13.AA | Cadherin | 907-942 | 35 | 9.2e-05 | 19.28 | Pfam | 64-102 (102) | Show / Hide |
Range on Protein: 907-942 Range on HMM: 64-102/102 Sequence Identity: 35% (14 aa) QQLDHETN-PSIELTIGCADD--GTPMKYATATFTITVL ..|| |. . .||. . | |.| ...|.| ||||. KPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTITVC |
|||||||||
| Cadherin | N13.AA | Cadherin | 955-978 | 45 | 0.010976 | 12.05 | Pfam | 1-24 (102) | Show / Hide |
Range on Protein: 955-978 Range on HMM: 1-24/102 Sequence Identity: 45% (11 aa) QPETIYENATIGTVVGTVVAVDQD .. .. ||| .|| |.|| |.| | YHFSVCENAPVGTFVMTVTATDPD |
|||||||||
| Cadherin | N13.AA | Cadherin | 1072-1167 | 25 | 2.5e-09 | 35.17 | Pfam | 1-102 (102) | Show / Hide |
Range on Protein: 1072-1167 Range on HMM: 1-102/102 Sequence Identity: 25% (27 aa) TGGTVEENLALGGVIGTISAQDPD-----QGQTHTFSLASH---QDRFTLSNDASGMYATIRLSQTAASPLNYDSE-PSIELSIVVLDS--GNPPRSITT ..|.|| . | ..|. |.||| .. . . | . . |.. | . .... |. |.. . . .|.... |. | |||| || YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDN---GIITTTKP--LDREQQNGQYHLTVMATDHDDGGPPRSSTT SITITVE ..||||. TVTITVC |
|||||||||
| CA | N13.AA | CA | 1089-1170 | 19 | 2.9e-05 | 23.27 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 1089-1170
Range on HMM: 1-121/121
Sequence Identity: 19% (25 aa)
ISAQDPDQG-----QT------HTFSLASHQDRFTLSNDASGMYA-----TIRLSQTAASPLNYDSE---------PSIELSIVVLDSGNPP--------
..| |||.| |.|. . |.. . |. | .. | ||.... |. .| ... |.|.||
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTT--KPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR
-------RSITTSITITVEN----QP
.| |...||.|. |
KFQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| CA | N13.AA | CA | 1309-1393 | 17 | 0.001613 | 5.39 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 1309-1393
Range on HMM: 1-121/121
Sequence Identity: 17% (22 aa)
LVASDPEG------GD------VTFSMASSSSQVMQTYFQVSTTIRG--------TFELSVIQNLAMANIAS-------GDYNLDVQAEDATG-------
..|.|| |. ||.|. . .|.. .. .... . | .. |.| ||| |. |
VTATDPDEGHNGPNGQPNDPEMVTYSIVG--------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSH
----------HSSTQRVVVTLTDGTTDPS
.||| |.....| |
PTRKFQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| CA | N13.AA | CA | 1197-1282 | 15 | 0.004293 | 1.04 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 1197-1282
Range on HMM: 1-121/121
Sequence Identity: 15% (20 aa)
VGKFVLQGN---DNQA------ATYSV-RFADNRRRAADAFSIQGLN-------------LVLSSPLDAEEV---------QTQSLNVVAVETIGSEVN-
| . .| |||. . ||| . .... ||| || .. .|.|.|. | .
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPD
------------YYAAQQLTINIQNEDEAPV
. ..||... ... |
SHPTRKFQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| Cadherin | N13.AA | Cadherin | 1360-1386 | 35 | 0.459721 | 6.4 | Pfam | 72-102 (102) | Show / Hide |
Range on Protein: 1360-1386 Range on HMM: 72-102/102 Sequence Identity: 35% (11 aa) SGDYNLDVQAEDA----TGHSSTQRVVVTLT .| |.| | | |. .. ||| .|..|.. NGQYHLTVMATDHDDGGPPRSSTTTVTITVC |
|||||||||
| TIG | N13.AA | TIG | 1283-1337 | 18 | 2.740044 | 3.34 | Pfam | 37-82 (82) | Show / Hide |
Range on Protein: 1283-1337 Range on HMM: 37-82/82 Sequence Identity: 18% (10 aa) FGSSSYTATVDTTTVSAGDLVVLSPALVASDPEGGDVTFSMASSSSQVMQTYFQV ||.. | . ..|. .|. .|... |. ..|.. . . .. .. | |.. FGGTPCTVI----WWSSTQIVCTTPPHT---PGTHNVSV-VNG-QWSSNPTTFTY |
|||||||||
| Cadherin | N13.AA | Cadherin | 1183-1275 | 20 | 10.616814 | 1.65 | Pfam | 1-102 (102) | Show / Hide |
Range on Protein: 1183-1275 Range on HMM: 1-102/102 Sequence Identity: 20% (21 aa) NSLTVSESTSVGTVVGKFVLQGND-----NQAATYSVRFADNRRRAADAFSIQGLNLV-----LSSPLDAEEV-QTQSLNVVAVETIGSEVNYYAAQQLT . .|.| ..||| |. . . | |. ..|| . . .. |.|. . . . ||| |. .. .|.|.|. . . . .. ..| YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPD--PGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVT INIQ |... ITVC |
|||||||||
| SH2 | N13.AA | SH2 | 1479-1569 | 32 | 4.9e-14 | 53.86 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 1479-1569 Range on HMM: 1-87/87 Sequence Identity: 32% (30 aa) YEWYQPEMTRQDCSSELAT--AAPGTFLVRDSKATPGWHILGVKTENDVLHEKIRATDDGMYQLLPSSGPAHEQPRFGDLPSLINHYGSRQSG ..|| ..|... . | . .|.|||||| .|| .| |.... | | .|| .|||.| . . ..| .| |.||| | QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDET-----WRRKFPSL-ELVNHYQHNPLG |
|||||||||
| SH2 | N13.AA | SH2 | 1481-1563 | 32 | 7.2e-11 | 33.73 | Pfam | 1-81 (81) | Show / Hide |
Range on Protein: 1481-1563 Range on HMM: 1-81/81 Sequence Identity: 32% (29 aa) WYQPEMTRQDCSSELAT--AAPGTFLVRDSKATPGWHILGVKTEN---DVLHEKIRATDDGMYQLLPSSGPAHEQPRFGDLPSLINHY || . ..||. | .||||||.| ||| | |.... | | .|. ||.| | . . ..|..|. |..|| WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYIT-------GRHKFCSLQELVEHY |
|||||||||