Gene N1 (M.brevicollis)

N1

Species: M.brevicollis
Alias: N1
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
N1.AA Protein None 1131 None Fasta, JSON

Protein domain

Protein domains of N1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RhoGAP N1.AA RhoGAP 428-600 24 4.3e-41 143.75 SMART 1-193 (193) Show / Hide 
Range on Protein: 428-600
Range on HMM: 1-193/193
Sequence Identity: 24% (49 aa)

DHIPRLVHSIMQLVERRGLMYEGIYRVSGSLPRVDKLKAAALMQGPHV--------------LEDAEIPELTSLLKLVLKSMNPPLLTFAAHAAFCRAIR
.|||..| .... .|..|.  |||||..|.  |...|..|    .. .              .|....  ....||. . ..  ||.||...  | .|..
SHIPIIVRKCIEYIEKHGMDTEGIYRKCGNQSRIQELRNAFDRGPD-DLCSTDNYITHEFNDWEEWDVHDVAGVLKQYFRELPEPLITFELYEEFIEAMK

L--------------PEGETRNEALSAALRVLPTKNYRLLDSLMRHLRRVVAECSSNRMNQENIALVFGPTIARSPRGLQGDLQDNGAHILIAKALVQLP
.              .. |.| .||  ... ||. ....|. || ||.|| .  ..|.|| .| |..||||. ..|      ..|.  .. . . |.. .
CYQIEQTSRKQWNHSEDEEERIHALHQLISQLPPCHRNTLRYLM-HLNRVAEHSDVNKMNAHNLAICFGPTLFWPP------MMDMRHQNKCVEFLIEHY

A
 
D
RhoGAP N1.AA RhoGAP 431-581 33 7.3e-41 140.41 Pfam 1-156 (156) Show / Hide 
Range on Protein: 431-581
Range on HMM: 1-156/156
Sequence Identity: 33% (53 aa)

PRLVHSIMQLVERRGLMYEGIYRVSGSLPRVDKLKAAALMQGPH---VLEDAEIPELTSLLKLVLKSMNPPLLTFAAHAAFCR--AIRLPEGETRNEALS
|. | .  . .|..||  ||||||||.  |...|..|           .|.  .  ..|.||. . ..  ||.||... .| .  | .... |.| ||..
PMIVRKCIEYIEQHGLDTEGIYRVSGNKSRIKELREAFDRGPDVDLNDWEWHDVHDVASVLKQYFRELPEPLFTFELYEEFIEAMAAKIEDEEERIEAMR

AALRVLPTKNYRLLDSLMRHLRRVVAECSSNRMNQENIALVFGPTIARSPRGLQGD
...| ||  ||..|  |||||.|| . .. |.|| .|.|..|||.. ..| . ..|
ELIRKLPPPNYDTLRYLMRHLHRVAQHSDVNKMNAHNLAICFGPNLFWPPDDDSMD
SH2 N1.AA SH2 819-902 28 6.5e-09 36.86 SMART 1-87 (87) Show / Hide 
Range on Protein: 819-902
Range on HMM: 1-87/87
Sequence Identity: 28% (25 aa)

QPWYRPAVTRDDMVG-LKT--LTPGSFIVYPSKTDPGNFCLSAWTGEQVWTGLIVVGEDGECSLEN-TDDAFDDVVDLVEHYSEDPTP
||||   ..|.. .  ||.    .|.|.| .| ..|| ..|| .....|   .|   .||  ...  ..  |... .||.||.  | .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 N1.AA SH2 882-896 40 0.057422 7.6 Pfam 67-81 (81) Show / Hide 
Range on Protein: 882-896
Range on HMM: 67-81/81
Sequence Identity: 40% (6 aa)

TDDAFDDVVDLVEHY
... |... .|||||
GRHKFCSLQELVEHY
SH2 N1.AA SH2 821-864 24 0.077359 7.22 Pfam 1-50 (81) Show / Hide 
Range on Protein: 821-864
Range on HMM: 1-50/81
Sequence Identity: 24% (12 aa)

WYRPAVTR---DDMVGLKTLTPGSFIVYPSKTDPGNFCLSAWTGE---QV
|| . ..|    ..    . ..|.|.| .| . || . || ...    .|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRV