Gene 10594 (M.brevicollis)

10594

Species: M.brevicollis
Alias: 10594
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
10594.AA Protein None 1319 None Fasta, JSON

Protein domain

Protein domains of 10594.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Sam7 10594.AA sam7 32-93 30 3.6e-17 58.87 In-house 1-70 (70) Show / Hide 
Range on Protein: 32-93
Range on HMM: 1-70/70
Sequence Identity: 30% (21 aa)

WSTRDVGRWLESVHM---SELKRSFKAHRI-----DGNRLLALHADDLTRLGLESPSQQRLLLHNIQQLR
|...||. |||...|   .. . .|..|.|     ||  |. .  .|| ..|  .|  .. ... |||.|
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM_1 10594.AA SAM_1 30-93 31 3.6e-14 53.18 Pfam 1-66 (66) Show / Hide 
Range on Protein: 30-93
Range on HMM: 1-66/66
Sequence Identity: 31% (21 aa)

AKWSTRDVGRWLESVHMSELKRSF-KAHRIDGNRLLALHADDLTR-LGLESPSQQRLLLHNIQQLR
  |. .||. |||| .|.. . .| .|..||.  || . ..|| . .|  .|  .  ... ||.|.
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGVTLPGHRKKIMYSIQMLK
SAM 10594.AA SAM 29-95 33 6.2e-14 53.53 SMART 1-67 (67) Show / Hide 
Range on Protein: 29-95
Range on HMM: 1-67/67
Sequence Identity: 33% (23 aa)

AAKWSTRDVGRWLESVHMSELKRSFKAHRIDGNRLLALH-ADDLTRLGLESPSQQRLLLHNIQQLRIV
.  |. .||..||||  |.. |  |....|||  ||.|   .||...| ..|  .. .|. ||...  
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_2 10594.AA SAM_2 29-93 28 6.6e-14 50.56 Pfam 1-71 (71) Show / Hide 
Range on Protein: 29-93
Range on HMM: 1-71/71
Sequence Identity: 28% (20 aa)

AAKWSTRDVGRWLESVHM-SELKRSFKAHRIDG-NRL-LALHADDL--T-RLGLESPSQQRLLLHNIQQLR
   |.. ||. ||.|..|  . | .|..| |.|   | . . .|||  . |.| ... ... ... ||...
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SH2 10594.AA SH2 402-418 35 1.7 3.28 Pfam 65-81 (81) Show / Hide 
Range on Protein: 402-418
Range on HMM: 65-81/81
Sequence Identity: 35% (6 aa)

YADGPAFSRLAVLVEYY
..... |. |. |||.|
ITGRHKFCSLQELVEHY
SH2 10594.AA SH2 959-1050 29 5.4e-12 47.09 SMART 1-87 (87) Show / Hide 
Range on Protein: 959-1050
Range on HMM: 1-87/87
Sequence Identity: 29% (28 aa)

SDWYWYQAGKPRSAAIQELDH--CPDGAFIIRRSESNPACFALTYKALGRFWDELVVVPS-GSLYGPGIHFDSDPRLRFRSLEELVQYYAQPSSP
  ||.     .|. | | | .  .|||.|..| ||||| ...|...  |..   ..     |. |  .      .| .| || |||..| ... .
QPWYHGNI--SREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDET-----WRRKFPSL-ELVNHYQHNPLG
SH2 10594.AA SH2 1031-1044 57 0.002435 11.63 Pfam 68-81 (81) Show / Hide 
Range on Protein: 1031-1044
Range on HMM: 68-81/81
Sequence Identity: 57% (8 aa)

RLRFRSLEELVQYY
| .|.|| |||..|
RHKFCSLQELVEHY
SH2 10594.AA SH2 981-1000 50 0.002454 11.62 Pfam 21-40 (81) Show / Hide 
Range on Protein: 981-1000
Range on HMM: 21-40/81
Sequence Identity: 50% (10 aa)

PDGAFIIRRSESNPACFALT
|||.|..| |||.| ...|.
PDGTFLVRESESTPGDYTLS
SH2 10594.AA SH2 1291-1305 26 0.473468 4.91 Pfam 67-81 (81) Show / Hide 
Range on Protein: 1291-1305
Range on HMM: 67-81/81
Sequence Identity: 26% (4 aa)

GSPVCQTLSELINYH
| . ...|.||....
GRHKFCSLQELVEHY