Gene 25221 (M.brevicollis)

25221

Species: M.brevicollis
Alias: 25221
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
25221.AA Protein None 839 None Fasta, JSON

Protein domain

Protein domains of 25221.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 25221.AA SH2 20-132 26 2.9e-14 54.64 SMART 1-87 (87) Show / Hide 
Range on Protein: 20-132
Range on HMM: 1-87/87
Sequence Identity: 26% (30 aa)

PRWYHGVMSRRDAEMILAKDGIVAGMFPAPCRRASASRPCVGHNGTFLVRASTK-GDSFVLSACSEGRIDHYQIEENTDSAKAPFLQFRLDTGMSPKFRS
  |||| .|| .|| .| .                      ...|.|||| | .   ..||| ...|.. ||.|..| |       ....|.  ..|| |
QPWYHGNISREEAEQLLKNP--------------------GMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD------GKYYIDETWRRKFPS

LSSVLHYLLEHPHH
|   ...   .|  
L-ELVNHYQHNPLG
SH2 25221.AA SH2 22-126 23 6e-13 39.85 Pfam 1-81 (81) Show / Hide 
Range on Protein: 22-126
Range on HMM: 1-81/81
Sequence Identity: 23% (26 aa)

WYHGVMSRRDAEMILAKDGIVAGMFPAPCRRASASRPCVGHNGTFLVRAST-KGDSFVLSACSEG---RIDHYQIEENTDSAKAPFLQFRLDTGMSPKFR
|||| .|| .|| .| .                      ...|||||| |  .  ...|| . .|   |. ||.| .. .       .. . ..    |.
WYHGKISRQEAERLLMN--------------------PGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNG------GYYITGRHK--FC

SLSSVLHYL
||.   .. 
SLQELVEHY
PH 25221.AA PH 453-579 23 9.6e-17 63.02 Pfam 1-92 (92) Show / Hide 
Range on Protein: 453-579
Range on HMM: 1-92/92
Sequence Identity: 23% (30 aa)

VLREGYLSKLPPRNNRVQGWKRRWFKLVVSLDRSLSGGPVYLEYYTSHLRSKPKGVIDLDKIRSVGPPSADILATDRQYRNVPKLTMNFARQDSLFEVHL
| .||.|.|.     .  .||.||| |             .| || ..  ..|||.|.|... .| ...                      ..  |... 
VIKEGWLHKKG----KRKSWKKRWFVLFN----------NCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDN-------------------KRPHCFQIRT

PRR-TYRLMASSRAEARDWMSMLEEVIG
  | || . |.|  |..|||. ..... 
-DRRTYYFQAESEEEMNDWMQAIQSACR
PH 25221.AA PH 453-581 24 2.1e-16 61.77 SMART 1-82 (82) Show / Hide 
Range on Protein: 453-581
Range on HMM: 1-82/82
Sequence Identity: 24% (32 aa)

VLREGYLSKLPPRNNRVQGWKRRWFKLVVSLDRSLSGGPVYLEYYTSHLRSKPKGVIDLDKIRSVGPPSADILATDRQYRNVPKLTMNFARQDSLFEVHL
|..||.|.|.        .||.||| |             .| || ..   ||||.|.|... .| .                            ||.| 
VIKEGWLYKKS-----K-RWKKRWFVLFN----------DCLYYYKDK---KPKGSIPLSDC-TVRE-P-------------------------CFEIHH

PRRTYRLMASSRAEARDWMSMLEEVIGLE
  ||| . ..|  |...||. ....|   
-DRTYYFQCESEEEMQEWMQAIQKAIHNN
IRS 25221.AA IRS 624-690 31 3.2e-08 32.2 Pfam 34-106 (106) Show / Hide 
Range on Protein: 624-690
Range on HMM: 34-106/106
Sequence Identity: 31% (23 aa)

QL--IDPTNSEVLIEWKYSVLRSYGY-IGHVCWFEAGRRAPTGPGIMCFSVSQ---SKQMFDILHALVTPLVR
.|   |.   ..|..| |  || ||.    .  ||||||.|||.|.  |....     ..|...|| .  . .
TLVWDDHNPRCPLVSWPYMCLRRYGHMDKNMFSFEAGRRCPTGEGEFWFQTQDSVVAEEIFETVHAAMKAQKE