Gene 25780 (M.brevicollis)

25780

Species: M.brevicollis
Alias: 25780
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
25780.AA Protein None 1028 None Fasta, JSON

Protein domain

Protein domains of 25780.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 25780.AA SH2 295-385 26 2.8e-11 44.73 SMART 1-87 (87) Show / Hide 
Range on Protein: 295-385
Range on HMM: 1-87/87
Sequence Identity: 26% (24 aa)

RHFYHGNLDKATAEARLQACGNEDGTFLIRARANTANADLNESVISVVYKGKPTHHLLIKTGSHAYALNK-GTVEASNLSEVVESLRNAKPF
 ..||||.... ||. |.. |..||.||.| . .    . .. |.|| .|||  | .. ....  | .   . .  ..| | |.  .  .  
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES----NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 25780.AA SH2 297-349 33 2.1e-10 32.39 Pfam 1-52 (81) Show / Hide 
Range on Protein: 297-349
Range on HMM: 1-52/81
Sequence Identity: 33% (19 aa)

FYHGNLDKATAEARLQACGNEDGTFLIRARANTANADLNESVISVVYKG---KPTH
.|||.. .. || .|.. ||.|||||.| . .| .      ..||...|   . .|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD----YTLSVRDDGPGDRVKH
SH2 25780.AA SH2 446-528 26 0.000193 13.02 SMART 5-87 (87) Show / Hide 
Range on Protein: 446-528
Range on HMM: 5-87/87
Sequence Identity: 26% (23 aa)

HGVLSKDQAAALVEHEAAGMDGVYLLRHSKG--GGYIISVLYHGKCTHHLVQKSEPGGTFVVNK-KVTKAVTLDEVVVLLQSKHPW
|| .|...| .|  ..  . || .|.| |    |.|..|| ..||. | ....... | ...     .|  .| | |   |     
HGNISREEAEQLLKNP-GMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 25780.AA SH2 446-504 29 0.000273 14.42 Pfam 3-65 (81) Show / Hide 
Range on Protein: 446-504
Range on HMM: 3-65/81
Sequence Identity: 29% (19 aa)

HGVLSKDQAAALVEHEAAGMDGVYLLRHSKG--GGYIISVLYHG---KCTHHLVQKSEPGGTFV
|| .|. .|  |      ..|| .|.| |    |.| .||.. |   . .|  .|. . || ..
HGKISRQEAERLLMN-PGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYI
SH2 25780.AA SH2 772-824 32 2e-06 20.47 Pfam 1-54 (81) Show / Hide 
Range on Protein: 772-824
Range on HMM: 1-54/81
Sequence Identity: 32% (18 aa)

FFFASLNQERAEELLATPPIIEGKFLVRSVPRRRTNDHFILSVVHEG---QQRHYR
... ... . ||.||  |   .| ||||  ....|  .. |||...|   . .|||
WYHGKISRQEAERLLMNPGNPDGTFLVR--ESESTPGDYTLSVRDDGPGDRVKHYR
SH2 25780.AA SH2 770-854 22 0.000634 7.49 SMART 1-87 (87) Show / Hide 
Range on Protein: 770-854
Range on HMM: 1-87/87
Sequence Identity: 22% (21 aa)

PAFFFASLNQERAEELLATPPIIEGKFLVRSVPRRRTNDHFILSVVHEGQQRHYRLVRRAPTEALSEVASLSG---------SAITTSQWEAEG
  ...  .. | ||.|| .|   .| ||||   .  .. ...||| ..|. .|||. | ..        .. .           .   |  . |
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES--NPGDYVLSVRWKGKVKHYRIRRNDD-----GKYYIDETWRRKFPSLELVNHYQHNPLG