33367

Species: M.brevicollis
Alias: 33367
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
33367.AA Protein None 558 None Fasta, JSON

Protein domain

Protein domains of 33367.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PID 33367.AA PID 71-140 24 6.7e-09 33.03 Pfam 80-153 (153) Show / Hide
Range on Protein: 71-140
Range on HMM: 80-153/153
Sequence Identity: 24% (18 aa)

EVILNNSVYEIAHCGV--DVS-KPRLFTV-IVGKKESSDFFCHVFKCASKDSAARFVKAVASACTLAYQNYQKK
|.. .  .. |  |..  |.    | |   |....... | ||||.|  ...| . . .|  |. ..|| ....
ECMHDHPMRNISFCADGGDPHVDMRYFAYDICRDGPCQRFACHVFWCCKTQQAQDIAQTVGQAFQVCYQQCLRA

PTB 33367.AA PTB 1-143 19 6.5e-07 30.22 SMART 1-156 (156) Show / Hide
Range on Protein: 1-143
Range on HMM: 1-156/156
Sequence Identity: 19% (32 aa)

MSFMHQEVKYRGMEPVLGWQPTQAQPR------PGLIEANACVKRLFVRPKQSRLSVISCSPDGGLQCVDTSYNPPEVILNNSVYEIAHCGVDV------
 . .. .|.|      ||. .. ...|       |.  ...| ...    |. .  ... |.| |. ..|   .  .||.. ... |..|..|       
PWGCCFNVWY------LGCVEV-PHHRNSMAPGKGMQVCQECMRKIRQHWKHWQKMHLHISVD-GVKLIDPQTK--QVIHHHPIHRISFCAHDPYRWNTG

-----SKPRLFTVIVGKKESS-------DFFCHVFKCASKDSAARFVKAVASACTLAYQNYQKKKSA
     . .|.| .|.... ..        | ||||.|...  | . . ..  |. ..||  ||....
GHHCCDDDRCFGYICRHPNDRGSHRMTYWFRCHVFWCEDPH-AEDIAQTIGQAFQVCYQQCQKQRCQ

SH2 33367.AA SH2 224-308 28 4.4e-15 57.36 SMART 1-87 (87) Show / Hide
Range on Protein: 224-308
Range on HMM: 1-87/87
Sequence Identity: 28% (25 aa)

DSWFRPSMSRAEVASILRG--GRIGDFIVRESQTRPGDYAISVQTGAQIWTGLIPHAP-RGFQLGERGGVSFAELTDLIAHYAQNTFM
  |.   .||.|. ..|..  .. |||.||.|.. ||||..|| .. ..   .| . . ... ..| ....|  | .|..|| .|   
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 33367.AA SH2 226-264 41 5.5e-14 42.89 Pfam 1-41 (81) Show / Hide
Range on Protein: 226-264
Range on HMM: 1-41/81
Sequence Identity: 41% (17 aa)

WFRPSMSRAEVASILRG--GRIGDFIVRESQTRPGDYAISV
|. ...||.|.  .|.   .. |.|.||||.. ||||..||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSV

SH2 33367.AA SH2 288-302 40 0.154254 6.34 Pfam 67-81 (81) Show / Hide
Range on Protein: 288-302
Range on HMM: 67-81/81
Sequence Identity: 40% (6 aa)

GGVSFAELTDLIAHY
|.. |. | .|. ||
GRHKFCSLQELVEHY

EH 33367.AA EH 462-551 24 1e-06 24.28 SMART 1-98 (98) Show / Hide
Range on Protein: 462-551
Range on HMM: 1-98/98
Sequence Identity: 24% (24 aa)

HATLSEVAEAIFSELADAVDE--EDCVGGNDVRPILLRSGLEISMLGSIWMMVDEERRGKLDRQ-QLIHVLGLISQAQEG-----AELDVGTVKATDR
   .|   .| .... .. |   .  | |...|||...|||  . |. || ..|    |.|||. . .  . || ....|     ..|.   .   .|
PWWISPEDKAKYWQIFHSLDPQQDGFVTGDQARPIFMQSGLPQQQLAHIWNLCDIDNDGELDREPEFCVAMHLIYCCMNGNYPIPMVLPPWLIPPSKR