Gene 33775 (M.brevicollis)
33775
Species: M.brevicollis
Alias: 33775
External Links:
Annotation:
Sequence
Protein domains of 33775.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| B41 | 33775.AA | B41 | 24-202 | 23 | 7.6e-30 | 106.39 | SMART | 1-232 (232) | Show / Hide |
Range on Protein: 24-202 Range on HMM: 1-232/232 Sequence Identity: 23% (54 aa) KRGDYVCVIRHLDNTEHSIYISGKATGDEVFRAFLREIEPL--PETDYFALYFPSK------------------S----RTVTLEFGVKFFVAD----PR .. . .| .. .|.| .. . ..|| ..... |... . |..||.|.. .. . . || | |||.. | | SPKPRFCRVYFMDGTTLEFEVDSSTTGQDLCDHVCRHCG-ISPREHWYFGLWYEDPHEDRHWLDHWKTIMKQDVKWHKSEPWTLHFRVKFYPPDWHGFPN QLQHDHTRF-LYYCQLKEDLASGRFVAP-HDVCWQLCAYIVQADIGDFNIS--------RCPEGYLSDMLLLPDQ---------------KPEDEDEIRN |||.| ||. ..|.|...|. .||. | . |.||.|..||.. ||.. . .. ..|.|. .||.| ..| .. |.. QLQEDPTRYNYFYLQCRHDILQGRHPCPHEEECLQLAALQVQIEYGDYDPEETNNKKMTKHVQKYKSYKRFLPKQWIDSIKQSFMHYQMHHKEWRKRIME LHVQLEDMTADEAMLAFLELASQQL-LYGLDIH .| .. || .||.| .|.... .|| . . WHKNHCGMTPEEAKLKYLQICQRWPPMYGVEHF |
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| FERM_M | 33775.AA | FERM_M | 93-202 | 18 | 5e-23 | 80.32 | Pfam | 1-171 (171) | Show / Hide |
Range on Protein: 93-202
Range on HMM: 1-171/171
Sequence Identity: 18% (31 aa)
DPRQ-LQHDHTRFLYYCQLKEDLASGRFVAPHDVCWQLCAYIVQADIG-DFN-ISRCPEGYLSDML--------------------LLP-----------
|| .|.. || ..|.|.|.|. ||. .. . ...| ||..|...| |.| . ...|. . . ..|
DPNRDIQDEVTRHQFYLQAKWDILEGRYPCSEEEALMLAAYQCQIEFGSDYNPPQKHKSDYMEKEWWEQQEGMEVWLRCDNEQQERYWPAHCRLASKGRT
-------------------------DQKPED-EDEIRNLHVQLEDM-TADEAMLAFLELASQQLLYGLDIH
..| .. |..| .| ... | ...|||| ....... || . .
MADSSYSEVSIRINPHCYVSPWYCKKMKQKQWEQRILEQHKNHRGMCSPEEAMLQYIQICQRWPMYGVHFF
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| GuKc | 33775.AA | GuKc | 697-872 | 21 | 2.8e-05 | -16.26 | SMART | 1-203 (203) | Show / Hide |
Range on Protein: 697-872 Range on HMM: 1-203/203 Sequence Identity: 21% (44 aa) APRPVVLLGA---GKANVEAALLERFPD--AYRLVRHDATDSH--GEAE----SYRFVD-LDTFIHQAMRDEYAEVVRYGSD-LYGLPYA-SLRTDEDGR .||.||.|. || . ..|....|| .. . | .. || . | ||. . . . .... | | . .|| . . | |. HRRPIVLSGPSGVGKSTLKHMLMQEYPDYPKFEFSVPHTTRPPRPGEVNGCVVDYHFVSLKEEMEQMIKHNKFLEWGEYHGNLYYGTSKETVRQVHEQGK HPVIPICDPLVITTLQKH----GVFPIVIFLD--CDTSRRARLV----MPHDSASRVHAEVQL-AAKVKSHF---HAYFSGQVFPANSLEDVA-EVVHEV | .. | | . |... |||||. . . ||. . ... | ... . | | | |..| ... ..||| . |. HCILDID-PQGVRQLRYARRYSYFYPIVIFIKPPSMEELEERLRQPCQRGTETEERIQKRLAHQAQKEMQHYPKCHHEFDYVI-VNDDLEDACYKELKEI VSTVQ . . | MEQEQ |
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| PDZ | 33775.AA | PDZ | 1002-1078 | 22 | 2.5e-15 | 58.16 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1002-1078 Range on HMM: 1-80/80 Sequence Identity: 22% (20 aa) AGYGFGFREGSESWCQNLPVVTSITAGGAAHLDGR-----LQSEDVLVEVNG-KGLASKSYVEVLTMIRGHSG-----ALRMTVKRRC .|.|| .. ...|. .||.|. .|| |. |...|||| . . .... ... |... .| ...||.|. GGLGFSIVG--------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | 33775.AA | PDZ | 994-1075 | 18 | 5.8e-14 | 50.39 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 994-1075 Range on HMM: 1-86/86 Sequence Identity: 18% (16 aa) SIRIPRTIAGYGFGFREGSESWCQ--NLPVVTSITAG-GAAHLDGRLQSEDVLVEVNGKGLASKSYVEVLTMIRGHSG-ALRMTVK ...... . |.||. ...... . ..... .| |||. .||.. |.....||. ... . .. .|.| .| ...|.. QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | 33775.AA | PDZ | 1088-1162 | 19 | 4.3e-16 | 60.72 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1088-1162 Range on HMM: 1-80/80 Sequence Identity: 19% (17 aa) GKYGMGIRGGADSKTPVLISRIAEGSAAADEPQ-----IQIGEEITHING-TDVTQLTHAEVLALIKSSPS-----SLNLVIHPRR | .| |.| ...||.. .|..|. ...| .|. .|| ..|. .||.......|... .. |.. .. GGLGFSIVG------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | 33775.AA | PDZ | 1080-1159 | 29 | 6.3e-16 | 57.14 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 1080-1159 Range on HMM: 1-86/86 Sequence Identity: 29% (25 aa) EVTLLARDGKYGMGIRGGADSK----TPVLISRIAEG-SAAADEPQIQIGEEITHINGTDVTQLTHAEVLALIKSSPS-SLNLVIH .||| .|. |.|... .. ... ||.. .| .||. . |..| |. |||.|.. .||... ..||.|.. .. |.| QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PTPc | 33775.AA | PTPc | 1746-1988 | 25 | 5.7e-71 | 243.0 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 1746-1988 Range on HMM: 1-308/308 Sequence Identity: 25% (81 aa) AISAMRRGLVKSR------------DCSLALKPENA--VRNRYR-DILPYDDTRVKLDS--------SNNDYINANHLSFESNGTTFSYIASQASLGPFL .... | . . .|. | .|||. .|||. ||..||.||||| . ...||||||. ... . ...||. |. | GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPL---- GPKPETSEHFWQMVWEQQVRLICMLTTLVEG--------GRTKCHQYWPSAPGDTCQFGDFSIVLNKEAARK-GYILRDITVQRANA--------KGKRR |.| |.||.|||.|... | ||....|. || |||||||. ....|.... . .| . .|..|...|. . . .| ---PHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRT LFQLQFTAWPDHGLPTSSAEMLTLVKEINNLKSRL-------------------VKP---------------------MPLLEKAKEVNIPAILSQLREQ . ....|.||||| | |. .| ....... .|.. | . ..|. |.|. |....|.| VTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQ RMNLVQTQDQYKFVCGTVMALSK |...||| .||.|.. .. . | RPGMVQTEEQYIFCYRCILEYIK |
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| Y_phosphatase | 33775.AA | Y_phosphatase | 1768-1938 | 35 | 2.5e-61 | 214.86 | Pfam | 1-172 (243) | Show / Hide |
Range on Protein: 1768-1938 Range on HMM: 1-172/243 Sequence Identity: 35% (65 aa) NAVRNRYRDILPYDDTRVKLD----SSNNDYINANHLSFESN-GTTFSYIASQASLGPFLGPKPETSEHFWQMVWEQQVRLICMLTTLVEGGR-TK-CHQ | .|||.||..||.||||| . ||||||. . . . . ||. | ||.|.| |.||.|||.|... | ||....|.|| | ||| NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG--PYWNPKAYICTQ-------GPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQ YWPS-APGDTCQFGDFSIVLNKEAARKGYILRDITVQRANA--KGKRRLFQLQFTAWPDHGLPTS-SAEMLTLVKEINNLKS |||. . |.....|||.. . .| ..|..|. .|. .. . .|.. ....|.||||| | | . || ....... .. YWPDNKEGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP |
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| Y_phosphatase | 33775.AA | Y_phosphatase | 1944-1985 | 30 | 2.1e-10 | 37.68 | Pfam | 202-243 (243) | Show / Hide |
Range on Protein: 1944-1985 Range on HMM: 202-243/243 Sequence Identity: 30% (13 aa) MPLLEKAKEVNIPAILSQLREQRMNLVQTQDQYKFVCGTVMA . ..|. ..|.|. |....|.||...||| .||.|.. ... CQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| PTPc_motif | 33775.AA | PTPc_motif | 1905-1985 | 19 | 2.8e-08 | 34.76 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 1905-1985 Range on HMM: 1-92/92 Sequence Identity: 19% (20 aa) RLFQLQFTAWPDH-----GLPTSSAEMLTLVKEINNLKSRLVKPM------------------PLLEKAKEVNIPAILSQLREQRMNLVQTQDQYKFVCG . ....|.|||| |.|. .|........ |. .... |.| .. ..|.||...||| .||.|.. TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ---VDIFQTVKEMRKQRPGMVQTEEQYIFCYR TVMA .. CILE |
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