Gene n922 (Tetrahymena)

n922

Species: Tetrahymena
Alias: 922, 110.m00130, n922
External Links:
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
n922.AA Protein None 551 None Fasta, JSON
n922.NA RNA None 1656 None Fasta, JSON
n922.kin_dom Protein Kinase Domain None 54 None Fasta, JSON

Protein domain

Protein domains of n922.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n922.AA CK1 128-317 25 7.1e-32 108.49 In-house 107-339 (339) Show / Hide 
Range on Protein: 128-317
Range on HMM: 107-339/339
Sequence Identity: 25% (61 aa)

ITESYGPSLKILFS--LMKNN-LSISTICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVIHN-------------DLKSTQLYLIDFKYAR-KYKHKNG--
. . .||.|  |.    | |. .| .|. | .| ||..||..|. ...||..||  ...               . .. |.|.|||  || ||. |.|  
VMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHN

----------QLVRYNE--NNRIMNKIFCNKFSSIGTHLGITPSRKDDLESLGYILIYLTRKGN---LFGSK-HFK-----TREEKLKYYEEQKLSLIPE
          |. .. |   .. .    . .. || .|||. ..|.|||.|..| ||.... ..     . | . |      ...| ..  |.|.|. ..
RWNGPRDKTWQHRPPREHKKKKGFRGC-TARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFF

TLGD------LPAEFVNYLNYIKSMNIMDHPEYDVW
 |.       .| ||  ...||.|..  | |.|.  
-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase n922.AA CK1-D 133-317 33 1.3e-31 108.68 In-house 78-261 (261) Show / Hide 
Range on Protein: 133-317
Range on HMM: 78-261/261
Sequence Identity: 33% (63 aa)

GPSLKILFSLMKNNLSISTICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVIHNDLKSTQLYLIDFKYARKYKHKN-GQLVRYNENNRIMNKIFCNKFSSI
||||  ||   .   |. |. | .  |.  .| ||. | .|| .||   ..    .    |.|||  |..|.  .  | . | ||  .       .. ||
GPSLEDLFNYCHRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTG---TARYASI

GTHLGITPSRKDDLESLGYILIYLTRKGNLFGSKHFKTREEKLKYYEEQKLSLIPETLGD-LPAEFVNYLNYIKSMNIMDHPEYDVW
 ||.||  ||.||||||||.|.|  |    .      |. .|     |.|.|   .|| . .| ||..|.|| ...   |.|.|   
NTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase n922.AA CK1-A 133-317 32 2.1e-28 97.36 In-house 78-261 (261) Show / Hide 
Range on Protein: 133-317
Range on HMM: 78-261/261
Sequence Identity: 32% (60 aa)

GPSLKILFSLMKNNLSISTICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVIHNDLKSTQLYLIDFKYARKYK-HKNGQLVRYNENNRIMNKIFCNKFSSI
||||  || . |   .. |. |    |.  .| .|  | .|| .||   ..  .    .|.||||  |.||. ..  | . | |   ..  .   .. ||
GPSLEDLFNFCKRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTA---RYASI

GTHLGITPSRKDDLESLGYILIYLTRKGNLFGSKHFKTREEKLKYYEEQKLSLIPETLGD-LPAEFVNYLNYIKSMNIMDHPEYDVW
  ||||  ||.||.||.||...|  |.   .   . .|.. |     |.|.|   | |    ||||  |.||....   ..|.|   
NAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase n922.AA CK1-Unclassified 228-257 63 4.9e-16 43.85 In-house 182-211 (244) Show / Hide 
Range on Protein: 228-257
Range on HMM: 182-211/244
Sequence Identity: 63% (19 aa)

FSSIGTHLGITPSRKDDLESLGYILIYLTR
..|| .||||  ||.||||||||.|||. .
YASINAHLGIEQSRRDDLESLGYVLIYFLK
Kinase n922.AA CK1-Unclassified 133-209 31 2.9e-14 38.53 In-house 87-166 (244) Show / Hide 
Range on Protein: 133-209
Range on HMM: 87-166/244
Sequence Identity: 31% (25 aa)

GPSLKILFSLMKNNLSISTICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVIH-NDLKSTQLYLIDFKYARKYK--HKNGQ
||||  || ...  .|. |. | .  |.  .| .|. |..|| .||  ...     ...|.|.||| .. .|.   |.|.
GPSLEDLFNMCNRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGK
Kinase n922.AA CK1 228-257 63 5.7e-13 41.18 In-house 182-211 (271) Show / Hide 
Range on Protein: 228-257
Range on HMM: 182-211/271
Sequence Identity: 63% (19 aa)

FSSIGTHLGITPSRKDDLESLGYILIYLTR
. || |||||  ||.||.|||||.|.|. |
YASINTHLGIEQSRRDDMESLGYVLMYFLR
Kinase n922.AA CK1 133-216 33 8e-13 40.66 In-house 88-173 (271) Show / Hide 
Range on Protein: 133-216
Range on HMM: 88-173/271
Sequence Identity: 33% (29 aa)

GPSLKILFSLMKNNLSISTICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVIHN-DLKSTQLYLIDFKYARKYK-HKNGQLVRYNEN
||||  || ...  .|. |..| .  |.  .| .|. |..|| .||  ...     ...|.|.|||  | .|.  |..| . | ||
GPSLEDLFNFCNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYREN
Kinase n922.AA CK1-G 230-317 33 9.3e-11 32.6 In-house 176-266 (266) Show / Hide 
Range on Protein: 230-317
Range on HMM: 176-266/266
Sequence Identity: 33% (31 aa)

SIGTHLGITPSRKDDLESLGYILIYLTRKGNLFGSKHFKTREEKLKYYE--EQKLSLIPETLGDL---PAEFVNYLNYIKSMNIMDHPEYDVW
|| ||||   || ||.|.|| . .|  | | |      |    |..|    ..| .. .| | .    | .|  || |. ...  ..| ||  
SINTHLGREQSRRDDMEALGHMFMYFLR-GSLPW-QGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase n922.AA TTBKL 133-208 32 4.4e-10 30.3 In-house 83-164 (288) Show / Hide 
Range on Protein: 133-208
Range on HMM: 83-164/288
Sequence Identity: 32% (27 aa)

GPSLKILFSLMKNN--LSISTICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVIHND----LKSTQLYLIDFKYARKYKHKNG
||.|. | . |.|.  .| .|.   ||  | .| ..|.. ..|| .||  .....     ...  .|||||  ||.|. |.|
GPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDG
Kinase n922.AA TTBK 148-209 34 7.6e-08 23.85 In-house 95-157 (257) Show / Hide 
Range on Protein: 148-209
Range on HMM: 95-157/257
Sequence Identity: 34% (22 aa)

SISTICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVI-HNDLKSTQLYLIDFKYARKYKHKNGQ
|.||    |. .|. .|.||||   ||  ||    .  |  .  . |..||  ||.|    |.
SLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGE
Kinase n922.AA CK1-G 133-203 32 2.8e-07 20.61 In-house 79-151 (266) Show / Hide 
Range on Protein: 133-203
Range on HMM: 79-151/266
Sequence Identity: 32% (24 aa)

GPSLKILFSLMKNNLSISTICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVI--HNDLKSTQLYLIDFKYARKY
||||  || .     |. |.||  | |.. .|..|| . . |  ||    |      .   ...|||  |..|
GPSLEDLFDWCDRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQY
Kinase n922.AA CK1 279-315 38 3.2e-07 21.14 In-house 233-271 (271) Show / Hide 
Range on Protein: 279-315
Range on HMM: 233-271/271
Sequence Identity: 38% (15 aa)

EQKLSLIPETL--GDLPAEFVNYLNYIKSMNIMDHPEYD
| |.|. .|.|  | .|.||..||||.....  . | |.
EKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase n922.AA CK1-Unique 133-255 23 6.4e-07 20.05 In-house 93-223 (337) Show / Hide 
Range on Protein: 133-255
Range on HMM: 93-223/337
Sequence Identity: 23% (32 aa)

GPSLKILFSLMKN-NLSIS------TICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVIHNDL--KSTQLYLIDFKYARK--YKHKNGQLVRYNENNRIMN
|||.  .. .|||     .      ..  .| . |||.|  | .   ||..||  ..       .   .| .|.   |.     .|.|.        |  
GPSMEECCMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQI---RQPRPITP

KIFCNKFSSIGTHLGITPSRKDDLESLGYILIYL
 . | .....  |.    .|.||.||. | |. |
FRGCKDYCPCSCHQCREHGRRDDMESWFYMLYHL
Kinase n922.AA Ciliate-E1 40-209 14 1e-06 18.34 In-house 1-165 (202) Show / Hide 
Range on Protein: 40-209
Range on HMM: 1-165/202
Sequence Identity: 14% (26 aa)

IYKGQFHNTYKGFNKINKQPVIIKMSNQYYDHISNENKMVKLLKEDSVCQTLVFKICF---LNFQK-KQANKNTALFQEVKQTIFTVFSINRITESYGPS
| .| |.  .|.... |.. ....   .. . .. ...  .. ....... . ....    ....| .|..  ...|...... .  .. .         
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNH-------NR

LKILFSLMKNNLSISTI--CMFGIAMLNVLEEIHSVNIVHRNLKPKKIVIHNDLKSTQLYLIDFKYARKYKHKNGQ
|.. .....|. . .    .   . ..  |.|.|. || ||..||..|.| |. .  .. . ||  ....| .. |
LEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-G--NYVYCDFGISKFLKNNQNQ
S_TKc n922.AA S_TKc 34-314 16 2e-06 -82.95 SMART 1-231 (231) Show / Hide 
Range on Protein: 34-314
Range on HMM: 1-231/231
Sequence Identity: 16% (51 aa)

YLIRECIYKGQFHNTYKGFNKINKQPVIIKMSNQYYDHISNENKMVKLLKEDSVCQTLVFKICFLNFQKKQANKNTALFQEVKQTIFTVFSINRITESYG
| | . | || |   ||. .|  .. | ||. .                      ...   |  |        .|   . .| |.     ..  ..|  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------------EHIRREIQILKK----HHPNIVKLYDVFQD----DHLYMVMEYCD

PSLKILFSLMKNN--------LSISTICMFGIAMLNVLEEIHSVNIVHRNLKPKKIVIHNDLKSTQLYLIDFKYARKYKHKNGQLVRYNENNRIMNKIFC
 .|  ||...|..        ..  ... .   ... || .|| .|.|| |||  | . .     .. ..||  ||..                      
GDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----------------------

NKFSSIGTH-------LGITPSR-KDDLESLGYILIYLTRKGNLFGSKHFKTREEKLKYYEEQKLSLIPETLGDLPAEFVNYLNYIKSMN--------IM
   . .||        |    .. | |  |.| ||. .     .|   . ..  .|..                 . |. . .. .  ..        ..
--TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTAEAL

D-------HPEY
        ||  
QDEWDIKCHPWF
Kinase n922.AA TTBK 289-317 37 0.000102 12.63 In-house 229-257 (257) Show / Hide 
Range on Protein: 289-317
Range on HMM: 229-257/257
Sequence Identity: 37% (11 aa)

LGDLPAEFVNYLNYIKSMNIMDHPEYDVW
| ..| ||  ... |||.|  | |.| . 
LKHCPHEFHQFMDHIKSLNYEDRPDYQLI