Gene n1190 (Tetrahymena)

n1190

Species: Tetrahymena
Alias: 1190, n1190, 445.m00010
External Links:
Annotation:

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C2

Sequence

Name Sequence Type Origin Length Description Download
n1190.AA Protein None 1454 None Fasta, JSON
n1190.NA RNA None 4365 None Fasta, JSON
n1190.kin_dom Protein Kinase Domain None 61 None Fasta, JSON

Protein domain

Protein domains of n1190.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n1190.AA Ciliate-C8 122-251 25 3.1e-18 62.17 In-house 91-238 (238) Show / Hide 
Range on Protein: 122-251
Range on HMM: 91-238/238
Sequence Identity: 25% (38 aa)

FEEEMCN--LSLLDIVLSQKPKSIELDQELKLQIVIKILDSLNYLHKQDLVHGNLKFSNILQQSK-----IFKLSDQFLNIHDQLKQSSLLSQEED--EE
.| | |    .| .    .. | ....|. |..|.| ..||.||||  . .|   | .|.| .       . ||.| |. .  .. ..| |.....    
MEMEKCQQNCNLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCD-FK-KQCDFGFASQLPKNKSHYHS

SKNIQLQRI-----ICNYSMHPPEIIQKKEPTIQSDIFT-------LGILL
.|  . . .     . |.   .||...|..  ||||||.       .|..|
KKFKGTDQYIEMYFCGNWGYFAPEVEKKQS-RIQSDIFSKKSDSYSVGLVL
Kinase n1190.AA C8 123-251 25 6.2e-16 51.89 In-house 98-226 (226) Show / Hide 
Range on Protein: 123-251
Range on HMM: 98-226/226
Sequence Identity: 25% (35 aa)

EEEMCNLSLLDIVLSQKPKSIELDQELKLQIVIKILDSLNYLHKQDLVHGNLKFSNIL----QQSK-IFKLSDQFLNIHDQLKQSSLLSQEEDEESKNIQ
| |.|.  | .. . .. |  ....| |..| |...|..||.|    .|  .|..|.|    |..  . ||.|  . . .|....    |  .  .    
EMELCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCD--FGFASQVSKNKSHIQSKKMNT----

LQRIICNYSMHPPEIIQK-----KEPTIQSDIFTLGILL
    . .     |||..|     |. .||||.| .|..|
----CGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase n1190.AA C2 122-264 25 1.4e-13 42.91 In-house 96-245 (245) Show / Hide 
Range on Protein: 122-264
Range on HMM: 96-245/245
Sequence Identity: 25% (40 aa)

FEEEMCNLSLLDIVLSQKPKSIELDQELKLQIVIKILDSLNYLHKQDLVHGNLKFSNILQQSK-----IFKLSDQFLNIHDQ---LKQSSLLSQEEDEES
.| | |   |      .. . ....|. | ...| ..|| ||||. |.||.  | ||.| |       . ||.|... .  .   ....| |. .. . .
YEQEFCQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQY-QKKCDFDFASKLKYNKSRIH

K---NIQLQRIICNYSMHPPEIIQKKEPTIQSDIFT-LGILLLQLDNIQKFNYAN
    . . | .     .   ..|.||    .||.|  .|. || |||.| ..   
FSKFKWTQQYYQHIFAPEVYQNIYKK----NSDLFSTVGYVLLELDNMQQYTICC
Kinase n1190.AA Ciliate-E2-Unclassified 120-254 16 5.1e-08 23.94 In-house 96-263 (352) Show / Hide 
Range on Protein: 120-254
Range on HMM: 96-263/352
Sequence Identity: 16% (29 aa)

IYFEEEMCNLSLLDIVLSQKPK--------------SIELDQELKL-----QIVIKILDSLNYLHKQD-LVHGNLKFSNILQQSK----IFKLSDQFLNI
||.  | |.   |   .....|              . ... .  .     ..   ||. |.|||..   .| ..| .||| ...      |..| ..  
IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGI--

HDQLKQSSLLSQEEDEES--------KNIQLQRIICNYSMH---PPEIIQKKEPT----IQSDIFTLGILLLQL
    |..   .... ...        .... ...  .. |    .||..|....     ...||..||..| ..
---SKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM
Kinase n1190.AA Ciliate-E1 131-245 16 2.7e-07 20.31 In-house 93-202 (202) Show / Hide 
Range on Protein: 131-245
Range on HMM: 93-202/202
Sequence Identity: 16% (20 aa)

LLDIVLSQKPKSIELDQELKLQIVIKILDSLNYLHKQDLVHGNLKFSNILQ-QSKIFKLSDQFLNIHDQLKQSSLLSQEEDEES-KNIQLQRIICNYSMH
| ... ... . ...... |.||.. ..| |..|| . . |...| .|||. ........        .. .|..|  ...... .. ...   ... . 
L-EYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC--------DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYN

PPEI--IQKKEPTIQSDIF
 ||   ..... ...|||.
CPEQEHNKNQKINYKSDIY
Kinase n1190.AA VRK 151-180 50 3.5e-07 19.51 In-house 133-162 (284) Show / Hide 
Range on Protein: 151-180
Range on HMM: 133-162/284
Sequence Identity: 50% (15 aa)

LQIVIKILDSLNYLHKQDLVHGNLKFSNIL
||  . .||.| |||  . |||..| .|||
LQLACRMLDVLEYLHENEYVHGDIKAANIL
S_TKc n1190.AA S_TKc 44-320 13 3.6e-07 -71.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 44-320
Range on HMM: 1-231/231
Sequence Identity: 13% (39 aa)

YTDIDYIIDTDHSLLLSAKNKF-KEFIALKLCQAHASQYGMIYSVINQIKVQNHNQFFSYIQVNDIKTFSVQNDILIIYFEEEMCNL---SLLDIVLSQK
|. .. |     .    ...|  ..  |.|             .... |..  .         | .| . |  |   .|.  |.|.    .|.|.  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

PKSIE--LDQELKLQIVIKILDSLNYLHKQDLVHGNLKFSNILQQSKIFKLSD-----QFLNIHDQLKQSSLLSQEEDEESKNIQLQRIICNYSMHPPEI
..     ..      ..  |.. |.|.|..  .|  || .|||  .   |..|     |.                            ..      .||.
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL--------------------------TTFCGTPWYMAPEV

IQKKEPTI-QSDIFTLGILLLQLDNIQKFNYANIESIEKDYEKYFSQGQIPPQLQLQSESIFYKLAMNMIKKNPSDRMNCEFYIQ-------KLML
.     .   .|.  .|..|  .   .   . ... . |                  |..    . ... .|.|..|. .    |          .
L---GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG---------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase n1190.AA Ciliate-C3 150-184 57 5.4e-07 21.45 In-house 98-132 (140) Show / Hide 
Range on Protein: 150-184
Range on HMM: 98-132/140
Sequence Identity: 57% (20 aa)

KLQIVIKILDSLNYLHKQDLVHGNLKFSNILQQSK
||||  .||  ..|||   .||| .||||||  ||
KLQISKQILQAIDYLHEHNIVHGDIKFSNILINSK
Kinase n1190.AA TBCK 151-180 43 3e-06 18.44 In-house 83-112 (346) Show / Hide 
Range on Protein: 151-180
Range on HMM: 83-112/346
Sequence Identity: 43% (13 aa)

LQIVIKILDSLNYLHKQDLVHGNLKFSNIL
| |   ||  |.|.||...||..|  .||.
LCIYYQILCGLSYMHKHHIVHRFLHPHNIY
Kinase n1190.AA CAMK-Unique 151-180 40 3e-06 16.28 In-house 160-189 (363) Show / Hide 
Range on Protein: 151-180
Range on HMM: 160-189/363
Sequence Identity: 40% (12 aa)

LQIVIKILDSLNYLHKQDLVHGNLKFSNIL
..|. ..|  ..|.|.|| ||..||  ||.
CFIMQCLLSAVAYMHSQDIVHRDLKLENIM
Kinase n1190.AA Dicty3 153-180 34 3e-06 16.52 In-house 116-144 (351) Show / Hide 
Range on Protein: 153-180
Range on HMM: 116-144/351
Sequence Identity: 34% (10 aa)

IVIKILDSLNYLHKQD-LVHGNLKFSNIL
|..... .|||.||.  ..|...|  ||.
IICDLVKTLNYIHKNCHIIHRDIKCDNIM