Gene CC1G_01467 (C.cinerea)

CC1G_01467

Species: C.cinerea
Alias: CC1G_01467
External Links:
Annotation:

Classification

Group: CMGC
Family: CLK

Sequence

Name Sequence Type Origin Length Description Download
CC1G_01467.AA Protein None 664 None Fasta, JSON
CC1G_01467.NA RNA None 1995 None Fasta, JSON
CC1G_01467.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of CC1G_01467.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CC1G_01467.AA Ciliate-E2 432-660 15 1.1e-22 74.67 In-house 118-365 (365) Show / Hide 
Range on Protein: 432-660
Range on HMM: 118-365/365
Sequence Identity: 15% (52 aa)

GMSLRDVLDIK----------ELVPLPLNQVKAFSHQILS---------------GIQYLHTQD-IIHTDITPSNVVLVQDDITCYQEYTATNEVVTKHR
|..|.| . ..          .  .. ....| .. |||.               ...||| .  ||| || |.|...                      
GGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------------------

LRSIAVKLIDLD-------------------------------GYFDWRVQCEPRYA----------AGTRGYRAPEISLGIP---------WTKGIDIF
     .|.||.                                ||.|                    .|| || ||||  | .         ... .||.
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD---------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

SFGCTLWELHSGGALFNPSDDWTKQLRIIERFAGKLSSNFFERLRIDGSPYSKEDFKLSWRHAEDRESQMIQIRRPDLR---------------------
|.|..| |. .|   |                                                     ..||   ...                     
SLGVILYEMLFGKPPF-----------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWK

-------DLLKA----CLQGDDRVRVG-VDQALQHRFY
       ||.|     .|| |   | .  .|.|.| . 
KWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CC1G_01467.AA CMGC 534-660 17 7.4e-21 64.43 In-house 288-513 (513) Show / Hide 
Range on Protein: 534-660
Range on HMM: 288-513/513
Sequence Identity: 17% (40 aa)

TRGYRAPEISLGIP----------WTKGIDIFSFGCTLWELHSG--------GALFNPSDDW----------TKQLRIIERFAGKL--------------
|| |||||| || .          .|..||. |.|| . |.  |          || ....             ||  | .  |.               
TRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFC

--SSNFFERLR---------------------IDGSPYSKEDFKLSWRHAEDRESQMIQIRR----------------------------------PDLR
  . ......                      ...  | .  ... |..  . ....  ...                                  |...
KHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAI

DLLKACLQGDDRVRVGVDQALQHRFY
|||| .|| |   |  ..||||| . 
DLLKKMLQYDPDKRITAEQALQHPYF
S_TKc CC1G_01467.AA S_TKc 359-660 16 1.7e-18 68.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 359-660
Range on HMM: 1-231/231
Sequence Identity: 16% (55 aa)

FHK----------CVWTGTDMRSRERVVVKAIALADDSEHEVTRLQRLTRCLDHAKAKGLTLFVDILASEVTNVYSVVCLTAHG--MSLRDVLDIKEL--
...          .|. ... .. ..| .| |   .. . |.  |..        . . .  . |.  .   . . .|   . |   .|.|... .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--------HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--VPLPLNQVKAFSHQILSGIQYLHTQDIIHTDITPSNVVLVQDDITCYQEYTATNEVVTKHRLRSIAVKLIDLDGYFDWRVQCEPRYAAGTRGYRAPEI
  .|.|  ... . .||.....|.| . ||| |. |.|. | .                         .|..|    |    |   .   ||. |.|||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------------------------HIKICD----FGLARQL--TTFCGTPWYMAPEV

SLGIPWTK-GIDIFSFGCTLWELHSGGALFNPSDDWTKQLRIIERFAGKLSSNFFERLRIDGSPYSKEDFKLSWRHAEDRESQMIQIRRPDLRDLLKACL
    ...|  .|. |.||.|.|. .|  .|    .  . ...|                                              |...|... ||
L---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--------------------------------------------SPEAKDFIRKCL

QGDDRVRVGVDQALQ-------HRFY
| | . | .. .|||       | . 
QKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CC1G_01467.AA Pkinase 532-660 23 1.6e-15 55.93 Pfam 172-293 (293) Show / Hide 
Range on Protein: 532-660
Range on HMM: 172-293/293
Sequence Identity: 23% (30 aa)

AGTRGYRAPEISL-GIPWTKGIDIFSFGCTLWELHSGGALFNPSDDWTKQLRIIERFAGKLSSNFFERLRIDGSPYSKEDFKLSWRHAEDRESQMIQIRR
.||..|.|||. . | .... .|..|.||.|.|. .|  .|  .. |.. .. ..... ...  . .    . |..  . |.  | |  . ..       
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWS

PDLRDLLKACLQGDDRVRVGVDQALQHRFY
....|..| ||. |   | . .|.||| . 
EECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CC1G_01467.AA CMGC 432-486 20 3.8e-14 41.96 In-house 138-220 (513) Show / Hide 
Range on Protein: 432-486
Range on HMM: 138-220/513
Sequence Identity: 20% (17 aa)

GMSLRDVLDIKE-------LVPLPLNQ------------VKAFS------HQILSGIQ--YLHTQD--IIHTDITPSNVVLVQD
...| .... .         .||.  .            .| |.      .||| |.   |.| ..  |||.|. |.|. . ..
DHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHN
Kinase CC1G_01467.AA DYRK 537-660 25 7.4e-13 44.63 In-house 170-320 (320) Show / Hide 
Range on Protein: 537-660
Range on HMM: 170-320/320
Sequence Identity: 25% (39 aa)

YRAPEISLGIPWTKGIDIFSFGCTLWELHSGGALFNPSDDWTKQLRIIERFAGKLSSNFFERLR------------------IDGSPY-SKEDFKLSWRH
|||||. ||.|  . ||. |.||.| ||. |  || | ..   ||. |  . |. ......  |                   ... . ..... ..   
YRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLF-PGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDCFMYCECDEWTKQNKITDHYMTPKCHP

AEDRESQMIQIRR----------PDLRDLLKACLQGDDRVRVGVDQALQHRFY
  . .. ... ||           .. |..| ||| | . |.   ||||| . 
TKR-GQRRPPGRRNWDPRHQCDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase CC1G_01467.AA ERK7 534-660 33 1.3e-11 35.69 In-house 169-292 (292) Show / Hide 
Range on Protein: 534-660
Range on HMM: 169-292/292
Sequence Identity: 33% (43 aa)

TRGYRAPEISLGIPW-TKGIDIFSFGCTLWELHSGGALFNPSDDWTKQLRIIERFAGKLSSNFFERLRIDGSPYSKEDFKLSWRHAEDRESQMIQIRRPD
|| |||||| ||  . |||.|  | || | |.  | ..| |      |.  | .  .| .    | .   || |.    .   .. .   .||..   .|
TRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRGKPMF-PGTSTMNQIEKILETIPKPTQEDIEAI---GSHYAWNMLEQMNQQKRKTLDQMMPQCCDD

LRDLLKACLQGDDRVRVGVDQALQHRFY
  ||||. |.   . |. ..|||||.. 
AIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase CC1G_01467.AA CLK 534-571 52 1.3e-11 30.32 In-house 210-247 (350) Show / Hide 
Range on Protein: 534-571
Range on HMM: 210-247/350
Sequence Identity: 52% (20 aa)

TRGYRAPEISLGIPWTKGIDIFSFGCTLWELHSGGALF
|| |||||. || .|    |. |.|| | || .|  ||
TRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLF
Kinase CC1G_01467.AA CLK 432-515 18 5.5e-11 28.45 In-house 90-190 (350) Show / Hide 
Range on Protein: 432-515
Range on HMM: 90-190/350
Sequence Identity: 18% (19 aa)

GMSLRDVLDIKE------LVPLPLNQVKAFSHQILSGIQYLHTQDIIHTDITPSNVVLVQD---DITCYQEYTATNE--------VVTKHRLRSIAVKLI
| |. |...           |.|.........|... .. ||   ..|||  | |  .|.     . |   |. ..         |    .. .  ...|
GLSIYDFMKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKINKKSNNCVCHYWHVKNTHICVI

D
|
D
Kinase CC1G_01467.AA DYRK2 537-584 41 5.7e-11 31.58 In-house 168-214 (318) Show / Hide 
Range on Protein: 537-584
Range on HMM: 168-214/318
Sequence Identity: 41% (20 aa)

YRAPEISLGIPWTKGIDIFSFGCTLWELHSGGALFNPSDDWTKQLRII
|||||. ||..  . ||. ||||.. || .|  || | ..   |.  .
YRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLF-PGENENDQFACM
Kinase CC1G_01467.AA SRPK 534-573 42 8.1e-11 22.53 In-house 415-454 (554) Show / Hide 
Range on Protein: 534-573
Range on HMM: 415-454/554
Sequence Identity: 42% (17 aa)

TRGYRAPEISLGIPWTKGIDIFSFGCTLWELHSGGALFNP
|| ||.||  .|...  . ||.|. | ..||  |  || |
TRQYRSPEVIIGAGYNTPADIWSTACMAFELATGDYLFEP
Kinase CC1G_01467.AA SRPK 447-483 50 3.1e-10 21.0 In-house 126-163 (554) Show / Hide 
Range on Protein: 447-483
Range on HMM: 126-163/554
Sequence Identity: 50% (19 aa)

LPLNQVKAFSHQILSGIQYLHTQ-DIIHTDITPSNVVL
.|. .||  . |.| |  |||.  .|||||| | || |
MPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENVLL
Kinase CC1G_01467.AA MOS 523-562 42 1.5e-08 24.27 In-house 190-229 (299) Show / Hide 
Range on Protein: 523-562
Range on HMM: 190-229/299
Sequence Identity: 42% (17 aa)

RVQCEPRYAAGTRGYRAPEISLGIPWTKGIDIFSFGCTLW
. . .| |. || .|.|||.  |   |   ||.||| |.|
CAWTNPHYLKGTCTYMAPELLCGDTPTPKADIYSFGITMW
Kinase CC1G_01467.AA DYRK2 449-485 43 2.4e-08 22.91 In-house 101-137 (318) Show / Hide 
Range on Protein: 449-485
Range on HMM: 101-137/318
Sequence Identity: 43% (16 aa)

LNQVKAFSHQILSGIQYLHTQDIIHTDITPSNVVLVQ
|. | .| |.|| ... ||  .||| |  | |..| |
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQ
Kinase CC1G_01467.AA TKL 430-486 23 2.6e-08 26.07 In-house 120-176 (364) Show / Hide 
Range on Protein: 430-486
Range on HMM: 120-176/364
Sequence Identity: 23% (15 aa)

AHGMSLRDVLDIKELVPLPLNQVKAFSHQILSGIQYLHTQD--------IIHTDITPSNVVLVQD
..| ||...|         ..|   ....| .|..|||...        ||| |....|. . ..
CPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDEN
Kinase CC1G_01467.AA Pkinase 433-515 22 9.1e-08 28.54 Pfam 89-155 (293) Show / Hide 
Range on Protein: 433-515
Range on HMM: 89-155/293
Sequence Identity: 22% (19 aa)

MSLRDVLDIKELVPL--PLNQVKAFSHQILSGIQYLHTQDIIHTDITPSNVVLVQDDITCYQEYTATNEVVTKHRLRSIAVKLID
|.| |..  ..  ..  . ...| .  |||.|..|.| . ||| |. |.|. ..... ..                    ||..|
MDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA------------------CVKICD
Kinase CC1G_01467.AA TKL 533-567 25 1.3e-07 23.49 In-house 235-285 (364) Show / Hide 
Range on Protein: 533-567
Range on HMM: 235-285/364
Sequence Identity: 25% (13 aa)

GTRGYRAPEISLGI----------------PWTKGIDIFSFGCTLWELHSG
|| .. |||.  |                 . .. .|..|||  |||. ..
GTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTR
Kinase CC1G_01467.AA CDKL 447-489 27 2e-07 21.45 In-house 95-138 (286) Show / Hide 
Range on Protein: 447-489
Range on HMM: 95-138/286
Sequence Identity: 27% (12 aa)

LPLNQVKAFSHQILSGIQYLHTQDIIHTDITPSNVVLV-QDDIT
.. ..|.    |||..|...| ...|| || | |  .  .....
VDEHVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQV
Kinase CC1G_01467.AA DYRK 447-485 42 4.7e-07 22.7 In-house 100-139 (320) Show / Hide 
Range on Protein: 447-485
Range on HMM: 100-139/320
Sequence Identity: 42% (17 aa)

LPLNQVKAFSHQILSGIQYLHTQ-DIIHTDITPSNVVLVQ
..|| |. | .||| .. .||.  .||| |. | |..|.|
FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQ
Kinase CC1G_01467.AA MOS 455-490 35 3e-06 16.36 In-house 119-157 (299) Show / Hide 
Range on Protein: 455-490
Range on HMM: 119-157/299
Sequence Identity: 35% (14 aa)

FSHQILSGIQYLHTQDIIHTDITPSNVVLVQD----DITC
.|  .....||.| | |.| |. | | ..| .     |||
YSLDVVNALQYCHHQNILHLDVKPAN-IIVDEGTKSSITC
TyrKc CC1G_01467.AA TyrKc 349-659 14 6e-06 -126.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 349-659
Range on HMM: 1-280/280
Sequence Identity: 14% (51 aa)

VKFTGSI-SCAF---HKCVWTGTDMRSRERVVVKAIALADDSEHEVTRLQRLTRCLDHA--KAKG-LTLFVDILAS-----EVTNVYSVVCLTAHGMSLR
...   . ..||   .|..|.       . | || .         .  . |  | . .   . .  . |.  .. .     ..  .. |. . .|| .|.
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG-DLK

DVLDIKELVPLPLNQVKAFSHQILSGIQYLHTQDIIHTDITPSNVVLVQDDITCYQEYTATNEVVTKHRLRSIAVKL------IDLDGY-FDWRVQCEPR
| |  ..   |.. .   |..|| .| .||| . .|| |.   |. .  .                        ||        |.. .        .  
DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----------------------TVKISDFGLSRDIYDDDQQG--ESKDY

YAA----GTRG-----YRAPEISLGIPWTKGIDIFSFGCTLWELHSGGALFNPS-----DDWTKQLRIIERF----AGKL----SSNFFERLRIDGSPYS
| .    |...       |||       |   |..||| ..||. . |.   |       ...  .. ...       .     |               
YRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------

KEDFKLSWRHAEDRESQMIQIRRPDLRDLLKACLQGDDRVRVGVDQALQHRF
               .    .  ... .. | | . |   |    .   ..|
---------------F---VCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase CC1G_01467.AA ERK7 458-483 46 2.8e-05 13.66 In-house 108-133 (292) Show / Hide 
Range on Protein: 458-483
Range on HMM: 108-133/292
Sequence Identity: 46% (12 aa)

QILSGIQYLHTQDIIHTDITPSNVVL
|.|  |.|.|  ..|| |. |||. |
QLLRAIKYMHSGNVIHRDLKPSNILL
Kinase CC1G_01467.AA CDKL 534-571 41 9.3e-05 12.19 In-house 162-200 (286) Show / Hide 
Range on Protein: 534-571
Range on HMM: 162-200/286
Sequence Identity: 41% (16 aa)

TRGYRAPEISLG-IPWTKGIDIFSFGCTLWELHSGGALF
|| |||||  .|     | .|| . || . |. .| .|.
TRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLW
Kinase CC1G_01467.AA CDKL 635-660 30 0.000348 10.21 In-house 261-286 (286) Show / Hide 
Range on Protein: 635-660
Range on HMM: 261-286/286
Sequence Identity: 30% (8 aa)

DLLKACLQGDDRVRVGVDQALQHRFY
|..|.||. | . |. ..|...| . 
DFMKKCLHMDPDERMTCEQLMHHPYF
Kinase CC1G_01467.AA CLK 635-660 38 0.001572 5.65 In-house 325-350 (350) Show / Hide 
Range on Protein: 635-660
Range on HMM: 325-350/350
Sequence Identity: 38% (10 aa)

DLLKACLQGDDRVRVGVDQALQHRFY
||.. .|  |   |.  ..||||.| 
DLIRKMLEYDPSKRITCKDALQHPFF
Kinase CC1G_01467.AA DYRK2 631-660 30 0.021474 3.22 In-house 289-318 (318) Show / Hide 
Range on Protein: 631-660
Range on HMM: 289-318/318
Sequence Identity: 30% (9 aa)

PDLRDLLKACLQGDDRVRVGVDQALQHRFY
... | .| |.. |   |   .|||.| . 
ENFIDFIKRCFEWDPSERMTPSQALKHPWI