Gene CC1G_10260 (C.cinerea)

CC1G_10260

Species: C.cinerea
Alias: CC1G_10260
External Links:
Annotation:

Classification

Group: CMGC
Family: SRPK

Sequence

Name Sequence Type Origin Length Description Download
CC1G_10260.AA Protein None 709 None Fasta, JSON
CC1G_10260.NA RNA None 2130 None Fasta, JSON
CC1G_10260.kin_dom Protein Kinase Domain None 642 None Fasta, JSON

Protein domain

Protein domains of CC1G_10260.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CC1G_10260.AA SRPK 534-698 55 6.4e-108 278.58 In-house 392-554 (554) Show / Hide 
Range on Protein: 534-698
Range on HMM: 392-554/554
Sequence Identity: 55% (91 aa)

ISIKIADLGNATPSKKHFTEDIQTRQYRAPEAIVGRKDWDTRADVWSVACVVFELLTAEYLFDPQGQGELFTKDDDHMAQIIELLGDFPLDVKMGGKYSR
| |||||||||    .||||||||||||.||.|.| . ..| ||.||.|| .|||.|  |||.|  .|| ...|||| |.||||.|..|  .   |||||
IKIKIADLGNACWVHHHFTEDIQTRQYRSPEVIIGAG-YNTPADIWSTACMAFELATGDYLFEPH-SGEDYSRDDDHIAHIIELCGKIPWHFALSGKYSR

ELFDHTGALRYIRTLKPWPLKRVMIEKYLYSEEDSDALCAFLEPMLKADMRERAHARDMLDHPWL
| |.. | || | .||||||..| |||| .|.|.. .  .|| |||. . . || |...| ||||
EFFNKKGELRHIPKLKPWPLMNVLIEKYEWSHEEAKQFEDFLMPMLHYNPEKRATAKECLQHPWL
Kinase CC1G_10260.AA SRPK 57-196 49 7.2e-102 262.63 In-house 1-161 (554) Show / Hide 
Range on Protein: 57-196
Range on HMM: 1-161/554
Sequence Identity: 49% (79 aa)

YRVVRKLGWGHFSTVWLVKDSQSGVHSALKVVKSAGRYAETARDEIKLLSRVASVSPD---------------------HPGRAHIVSFLDSFSHQGPES
|.|.||||||||||||| .| |   . |.|.||||  | ||| ||||||..|.. .|.                      |.| |.| .||.| | ||  
YHVIRKLGWGHFSTVWLCWDMQYDRYVAMKIVKSAPHYTETAVDEIKLLQCVRKHDPNPQWMHFLKEYYEDYKRDCKEFDPNRCHVVQLLDHFKHRGPNG

SHICIVFEPLGENLLALIERNKKKGVPKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENI
 |.| ||| ||.|||..|... ..|.| ..||.||.||| || |||..|.  ||||||||.
NHYCMVFEVLGHNLLKWIKHYNYQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENV
Kinase CC1G_10260.AA CMGC 57-698 10 1e-88 291.55 In-house 1-513 (513) Show / Hide 
Range on Protein: 57-698
Range on HMM: 1-513/513
Sequence Identity: 10% (91 aa)

YRVVRKLGWGHFSTVWLVKD--------------SQSGVHSALKVVKSAGRYAETAR-------------DEIKLLSRVA----------SVSPDHPGRA
| ...|.|.|....|.  .|               ... . |.| .|..  | |.|.             .|||.| ..              ||.. . 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRD-DPDNKHHN

HIVSFLDSFSHQGPESS-------------HICIVFEPLGENLLALIERNK--------------------------KKGVPKALVKIIAKQVLLGLQ--
.||. .|.| | .....             |...||| .. .|. .|..|.                          .|  .  ... ...|.| ||   
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

YLHDEC-DLVHTDIKPENICFTKSTCL--------EVTSVRQTLEELDELTRSGIPIQMKGKEKEPEGLSAGSSPLKPSSWIEQASSLSSSYKSKGSPFK
|.|  . . .|.|.||||| ... . |        |                                                                
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSE----------------------------------------------------------------

SSKPRSSNRHGHSHSQSGAPWQDPGVASPAPAVLVNAVASADGQETSQTAFNSLRTSSSSTSTITIAHSESSSTTATATQPSPTGTPLGPRKTKTMSIIN
                                                                                                    
----------------------------------------------------------------------------------------------------

GVSKLISDTSTMLSTGLHPTSETKPNTNTTNRTPQSGETNVTTNHVSLLTQTAPTRISANVEPLRTTTTRPSPPQHISQLSAHMHSEPCPSLPSHDSVLS
                                                                                                    
----------------------------------------------------------------------------------------------------

SHFPSETSRPNFTTVSTAIAQRLVFGTSSSPAPPPPTPVDGPVFGSFPISPPPPFTSQFPNPPPIS--------IKIADLGNATPSKKH-----------
                                                                 .        .||.| |.|.   .|           
---------------------------------------------------------------D-WNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQS

-------------FTEDIQTRQYRAPEAIVGR---------KDWDTRADVWSVACVVFELLTA--------EYLFDPQGQ-----GELFTKDDDHMAQII
             .|....|| ||||| ..|          ....|  |.|||.|. .|..|         ..|| ..       .   ... |....|.
FKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDK-NGKSHIDQLFKIF

ELLGDFPLDVKMGGK-------YSRELFDHTGALRYIRTLK-------------------------PWPLKRVMIEKYLYSEE-----------------
..|| ..  .   ||       ...| ..... ..|. ..|                         ||. ..   ...  . .                 
KVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEE

---------------DSDALCAFLEPMLKADMRERAHARDMLDHPWL
               ... .  .|. ||. |  .|  | . |.||..
KFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CC1G_10260.AA CLK 57-698 15 4e-61 181.71 In-house 1-350 (350) Show / Hide 
Range on Protein: 57-698
Range on HMM: 1-350/350
Sequence Identity: 15% (104 aa)

YRVVRKLGWGHFSTVWLVKDSQSG-VHSALKVVKSAGRYAETARDEIK-LLSRVASV-SPDHPGRAHIVSFLDSFSH-QGPESSHICIVFEPLGENLLAL
| .| .|| | |..|  ..|...|  . |||.......| | |. ||.  .  ..   .|.   . |..  .|.| .  |    ||||||| .| ..  .
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHG----HICIVFELYGLSIYDF

IERNK------KKGVPKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENICFTKS-----TCLEVTSVRQTLEELDELTRSGIPIQMKGKEKEPEGLSAG
.  |.       .. | . .. .|.| .  .. |||   |.||| |||||||..|      |   . ... ..                           
MKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHD-MKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKIN---------------------------

SSPLKPSSWIEQASSLSSSYKSKGSPFKSSKPRSSNRHGHSHSQSGAPWQDPGVASPAPAVLVNAVASADGQETSQTAFNSLRTSSSSTSTITIAHSESS
                                                                                                    
----------------------------------------------------------------------------------------------------

STTATATQPSPTGTPLGPRKTKTMSIINGVSKLISDTSTMLSTGLHPTSETKPNTNTTNRTPQSGETNVTTNHVSLLTQTAPTRISANVEPLRTTTTRPS
                                                                                                    
----------------------------------------------------------------------------------------------------

PPQHISQLSAHMHSEPCPSLPSHDSVLSSHFPSETSRPNFTTVSTAIAQRLVFGTSSSPAPPPPTPVDGPVFGSFPISPPPPFTS----QFPNPP-PISI
                                                                                   .|    ..  ..    |
----------------------------------------------------------------------------------KKSNNCVCHYWHVKNTHI

KIADLGNAT---PSKKHFTEDIQTRQYRAPEAIVGRKDWDTRADVWSVACVVFELLTAEYLFDPQGQGELFTKDD-DHMAQIIELLG-DFPLDV--KM--
.. | |.||     . | .. ..||.||||| | |   | .. ||||..|. ||| | . ||.        | |  .|.| . ...| ..|     ..  
CVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLG-WSQPCDVWSIGCILFELYTGFTLFQ--------THDNREHLAMMERIMGMPIPQWMIQRTRR

---GGKYS---RELFD-HTGALRYIRTLKPWPLKRVMIEKYLYSEEDSDALCAFLEPMLKADMRERAHARDMLDHPWL
     ||    |...| |. . || .  .. |||. |    .. ... . |   .. ||  |   |  ..| |.||. 
FKVKQKYFYHNRLDWDWHNSDGRYVME-NCKPLKQYM----DCKDPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase CC1G_10260.AA S_TKc 57-698 10 6.2e-43 149.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 57-698
Range on HMM: 1-231/231
Sequence Identity: 10% (67 aa)

YRVVRKLGWGHFSTVWLVKDSQSGVHSALKVVKSAGRYAETARDEIKLLSRVASVSPDHPGRAHIVSFLDSFSHQGPESSHICIVFEPLGE---NLLALI
|...||.| | |..|.....  .| . |.|..|      |..| ||..|..      .||   .|| ..|.| .     .|...|.| ..    .|. .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK------HHP---NIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYI

ERNKKKG----VPKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENICFTKSTCLEVT---SVRQTLEELDELTRSGIPIQMKGKEKEPEGLSAGSSPLK
......|     |   .. ...|....|.|.|.    .| |.||||| ...  .. ..   . ||                                   
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL----------------------------------

PSSWIEQASSLSSSYKSKGSPFKSSKPRSSNRHGHSHSQSGAPWQDPGVASPAPAVLVNAVASADGQETSQTAFNSLRTSSSSTSTITIAHSESSSTTAT
                                                                                                    
----------------------------------------------------------------------------------------------------

ATQPSPTGTPLGPRKTKTMSIINGVSKLISDTSTMLSTGLHPTSETKPNTNTTNRTPQSGETNVTTNHVSLLTQTAPTRISANVEPLRTTTTRPSPPQHI
                                                                                                    
----------------------------------------------------------------------------------------------------

SQLSAHMHSEPCPSLPSHDSVLSSHFPSETSRPNFTTVSTAIAQRLVFGTSSSPAPPPPTPVDGPVFGSFPISPPPPFTSQFPNPPPISIKIADLGNATP
                                                                                                    
----------------------------------------------------------------------------------------------------

SKKHFTEDIQTRQYRAPEAIVGRKDWDT-RADVWSVACVVFELLTAEYLFDPQGQGELFTKDDDHMAQIIELLGDFPLDVKMGGKYSRELFDHTGALRYI
     |  . |. |.||| .     ... ..|.||. |...|.|. . .|.             .|.......|                          
-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP-------------QMQMMFKKIG--------------------------

RTLKPWPLKRVMIEKYLYSEEDSDALCAFLEPMLKADMRERAHARDMLD-------HPWL
                      |. .. |.. .|. | ..|  | . |        |||.
----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CC1G_10260.AA DYRK 57-196 32 1.5e-31 111.18 In-house 1-135 (320) Show / Hide 
Range on Protein: 57-196
Range on HMM: 1-135/320
Sequence Identity: 32% (46 aa)

YRVVRKLGWGHFSTVWLVKDSQSGVHSALKVVKSAGRYAETARDEIKLLSRVASVSPDHPGRAHIVSFLDSFSHQGPESSHICIVFEPLGENLLALIERN
|...  .| | |. |  ..| . . . |.|....  |.. .| .|||.|..      |   ..|.| ..|.| |..    | |||||.|  ||  .. .|
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ--DPDDKYHCVHMYDYFYHRN----HLCIVFELLSMNLYEFLKNN

KKKGV-PKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENI
...|. .  ||. .|.|.|..| .|| . ...| |.|||||
HFQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENI
Kinase CC1G_10260.AA DYRK2 57-196 31 3.3e-22 68.74 In-house 1-133 (318) Show / Hide 
Range on Protein: 57-196
Range on HMM: 1-133/318
Sequence Identity: 31% (44 aa)

YRVVRKLGWGHFSTVWLVKDSQSGVHSALKVVKSAGRYAETARDEIKLLSRVASVSPDHPGRAHIVSFLDSFSHQGPESSHICIVFEPLGENLLALIERN
| ..  .| | |  |  . |   . | |.|..    |....|  ||. |..  .  .|.   . .|  ||.|   .    |.||.|| |. ||  .| .|
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDN--TMNCVHMLDYFYFRN----HHCITFELLSMNLYEYIKKN

KKKGVPKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENI
...|   .||   |...| .|. || . ...| | |||||
HFQGFSLQLVRRFAHSILQCLRFLHKN-NIIHCDLKPENI
Kinase CC1G_10260.AA Pkinase 57-196 26 7.8e-22 78.28 Pfam 1-139 (293) Show / Hide 
Range on Protein: 57-196
Range on HMM: 1-139/293
Sequence Identity: 26% (40 aa)

YRVVRKLGWGHFSTVWLVKDSQSGVHSALKVVKSAGRYAETARD-----EIKLLSRVASVSPDHPGRAHIVSFLDSFSHQGPESSHICIVFEPLGE----
|...||.| | |..|.. ..  .|   |.|..|  ..  .  .      ||... |. .    ||   .|| ..|.|      ..||..|.| ..     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N----HP---NIVRLYDWFED----KDHIYMVMEYCEGGLYV

-NLLALIERNKKKGV--PKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENI
  | ..|.. .....  .   .| ...|.| ||.|.|. .  .| |.|||||
MDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENI
Kinase CC1G_10260.AA WEE 148-594 7 3e-20 64.7 In-house 91-235 (297) Show / Hide 
Range on Protein: 148-594
Range on HMM: 91-235/297
Sequence Identity: 7% (36 aa)

N--LLALIERNKKKGV--PKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENICFTKST-CLEVTSVRQTLEELDELTRSGIPIQMKGKEKEPEGLSAGS
.  |...|. .....   | .... |  ....||...|..|..|| ||||||| ..|   | ..  .                                 
SNLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIV-NN--------------------------------

SPLKPSSWIEQASSLSSSYKSKGSPFKSSKPRSSNRHGHSHSQSGAPWQDPGVASPAPAVLVNAVASADGQETSQTAFNSLRTSSSSTSTITIAHSESSS
                                                                                                    
----------------------------------------------------------------------------------------------------

TTATATQPSPTGTPLGPRKTKTMSIINGVSKLISDTSTMLSTGLHPTSETKPNTNTTNRTPQSGETNVTTNHVSLLTQTAPTRISANVEPLRTTTTRPSP
                                                                                                    
----------------------------------------------------------------------------------------------------

PQHISQLSAHMHSEPCPSLPSHDSVLSSHFPSETSRPNFTTVSTAIAQRLVFGTSSSPAPPPPTPVDGPVFGSFPISPPPPFTSQFPNPPP---------
                                                                                          .         
------------------------------------------------------------------------------------------DQQNNNDWWF

-ISIKIADLGNATPSK--KHFTEDIQ--TRQYRAPEAIVG--RKDWDTRADVWSVACVVFELLTAEYL
 . .||.|.| .|  .   . ....|   . | ||| . |  .   .. ||. | .....|| ... |
NMMCKIGDFGHVTDMNSNNNNPHQEQEGDSRYMAPEILQGYYHYTHLYKADIFSLGITIYELACNMDL
Kinase CC1G_10260.AA HIPK 57-196 33 3.2e-19 56.72 In-house 1-132 (329) Show / Hide 
Range on Protein: 57-196
Range on HMM: 1-132/329
Sequence Identity: 33% (47 aa)

YRVVRKLGWGHFSTVWLVKDSQ--SGVHSALKVVKSAGRYAETARDEIKLLSRVASVSPDHPGRAHIVSFLDSFSHQGPESSHICIVFEPLGENLLALIE
| |.  || | |  |  ||  .   .   |.|. |    ||   . |...|... . ..|    .|.| ... | |.    .|.|.||| |  ||     
YEVLEFLGRGTFGQV--VKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADE---YHFVRAYECFHHK----NHTCLVFEMLEQNLYDFQK

RNKKKGVPKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENI
 ||    |   .. | .|||  |  |  |  |.| |.|||||
QNKFMPLPLKHIRPILQQVLTALMKLK-ELGLIHADLKPENI
Kinase CC1G_10260.AA DYRK1 57-196 29 1.1e-15 51.09 In-house 1-135 (321) Show / Hide 
Range on Protein: 57-196
Range on HMM: 1-135/321
Sequence Identity: 29% (42 aa)

YRVVRKLGWGHFSTVWLVKDSQSGVHSALKVVKSAGRYAETARDEIKLLSRVASVSPDHPGRAHIVSFLDSFSHQGPESSHICIVFEPLGENLLALIERN
| .   .| | |  |    |.|   . |.|..|    . . |. ||.||  .    ...  . .||     | .      |.|.||| |  ||  |.   
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEM--KYYIVHLKRHFMFR----NHLCLVFELLSYNLYDLLRNT

KKKGVPKALVKIIAKQVLLGLQYLHD-ECDLVHTDIKPENI
. .||   |.. .|.|..  | ..   | |..| |.|||||
HFRGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENI
Kinase CC1G_10260.AA PRP4 57-196 30 7.2e-15 50.92 In-house 1-137 (320) Show / Hide 
Range on Protein: 57-196
Range on HMM: 1-137/320
Sequence Identity: 30% (43 aa)

YRVVRKLGWGHFSTVWLVKDSQSGV-HSALKVVKSAGRYAETARDEIKLLSRVASVSPDHPGRAHIVSFLDSFSHQGPESSHICIVFEPLGENLLALIER
|||. . | | ||.|   .|   |    | |.. .      |   |.  | .      |   . |.|   ..|.|.     |.|.|||..  ||  .. .
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHR----QHMCLVFECMSMNLREVLKK

N-KKKGVPKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENI
  |..|     |   |.| .| |. |   |. .| |||| ||
YGKDVGLHLKAVRSYAQQLFLALKHLK-KCNILHADIKPDNI
Kinase CC1G_10260.AA Pkinase 535-607 25 3.3e-13 47.79 Pfam 150-230 (293) Show / Hide 
Range on Protein: 535-607
Range on HMM: 150-230/293
Sequence Identity: 25% (21 aa)

SIKIADLGNA----TPSKKHFTEDIQTRQYRAPEAIVGRKDWDTRADVWSVACVVFELLTAEYLFDPQ------GQGELFTKD
..||.| | |    . ..  .|    |. |.||| | |........|.||. |...|.|. . .|. .       | ... ..
CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRI
Kinase CC1G_10260.AA Ciliate-E2 536-698 13 8.7e-13 40.2 In-house 195-365 (365) Show / Hide 
Range on Protein: 536-698
Range on HMM: 195-365/365
Sequence Identity: 13% (30 aa)

IKIADLGNAT------------PSKKHFTEDIQ-----------------------TRQYRAPEAIVG--------RKDWDTRADVWSVACVVFELLTAE
|||.|.|...            .  | ...  .                       |  | ||| . |        .|..|. .|.||. .. .|.|. .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

YLFDPQGQGELFTKDDDHMAQIIELLGDFPLDVKMGGKYSRELFDHTGALRYIRTLKPWPLKRVMIEKYLYS------------------EEDSDALCAF
. |                                                         ..  .  |. ..                  .. |.    .
PPF---------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDL

LEP----MLKADMRERAH-ARDMLDHPWL
.      ||. |  .|   . . |.|||.
IKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CC1G_10260.AA DYRK 530-595 35 4e-12 41.85 In-house 139-204 (320) Show / Hide 
Range on Protein: 530-595
Range on HMM: 139-204/320
Sequence Identity: 35% (24 aa)

NP-PPISIKIADLGNATPSKKHFTEDIQTRQYRAPEAIVGRKDWDTRADVWSVACVVFELLTAEYLF
.|  .  ||..| | ..  .....  || | ||||| |.| .  ..  |.||. |.. ||.| . ||
QPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCP-YCYAIDMWSLGCILAELFTGWPLF
Kinase CC1G_10260.AA DYRK1 530-619 36 8.6e-11 33.63 In-house 139-220 (321) Show / Hide 
Range on Protein: 530-619
Range on HMM: 139-220/321
Sequence Identity: 36% (33 aa)

NPPPISIKIADLGNATPSKKHFTEDIQTRQYRAPEAIVGRKDWDTRADVWSVACVVFELLTAEYLFDPQGQGELFTKDDDHMAQIIELLG
||    ||| | | .  . .   . || | ||.|| ..| . .|.  |.||. |.. |. | | ||   |. |.     | | .|.| ||
NPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIE-YDMAIDMWSLGCILVEMHTGEPLF--SGSNEV-----DQMNKIVEVLG
Kinase CC1G_10260.AA DYRK2 535-590 38 5.1e-10 28.44 In-house 142-197 (318) Show / Hide 
Range on Protein: 535-590
Range on HMM: 142-197/318
Sequence Identity: 38% (22 aa)

SIKIADLGNATPSKK-HFTEDIQTRQYRAPEAIVGRKDWDTRADVWSVACVVFELLT
.||..| |  .  .  ..  .||.| |||||.|.| |  ..  | ||  |.. ||.|
GIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGK-YGMAIDMWSFGCIMAELYT
Kinase CC1G_10260.AA PRP4 556-596 43 2.4e-08 26.72 In-house 167-206 (320) Show / Hide 
Range on Protein: 556-596
Range on HMM: 167-206/320
Sequence Identity: 43% (18 aa)

QTRQYRAPEAIVGRKDWDTRADVWSVACVVFELLTAEYLFD
. | ||||| |.| .  |   |.|||.|  .|| |   .|.
VSRFYRAPEIIIGHP-YDYQIDMWSVGCTLYELYTGKIMFP
Kinase CC1G_10260.AA Ciliate-E2 146-196 32 1.2e-07 22.34 In-house 118-192 (365) Show / Hide 
Range on Protein: 146-196
Range on HMM: 118-192/365
Sequence Identity: 32% (24 aa)

GENLLALIERNKKKGVPK---------ALVKIIAKQVLL---------------GLQYLHDECDLVHTDIKPENI
| .|. .|. ||||   .           .| | ||.|                .|.||| .   .| |||||||
GGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENI
Kinase CC1G_10260.AA HIPK 533-588 38 8e-06 13.71 In-house 141-196 (329) Show / Hide 
Range on Protein: 533-588
Range on HMM: 141-196/329
Sequence Identity: 38% (22 aa)

PISIKIADLGNATPSKKHFTED-IQTRQYRAPEAIVGRKDWDTRADVWSVACVVFEL
|  .|. | | |    |  ..  .| | ||||| |.| .      |.||  ||. ||
PYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLP-FCENHDMWSLGCVIAEL
Kinase CC1G_10260.AA TyrKc 57-488 8 9.8e-05 -146.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 57-488
Range on HMM: 1-280/280
Sequence Identity: 8% (42 aa)

YRVVRKLGWGHFSTVWLVKDSQSGVHSALKVVKSAGRYAETARDEIKLLSRV-ASVSPDHPGRAHIVSFLDSFSHQG---PESSHICIVFE--PLGENLL
 .  .||| |.| .|.. . .   .  | |..|.     |  ..|.......      .||   .|| ..   ..||    ..  ..||.|  |.  .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGG----HHP---NIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLK

ALIERNKKKGVPKALVKIIAKQVLLGLQYLHDECDLVHTDIKPENICFTKSTCLEVT----SVRQTLE-------ELDE-----LTRSGIPIQ-------
  . ....| .. .    .. |.  | .|||.   ..| |.   |.  ..  .  ..    |   . .       .         ... .||        
DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

----------------------MKGKEKEPE-------------GLSAGSSPLKPSS----WIEQASSLSSSYKSKGSPFKSSKPRSSNRHGHSHSQSGA
                        |..  |.              . .|  . .| .                                           
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------------

PWQDPGVASPAPAVLVNAVASADGQETSQTAFNSLRTSSSSTSTITIAHSESSSTTATATQPSPTGTPLGPRKTKTMSIINGVSKLISDTSTMLSTGLHP
                                                                                                    
----------------------------------------------------------------------------------------------------

TSETKPNTNTTNRTPQSGETNVTTNHVSLLTQTAPTRISANVEPLRTTTTRPSPPQHISQLSAHMHSEPCPSLPSHDSVLSSHFPS-ETSRPNFTTVSTA
                                                                  . .| .   .. . ..       .||.|...   
------------------------------------------------------------------F-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHEC

I
.
F
Kinase CC1G_10260.AA Ciliate-E2 57-87 29 0.000264 10.66 In-house 1-31 (365) Show / Hide 
Range on Protein: 57-87
Range on HMM: 1-31/365
Sequence Identity: 29% (9 aa)

YRVVRKLGWGHFSTVWLVKDSQSGVHSALKV
| ...|.| | |..|...|. . .  .|.|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKI
Kinase CC1G_10260.AA Pkinase 653-698 16 0.002098 13.12 Pfam 227-293 (293) Show / Hide 
Range on Protein: 653-698
Range on HMM: 227-293/293
Sequence Identity: 16% (11 aa)

LKRVMIEKYLYSEEDS---------------------DALCAFLEPMLKADMRERAHARDMLDHPWL
..|.|  .. .... .                     .... |.. .|. |. .|  |.. | |||.
ICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CC1G_10260.AA DYRK 674-698 32 0.011578 6.11 In-house 296-320 (320) Show / Hide 
Range on Protein: 674-698
Range on HMM: 296-320/320
Sequence Identity: 32% (8 aa)

FLEPMLKADMRERAHARDMLDHPWL
|.. .|. | ..|  . . |.|||.
FIKKCLQWDPHKRITPSQALQHPWF
Kinase CC1G_10260.AA DYRK2 674-698 32 0.026835 2.9 In-house 294-318 (318) Show / Hide 
Range on Protein: 674-698
Range on HMM: 294-318/318
Sequence Identity: 32% (8 aa)

FLEPMLKADMRERAHARDMLDHPWL
|.   .. |  ||  ... |.|||.
FIKRCFEWDPSERMTPSQALKHPWI
Kinase CC1G_10260.AA WEE 57-71 40 0.079118 2.0 In-house 1-15 (297) Show / Hide 
Range on Protein: 57-71
Range on HMM: 1-15/297
Sequence Identity: 40% (6 aa)

YRVVRKLGWGHFSTV
. .| |.| | |..|
FQEVQKIGEGSFGEV