AqueK017

Species: A.queenslandica
Alias: AqueK017
External Links:
Annotation:

Classification

Group: AGC
Family: PKC
Subfamily: PKCd

Sequence

Name Sequence Type Origin Length Description Download
AqueK017.AA Protein None 721 None Fasta, JSON
AqueK017.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of AqueK017.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C2_PKD AqueK017.AA C2_PKD 2-124 28 2.4e-19 64.69 In-house 1-136 (183) Show / Hide
Range on Protein: 2-124
Range on HMM: 1-136/183
Sequence Identity: 28% (40 aa)

SAFLRLKLLKAEVAPA-------------PGVARV-DTFAAVSIKETEQSPQGPVLVQKKKTFYPEWGKCFDSHLVTGRRMMVEVMDRA--SPETKIAEM
. |.|..|. |..                |.  .. | . .| ..|.  . ..  ..||||||||||.||||.|.  ||    ..| .|   |.. .|| 
MGFCRVRLCRADGLKPKMFQHWHNLTFGKPADCEAIDPYCVVHVDEKHENQHIGQTTQKKKTFYPEWNKCFDHHVYEGRHIQIVCMHNAIMPPNKMVAEC

VVETEELSSICKEEPDPSSAINLALDLRPKGKLILQVKL
 .  |.. . ||     |.   . ..| | ||.  |.|.
TMKLEDCIEMCKT---NSGITHIWINLEPQGKVHVQIKW

C1_1 AqueK017.AA C1_1 170-222 34 2.7e-16 63.5 Pfam 1-55 (55) Show / Hide
Range on Protein: 170-222
Range on HMM: 1-55/55
Sequence Identity: 34% (19 aa)

HRFVKK-FFRQPVYCSYCHEFLWG-FTKPGFQCQVCAYTSHVKCVESIIANCTGA
|..| . .|.||..|..| ||.|| . ..|..||.| |. | .|..   ..| . 
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN

C1 AqueK017.AA C1 170-219 27 2.9e-15 57.93 SMART 1-61 (61) Show / Hide
Range on Protein: 170-219
Range on HMM: 1-61/61
Sequence Identity: 27% (17 aa)

HRFVKKFFRQPVYCSYCHEFLWGFTKP-----GFQCQVCAYTSHVKCVESIIA-------NC
|..... | .| ||..|....||. |.     |..|..| |. | ||.. . .       .|
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC

C1_1 AqueK017.AA C1_1 242-294 47 1.3e-20 79.27 Pfam 1-55 (55) Show / Hide
Range on Protein: 242-294
Range on HMM: 1-55/55
Sequence Identity: 47% (26 aa)

HRFKPH-SFLRPTFCDHCGQLMRG-LFRQGVKCGVCGVNCHSRCQPNIPNLCGVN
|....| .| .||||.|||....| |..||.|| .|..||| ||... |..|| |
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN

C1 AqueK017.AA C1 242-291 29 1.5e-18 68.89 SMART 1-61 (61) Show / Hide
Range on Protein: 242-291
Range on HMM: 1-61/61
Sequence Identity: 29% (18 aa)

HRFKPHSFLRPTFCDHCGQLMRGLFRQ-----GVKCGVCGVNCHSRCQPNIPN-------LC
|... ..| .||.|.||.....|.|.|     |..| .|...|| .|....|.        |
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC

Kinase AqueK017.AA PKC 394-652 61 2.6e-183 599.22 In-house 1-262 (262) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-262/262
Sequence Identity: 61% (162 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYFAIKALKKDVVLEDNDVESTFVEKRILALGSSHPFLTHLLCSFQTPSHLFFVMEYLNGGDLMFHIQVSHKFKL
|...|||||||||||.||.. ||.. |.|||.|||||...| |||.| .|||.|||.. ||||||| |.|||...|||||||.|||||||||| ...||.
FNFLKVLGKGSFGKVMLAER-KGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKE

PRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCKEGVFAPNKTGTFCGTPDYISPEIVKNERYSYSVDFWSLGVLSYEMLTGQSP
..||||||||||||||||.||||||||||||||||..|| |.||||||||...  ..| |||||||||.|||.. . |. |||.|..||| |||. ||||
EHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSP

FSGDSEEELFDSICNCNVPFPSFLAPSSIDYLKKLLERDPEKRLGCMEDR----MPIRSHPFF
|.|. |.|||.||.. |. .|  |.  . . .|......|||||||...     . ||.||||
FHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF

Kinase AqueK017.AA AGC 394-652 33 2.5e-177 463.2 In-house 1-395 (395) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-395/395
Sequence Identity: 33% (134 aa)

FQLIKVLGKGSFGKVLLAKLSK-----GNESYFAIKALKKDV-VLEDN--DVESTFVE------------KRILALGSS---------HPFLTH-LLCSF
|...||.|||||||| |..  .     ... |.|.| |||.. .....  .|| | .|            ..||.. ..         |||... | .||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTPSH--LFFVMEYLN---------GG-DLMFHIQ---VSHKFKLPRARFYAAE-------IICALQFLHS-KGIIYRD-LKLDNVLLDCDGHAKLADFG
|...|  |.|||||..         || .|..|.|    . .|  .||||||||       |..||..||| .|||.|| ||..|.||| ||| ||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

MCKEGVFAP--------------------------------------------------NKTGTFCG--TPDYISPEIVKNERYSYSVDFWS--LGVLSY
.||||.  .                                                  ..| ||||  ||.|..|||.    |....| ||  ||.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLTGQSPFSGDS----------EEELFDSIC------NCNVPFP----------SFLAPSSIDYLKKLLERDPEKRLGCMED------RMPIRSHPFF
|||||..||.||.          ..|.|..|.      |..|.||          ... |   | .||||..||||||||...         |..||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase AqueK017.AA Delta 394-652 67 5.8e-154 517.78 In-house 1-259 (259) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-259/259
Sequence Identity: 67% (175 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYFAIKALKKDVVLEDNDVESTFVEKRILALGSSHPFLTHLLCSFQTPSHLFFVMEYLNGGDLMFHIQVSHKFKL
|.. |||||||||||.|| | || . |.|||.||||||||| |||.|.||.|.|||.. ||||.||.|.||| .|||||||||||||||.||| .|.|..
FHFHKVLGKGSFGKVMLAEL-KGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDE

PRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCKEGVFAPNKTGTFCGTPDYISPEIVKNERYSYSVDFWSLGVLSYEMLTGQSP
 ||||||.||||.|||||.|||||||||||||||||||| |.|||||||| ..  .|. |||||||||.|||.| ..|. |||.|| ||| |||| ||||
KRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSP

FSGDSEEELFDSICNCNVPFPSFLAPSSIDYLKKLLERDPEKRLGC-MEDRMPIRSHPFF
|.|. |.|||.|||| .  .| ..   . | ||||.|||||||||     . .|| |.||
FHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF

Kinase AqueK017.AA Eta 394-652 59 4.6e-141 474.93 In-house 1-261 (261) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-261/261
Sequence Identity: 59% (157 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYFAIKALKKDVVLEDNDVESTFVEKRILALGSSHPFLTHLLCSFQTPSHLFFVMEYLNGGDLMFHIQVSHKFKL
|. ||||||||||||.||.. || .  .||| |||||.. | ||| |  |||||.|   ||||| | |.|||.  ||||||| |||||||.|| . ||  
FNFIKVLGKGSFGKVMLAER-KGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDE

PRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCKEGVFAPNKTGTFCGTPDYISPEIVKNERYSYSVDFWSLGVLSYEMLTGQSP
|||||||||..|||.||| .|.|||||||||.||| .|| |||||||||||.   . | ||||||||| |||..   |  |||.| .||| |||..||.|
PRARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPP

FSGDSEEELFDSICNCNVPFPSFLAPSSIDYLKKLLERDPEKRLGCME---DRMPIRSHPFF
|  | |..||.|| . .| .| .|    .  ||  . . |.||||||.   .   ||.||||
FEADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF

Kinase AqueK017.AA Alpha 394-652 57 3.6e-136 458.69 In-house 1-259 (259) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-259/259
Sequence Identity: 57% (149 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYFAIKALKKDVVLEDNDVESTFVEKRILALGSSHPFLTHLLCSFQTPSHLFFVMEYLNGGDLMFHIQVSHKFKL
|  ..||||||||||.||   || .  .||| |||||.  | ||| | ||||.|||..  |||. .   |||.  |.||||| ||||||.|||   ||| 
FNFLMVLGKGSFGKVMLAE-RKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKE

PRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCKEGVFAPNKTGTFCGTPDYISPEIVKNERYSYSVDFWSLGVLSYEMLTGQSP
| | ||||||  .| |||.|||||||||||||.|| .|| |.||||||||...  . | ||||||||| |||.  . |. ||| |. ||| |||. || |
PHAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPP

FSGDSEEELFDSICNCNVPFPSFLAPSSIDYLKKLLERDPEKRLGC-MEDRMPIRSHPFF
| |. |.||| .| . || .|  .   ..|  | .| . | |||||  ...  || ||||
FDGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF

Kinase AqueK017.AA Akt 394-652 47 1.7e-128 412.93 In-house 1-264 (264) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-264/264
Sequence Identity: 47% (126 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYFAIKALKKDVVLEDNDVESTFVEKRILALGSSHPFLTHLLCSFQTPSHLFFVMEYLNGGDLMFHIQVSHKFKL
|...|||||||||||.|.|  . .. |.|.|.||||. .. | || |. |..||     |||.. |  ||||. .|.|||.| |||.| .|.|   .|. 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

PRARFYAAEIICALQFLHSKGIIYRD-LKLDNVLLDCDGHAKLADFGMCKEGVFAP-NKTGTFCGTPDYISPEIVKNERYSYSVDFWS-LGVLSYEMLTG
.|||||.||||.|...||||.||||| ||. |.|.| ||| .|.|||.|||..     || |||||| |..||| ..  .. .||.|. ||.. |||..|
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

QSPFSGDSEEELFDSICNCNVPFP--SFLAPSSIDYLKKLLERDPEKRLG-CMEDRMPIRSHPFF
. ||  .  ...|. | |..| ||  ... |   | ...||..||.||||   .|   |..||.|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase AqueK017.AA SGK 394-652 40 1.9e-114 354.98 In-house 1-283 (283) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-283/283
Sequence Identity: 40% (114 aa)

FQLIKVLGKGSFGKVLLAKLSKG-----------------NESYFAIKALKKDVVL-------EDNDVESTFVEK-RILALGSSHPFLTHLLCSFQTPSH
|...||.||||||||...|  .                  ..  .|.| |.|. ..         . .  .  |.  || .  .|||.  |  .|||.  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKN-MKHPFIVNLHYAFQTKWK

LFFVMEYLNGGDLMFHIQVSHKFKLPRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCKEGVFAPNKTGTFCGTPDYISPEIVKN
|.|||.|.|||.. .|.|   .|. .|||||||||.|||  |||. ||||||| .|.|||..||..| ||| ||||. . ..| |||||| |  ||. . 
LYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRK

ERYSYSVDFWSLGVLSYEMLTGQSPFSGDSEEELFDSICNCNVPFPSFLAPSSIDYLKKLLERDPEKRLGCMEDRMPIRSHPFF
. .. .|| |.|| . |||..|  ||     ....| | |    .| .  ..  | .. ||..||.||||  .| | |..||||
QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF

Kinase AqueK017.AA PKN 394-652 51 9.1e-113 380.94 In-house 1-260 (260) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-260/260
Sequence Identity: 51% (135 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYFAIKALKKDVVLEDNDVESTFVEKRILALGSS--HPFLTHLLCSFQTPSHLFFVMEYLNGGDLMFHIQVSHKF
|..| |||.| ||||||... |... |.|||||||  ..  ..||| ..||||..  ..  ||||  |.  ||| .| .|||||. ||||| ||  .  |
FRCIAVLGRGHFGKVLLSQY-KHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIH-EDVF

KLPRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCKEGVFAPNKTGTFCGTPDYISPEIVKNERYSYSVDFWSLGVLSYEMLTGQ
. |||.|||| ..  ||.|| . ||||||||||.||| .|. |.||||.||||.    .|.||||||... ||.. .. |   ||.| |||| |||| | 
SEPRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGE

SPFSGDSEEELFDSICNCNVPFPSFLAPSSIDYLKKLLERDPEKRLGCME-DRMPIRSHPFF
.||.|| |||.||.| | .|..| ||.  .|. ...|| . ||.|||  | |   |. .|||
CPFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF

Kinase AqueK017.AA Iota 394-652 49 4.90000000001e-105 350.86 In-house 1-271 (271) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-271/271
Sequence Identity: 49% (134 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYFAIKALKKDVVLEDNDVESTFVEKRILALGSSHPFLTHLLCSFQTPSHLFFVMEYLNGGDLMFHIQVSHKFKL
|.||.|.|.||. |||.... | .  | |.| .||..| .| |..    || .    |.||||  |   |||.| ||||.|. ||||||||.|   |   
FELIRVIGRGSYAKVLMVEHKKTRRIY-AMKVIKKEMVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLPE

PRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCKEGVFAPNKTGTFCGTPDYISPEIVKNERYSYSVDFWSLGVLSYEMLTGQSP
  ||||.|||. ||.|||..||||||||||||||| .|| || |.||||||.     | |||||| || |||.. | | .|||.| |||| .||. | ||
EHARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSP

FS--G-------DSEEELFDSICNCNVPFPSFLAPSSIDYLKKLLERDPEKRLGCMEDR----MPIRSHPFF
|   |         |. ||  |   ..  | .|.      ||  | .||. ||||  .     | |..||||
FDIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF

Kinase AqueK017.AA RSK 397-652 39 2.2e-100 339.81 In-house 1-278 (278) Show / Hide
Range on Protein: 397-652
Range on HMM: 1-278/278
Sequence Identity: 39% (110 aa)

IKVLGKGSFGKVLLAKLS--KGNESYFAIKALKKDVVLEDN-DVESTFVEKRILALGSSHPFLTHLLCSFQTPSHLFFVMEYLNGGDLMFHIQ-VSHK--
.||||.|..||| | .    . .. ..| | ||| ..   . |.. |. | .||..  .|||. .|  .|||...|. .|||..||.|  |.|   |.  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FKLPRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDC---DGHAKLADFGMCKEGVFA-PNKTGTFCGTPDYISPEIVK---NER-YSYSVDFWSLGV
|   .|.||.|||..|...||..|||.||||..|.|.|    .|| || ||| ||...    ..| |||.| .|. ||..|    .. .. ..| |||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LSYEMLTGQSPFSG---DSEEELFDSICNCN--VPFP--SFLAPSSIDYLKKLLERDPEKRLGC-MEDRMPIRSHPFF
| ||||||..|| |   .. .|... |....  ...|  ..| .   | ..|.|.|||.|||||  .|   |..||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase AqueK017.AA S_TKc 394-652 35 1.8e-95 324.43 SMART 1-231 (231) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYFAIKALKKDVVLEDNDVESTFVEKRILALGSSHPFLTHLLCSFQTPSHLFFVMEYLNG--GDLMFHIQVSHK-
.......|||.|||| ...  |    ..||| .|          |..  | .||     ||.. .|. .||. .||..||||..|  |||. .|.   . 
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----FKLPRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCKEGVFAPNKTGTFCGTPDYISPEIVKNERYSY-SVDFWSLGVLS
     |   .||||...|.|||...||.|||.|||| .|.|||   | |..|||....         ||||||.|..||..    |.. ..| ||.|.. 
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YEMLTGQSPFSGDSEEELFDSICNCNVPFPSFLAPSSIDYLKKLLERDPEKRLGCMEDRM---PIRSHPFF
||||.|. ||.   ....|. |.           |. .| ..|.|..|||||... |       |..||.|
YEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK017.AA Pkinase 394-652 28 3e-82 284.33 Pfam 1-293 (293) Show / Hide
Range on Protein: 394-652
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYFAIKALKKDVVLEDNDVESTF-VEKRILALGSSHPFLTHLLCSFQTPSHLFFVMEYLNGG----DLMFHIQ--
.......|.||||.| ...  . ..  .|.| .||.   .. |.. .   | .|..   .||.   |...|....|. .||||..||    ||. .|.  
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

VSHKF--KLPRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHA----KLADFGMCKE--GVFAPNKTGTFCGTPDYISPEIVK-NERYSYSVDF
 . .|      ..||. .|...|...||.|||.||||..|.|.| .||     |..||| .|       .  . ||||||.|..||... .. |...|| 
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGVLSYEMLTGQSPFSGD------SEEELFDSICNCNVPFPSFLA---------------------PSSIDYLKKLLERDPEKRLGCMEDRMPIRSHP
||.|.. ||||.|. ||.|.      .. .... |  . ..|...                       .. .| .|..|..||.||.....    |  ||
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ----ILQHP

FF
.|
WF

Kinase AqueK017.AA S_TK_X 653-716 45 2.2e-26 94.91 SMART 1-79 (79) Show / Hide
Range on Protein: 653-716
Range on HMM: 1-79/79
Sequence Identity: 45% (36 aa)

SPIDWVKLET--RESEPPFKPKVK----SPGDVSNFDDDFTFQEPNLTPCDNRLVQSIDQSN---------FRGFSYTN
. ||| ||.   .| |||||||.|    ||.|.||||..|| ..| |||.|  |..|..|.          ||||.| .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase AqueK017.AA Pkinase_C 672-718 53 3.4e-17 63.74 Pfam 1-46 (46) Show / Hide
Range on Protein: 672-718
Range on HMM: 1-46/46
Sequence Identity: 53% (25 aa)

KVKSPGDVSNFDDDFTFQEPNLTPCDNRLVQSIDQSNFRGFSYTNDR
.|||| |.||||..|| . |..|| |.|   |.||..||||.|.|. 
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD

Kinase AqueK017.AA TyrKc 394-640 22 1.1e-14 14.85 SMART 1-280 (280) Show / Hide
Range on Protein: 394-640
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FQLIKVLGKGSFGKVLLAKLSKGNESYF-AIKALKKDVVLEDNDVESTFVEKRILALG-SSHPFLTHLLCSFQTP-------SHLFFVMEYLNGGDLMFH
 .|.|.|| | ||.| .....     .  |.| ||.|       .|    | ||.     .|| .  |.    ..         |. ||||  .|||  .
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IQVSHK-FKLPRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCKEGVFA-------PNKTGTFCGTPD------YISPEIVKNER
.. ... ....    ..  | |  ..||||..| |||   |.|.. ....| .|||.....            .. .  .  .        .||  .  .
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YSYSVDFWSLGVLSYEMLT-GQSPFSG-----DSEEELFDSICNCNVPFPSFL--------APSSI-DYLKKLLERDPEKR------LGCM
..   | || ||. .|..| ||.| .|      | .|..  . . . . .           .|. . .  |.  ..|||.|        |.
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK017.AA Pkinase_Tyr 468-542 26 1.1e-07 26.6 Pfam 81-159 (270) Show / Hide
Range on Protein: 468-542
Range on HMM: 81-159/270
Sequence Identity: 26% (21 aa)

HLFFVMEYLNGGDLMFHIQV----SHKFKLPRARFYAAEIICALQFLHSKGIIYRDLKLDNVLLDCDGHAKLADFGMCK
... ||||  .|||  . .      .......   ....| .....|.||..| |||   |.|.......| .|||...
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

Kinase AqueK017.AA Pkinase_Tyr 394-429 28 0.000377 14.68 Pfam 1-39 (270) Show / Hide
Range on Protein: 394-429
Range on HMM: 1-39/270
Sequence Identity: 28% (11 aa)

FQLIKVLGKGSFGKVLLAKLS---KGNESYFAIKALKKD
 ...|.||.|.||.| ....    ....   |.| || .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG

Kinase AqueK017.AA Pkinase_Tyr 562-596 35 0.033709 8.07 Pfam 182-218 (270) Show / Hide
Range on Protein: 562-596
Range on HMM: 182-218/270
Sequence Identity: 35% (13 aa)

SPEIVKNERYSYSVDFWSLGVLSYEMLT-GQSP-FSG
.||  .. ...   | || ||| .|..| |..| . |
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG