AqueK021

Species: A.queenslandica
Alias: AqueK021
External Links:
Annotation:

Classification

Group: AGC
Family: PKG

Sequence

Name Sequence Type Origin Length Description Download
AqueK021.AA Protein None 712 None Fasta, JSON
AqueK021.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of AqueK021.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
CNMP AqueK021.AA cNMP 128-241 27 1.2e-26 95.72 SMART 1-123 (123) Show / Hide
Range on Protein: 128-241
Range on HMM: 1-123/123
Sequence Identity: 27% (34 aa)

FLKNLEKVQTTEIVECMFPLDFKQDQFICREGAVGTELYVIAEGEVQVTKG---------GQVRTEMGPGKLFGELAILYNCTRTATIKAK-VDTKVWAL
..|||.. . .|....|.|  ..  . |.|.| .|...|.| .|.|.|.|          .|. ...||| .|||||.| . .|||...|. .. ..| .
MFKNLDEQELRELCDHMEPRHYPAGEYIFRQGDPGDHFYIIVSGWVRVYKTRVQHMEDGREQIVGFLGPGDFFGELALL-RRPRTAAARACCECCTIWRI

DRSCFQTIMMNHGIIRQSEYLSFL
|.  |. ....|. . . . ....
DFQHFMQQLQQHPQHMYRMLQQLA

CNMP_binding AqueK021.AA cNMP_binding 146-231 29 3.1e-24 85.87 Pfam 1-91 (91) Show / Hide
Range on Protein: 146-231
Range on HMM: 1-91/91
Sequence Identity: 29% (27 aa)

PLDFKQDQFICREGAVGTELYVIAEGEVQVTKGGQVRT-----EMGPGKLFGELAILYNC-TRTATIKAKVDTKVWALDRSCFQTIMMNHGI
.. .| ...|...|  .. .|.. .|.|.|.| ..        ..||| .|||.|...|. .||||..|  |...|...|. |. .|..|  
VRHYKKGEVIFHQGDPCDHFYIVLSGKVKVYK-DEDGREQILGFLGPGDFFGEMALFTNQNPRTATVVALTDCECWRIPREDFRQLMQQHPE

CNMP AqueK021.AA cNMP 246-365 33 2.2e-27 98.21 SMART 1-123 (123) Show / Hide
Range on Protein: 246-365
Range on HMM: 1-123/123
Sequence Identity: 33% (41 aa)

ELRMLNERDLMKLADVLQEDFYPQGEYIIRQRQTGETFFIISDGTVKITKQ---ASPDAPEETIRELGRGDYFGEKALLGDKYRTASVIAT-SNVCCLCV
 .. |.| .| .|.|.... .|| ||||.|| . |..|.||..|.|...|.     .|  | ....||.||.||| ||| .  |||...|  . .... .
MFKNLDEQELRELCDHMEPRHYPAGEYIFRQGDPGDHFYIIVSGWVRVYKTRVQHMEDGREQIVGFLGPGDFFGELALL-RRPRTAAARACCECCTIWRI

DRDHFTQLIGNLVERTYKDSEEKK
|..|| |....  .. |.. ..  
DFQHFMQQLQQHPQHMYRMLQQLA

CNMP_binding AqueK021.AA cNMP_binding 264-355 33 9.7e-24 84.15 Pfam 1-91 (91) Show / Hide
Range on Protein: 264-355
Range on HMM: 1-91/91
Sequence Identity: 33% (31 aa)

EDFYPQGEYIIRQRQTGETFFIISDGTVKITKQASPDAPEETIRELGRGDYFGEKALLGDK-YRTASVIATSNVCCLCVDRDHFTQLIGNLVE
.  |. ||.|..| . .. |.|. .|.||..|  .      ....||.||.||| ||....  |||.|.| . . |....|..| ||. .  |
VRHYKKGEVIFHQGDPCDHFYIVLSGKVKVYK-DEDGREQ-ILGFLGPGDFFGEMALFTNQNPRTATVVALTDCECWRIPREDFRQLMQQHPE

Kinase AqueK021.AA PKG 387-646 76 5.6e-215 720.47 In-house 1-260 (260) Show / Hide
Range on Protein: 387-646
Range on HMM: 1-260/260
Sequence Identity: 76% (198 aa)

LVRVETLGMGGFGRVELVQLKTDSTRTFALKCLRKKHIVDTRQQEHIFSEKSIMLSGRSPFITRLYKTFRCPKYLYMLLEVCLGGELWTILRDRGSFDDA
| .. |||.||||||||||.. .. |||||||..|.|||||||||||.||| ||.. |..|| |||.|||  ||.|||.|.|.||||||||||||.||| 
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

TTRFCTACVVEAFQYLHSREIVYRDLKPENLLLDNAGYVKLVDFGFAKYIGPGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFS
||||..||||||| |||.. |.|||||||||.||| ||.||||||||| || |||||||||||||||||||||||||.|.|||.|||||.|||||.||||
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS

GADPMRTYNIILKGIDVVDFPKKITRSAQNLIKKLCRDNPAERLGYLRNGLNDIKGHRWF
| |||.||||||||||...||.||||.|||.|||||||||.|||||..||.|||| |.||
GSDPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF

Kinase AqueK021.AA AGC 387-646 29 1e-158 413.94 In-house 1-395 (395) Show / Hide
Range on Protein: 387-646
Range on HMM: 1-395/395
Sequence Identity: 29% (118 aa)

LVRVETLGMGGFGRVELVQLKT-----DSTRTFALKCLRKKH-IVDTR--QQEHIFSE------------KSIMLSGR----------SPFITR-LYKTF
   . ..| |.||.| ||. |.     |. . .|.|.|.||| ||...  ..||. .|            . |.   .          .|||.. |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

RCPKY--LYMLLEVCL---------GG-ELWTILR---DRGSFDDATTRFCTAC-------VVEAFQYLHS-REIVYRD-LKPENLLLDNAGYVKLVDFG
  ...  ||...| .          || ||...|.   ..|.||  ..|| .|.       .| |..|||| . |..|| |||||.|||. |..||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKYIGPGR---------------------------------------------------KTWTFCG--TPEYVAPEIILNKGHDLSADYWS--LGILMY
..| .  ..                                                   .||||||  ||||.||||.    .. ..|.||  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLTGSPPFSGA----------DPMRTYNIILKGI----DVVDFP----------KKITRSAQNLIKKLCRDNPAERLGYLRN-----GLNDIKGHRWF
|.||| |||.|           .|| ... |..|.    . | ||          ....  |..|||||.  .|..|||...|     | ..|| | ||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase AqueK021.AA PKA 387-646 45 2e-118 399.76 In-house 1-263 (263) Show / Hide
Range on Protein: 387-646
Range on HMM: 1-263/263
Sequence Identity: 45% (123 aa)

LVRVETLGMGGFGRVELVQLKTDSTRTFALKCLRKKHIVDTRQQEHIFSEKSIMLSGRSPFITR-LYKTFRCPKYLYMLLEVCLGGELWTILRDRGSFDD
  .. |||.| ||||.|.. |..  . .|.|.|.|  ||...|.||. .||.|... ..||| . .| || ...||||..| . |||. . || .|.|. 
FEIIQTLGTGSFGRVMLCRHKHSG-NYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

ATTRFCTA-CVVEAFQYLHSREIVYRDLKPENLLLDNAGYVKLVDFGFAKYIGPGRKTWTFCGTPEYVAPEIILNK-GHDLSADYWSLGILMYELLTGSP
 ...|  |  .| |..|||| .|.||||||||.|.|. |..|. ||||||..     ||| |||||| |||||..| ||  | | |.|||| ||.|.| |
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFSGA--DPMRTYNIILKGIDVVDFPKKITRSA---QNLIKKLCRDNPAERLGYLRNGLNDIKGHRWF
||.    ||| .|. |..|   ..||  ..  |     |||||   .. .|.| ..|| |||| |.||
PFYDHNRDPMQIYEKICNGK--IKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase AqueK021.AA AktR 388-646 40 3.8e-94 319.08 In-house 2-268 (268) Show / Hide
Range on Protein: 388-646
Range on HMM: 2-268/268
Sequence Identity: 40% (107 aa)

VRVETLGMGGFGRVELVQLKTDSTRTFALKCLRKKHIVDTRQQEHIFSEKSIML-SGRSPFITRLYKTFRCPKYLYMLLEVCLGGELWTILRDRGSFDDA
.. . ||.|.||.| ||| | |. . .|.| ..||.|.. .|..|.  |. ||    . ||| .|...|   ..|. ..| | |||| ..|. .. |.  
HVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSEE

TTRFCTACVVEAFQYLHSR-EIVYRDLKPENLLLDNAGYVKLVDFGFAK---YIGPGRKTWTFCGTPEYVAPEIILN-KGHDLSADYWSLGILMYELLTG
..||  | .. |..|||..  |.||||||||.|||  |.||..||| .|    .    |. .|||||||.|||.|.. |||. |.|.|..||. ||..||
QARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTG

SPPFSGADPMRTYNIILKGI-DVVDFPKKITRSAQNLIK-KLCRDNPAERLGYLRNGLNDIKGHRWF
 |||   .  . .  |..     ...|....  ...||. ||  .|| .|||| .||  .|| | ||
CPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase AqueK021.AA RSK 390-646 37 3.1e-89 302.78 In-house 1-278 (278) Show / Hide
Range on Protein: 390-646
Range on HMM: 1-278/278
Sequence Identity: 37% (104 aa)

VETLGMGGFGRVELVQLKT--DSTRTFALKCLRKKHIVDTRQ-QEHIFSEKSIMLSGR-SPFITRLYKTFRCPKYLYMLLEVCLGGELWTILRDRGS---
.. || ||.| | |.. .|  |. . .| | |.|. || .   ..| . | .|..  . .||| .|. .|. ...||. .| | |||| | |. ...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDDATTRFCTACVVEAFQYLHSREIVYRDLKPENLLLDN---AGYVKLVDFGFAKY--IGPGRKTWTFCGTPEYVAPEIIL----NKGHDLSADYWSLGI
|.  . .|  | .| | ..||.. |..||||||| |.|.    | .||.||||.|.  .  . .| |||.| ||.|||..     ..||| ..|.||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMYELLTGSPPFSG---ADPMRTYNIILKGIDVVDFP--KKITRSAQNLIKKLCRDNPAERLGYLRNGLNDIKGHRWF
||||.||| ||| |   ...  . . |.||   ...|  ..... |..||.|.   .|. |||. ......|| | ||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase AqueK021.AA Akt 390-646 39 4e-89 285.04 In-house 4-264 (264) Show / Hide
Range on Protein: 390-646
Range on HMM: 4-264/264
Sequence Identity: 39% (105 aa)

VETLGMGGFGRVELVQLKTDSTRTF-ALKCLRKKHIVDTRQQEHIFSEKSIMLSGRSPFITRLYKTFRCPKYLYMLLEVCLGGELWTILRDRGSFDDATT
.. || | ||.| ||. | |. . . |.| |.|..|.. .| ||.. |. |    ..|||. |.  |  ...||. .. | |||| . |. .. |.  ..
LKVLGKGSFGKVFLVK-KKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRA

RFCTACVVEAFQYLHSREIVYRD-LKPENLLLDNAGYVKLVDFGFAK-Y-IGPGRKTWTFCGTPEYVAPEIILNKGHDLSADYWS-LGILMYELLTGSPP
||  | .. | ..|||. |.||| |||||.|.|. |...| ||| .|   |  . || |||||||| ||||....||. ..| |. ||..|||...| ||
RFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPP

FSGADPMRTYNIILKGIDVVDFP--KKITRSAQNLIKKLCRDNPAERLGYLRNGLNDIKGHRWF
|   |  . .  |. .   | ||  ..|   ...||..|.  .| .|||.  |....|| | ||
FYNQDHHQMFKKIKNQ--PVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase AqueK021.AA S_TKc 387-646 31 4.4e-88 299.85 SMART 1-231 (231) Show / Hide
Range on Protein: 387-646
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

LVRVETLGMGGFGRVELVQLKTDSTRTFALKCLRKKHIVDTRQQEHIFSEKSIMLSGRSPFITRLYKTFRCPKYLYMLLEVCLG--GELWTILRDRGS--
   ....| |.||.| ... |  . | .|.|...          ||| .| .|. . . |.| .|| .|.  ..||| .| | |  |.| .....||.  
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FDDATTRFCTACVVEAFQYLHSREIVYRDLKPENLLLDNAGYVKLVDFGFAKYIGPGRKTWTFCGTPEYVAPEIILNKGHDL-SADYWSLGILMYE
    |.  ..|| .. ...| .|.||. |..|||||||.|||.   .|. |||.|. .       ||||||.|.|||..   |..  ..| ||.|...||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLTGSPPFSGADPMRTYNIILKGIDVVDFPKKITRSAQNLIKKLCRDNPAERLGYLRNGL--NDIKGHRWF
.|.| |||.  ........|.            ...| ..|.|... .|..|..         ||| | ||
MLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK021.AA Pkinase 387-646 29 1.9e-86 298.31 Pfam 1-293 (293) Show / Hide
Range on Protein: 387-646
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

LVRVETLGMGGFGRVELVQLKTDSTRTFALKCLRKKHIVDTRQQEHIF-SEKSIMLSGRSPFITRLYKTFRCPKYLYMLLEVCLGG----ELWTILR--D
.......| |.||.| . . | ..  ..|.|...|.|. .  .|.|.  || .||.. ..|.| ||| .|. ....|| .| | ||    .|.....  .
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

RGSF--DDATTRFCTACVVEAFQYLHSREIVYRDLKPENLLLDNAGYV----KLVDFGFAKY--IGPGRKTWTFCGTPEYVAPEIIL-NKGHDLSADYWS
.|.|  .. . .|.   .... .|.||. |..|||||||.|.|| |..    |. |||.||   . ... ..||||||.|.|||.|. ..... ..| ||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGILMYELLTGSPPFSGA------DPMRTYNIILKGIDVVDFPKKIT-------------------RSAQNLIKKLCRDNPAERLGYLRNGLNDIKGHRW
.|...||.|.| |||.|.      |.|  .. |....   |.|....                   .... .||.... .|..|..       .|. | |
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPW

F
|
F

Kinase AqueK021.AA SGK 390-646 34 1.3e-83 257.96 In-house 4-283 (283) Show / Hide
Range on Protein: 390-646
Range on HMM: 4-283/283
Sequence Identity: 34% (98 aa)

VETLGMGGFGRVELVQLKTD-----------------STRTFALKCLRKKHIV-------DTRQQEHIFSEK-SIMLSGRSPFITRLYKTFRCPKYLYML
  ..| |.||.| .|. | |                     .|.| |.|.||.          .| || .|.  |.   ..|||  |   |  ...||. 
LKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKLYFV

LEVCLGGELWTILRDRGSFDDATTRFCTACVVEAFQYLHSREIVYRDLKPENLLLDNAGYVKLVDFGFAK-YIGPGRKTWTFCGTPEYVAPEIILNKGHD
..   |||.   |. ...|     || .| .| |  ||||  |.||||||||.|||  |...| ||| .|  | .  .| |||||||| |||... ..||
MDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPHD

LSADYWSLGILMYELLTGSPPFSGADPMRTYNIILKGIDVVDFPKKITRSAQNLIKKLCRDNPAERLGYLRNGLNDIKGHRWF
 . | |.||...||...| |||   .    |  |...     .|. .. .|  ||. |   .| .|||  ...  .|| | .|
RTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQ--PLQIPPQMSNDAWDLIQGLLQKDPKKRLG-TKRDFMEIKNHPFF

Kinase AqueK021.AA Ciliate-E2b 387-646 32 3.8e-82 249.39 In-house 1-272 (272) Show / Hide
Range on Protein: 387-646
Range on HMM: 1-272/272
Sequence Identity: 32% (89 aa)

LVRVETLGMGGFGRVELVQLKTDSTRTFALKCLRKKHIVDTRQQEHIFSEKSIMLSGRSPFITRLYKTFRCPKYLYMLLEVCLGGELWTILRDRG--SFD
.. .  || | || | ||.   .. . .|.||  |  |. .    |. .||....    ||| .....|.  ...|...| | |.|| ...|. |   . 
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

DATTRFCTACVVEAFQYLHSREIVYRDLKPENLLLDNAGYVKLVDFGFAKYIGPGRK----TWTFCGTPEYVAPEIIL-----NKGHDLSADYWSLGILM
    .| .| .. ...|||...|.|||.|||| ..|..||.||.|.| ||..         | | .|||.| |||||      .||   ..| ||.||  
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

YELLTGSPPFS--GADPMRTYNIILKGIDVVDFPKKITRSAQ--NLIKKLCRDNPAERLGYLRNGLNDIKGHRWF
||.. | .|.     ||   |  |.|. | ..||  ..      .|. ..   .|  |||      .  | | ||
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLG---GSYSWLKSHPWF

Kinase AqueK021.AA p70 386-646 36 1.1e-75 257.79 In-house 2-299 (299) Show / Hide
Range on Protein: 386-646
Range on HMM: 2-299/299
Sequence Identity: 36% (110 aa)

DLVRVETLGMGGFGRVELVQLKT--DSTRTFALKCLRKKHIV----DTRQQE----------------------HIFSEKSIMLSGRSPFITRLYKTFRC
 |..|  || ||.| | .|   |  |. . .| | |||  ||    ||.                           | | .|  .  .|||  |   |  
ELLKV--LGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQT

PKYLYMLLEVCLGGELWTILRDRGSFDDATTRFCTACVVEAFQYLHSREIVYRDLKPENLLLDNAGYVKLVDFGFAKY-IGPGRK----------TWTFC
   || .||   ||||.. |   | ..  |..|  . .. | ..||.. |.|||||||| .|. .| |.| |||  |. |  | .          |.|||
NGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFC

GTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFSGADPMRTYNIILKGIDVVDFPKKITRSAQNLIKKLCRDNPAERLGYLRNGLNDIKGHRWF
||.|| ||||.. .||.   |.||||.|||  |||.||| |  .  | . ||||   .  | . | ..  |||||   .|..|.|   .   ||. | .|
GTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF





Kinase AqueK021.AA Ciliate-E2 387-646 22 2.7e-73 249.8 In-house 1-365 (365) Show / Hide
Range on Protein: 387-646
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

LVRVETLGMGGFGRVELVQLKTDSTRT----------------------FALKCLRKKHIVDTRQQEHIF----------SEKSIMLSGRSPFITRLYKT
   .. .| |.|| | ... . .  .                       .|.|...|. |  . | .||.           ||.|. .  .|.| ..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FR--CPKYLYMLLEVCLGGELWTILRDR-----------GSFDDATTR---------------FCTACVVEAFQYLHSRE-IVYRDLKPENLLLDNAGYV
|     ...|. .| | ||.|. .....           ..|..   .               |  ||...|..||||.  |..||.||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLVDFGFAKYIGPG--------------------------------RKTWTFCGTPEYVAPEIILNKG---------HDLSADYWSLGILMYELLTGSPP
|..|||..|.. .                                   ..|.||||.|.||||. .|.         .| ..|.||||...||.|.| ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FSGADPMRTYNIILKGIDVVDFP----------------KKITRSAQNLIKK----LCRDNPAERLGYLRNGLNDIKGHRWF
|        ...|...    ..|                ||.. ....||||    .   .| .|..    | ..|. | ||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF

Kinase AqueK021.AA S_TK_X 647-698 26 1e-12 49.52 SMART 1-79 (79) Show / Hide
Range on Protein: 647-698
Range on HMM: 1-79/79
Sequence Identity: 26% (21 aa)

QGFDWEGLKK--RVVVPPIVPNVR----GATDTSNFD-HFPA-----SQEDI---------------PPDDLSGWDKDF
 |.||..| .  . . ||..|...    ..|||||||  |.      .  |                |||.  |....|
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase AqueK021.AA TyrKc 387-637 20 2.5e-11 -39.58 SMART 1-280 (280) Show / Hide
Range on Protein: 387-637
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

LVRVETLGMGGFGRVELVQLKTDSTRTFALKCLRKKHIVDTRQQEHIFSEKSIMLSG--RSPFITRLYKTFRCP-------KYLYMLLEVCLGGELWTIL
..  ..|| | ||.| . ..|    .. | |.|.. .      .| . .| .|| .   . | | |||   . .       . |....| . .| |   |
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

RDRGSFDDATTRFCTACVV-------EAFQYLHSREIVYRDLKPENLLLDNAGYVKLVDFGFAKYIGPG-----RKTWTFC----GTPE-----YVAPEI
|...        .|..  .       .  .||||. .. |||   | |... . ||  ||| ...|. .     .|         |.         ||| 
RKHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

ILNKGHDLSADYWSLGILMYELLT-GSPPFSG-----ADPMRTYNIILKGIDVVDFPKK--------ITRSAQNLIKKLCRDNPAERL--GYLRNGL
|  .      | || |..|.|..| | .| .|      .. . .. . .| .  . |.          .    ...|. .. .|..|     ..  .
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG-YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF