Gene AqueK022 (A.queenslandica)

AqueK022

Species: A.queenslandica
Alias: AqueK022
External Links:
Annotation:

Classification

Group: AGC
Family: PKN

Sequence

Name Sequence Type Origin Length Description Download
AqueK022.AA Protein None 1220 None Fasta, JSON
AqueK022.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of AqueK022.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HR1 AqueK022.AA HR1 156-223 30 1e-14 55.9 Pfam 1-74 (74) Show / Hide 
Range on Protein: 156-223
Range on HMM: 1-74/74
Sequence Identity: 30% (23 aa)

TLKESLRLEIRKEFKIKEGAENLLKV---TRDKKA----RAHVGSILKTCTERIDQLRSDLTALLAQVPDEEDAT
  ...|| .|..| ||||||||....   | |.|.    |... . |. .  .|..||. |  | ....| ....
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
HR1 AqueK022.AA HR1 241-314 32 2.4e-18 68.9 Pfam 1-74 (74) Show / Hide 
Range on Protein: 241-314
Range on HMM: 1-74/74
Sequence Identity: 32% (25 aa)

QAITDLDRQLEIEQKVKAGAENMIKMY--SNAKSSKDRKLLVEAQQMYSDSRTKIEVLRMRIMKTKSALSSSPEKG
|.. .| ...|.| |.| |||||...|  ....... ||.. ..||| ..|..||| |||.. | .. ..   . .
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKH-RKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
HR1 AqueK022.AA HR1 329-396 21 9.2e-07 27.38 Pfam 1-74 (74) Show / Hide 
Range on Protein: 329-396
Range on HMM: 1-74/74
Sequence Identity: 21% (16 aa)

GRVSYIRYRIDVESRLIEGARKIMR----ANPNSK---AYSTAGENEKLSAQKLKLLKLSLENRLTEFPHLAEDS
 | . .| .|..| ...|||....|    .. |.|   . . .  . . | ||. .|. .|| .  . .   ...
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
Kinase AqueK022.AA PKN 891-1150 81 1.7e-188 632.5 In-house 1-260 (260) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-260/260
Sequence Identity: 81% (213 aa)

YKFIAVLGRGHFGKVLLAEDKNTKELVAVKVLKKGDIISRDEVESLMSEKRIFEKINAVRHPFLVNLHCCFQSENNVCFVMEYACGGDLMMHIHQDIFKE
...||||||||||||||.. |.| |. |.|.|||.||..||||||||.||||||  |..||||||||. ||| |. |||||||| |||||||||.|.|.|
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHEDVFSE

PRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFVKVADFGLCKEGMWYGSRTSTFCGTPEFLAPEVLTDVSYTRAVDWWGLGVLIYEMLVGESP
|||||||||||||||||||. |.|||||||||||| .|.||.|||||||||| || ||||||||||||||||||| ||||||||||||||||||||||.|
PRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGECP

FPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRKLLRRNPERRLGAGERDAEDIKRQPFF
|||.|||||||.||||||||||||| |||.|||.|||.||||||||||||||||| ||||
FPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF
Kinase AqueK022.AA AGC 891-1150 33 5.5e-184 480.81 In-house 1-395 (395) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-395/395
Sequence Identity: 33% (135 aa)

YKFIAVLGRGHFGKVLLAEDK------NTKELVAVKVLKKGD-IISRD--EVESLMSE------------KRIFEKINAVR-------HPFLVN-LHCCF
..|. |.|.|.|||| |...|       |... |.||||| . |. ..  .||  |.|            ..|.||.|  .       |||.|. ||..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QSENN--VCFVMEYAC---------GG-DLMMHIHQD----IFKEPRACFYAAC-------VVLGLQYLHE-NGIVYRD-LKLDNLLLDVDGFVKVADFG
|....  ..|||||..         || .|..|.. .    .| |.||.||||.       .||.|.|||. .||..|| ||..|.||| || .| .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKEGMWYG--------------------------------------------------SRTSTFCG--TPEFLAPEVLTDVSYTRAVDWWG--LGVLIY
|||||| .|                                                   ||.||||  |||..|||.|    |..|.|||.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLVGESPFPGE----------DEEEVFDSIV------NDDVRYP----------RFLSSEAISIMRKLLRRNPERRLGAGERD-----AEDIKRQPFF
|||.| .|| |.          ...|.|..|       |..|..|          |..|.|| ....||| ..||.|||.|..|     ||.||. |.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase AqueK022.AA PKC 891-1150 55 3.5e-153 500.0 In-house 1-262 (262) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-262/262
Sequence Identity: 55% (148 aa)

YKFIAVLGRGHFGKVLLAEDKNTKELVAVKVLKKGDIISRDEVESLMSEKRIFEKINAVRHPFLVNLHCCFQSENNVCFVMEYACGGDLMMHIHQDI--F
 .|. |||.| ||||.||| |.|.|. |.|||||  ||  | ||. | |||...   | .||||..||||||....  |||||  ||||| || |..  |
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLAL--AWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHI-QQQRRF

KEPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFVKVADFGLCKEGMWYGSRTSTFCGTPEFLAPEVLTDVSYTRAVDWWGLGVLIYEMLVGE
||..| |||| ....||.|||.||.|||||||| ||| .| .| ||||.|||.||.|..||||||||...|||.|    |. .|||| .||| |||..| 
KEEHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQ

SPFPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRKLLRRNPERRLGAGERD---AEDIKRQPFF
||| ||||.|.|.|| .|...||| || || ||. ... .|||.|||.....   ..||.. |||
SPFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase AqueK022.AA Akt 891-1150 44 6.30000000001e-127 407.8 In-house 1-264 (264) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-264/264
Sequence Identity: 44% (120 aa)

YKFIAVLGRGHFGKVLLAEDKNTKELV-AVKVLKKGDIISRDEVESLMSEKRIFEKINAVRHPFLVNLHCCFQSENNVCFVMEYACGGDLMMHIHQD-IF
  |. |||.| ||||.|...|.|...  | |||||  || ...||  . |..| ...|   |||.||||  ||.... .|||.|. ||.|  |.... .|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN---HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRF

KEPRACFYAACVVLGLQYLHENGIVYRD-LKLDNLLLDVDGFVKVADFGLCKEG-MWYGSRTSTFCGTPEFLAPEVLTDVSYTRAVDWWG-LGVLIYEML
.|.|| ||.| ..|....||...|.||| ||. |.|.| || ....|||||||. . .. .| ||||||| ||||.| .. .|.|||||| ||...|||.
SEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMM

VGESPFPGEDEEEVFDSIVNDDVRYP--RFLSSEAISIMRKLLRRNPERRLGAGERDAEDIKRQPFF
 |  ||  .| .. |. | | .|..|  ...| |. .. ..|| ..|..|||.|. ||..||| |.|
CGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase AqueK022.AA Alpha 891-1150 52 2e-123 416.37 In-house 1-259 (259) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-259/259
Sequence Identity: 52% (137 aa)

YKFIAVLGRGHFGKVLLAEDKNTKELVAVKVLKKGDIISRDEVESLMSEKRIFEKINAVRHPFLVNLHCCFQSENNVCFVMEYACGGDLMMHIHQ-DIFK
. |. |||.| ||||.||| | |.|| |.|.|||  ||  | ||  | |||.    .  . |||| .| |||      |||||  ||||| || |   ||
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPG--KPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFK

EPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFVKVADFGLCKEGMWYGSRTSTFCGTPEFLAPEVLTDVSYTRAVDWWGLGVLIYEMLVGES
|| | |||| .  || .||| ||.|||||||| .|| .| .|.||||.|||.|| .. | ||||||...|||.     | ..||||  ||| |||..|  
EPHAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQP

PFPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRKLLRRNPERRLGAGERDAEDIKRQPFF
|| ||||.|.| .| .  | ||. .| ||..| . .| ..| .|||.|  . .||.  |||
PFDGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF
Kinase AqueK022.AA Eta 891-1150 52 3.3e-121 408.96 In-house 1-261 (261) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-261/261
Sequence Identity: 52% (138 aa)

YKFIAVLGRGHFGKVLLAEDKNTKELVAVKVLKKGDIISRDEVESLMSEKRIFEKINAVRHPFLVNLHCCFQSENNVCFVMEYACGGDLMMHIHQD-IFK
..|| |||.| ||||.||| |.| |. |.|||||  ||  |.||  | ||||     | .|||| .|||||| .  . |||||  ||||| .| .   | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRIL--SLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFD

EPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFVKVADFGLCKEGMWYGSRTSTFCGTPEFLAPEVLTDVSYTRAVDWWGLGVLIYEMLVGES
|||| |||| |.. |..||..|..||||||||.||| .|  |.||||.||||.  |  |.||||||...|||.| .. |  .|||| .|||.|||. |..
EPRARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQP

PFPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRKLLRRNPERRLGAGE--RDAEDIKRQPFF
||  . |...|.||..||| || .|. ||.||..  . .||..|||. .   . ..|.. |||
PFEADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase AqueK022.AA Delta 891-1150 51 1.3e-116 393.67 In-house 1-259 (259) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-259/259
Sequence Identity: 51% (135 aa)

YKFIAVLGRGHFGKVLLAEDKNTKELVAVKVLKKGDIISRDEVESLMSEKRIFEKINAVRHPFLVNLHCCFQSENNVCFVMEYACGGDLMMHIHQDI-FK
..| .|||.| ||||.||| |....  |.| |||  ..  |.||. | |.|.   . |..||||  | | ||..... |||||  ||||| || |   |.
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVL--ALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFD

EPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFVKVADFGLCKEGMWYGSRTSTFCGTPEFLAPEVLTDVSYTRAVDWWGLGVLIYEMLVGES
| || |||. ...|||.||..||.||||||||.||| || .|.||||.||| |   ...|||||||...|||..    |...||||  |||.||||.| |
EKRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQS

PFPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRKLLRRNPERRLGAGERDAEDIKRQPFF
|| ||||.|.|.||.||   |||... || ....||. |.||.|||  .  . ||.. .||
PFHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase AqueK022.AA SGK 891-1150 39 3.7e-111 344.6 In-house 1-283 (283) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-283/283
Sequence Identity: 39% (114 aa)

YKFIAVLGRGHFGKVLLAEDKNT------------------KELVAVKVLKKGDII-------SRDEVESLMSEK-RIFEKINAVRHPFLVNLHCCFQSE
 .|. |.| | ||||.... | .                  . . |.|||.|  ||        . |.   |.|.  |   .. ..|||.||||  || .
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVI---LKNMKHPFIVNLHYAFQTK

NNVCFVMEYACGGDLMMHIH-QDIFKEPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFVKVADFGLCKEGMWYGSRTSTFCGTPEFLAPEVL
    |||.|. ||..  |.    .|.|.|| |||| .|. | |||.  |.||||| .|.||| .| ..  ||||||||.     |.||||||| ||||||
WKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL

TDVSYTRAVDWWGLGVLIYEMLVGESPFPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRKLLRRNPERRLGAGERDAEDIKRQPFF
    . |.|||| || . |||..|  ||   . .. .| | | . . |.. |..| ...  || ..|. |||.  ||...||. |||
RKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF
Kinase AqueK022.AA S_TKc 891-1150 35 5.6e-103 349.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-231/231
Sequence Identity: 35% (97 aa)

YKFIAVLGRGHFGKVLLAEDKNTKELVAVKVLKKGDIISRDEVESLMSEKRIFEKINAVRHPFLVNLHCCFQSENNVCFVMEYACG--GDLMMHIHQDI-
|... ..|.| |||| .. .|.|...||.|..|          |....| .| .|    .||..|.|. .||. .....||||. |  |||. .|..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------FKEPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFVKVADFGLCKEGMWYGSRTSTFCGTPEFLAPEVLTDVSYTR-AVDWWGLGVL
      | | .|.||.. ....|.|.|..||..|||| .|.|||    .|..||||...        .||||||...|||||   .|.. ..||| .|..
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

IYEMLVGESPFPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRKLLRRNPERRLGAGERDA--EDIKRQPFF
.||||.|. |||  .....|. |.          |.||....||.|...||.|..| |  .  .|||  |.|
LYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK022.AA AktR 891-1150 40 2.8e-101 342.76 In-house 1-268 (268) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-268/268
Sequence Identity: 40% (110 aa)

YKFIAVLGRGHFGKVLLAEDK-NTKELVAVKVLKKGDIISRDEVESLMSEKRIFE-KINAVRHPFLVNLHCCFQSENNVCFVMEYACGGDLMMHIH-QDI
......||.| |||| |...| ......| |..|| .|| |   . .  |. | | ..|   |||.|.|| |||....  |.||| .||.|  |.  .  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCN---HPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKK

FKEPRACFYAACVVLGLQYLHEN-GIVYRDLKLDNLLLDVDGFVKVADFGLCK-EGMW-YGSRTSTFCGTPEFLAPEVLTD-VSYTRAVDWWGLGVLIYE
|.| .| ||.| ..|.|.|||..  |.||||| .|.||| || || .|||| | ..|  |  .. .|||||| .|||..|  . ....|||| .|..|||
FSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYE

MLVGESPFPGEDEEEVFDSIVNDD---VRYPRFLSSEAISIMR-KLLRRNPERRLGAGERDAEDIKRQPFF
|..|  ||  .. .. |..| . .   . ||  .||.. ..   ||| .||. ||| .  ..|.||. |.|
MVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase AqueK022.AA RSK 894-1150 40 2e-95 323.35 In-house 1-278 (278) Show / Hide 
Range on Protein: 894-1150
Range on HMM: 1-278/278
Sequence Identity: 40% (113 aa)

IAVLGRGHFGKVLLAEDK---NTKELVAVKVLKKGDIISRDE-VESLMSEKRIFEKINAVRHPFLVNLHCCFQSENNVCFVMEYACGGDLMMHIH-QDI-
. |||.| .||| |   .   .|. . |.|||||  |. |.  ..  | | .| | ..  .|||.|.||  || |  .  .|||  ||.| .|.  . . 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQ--QHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHF

--FKEPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDV---DGFVKVADFGLCKEG-MWYGSRTSTFCGTPEFLAPEVLT----DVSYTRAVDWWGL
  | | .||||.| .|| ...||. ||..||||..| |.|    .| .|. |||.||..   ....| |||.| |..|||.|.    .. ...|.||| |
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL

GVLIYEMLVGESPFPG---EDEEEVFDSIVNDD--VRYP--RFLSSEAISIMRKLLRRNPERRLGAGERDAEDIKRQPFF
|||.||||.| .|| |   .. .|... | . .  .. |   .|| || .. ||.| |.|..|||.| .|||.||. |.|
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase AqueK022.AA Pkinase 891-1150 30 9.3e-88 302.66 Pfam 1-293 (293) Show / Hide 
Range on Protein: 891-1150
Range on HMM: 1-293/293
Sequence Identity: 30% (93 aa)

YKFIAVLGRGHFGKVLLAEDKNTKELVAVKVLKKGDIISRDEVESLM-SEKRIFEKINAVRHPFLVNLHCCFQSENNVCFVMEYACGG----DLMMHIH-
|... ..|.| ||.| .. .|.| ..||||..|| .. |  ... .  || .|  ..|   ||. | |...|........||||. ||    ||. .|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

--QDIF--KEPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFV----KVADFGLCKEG-MWYGSRTSTFCGTPEFLAPEVLT-DVSYTRAVDW
  .  |   |  ..||.  .. ||.|.|..||..||||..|.|.| .| .    |..||||.|      .| ..||||||...||||.  .  |...||.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WGLGVLIYEMLVGESPFPGE------DEEEVFDSIVNDDVRYPRFLS---------------------SEAISIMRKLLRRNPERRLGAGERDAEDIKRQ
|..|...|||| |. ||||.      |. .... |   ....... .                     .|........|...|..|..     ||.|.  
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQH

PFF
|.|
PWF
Kinase AqueK022.AA Pkinase_Tyr 891-1103 30 8.9e-27 91.31 Pfam 1-228 (270) Show / Hide 
Range on Protein: 891-1103
Range on HMM: 1-228/270
Sequence Identity: 30% (71 aa)

YKFIAVLGRGHFGKVLLAEDK----NTKELVAVKVLKKGDIISRDE--VESLMSEKRIFEKI-NAVRHPFLVNLH-CCF-QSEN-NVCFVMEYACGGDL-
 .|. .||.|.||.| ... |    |||  ||||.||     . ..   |..|.| .|  .. .   || .|.|. .|  |.|  ... ||||...||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGH---HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

-MMHIH---QDIFKEPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFVKVADFGLCKEG-----MWYGSRTSTFCGTPEFLAPEVLTDVSYTR
   . |   .. .. .. . ... .  |..||...... |||   | |.. ...||..||||..         | .|...       .|||.. .  .| 
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGK-LPIKWMAPECINYGKFTT

AVDWWGLGVLIYEMLV-GESP-FPGEDEEEVFDSI
. | |  |||..|..  ||.| .|| . |||.. |
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase AqueK022.AA S_TK_X 1151-1215 37 3.5e-22 80.94 SMART 1-79 (79) Show / Hide 
Range on Protein: 1151-1215
Range on HMM: 1-79/79
Sequence Identity: 37% (30 aa)

KHIDWEKLLR--REVKPPFKPKLE----GRLDISNFDDEFTREDPIFTPPKNPRPLKAKEQK--------LFRGFEYSA
..|||.||..  .|..||||||.     .  |.||||.|||.|.|  ||.  |    . ...         |||| |..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase AqueK022.AA TyrKc 891-1144 24 3e-17 56.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 891-1144
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

YKFIAVLGRGHFGKVLLAEDKNTKELVAVKVLKKGDIISRDEVESLMSEKRIFEKI--NAVRHPFLVNLH-CCFQSE------NNVCFVMEYACGGDLMM
 ... .||.|.||.| ... |   . ||||.||..       .| .|.| ||  |.  .   || .|.|. .| |..        .. ||||...|||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGH---HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

HIHQDI--FKEPRACFYAACVVLGLQYLHENGIVYRDLKLDNLLLDVDGFVKVADFGLCKEGMWY---GSRTSTFCG----TPEF------LAPEVLTDV
...     .. .  . ..  .  | .|||..... |||   | |.. .. ||..||||....  .   | ....          .      .|||.. . 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

SYTRAVDWWGLGVLIYEML-VGESPFPG-----EDEEEVFDSIVNDDVRYPRFL---------SSEAISIMRKLLRRNPERRLGAGERDAEDI
 .| . | |  ||...|..  |..| ||      . .||.  . . . . .            ..|  .||..  ...|| |    |   |..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase AqueK022.AA Pkinase_C 1170-1217 39 9.6e-16 58.63 Pfam 1-46 (46) Show / Hide 
Range on Protein: 1170-1217
Range on HMM: 1-46/46
Sequence Identity: 39% (19 aa)

KLEGRLDISNFDDEFTREDPIFTPPKNPRPLKAKEQKLFRGFEYSADW
......|.||||.|||.|.|  ||   .| . . .| .|||| |....
QVKSPTDTSNFDPEFTDEPPMDTP-PDWR-MSSGDQEPFRGFTYVNPD