Gene AqueK076 (A.queenslandica)

AqueK076

Species: A.queenslandica
Alias: AqueK076
External Links:
Annotation:

Classification

Group: CAMK
Family: MLCK

Sequence

Name Sequence Type Origin Length Description Download
AqueK076.AA Protein None 466 None Fasta, JSON
AqueK076.kin_dom Protein Kinase Domain None 138 None Fasta, JSON

Protein domain

Protein domains of AqueK076.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IG AqueK076.AA IG 90-173 18 1.2e-11 45.89 SMART 1-58 (58) Show / Hide 
Range on Protein: 90-173
Range on HMM: 1-58/58
Sequence Identity: 18% (16 aa)

LSDESILEGQSVVFSCKLKHDYLDKDVKWFINDGVIGQNCSITTKSQDCVLQIDNISQKDE---GTYTCKVYVKDQFCQ-SSAKLMVV
 .  .  ||..|...|  .       ..|.                    |.| |..  |.   |||.| .  . |  .  ...| | 
PP-VTVKEGETVTLTC-VS------QIWWY--------------------LTI-NVQPEDSQQHGTYYCQAT-HGQYWSIQGTTLTVQ
I-set AqueK076.AA I-set 84-172 24 6e-09 32.87 Pfam 1-92 (92) Show / Hide 
Range on Protein: 84-172
Range on HMM: 1-92/92
Sequence Identity: 24% (23 aa)

PVIAEPLSDESILEGQSVVFSCKLKHDYLDKDVKWFINDGVIGQ---NCSITTKS-QDCVLQIDNISQKDEGTYTCKVYVKDQFCQSSAKLMV
|..  ...|  . ||... |.|. . |  . .| || ..  . .    ...| .  ... | |.|. . |||.|||..  .   ....|.| |
PKFTQKPKDVEVQEGETARFECQVTGD-PPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV
V-set AqueK076.AA V-set 82-172 17 4.1e-07 26.35 Pfam 1-128 (128) Show / Hide 
Range on Protein: 82-172
Range on HMM: 1-128/128
Sequence Identity: 17% (23 aa)

PVPVIAEPLS----DESILEGQSVVFSCKLKHDY----LDKDVKWFI-NDG-------------------------VIGQNCSITTKSQ--DCVLQIDNI
...| ..| .      .  ||||| ..|... ||     . .. |.   .                          .   ......  .  |. |.| |.
QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL

SQKDEGTYTCKVYVK-DQFCQSSAKLMV
.  |.|||.| |.    .  ... .|.|
QPSDSGTYYCAVWNCNEDYFGHGTRLTV
IGc2 AqueK076.AA IGc2 96-162 23 4e-06 27.44 SMART 1-56 (56) Show / Hide 
Range on Protein: 96-162
Range on HMM: 1-56/56
Sequence Identity: 23% (16 aa)

LEGQSVVFSCKLKHDYLDKDVKWFINDGVIGQNCSITTKSQDCVLQIDNISQKDEGTYTCKVYVKDQ
.|||||.. |.    . | ...|.  .  .           .  |.| |..  |.|.|||..  .  
HEGQSVTLTCP-ATGNPDPNIHWYK-GQPLP---------WNWTLTIKNVTPEDSGYYTCYARNPWG
FN3 AqueK076.AA FN3 176-257 25 5e-16 60.5 SMART 1-69 (69) Show / Hide 
Range on Protein: 176-257
Range on HMM: 1-69/69
Sequence Identity: 25% (25 aa)

PNAPGK---PHVQKITST------SVSLSWNLPFDGHSPVKLFIVECKDKITNKWSTLTKRIFEPSTIIDDLVPA----TEYVFRVIAAND--IGNS
| .|.    ..|  .|||      ||.|||. |          ||...                   ....|.|     |||.|||.| |.   | .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Kinase AqueK076.AA MLCK 286-409 28 1.7e-35 90.56 In-house 1-128 (257) Show / Hide 
Range on Protein: 286-409
Range on HMM: 1-128/257
Sequence Identity: 28% (37 aa)

YLLKNEIAKGMFGTVYKCLHKGTQQIYAAKLIPI--NLQINHCQNELDILALICHPNIVQLSAAYLSHQHFIIVMQYIQGLSPLTYFNERN--SSEHDIA
|  . |...| ||.|..|  | |....||| |..         .|| .|.    |||..|. .|. .   .. .| ||.|   ........   .| ...
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI

KFCRELCCGLKHLHDHGIVHLAIKPDSV
.. | .| |..|.|...|||| .||. .
HYMRQICEGVHHMHWQNIVHLDLKPENI
Kinase AqueK076.AA CAMK 291-423 16 1.2e-30 95.45 In-house 1-238 (425) Show / Hide 
Range on Protein: 291-423
Range on HMM: 1-238/425
Sequence Identity: 16% (40 aa)

EIAKGMFGTVYKCLHKGTQ------------QIYAAKLIPINLQI------------------------------NHCQNELDILAL-------ICHPNI
.. .| ||.|..| || |.            | .|.| |. .                                    ..|..|. .       . ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLSAAYL------------SHQH--------FIIVM---QYIQGLSP----LTYFNERNS----------------SEHDIAKFCRELCCGLKHLHDHG
..|  .|             . ..        ...||    |..|       . |  |. .                .|.. ... | .|......|.|.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHLAIKPDSVYVVPNSFD--------------FTVKLI
|||. .||. . .. |. |              ...|.|
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKII
Kinase AqueK076.AA AGC 286-401 19 6e-30 73.3 In-house 1-177 (395) Show / Hide 
Range on Protein: 286-401
Range on HMM: 1-177/395
Sequence Identity: 19% (35 aa)

YLLKNEIAKGMFGTVYKCLHK------GTQQIYAAKLIPINL--------QINHCQNE------------LDILALIC----------HPNIVQ-LSAAY
. ..  | || ||.|| . .|      .|...|| | .            .. | ..|             .||...           ||.||. |  ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

LSHQH--FIIVMQYIQ----------GLSPLTYF----NERNSSEHDIAKFCRE-------LCCGLKHLHD-HGIVH
 . .|    .||.|..          |.  ...     .|.  .|  .  .. |       ....| .||. .||.|
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIH
Pkinase AqueK076.AA Pkinase 286-407 30 7.4e-27 96.04 Pfam 1-137 (293) Show / Hide 
Range on Protein: 286-407
Range on HMM: 1-137/293
Sequence Identity: 30% (42 aa)

YLLKNEIAKGMFGTVYKCLHKGTQQIYAAKLIPINLQINHCQN-------ELDILALICHPNIVQLSAAYLSHQHFIIVMQYIQG-LSPLTYF------N
| ..  | .| ||.|||| ||||..|.| | |.    ......       |. |.. ..|||||.|  .. ...|  .|| | .| |. .  |      .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

ERNS--SEHDIAKFCRELCCGLKHLHDHGIVHLAIKPD
...   ||... ........||...|..||.|  .||.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPE
Kinase AqueK076.AA Trio 286-407 27 1.6e-25 61.79 In-house 1-124 (258) Show / Hide 
Range on Protein: 286-407
Range on HMM: 1-124/258
Sequence Identity: 27% (34 aa)

YLLKNEIAKGMFGTVYKCLHKGTQQIYAAKLIPINLQI-NHCQNELDILALICHPNIVQLSAAYLSHQHFIIVMQYIQGLSPLTYFNERNS-SEHDIAKF
|  ..||. | |. | .| ||.|.   ||| ||  .      . |...|.   || ...| ..|... | |..   . .   | .  .. | .| ... .
YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLMRWGSYCESEVKTY

CRELCCGLKHLHDHGIVHLAIKPD
 ...  ..  || ..| || |||.
MWQMLEAVHYLHNCHILHLDIKPE
Kinase AqueK076.AA STE 286-423 22 4.9e-23 78.25 In-house 1-189 (359) Show / Hide 
Range on Protein: 286-423
Range on HMM: 1-189/359
Sequence Identity: 22% (44 aa)

YLLKNEIAKGMFGTVYKCLHKG---------------TQQIYAAKLIPINLQ-------------------INHCQNELDILALIC--HPNIVQLSAAYL
. .  .| || ||||||....                |..|.| | .... .                   ..  ..|..|.      |||||.   .|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SH-------QHFIIVMQYIQGLSPLTYFN---ERNSS------------EHDIAKFCRELCCG-LKHLHDHGIVHLAIKPDSVYVVPNSFDFTVKLI
         ..  |.| |. | |     .   ... .            |. ||..||... | |..||.|.|.|  |||. . .        |||.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLC
Kinase AqueK076.AA TKL 292-411 18 2.4e-19 66.35 In-house 1-173 (364) Show / Hide 
Range on Protein: 292-411
Range on HMM: 1-173/364
Sequence Identity: 18% (33 aa)

IAKGMFGTVYKCLHKGTQ--------QIYAAKLIPI----------------------------NLQINHCQNELD-ILALICHPNIVQLSAAYLSHQH-
| .| ||.|||  ..|.         .  | | ...                            . ... . .|   ..  ..||||||. .. .. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FIIVMQYIQGLSPLTYFNERNSSEHDIAKFCRELCCGLKHLHDHG--------IVHLAIKPDSVYV
            . |||.|..| | | |..      | . ..... ..|. .|| ..        |.|  .|.. . |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILV
Kinase AqueK076.AA STE20 286-409 29 1.8e-17 60.66 In-house 1-148 (288) Show / Hide 
Range on Protein: 286-409
Range on HMM: 1-148/288
Sequence Identity: 29% (44 aa)

YLLKNEIAKGMFGTVYKCLHKGTQQI----YAAKLIPINLQ------INHCQNELDILALICHPNIVQLSAAYLSH----QHFIIVMQYIQG--LSPLTY
| |  .| .| .|.|||. || |...    .| | .... .      ..  |.| .|..   |||||.   .|| .    ..  ||| | .|  |. .  
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

FN-ERNS-------SEHDIAKFCRELCCGLKHLHDHGIVHLAIKPDSV
.. ...        .|  ||  |||.. ||..|| ..|.|  || | .
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNI
Kinase AqueK076.AA Ciliate-E2 286-407 21 2.3e-17 56.12 In-house 1-190 (365) Show / Hide 
Range on Protein: 286-407
Range on HMM: 1-190/365
Sequence Identity: 21% (40 aa)

YLLKNEIAKGMFGTVYKCLH-----------------------KGTQQIYAAKLI-----PINLQINHCQ----------NELDILALICHPNIVQLSAA
| . . | .| ||.|||| .                       | ...||| | .      . .|..|            ||. || .. ||||...  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YL--SHQHFIIVMQYIQGLSPLTYFNERNSS------------EHDIAKFCRELCC---------------GLKHLHDHG-IVHLAIKPD
.   . ... .|| |.|| . . | .... .            |  |... ....                .|..||  . |.|  |||.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPE
Kinase AqueK076.AA ULK 286-407 27 6.9e-17 55.56 In-house 1-159 (329) Show / Hide 
Range on Protein: 286-407
Range on HMM: 1-159/329
Sequence Identity: 27% (44 aa)

YLLKNEIAKGMFGTVYKCLHKGT----QQIYAAKLIPIN--LQINH----------CQNELDILALIC--------HPNIVQLSAAYLSHQH--FIIVMQ
| |.... || ||.|||  .| |    ....|.| |...   |.|.           .|| .|.  .         |||||.|   . . .|  . |.| 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YIQGLSPLTYFNER-----------NSSEHDIAKFCRELCCGLKHLHDHGIVHLAIKPD
| .|    .| ...           . ||  . .|.. .. |.|.||.|.|.|  |||.
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQ
Kinase AqueK076.AA ULK 286-407 28 9.1e-17 56.07 In-house 1-155 (324) Show / Hide 
Range on Protein: 286-407
Range on HMM: 1-155/324
Sequence Identity: 28% (44 aa)

YLLKNEIAKGMFG-TVYKCLHKGT---QQIYAAKLIPINLQIN------------HCQNELDILALIC---HPN--IVQLSAAYLSHQH--FIIVMQYIQ
| |.... || || .|||  .| |   .|..|.| |... ...              .||  |.  .    |||  ||.|   . . .|  . |.| | .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GLSPLTYFNER----------NSSEHDIAKFCRELCCGLKHLHDHGIVHLAIKPD
|    .| ...          . ||  . .|.. .| |.|.||.|.|.|  |||.
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQ
Kinase AqueK076.AA S_TKc 286-465 20 3.6e-13 16.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 286-465
Range on HMM: 1-231/231
Sequence Identity: 20% (51 aa)

YLLKNEIAKGMFGTVYKCLHKGTQQIYAAKLIPINLQINHCQNELDILALICHPNIVQLSAAYLSHQHFIIVMQYIQG--LSPLTYFNERNS-------S
| . ..| || ||.|||| ||.|..|.| | |.     .| ..|..||    |||||.|  .. . .|. .|| |. |   . ..|  .|..       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

EHDIAKFCRELCCGLKHLHDHGIVHLAIKPDSVYVVPNSFDFTVKLI------------------------HLS------------------EAKFVHSD
| .........||.|...|.|||.|  .||. . .       ..|..                        .                    .  |   .
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP--Q

VKQLSCKVVTGYEEGF-----------RVRIRNLSISV-------QPRI
....  |..   .|.            . |.    .          | .
MQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK076.AA TyrKc 286-461 14 7e-06 -127.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 286-461
Range on HMM: 1-280/280
Sequence Identity: 14% (40 aa)

YLLKNEIAKGMFGTVYKCLHKGTQQIYAAKLIPINLQINHCQNELDILALI--CHPNIVQLSAAYLSH-------QHFIIVMQYIQGLSPLTYF--NERN
  |. ..  | ||.|||.  |   .  | | .  .  .    .|. |.  .   |||||.| .. ...       .   ||| |  . . . |   ....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

SSEHDIAKFCRELCCGLKHLHDHGIVH-------------L-----------AIKPD-------SVYVV-----PN--------------SFDFTVK---
 .  |  .||   .||  .||.....|             .           .|. |       ..|..      .                 || |   
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

---------LIHLSEAKFVH-----SDVKQLSCKVVTG-----YEE-------------------------GFRVRIRNLSISV
         .  . .           . ...  .| .|      ..                           | . ...    
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK076.AA Pkinase_Tyr 286-401 21 6.1e-05 17.35 Pfam 1-134 (270) Show / Hide 
Range on Protein: 286-401
Range on HMM: 1-134/270
Sequence Identity: 21% (29 aa)

YLLKNEIAKGMFGTVYKCLHK----GTQQIYAAKLIPINLQINH------CQNELDILALI-CHPNIVQLSAAYL-SHQH--FIIVMQYIQGLSPLTYFN
  .  .. .| ||.|||.  |    .|..  | | .. .    .       . |. |.  .  |||||.| .. .   ..   .||| | .. . |.|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

ER-----NSSEHDIAKFCRELCCGLKHLHDHGIVH
..     . . .|. ..|.. ..|. .|......|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH