Gene AqueK098 (A.queenslandica)

AqueK098

Species: A.queenslandica
Alias: AqueK098
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK7

Sequence

Name Sequence Type Origin Length Description Download
AqueK098.AA Protein None 341 None Fasta, JSON
AqueK098.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of AqueK098.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK098.AA CDK7 5-289 59 2e-238 643.25 In-house 1-288 (288) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-288/288
Sequence Identity: 59% (172 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIK-IGQRREARDGINRTALREIKLLQELHHPHILGLLDVLGHKSNISLIFDFMDTDLEMIIKDKSLLL
| |.. .|||||||||.| |.. .  |||.|||| .| | ||.|||||||.||||.|||..|. . ||.|...|||||.|.|||||.||| .|||||..|
YEKIKHIGEGQFATVYKACDHQTG-QIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIIL

PPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKAYGSPNRIMTHQVVTRWYRSPELLFGARLYSTGVDLWAVGCIIAEMLLR
 |  .||| .|.||||||.|..|||||||||||||.|..|.|||.|||||..||||||| ||||||||||.|||||||| | ||||.|.||||.|| .||
TPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLR

LPFLPGETDLGQLSTIFEFFGSPNEENWPSVKSLPDYVEFKPSPP---QSFRDVFSAAGDDLIHLLESCMKLDPSKRCTASQALQSSYF
 |.|||. |. ||. ||.  | |.||.|| . ...||..||. |.     .|..|.||.|||..|..    ..|.||.|..|.|.. ||
VPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase AqueK098.AA CDK 5-289 40 2.8e-155 500.39 In-house 1-284 (284) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-284/284
Sequence Identity: 40% (130 aa)

YRKLDILGEGQFATVYRAEDTERD----NAIVAVKKIKIGQ--RREARDGINRTALREIKLLQELHHPHILGLLDVLGHK-----------SNISLIFDF
| ||. .||| ...||.| |....    . ||| |||.. .  |.|...|.. ||.|||.||.|| ||.|  |.||  .|           ......|..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MDTDLEMIIKDKSLLLPPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGV-----LKITDFGLAKAYGS------PNRIMTHQVVTRWYRSPE
||.||  ...          .| | ...|.||.|.| .||.||||||.|.|||..|.     |||.|||||.|.|.      ||| .||.|||.|||.||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLFGARLYS--TGVDLWAVGCIIAEMLL---RLPFLPGETDLGQLSTIFEFFGSPNEENWPSVKSLPDYVEFKPSPPQSFRDVFSAAGDDLIHLLESCMK
||.|.. ||  |..|.|.||||.|||..   | |..||.... ||  ||...|.|.|.|||.|..||||                       .||.... 
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------DLLNKMLC

LDPSKRCTASQALQSSYF
.||.||..|.||||. ||
YDPKKRISAEQALQHPYF
Kinase AqueK098.AA CMGC 5-289 25 9.40000000001e-132 435.61 In-house 1-513 (513) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-513/513
Sequence Identity: 25% (133 aa)

YRKLDILGEGQFATVYRAEDTE-------------RDNAIVAVKKIKIGQRRE-------ARDGINRTALREIKLLQEL-----------------HHPH
| ... .||| ...||.. |..             ..| |||.||||  .  |       ..||....||||||.|..|                 ||..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ILGLLDVLGHKS-----------------NISLIFDFMDTDLEMIIKDKS--------LLLPPGV------------VKAYS------LMILQGLE--YL
|..|.|.. ||                  .. |.|..||.||  .||...        . |.. .            .| ..       .||.||.  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HAHW--ILHRDLKPNNLLINKD--------------------GVLKITDFGLAKAYGSP---------------------NRIMTHQVVTRWYRSPELLF
| ||  |.|||||| |.|||..                    |.||| |||||..|...                     || .||.|||||||.||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GARLYS---------TGVDLWAVGCIIAEMLLR--------LPFLPGETD-----------LGQLSTIFEFFGSPN---------------EENWPSVKS
|.. |.         |..| |.||||.|||...         |. ||...           . ||  ||. .|.|.               ||.||....
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

LPDYVE---------------------------FKPSPPQSFRDVFSA-----------------------------------AGDDLIHLLESCMKLDP
||.|                             |.. ||......|                                     . ...|.||. ....||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

SKRCTASQALQSSYF
.|| ||.||||  ||
DKRITAEQALQHPYF
Kinase AqueK098.AA CDC2 5-289 41 9.60000000001e-114 351.06 In-house 1-301 (301) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-301/301
Sequence Identity: 41% (125 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIKIGQRREARDGINRTALREIKLLQELH-HPHILGLLDVLGHKSNISLIFDFMDTDLEMIIK-DKSL-
| |.  .||| .  ||...|.. .  |||.|||.. |  |   |.  ||.||| .|.||  || |  | ||.   ... ..|...| ||    .  ..  
YQKIEKIGEGTYGVVYKCKDMQTNQ-IVALKKIRLEQEDEGD-GVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKN

-LLPPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKAYGSPNRIMT--HQVVTRWYRSPELLFGARLYSTGVDLWAVGCIIA
  .|| .|| |   ||||....|.. |.|||||| |.||.|.|..|| |||||.| | | |  |  | |||.|||.||.|.|.. |||.||.|..|||.|
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EM---LLRLPFLPGETDLGQLSTIFEFFGSPNEENWPSVKSLPDYVEFKPS-PPQSFRDVFSA---------AGDDLIHLLESCMKLDPSKRCTASQALQ
||     . |. .|.    ||  ||...|.|||..||.|..|||| .  |  .|| .....           . .. | ||..   .||.|| .| .|||
EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

SSYF
  ||
HPYF
Kinase AqueK098.AA CDK5 5-289 39 9.1e-104 328.81 In-house 1-287 (287) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-287/287
Sequence Identity: 39% (115 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIKIGQRREARDGINRTALREIKLLQELHHPHILGLLDVLGHKSNISLIFDFMDTDLEMIIKDKSLLLP
| |.. .||| ..|||.| . |    ||| |.... .  |   |.  ||.||| ||.|| |. |  | ||.     . |.| |.| ||   . .    . 
YEKMEKIGEGTYGTVYKARNKET-HEIVALKRVRLDSEDE---GVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMD

PGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKAYGSPNRIMTHQVVTRWYRSPELLFGARLYSTGVDLWAVGCIIAEML-LR
. ..| . .  |.||.. |.| .||||||| |||||| | ||  ||||| |.| | |  .| ||| ||| |  |.|...||| .|.| .|||.|||    
MHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAG

LPFLPGETDLGQLSTIFEFFGSPNEENWPSVKSLPDY----VEFKPSPPQS-FRDVFSAAGDDLIHLLESCMKLDPSKRCTASQALQSSYF
 |  ||  .  ||  ||.  |.|.|..|||.  ||||    ... . |..  .  .       .  ||.  ....| .| .| .||.  ||
RPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase AqueK098.AA S_TKc 5-289 28 7.4e-94 319.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-231/231
Sequence Identity: 28% (85 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIKIGQRREARDGINRTALREIKLLQELHHPHILGLLDVLGHKSNISLIFDFMDT---DLEMIIKDKSL
|..|...|.| |..||.. ... .. |||.|.||            ....|||..|.. |||.|  |.||  . ... ......|.   ||  .||..  
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

L-----LPPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKAYGSPNRIMTHQVVTRWYRSPELLFGARLYST-GVDLWAVGC
      .|. ... |   |...|||.| |.|.|||||| |.|...  ..||.|||||. .       |....|.||..||.|     |..  .| |..||
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC

IIAEMLL-RLPFLPGETDLGQLSTIFEFFGSPNEENWPSVKSLPDYVEFKPSPPQSFRDVFSAAGDDLIHLLESCMKLDPSKRCTASQALQ-------SS
|..|||  . ||        |. ..|.  |                                   ........ |.. ||.|| || .|||         
ILYEMLCGYPPFP-------QMQMMFKKIG----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

YF
.|
WF
Kinase AqueK098.AA Pkinase 5-289 32 2.3e-91 314.61 Pfam 1-293 (293) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-293/293
Sequence Identity: 32% (98 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIKIGQRREARDGINRTALR--EIKLLQELHHPHILGLLDVLGHKSNISLIFDFMDT-----DLEMIIK
|... ..|.| |..||.. .      |||||.||    |..... ..|..|  ||.....|.||.|. |.|.   |..| .......      ||  .|.
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKK---RHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

-DKSLLL--PPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGVL----KITDFGLAKAY-GSPNRIMTHQVVTRWYRSPELLFGARLYSTGVD
 ...  .  .. ..| | . ||.||||.|...|.|||||| |.||...|..    ||.|||||| .   .|. ||. ..|.||..||.. |.. |.. ||
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

LWAVGCIIAEMLLRLPFLPGE----TDLGQLSTIFEFFGSPNEENWPSVKSLPDYVEFKPSPPQSFRDVFSAAGDDLIHLLESCMKLDPSKRCTASQALQ
 |..|||..|||.. |  ||.    . . |.  |..  | |....||   | ...  |.. ... .. .  .. .........| ..||.||.|| |.||
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-WHF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQ

SSYF
. .|
HPWF
Kinase AqueK098.AA PITSLRE 5-289 37 9.4e-89 301.17 In-house 1-295 (295) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-295/295
Sequence Identity: 37% (110 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIKIGQRREARDGINRTALREIK-LLQELHHPHILGLLDVL--GHKSNISLIFDFMDTDLEMIIKDKS-
. .|.  .|| .  |||| |.. |  ||| |..|.....| ..|.  |.||||. .| .| || |  .. ..    .  | ....... ||  ..   . 
FQCLNRIHEGTYGVVYRAKDKRTDE-IVALKRLKMERQKE-KEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKR

--LLLPPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKAYGSPNRIMTHQVVTRWYRSPELLFGARLYSTGVDLWAVGCIIA
      || .|   .  | | |..| .||.|||||  |||..  |.||| |||||  |||| .  |  ||| |||.|||| |...||| ||.| |||| |
RNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFA

EMLLRLPFLPGETDLGQLSTIFEFFGSPNEENWPSVKSLPD--YVE-FKPSPPQSFRDVFS---AAGDDLIHLLESCMKLDPSKRCTASQALQSSYF
|...  | ..|. .. |.  ||  .| |.|  || ...||   ... |.. |.   |  |       |    ||     ..| .| |||.||.  .|
EFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase AqueK098.AA CCRK 5-289 44 2.7e-82 279.71 In-house 1-285 (285) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-285/285
Sequence Identity: 44% (128 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIKIGQRREARDGINRTALREIKLLQELHHP-HILGLLDVLGHKSNISLIFDFMDTDLEMIIKDKSLLL
|  || .|||    |..|   |    |||.||. .   |   |||  .|||||| |||.     .  | ||  | .   |.|.||  ||  ....    |
YCILDRIGEGAHGIVFKAKHVETGE-IVALKKVAL---RRLDDGIPNQALREIKALQEIEDNQYVVQLKDVFPHGTGFVLVFEFMLSDLAEVVRHAQRPL

PPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKAYGSPN-RIMTHQVVTRWYRSPELLFGARLYSTGVDLWAVGCIIAEMLL
 .  ||.| .|.|.|. . |.  |.|||||| |||| . | ||| |||||. .   . |  |||| ||||| ||||.||| |  ||||||||||. |.| 
AEAQVKSYMQMLLKGVAHCHENNIMHRDLKPANLLISESGHLKIADFGLARVFSNDEGRQYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLN

RLPFLPGETDLGQLSTIFEFFGSPNEENWPSVKSLPDY--VEFKPSPPQSFRDVFSAAGDDLIHLLESCMKLDPSKRCTASQALQSSYF
  |  ||| |. ||  .    | |..  || .| ||||  . ||  ||    .|   |  . . ||.  .   | .| .|||||   ||
NSPIFPGENDIEQLCCVLRILGTPTPKVWPEMKDLPDYNKISFKEQPPMPLEQVVPDASPQALDLLKQFLVYPPRQRIAASQALLHQYF
Kinase AqueK098.AA CDK10 5-289 38 1.3e-80 274.12 In-house 1-285 (285) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-285/285
Sequence Identity: 38% (111 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIKIGQRREARDGINRTALREIKLLQELHHPHILGLLDVL--GHKSNISLIFDFMDTDLEMIIKDKSLL
. ||  .||| .  |||| |. | . |||.||... .    .||.   .||||.|| ...|. |  | .|    |   | |. .. . ||  ..   .  
FEKLNRVGEGTYGIVYRARDM-RSDEIVALKKVRMDK---EKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQP

LPPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKAYGSPNRIMTHQVVTRWYRSPELLFGARLYSTGVDLWAVGCIIAEMLL
     ||   | .|.|| ||| ....|||||  |||.  .| .|. |||||..|| | . || ..|| ||| ||||.|.|   | .|.||||||..|.|.
FTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLV

RLPFLPGETDLGQLSTIFEFFGSPNEENWPSVKSLPDYVEF--KPSPPQSFRDVFSAAGDDLIHLLESCMKLDPSKRCTASQALQSSYF
  | .||  .. |.  | .  |.|.|. ||    ||   .|  |  |    .  |   ..   .||.  .  .| || || ..|.||||
HKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase AqueK098.AA CDK-Unclassified 5-289 28 1.1e-79 261.8 In-house 1-324 (324) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-324/324
Sequence Identity: 28% (95 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIKIGQRREARD----------GINRTALREIKLLQELHHPHILGLLDVLGHKSNIS------------
|| . ..||| |. |. | |... . .|| ||| . .     .           .  |..|||..|| ..|  |. ..|.    .  |            
YRMQCKYGEGTFGCVCKAIDFQT-QKHVAIKKIMVNNKK---GNKCKHILPLLNSKITDQREISCLQNCNHMNIIKFMDMHYDHDRCSKNPYYDNLHPSF

-LIFDFMDTDLEMIIKDKSLLLPPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDG-----VLKITDFGLAKAYG------------SPNRIMT
 .. . |. ..    .     |    .. . . .| |. |||   | |||.|| |..|   .     .||| |||.|  |              |..  .
YMVMEYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYS

HQVVTRWYRSPELLFGARLYSTGVDLWAVGCIIAEMLLRLPFLPGETDLGQLSTIFEFFGSPNEENWPSVKSLPDY--VEFKPSPPQS----FRDVFSAA
 ||.|||||.|||||| . | |||| |..|||.||.. . | ..| |.. |.. ||   |.|.|..||.  ..|||  . ||....      |    .| 
TQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRTEIEQMHHIFKMLGTPCEDMWPDWRYMPDYCKIFFKYKQKFHWWNRFPKCKHAS

GDDLIHLLESCMKLDPSKRCTASQALQSSYF
. ... ..     ..| .| .....||...|
ENNCEFQM---VMYQPYNRWKCMEILQHPWF
Kinase AqueK098.AA MAPK 115-289 36 1.3e-61 211.03 In-house 124-328 (328) Show / Hide 
Range on Protein: 115-289
Range on HMM: 124-328/328
Sequence Identity: 36% (75 aa)

ILQG--LEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKAYGS-PN-------------RIMTHQVVTRWYRSPELLFG--ARLYSTGVDLWAVGCI
|| |  | |.|   ..|||||| |.|.|... ||| |||||    .  .             . ||  |.|||||.||....  .. |...|| |.||||
ILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCI

IAEMLL-RLPFLPGETDLGQLSTIFEFFGSPNEENWPSVK-S-LP-DYVE----FKPSPPQSFRDVFSA----AGDDLIHLLESCMKLDPSKRCTASQAL
 ||||  | |..||.  . |.  |.|. |.| || .  .. |  . .|..    ... |.......|.     | .. |.|||    .||.|| |. .||
FAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEAL

QSSYF
|  ||
QHPYF
Kinase AqueK098.AA MAPK 5-97 27 3.3e-17 55.87 In-house 1-107 (328) Show / Hide 
Range on Protein: 5-97
Range on HMM: 1-107/328
Sequence Identity: 27% (31 aa)

YRKLDILGEGQFATVYRAEDTE-----RDNAIVAVKKIK--IGQRREARDGINRTALREIKLLQEL-HHPHILGLLDVLGHK-----SNIS------LIF
|. |  .|.| . .|  | |..     ... .||.|||         ..      ..||||||... ||. | .|||..  .     ....      ...
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK-----RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVM

DFMDTDLEMIIK
..|.|||  |||
ELMETDLHQIIK
Kinase AqueK098.AA TyrKc 5-289 21 6.2e-16 34.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-289
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

YRKLDILGEGQFATVYRAEDTERDNAIVAVKKIKIGQRREARDGINRTALREIKLLQEL--HHPHILGLLDVLGHK-------SNISLIFDFMDT-DLEM
 .....||||.| .||... .      ||||..| .          .  .||.... .|  |||.|. |. |  ..         . ... .|.  ||  
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

IIKDKSLLLPPGVVKAYSLMILQGLEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKAYGSP-------NRIMT-----HQ--VVTRWYRSPELLFG
 ....   |..     ... | .| |||| . . ||||   | |...... ||.||||... ..          ...         .  ||. .|| .  
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-N

ARLYSTGVDLWAVGCIIAEMLLRLPFLPGETDLGQLSTIFEFFGSPNEE------NWPSVKSLPDYVEFKPSPPQ----SFRDVFSAAGDDLIHLLESCM
 . ..|  | |. |  . |                   || . ..| ..      ..  |  . .  .  | ||     ||      . |..  . ..| 
YGKFTTKSDVWSFGVCMWE-------------------IFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCW

KLDPSKRCTASQALQSSYF
. ||..|.| |.    ..|
HEDPEDRPTFSEI--HECF
Kinase AqueK098.AA Pkinase_Tyr 5-72 31 4.4e-07 24.61 Pfam 1-70 (270) Show / Hide 
Range on Protein: 5-72
Range on HMM: 1-70/270
Sequence Identity: 31% (23 aa)

YRKLDILGEGQFATVYRAEDT---ERDNAIVAVKKIKIGQRREARDGINRTALREIKLLQEL-HHPHILGLL
 ...  ||||.| .||... .   . ..  ||||..| |   |.   . .  .||.|.. .| |||.|. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN--CREDFMREAKIMKQLGHHPNIVRLY
Kinase AqueK098.AA Pkinase_Tyr 117-155 46 3e-06 21.74 Pfam 122-160 (270) Show / Hide 
Range on Protein: 117-155
Range on HMM: 122-160/270
Sequence Identity: 46% (18 aa)

QGLEYLHAHWILHRDLKPNNLLINKDGVLKITDFGLAKA
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KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD