Gene AqueK105 (A.queenslandica)

AqueK105

Species: A.queenslandica
Alias: AqueK105
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: PITSLRE

Sequence

Name Sequence Type Origin Length Description Download
AqueK105.AA Protein None 664 None Fasta, JSON
AqueK105.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of AqueK105.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK105.AA PITSLRE 329-613 69 3.8e-220 737.66 In-house 1-295 (295) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-295/295
Sequence Identity: 69% (204 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKME--KEREGFPITSLREISTLLKA-NHENIVNVREIVVGSNMDKIFIVMDYVEHDLKSLMETMK---
.. ||||.|||||||.||.| |||||||||.||||  ||.|||||||||||...|.| .|.|||||.|||.|||||||..||.|||||||||||.||   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

QPFLEGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPLKNYTPIVVTLWYRAPELLLGAKEYSTAIDVWSVGCIFAEL
|||..||.|.|..|||..|.|.|||||.||||||||||.|||||||..|||||||||||.| |||.||||||||||||||.|.|||..|.|||||||||.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

LQHKPLFMGKSEIDELNLIFKELGVPNESIWPGFGELPVAKKVQ-FTQQPLNNLRKRFP---MITKNGFVLLNKFFAYDPKRRVTAEDALKHEYF
.. |||| ||||||..| ||||.| |.|.||||. |||..|... |...| ||||||||    |. .|| |||..  |.||.| ||.|||||..|
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase AqueK105.AA CDK 329-613 45 3.7e-166 535.73 In-house 1-284 (284) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-284/284
Sequence Identity: 45% (145 aa)

YEWLNRIEEGTYGVVFRARDIRTD-----EIVALKKLKMEK-----EREGFPITSLREISTLLKANHENIVNVREIVVGSNMD---------KIFIVMDY
|| |..| |||||||..||| .|.     .||||||..||.     |.||||||..||||.| .  |.|||.........|||         |...|..|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

VEHDLKSLMETMKQPFLEGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGI-----LKVADFGLAREYGS------PLKNYTPIVVTLWYRAPE
..||||..|.          .|... |||...|..|.|||.|||||..|.|....|.     ||.|||||||..|.      |.. ||. ||||||||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLLGAKEYS--TAIDVWSVGCIFAELLQ---HKPLFMGKSEIDELNLIFKELGVPNESIWPGFGELPVAKKVQFTQQPLNNLRKRFPMITKNGFVLLNKF
||||.|.||  |.||.|||||||||...    ||||.|.|||| | .||. .| |.|..|||. .||                            ||||.
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKM

FAYDPKRRVTAEDALKHEYF
..||||.|..||.||.|.||
LCYDPKKRISAEQALQHPYF
Kinase AqueK105.AA CDK10 329-613 56 2e-150 506.04 In-house 1-285 (285) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-285/285
Sequence Identity: 56% (160 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKMEKEREGFPITSLREISTLLKANHENIVNVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKQPFLEG
.| |||. |||||.|.||||.|.|||||||| .|.||..| || .||||  |..  |||||...|.|||  .| ||.||.| | || ||.. | ||| | 
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQPFTET

EVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPLKNYTPIVVTLWYRAPELLLGAKEYSTAIDVWSVGCIFAELLQHKPL
.|| . .|.|.... ||||..|||||| ||||.. || .||||||||| || | |  || .|||||||||||||...  ||||.| |||| .||| ||||
QVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKPL

FMGKSEIDELNLIFKELGVPNESIWPGFGELPVAKKVQFTQQPLNNLRKRFPMITKNGFVLLNKFFAYDPKRRVTAEDALKHEYF
. | |||  ...| . || |.|.||||| .||....    .|| |||...|... . |  |||  | |.||.| |||..|. .||
MPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase AqueK105.AA CDC2 329-613 43 1.5e-138 428.71 In-house 1-301 (301) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-301/301
Sequence Identity: 43% (131 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKMEKEREG--FPITSLREISTLLKAN-HENIVNVREIVVGSNMDKIFIVMDYVEHDLKSLME-TMK--
|. ...| |||||||....| .|..|||||| . | | ||  .| |..||||.| . . |.|||  .....     |...| .|...||| .|.   .  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

QPFLEGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPLKNYTPI--VVTLWYRAPELLLGAKEYSTAIDVWSVGCIFA
... .  || ...|.|..||..| . |.||||| .|.|.. || .|.|||||||  | |...||.   ||||||||||.|||.| |||..|.||.|||||
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EL---LQHKPLFMGKSEIDELNLIFKELGVPNESIWPGFGELP--VAKKVQFTQQPLNNLRKR------FPMITKNGFVLLNKFFAYDPKRRVTAEDALK
|.    . ||||.|.||||.|  ||. || |||..|||  .||   ..  ....| | .. ..      . .....|. ||..  .||| .|..|..||.
EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

HEYF
| ||
HPYF
Kinase AqueK105.AA CMGC 329-613 27 8.49999999999e-134 442.46 In-house 1-513 (513) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-513/513
Sequence Identity: 27% (140 aa)

YEWLNRIEEGTYGVVFRARD--------------IRTDEIVALKKLK---MEK------EREGFPITSLREISTLLKAN-----------------HENI
|| ...| |||||||...||              ..|.||||.||.|   .|       |..||||..||||. | . |                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNVREIVVGSNMD---------------KIFIVMDYVEHDLKSLMETMK--------QPFLEGE------------VKTLL------IQLLKAVH--HLH
|. ..|.. .|.|               ....|..|..|||. ... ..        .|. | .            .| ..       |.|....  ..|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

DNW--IIHRDLKTSNLLLSHK--------------------GILKVADFGLAREYGSP---------------------LKNYTPIVVTLWYRAPELLLG
 .|  ||||||| .|.|..|.                    |.||..|||||| |...                     .. ||. |||.||||||.|||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

AKEYS---------TAIDVWSVGCIFAELLQ--------HKPLFMGKSE-----------IDELNLIFKELGVPN---------------ESIWPGFGEL
.|.|.         |.||.|||||||||...        .|||| |.||           || |..||| || |.               | .||.. .|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PVAKK-------------------------VQFTQQPLNNLRKRFPM-----------------------------------ITKNGFVLLNKFFAYDPK
|  .|                          .| ..| ..... ||                                    ... .. ||.| . |||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

RRVTAEDALKHEYF
.| |||.||.|.||
KRITAEQALQHPYF
Kinase AqueK105.AA CDK7 329-613 38 2.3e-127 341.35 In-house 1-288 (288) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-288/288
Sequence Identity: 38% (112 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLK----MEKEREGFPITSLREISTLLKANHENIVNVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKQP
|| .  | ||....|..|.|  |..||| || |     .  . |   | .|||  |    |.|... . |      . |  |.|. . ||    .  .  
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFM--HKSNIQLVFDFMDWDLEVVIKDKSII

FLEGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPLKNYTPIVVTLWYRAPELLLGAKEYSTAIDVWSVGCIFAELLQ
.   ..|   ...|. . ..| ||| |||||  |||..  |.||.||||||| |||| ..||. ||| |||||||| ||. | |..|.||||||||||. 
LTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELML

HKPLFMGKSEIDELNLIFKELGVPNESIWPGFGELPVAKKVQFTQQPL---NNLRKRFPMITKNGFVLLNKFFAYDPKRRVTAEDALKHEYF
  | . | |.|| |  ||. || |.|. ||.  ...    ..|...|      ||..|   .     |. . .. .| .|.|. ..||..||
RVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMM--DYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase AqueK105.AA CDK5 329-613 41 1.7e-115 366.53 In-house 1-287 (287) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-287/287
Sequence Identity: 41% (120 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKMEKEREGFPITSLREISTLLKANHENIVNVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKQPFLEG
|| ...| |||||.|..||.  | ||||||. ... | || | | .|||. |    |.|||    ..   .  |. .|  ..  |||  |. ..      
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEK--KLTLVFEFCDQDLKKYMDSCNGEMDMH

EVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPLKNYTPIVVTLWYRAPELLLGAKEYSTAIDVWSVGCIFAELL-QHKP
 .| .. |||| .   |.. . |||||  ||| . .|.|| ||||||| .| | ..|.  |||||||.|  |.|.| ||| ||.||.||||||.    .|
IIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRP

LFMGKSEIDELNLIFKELGVPNESIWPGFGELPVAK--KVQFTQQPLNN-LRKRFPMITKNGFVLLNKFFAYDPKRRVTAEDALKHEYF
|| | .. |.| .||| .| |.|. ||.  .||  |   .|.   |..  . .  |   ..|  ||.|   ..|. |..|..||.| ||
LFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase AqueK105.AA CRK7 329-613 37 1.3e-106 360.5 In-house 1-343 (343) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-343/343
Sequence Identity: 37% (127 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKMEKE---REGFPITSLREISTLLKANHENIVNVREIVVG------SNMDK--IFIVMDYVEHDLKSL
|| .. | ||||| |  |.. .| |.|||||..|. |   .||||||. |||  |   ||.|||| .|||.       .. .|  .. | .|. |||  |
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

METM-KQPFLEGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPL--KNYTPIVVTLWYRAPELLLGAKEY--------
.|    . | ....| .. |||  .  .|.. ..|||.| ||.|.  .|..| ||||||| | |    . ||  |.|||||.||||||...|        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------STAIDVWSVGCIFAELLQHKPLFMGKSEIDELNLIFKELGVPNESIWPGFGELPVAKKVQFTQQPLNNLR
                               ..||.||.|||..||.  ||.| |. |.. | .|.|  | ||   ||   .||  .     .|    ||
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

KRFP------MITKNGFVLLNKFFAYDPKRRVTAEDALKHEYF
. |       ...|  . || |  ..||| |.|||..| |..|
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase AqueK105.AA S_TKc 329-613 27 4e-92 313.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-231/231
Sequence Identity: 27% (83 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKMEKEREGFPITSLREISTLLKANHENIVNVREIVVGSNMDKIFIVMDYVEH---DLKSLMETMKQP-
|| |. | .|..|.|...|...|..|||.|..|         .. .|||. | | .|.|||.  .. .    |....||.|...   ||..... .. . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FLEGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPLKNYTPIVVTLWYRAPELLLGAKEYST-AIDVWSVGCIF
    | | ... .. |...|. ..|...||||||| .|.||..   .|..||||||..       | ...|.||.|||.|     |.. ..|.||.|||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

AELLQHKPLFMGKSEIDELNLIFKELGVPNESIWPGFGELPVAKKVQFTQQPLNNLRKRFPMITKNGFVLLNKFFAYDPKRRVTAEDALK-------HEY
.|.|  .|.|       .....|| .|                                    .. .  ...| . .||..| || .||.       |..
YEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

F
|
F
Kinase AqueK105.AA CDK4 329-613 39 9.3e-88 297.85 In-house 1-290 (290) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-290/290
Sequence Identity: 39% (116 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKMEKERE--GFPITSLREIS---TLLKANHENIVNVREIVVGSNMDK----IFIVMDYVEHDLKSLME
|. .. | || || |.||||. |  .||||. .   . |  | |.  .||||    | . .| |||   ..   .  |     | .|.  .. ||. ...
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

TMKQPFL-EGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPLKNYTPIVVTLWYRAPELLLGAKEYSTAIDVWSVGCI
 . .| . .  .| .  ||| .|  || . |||||||  |.|..  | .| |||||||.|..  .  ||.|||||||||| || .  | | .| ||||||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMA-LTPVVVTLWYRAPEVLL-QSYYNTPVDMWSVGCI

FAELLQHKPLFMGKSEIDELNLIFKELGVPNESIWPGFGELPVAKKVQFTQQPLNNLRKRFPMITKNGFVLLNKFFAYDPKRRVTAEDALKHEYF
|||.   .||| |.|| | |  ||.  | | |  ||   .  ..    | |.   ....  | . | |  ||.|   |....|..|. .|.| ||
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWP--RDVSLPWD-HFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase AqueK105.AA Pkinase 329-613 28 5.7e-86 296.71 Pfam 1-293 (293) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-293/293
Sequence Identity: 28% (88 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKMEKEREGFPITSLR--EISTLLKANHENIVNVREIVVGSNMDKIFIVMDYVEHDLKSLMETM-----
|. . .| .|..|.|...... | .|||.|..| ..|......| .|  ||. ... ||.|||  ....     |.| .||.|.|..|. .|. .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFDYIST

--KQPF--LEGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGIL----KVADFGLAREY-GSPLKNYTPIVVTLWYRAPELLLGAKEYSTAIDV
  . .|   | |.|  . |.|... ..|...||||||| .|.|....| .    |..|||||. .   .   .| ...|.||.|||...|...|....|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSVGCIFAELLQHKPLFMGK----SEIDELNLIFKELGVPNESIWPGFGELPVAKKVQFTQQPLNNLRKRFPMITKNGFVLLNKFFAYDPKRRVTAEDAL
||.|||..|.|  .|.| |.    . .|.. .|.. .| |... ||   . .  . ... . .   .... . .....  .... ...|||.| |||..|
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQIL

KHEYF
.|..|
QHPWF
Kinase AqueK105.AA PFTAIRE 329-613 39 9.7e-85 287.83 In-house 1-287 (287) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-287/287
Sequence Identity: 39% (114 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKMEKEREGFPITSLREISTLLKANHENIVNVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKQPFLEG
|| |..  ||.|  |.... . .  .||||  ....| || | |  || | |    | |||    |.         .|  ||. ||.  |.         
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQE-EGTPFTAIREASLLKNLKHANIVCLHDIIHTKET--LTFVFEYVHTDLCQYMDKHPGGMHPN

EVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPLKNYTPIVVTLWYRAPELLLGAKEYSTAIDVWSVGCIFAELLQHKPL
 |.  | |||      |   . |||||  |||.||.| || |||||||    | . |   ||||||| |  |||. |||| .|.| ||||| |... .|.
NVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPA

FMGK-SEIDELNLIFKELGVPNESIWPGFGELPVAKKVQFT--QQPLNNLRKRFPMIT--KNGFVLLNKFFAYDPKRRVTAEDALKHEYF
| |     | |..||| ||.|.|  |||  .||  |...|.       .|.. .| |    ... |..|.  . |. || |..|..|.||
FPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase AqueK105.AA Pkinase_Tyr 329-514 28 7.6e-16 54.28 Pfam 1-199 (270) Show / Hide 
Range on Protein: 329-514
Range on HMM: 1-199/270
Sequence Identity: 28% (60 aa)

YEWLNRIEEGTYGVVFRARDI----RTDEIVALKKL---KMEKE--REGFPITSLREISTLLKA-NHENIVNVREIVV--GS-NMDKIFIVMDYVEH-DL
 . .  . || .|.|....       |.  || |.|    |...  || |    .||.... .  .|.|||.   ...  |  |  .|.||| |..| ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF----MREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDL

KSLMETM---KQPFLEGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSPLKNYTPIVVTL-------WYRAPELLLGAK
..   .    |||.   .     .|  |.  .|... .||||| . | |...... |..||||||      . |  ....        |. ||| .   |
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYY-YRKRGGGKLPIKWM-APECINYGK

EYSTAIDVWS
 ..|. ||||
-FTTKSDVWS
Kinase AqueK105.AA TyrKc 329-613 20 3.5e-14 6.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 329-613
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

YEWLNRIEEGTYGVVFRARDIRTDEIVALKKLKMEKEREGFPITSLREISTLLKA--NHENIVNVREIVVGS-----NMDKIFIVMDYVEH-DLKSLMET
 . .  . || .|.|.... .   . || |.|| .. || |    .||.. . |   .|.|||.   ... .       . ..||| |..| |||.    
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDF----MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

MKQPFLEGEVKTLLIQLLKAVHHLHDNWIIHRDLKTSNLLLSHKGILKVADFGLAREYGSP------LKNYTP----IV---VTLWYRAPELLLGAKEYS
 .  .   .     .|  .   .||.. .||||| . | |...... |..||||.|. ..        . |..         . .   ||| .   ....
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

TAIDVWSVGCI------FAELLQHKPLF--MGKSEIDELNLIFKELGVPNE----SIWPGFGELPVAKKVQFTQQPLNNLRKRFPMITKNGFVLLNKFFA
|. |||| |        . .     . .  |  .|. |.    . .  | .    |                           |.  ..  . .  .  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------FVCCPDEMYQIMKQCWH

YDPKRRVTAEDALKHEYF
.||. | | ..   ||.|
EDPEDRPTFSEI--HECF