Gene AqueK132 (A.queenslandica)

AqueK132

Species: A.queenslandica
Alias: AqueK132
External Links:
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MAK

Sequence

Name Sequence Type Origin Length Description Download
AqueK132.AA Protein None 680 None Fasta, JSON
AqueK132.kin_dom Protein Kinase Domain None 301 None Fasta, JSON

Protein domain

Protein domains of AqueK132.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK132.AA MAK 73-307 52 5.3e-146 468.04 In-house 78-352 (352) Show / Hide 
Range on Protein: 73-307
Range on HMM: 78-352/352
Sequence Identity: 52% (143 aa)

VHALQRLK-HVNIIKATEIFR--DNNTLYFVFEYMRQNLYELIKSRGSNLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGH----------
| .|  |. | ||.|  |..|   |..|||||||| .|||...| |   .||| |.||| ||| |.  .||  | ||||.|||||.| |           
VKSLKKLNAHPNIVKLKEVIRDSENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMN

-------ELIKLADFGQAREIRSRPPYTDYVSTRWYRAPEVQLGSKNYNSPIDIWAVACIMSEVYSGRPLFPGSGTIDQVYKICGVLGTPTKAT------
       ||||.|||| ||||||.||||||||||||||||| | | .|.||||.||| ||| |.|. |||||||  |||..||| |||||.|..      
QIGYQDNELIKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTN

----------WGEGVGLAVSMSIRLPIMVP---TPLSALVPTASD-DGISVMKEMLQWNPRRRPTAKQVLMHKYF
          | .|  || .|  |.|  ||   .||. |.|..|  |.| .||.||||.| .||||.| . ..||
HITAPPPGGFWPDGYQLAHMMNFRFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase AqueK132.AA RCK 73-307 52 4.8e-144 460.12 In-house 48-298 (298) Show / Hide 
Range on Protein: 73-307
Range on HMM: 48-298/298
Sequence Identity: 52% (133 aa)

VHALQRLK-HVNIIKATEIFRDNN--TLYFVFEYMRQNLYELIKS--RGSNLFPEHV--VRNISYQIIQAVSYMHSQGLFHRDLKPENILCQG-------
. .| .|. | ||||  |..|||.  .|||||||| .|||...|.   .  ..|| .  ..|| |||.|. ..||..| ||||||||||.| |       
IKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFED

--HELIKLADFGQAREIRSRPPYTDYVSTRWYRAPEVQLGSKNYNSPIDIWAVACIMSEVYSGRPLFPGSGTIDQVYKICGVLGTPTKATWGEGVGLAVS
   ..||.|||| .|||||.||||||||||||||||. | . .||||.||||| ||| |.|. |||||||  ||| .||| |.|||.| .| .|. || .
QDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQ

MSIRLPIMVPTPLSALVPTASDDGISVMKEMLQWNPRRRPTAKQVLMHKYF
| ...|  ...||. |.| .| |.|..|..||||.|  |.||.|.| |.||
MNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase AqueK132.AA CMGC 7-307 23 3.5e-110 363.41 In-house 1-513 (513) Show / Hide 
Range on Protein: 7-307
Range on HMM: 1-513/513
Sequence Identity: 23% (127 aa)

YTFLKVLGDGTFGVVSLAKE--------------KETGNMVAIKKMKQDFLSWEECLKLKEVQVSELFVSPYIYKYGR-----------NDVHALQRLK-
|. .|..| ||.|||  ..               .||...|||||.|..|   |....                                 .  |..|. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKS-------------------TIEKDGFPIRALREIKILKHLNK

----------------HVNIIKATEIFRDNN-----------------TLYFVFEYMRQNLYELIKSRGS-------NLFPEHV------------VRNI
                | ||.|  .||...|                  ||.||||| ..||..||.          . ..| .            ....
NHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYF

S------YQIIQAVS--YMHSQG--LFHRDLKPENILCQGHEL--------------------IKLADFGQAR--EIRSRP-------------------
.      |||....   |.||..   .||||||||||                          .|..||| ||  ...|..                   
MIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPN

-PYTDYVSTRWYRAPEVQLGSKNYN---------SPIDIWAVACIMSEVYSG--------RPLFP-----------GSGTIDQVYKICGVLGTPT-----
 |||.||.||||||||. ||.|.|.         .|||.|.|.||. | | |        .||||           |. .||| .||. ||||||     
RPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQK

----------KA-------------------------TWGEGVGLAVSMSIRLPIMVPTPLSALVPT---------------------------------
          .                          .| |.. ..... .|.|   | |.. |.|                                  
GKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKR

--ASDDGISVMKEMLQWNPRRRPTAKQVLMHKYF
  .....|  .| |||..| .|.||.| | | ||
KCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase AqueK132.AA S_TKc 7-307 29 1.6e-91 311.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-307
Range on HMM: 1-231/231
Sequence Identity: 29% (93 aa)

YTFLKVLGDGTFGVVSLAKEKETGNMVAIKKMKQDFLSWEECLKLKEVQVSELFVSPYIYKYGRNDVHALQRLKHVNIIKATEIFRDNNTLYFVFEYMRQ
|..|...| |.||.| ....|.||  ||||..|                           .  |. .  |.. .| ||.|  ..|.| . ||.|.||. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDG

---NLYELIKSRGSNL----FPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGHELIKLADFGQAREIRSRPPYTDYVSTRWYRAPEVQLGSKN
   .|...||.||..     ||| ..| . |||..|. |.||.|  ||||||||||.     ||..||| ||..      | .. |.||.||||      
DLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----G

YNS-PIDIWAVACIMSEVYSGRPLFPGSGTIDQVYKICGVLGTPTKATWGEGVGLAVSMSIRLPIMVPTPLSALVPTASDDGISVMKEMLQWNPRRRPTA
|.  ..|.|.. ||. | ..|.|.||   ......|..|                                       |..... .. .||..|..||||
YGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA

KQVLM-------HKYF
 ..|        | .|
-EALQDEWDIKCHPWF
Kinase AqueK132.AA Pkinase 7-307 29 2.6e-87 301.17 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-307
Range on HMM: 1-293/293
Sequence Identity: 29% (94 aa)

YTFLKVLGDGTFGVVSLAKEKETGNMVAIKKMKQDFLSWEEC-----LKLKEVQVSELFVSPYIYKYGRNDVHALQRLKHVNIIKATEIFRDNNTLYFVF
|......| |.||.| ....| || .||.|..| .  .....     |                     . .. ..||.| ||..  ..|.|.. .|.|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---------------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVM

EYMRQ-----NLYELIK--SRGSNLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGHELI----KLADFGQARE--IRSRPPYTDYVSTRWY
||..       |...|.  ..|. .|.|...... |||.... |.||.|  ||||||||||.  .  |    |..||| |.   . . . .|... |.||
EYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWY

RAPEVQLGSKNYNSPIDIWAVACIMSEVYSGRPLFPGS----GTIDQVYKICGVLGTPTKATWGEGVGLAVSMSIRLPIMVPTPLSALVPTASDDGISVM
.|||| .|.. | ...|.|.. ||. |...|||.|||.    . .|| ..|| ..|.|..  | .      .. .|      . .. . . .|.......
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFI

KEMLQWNPRRRPTAKQVLMHKYF
| .|...| .||||.|.| |..|
KWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK132.AA CDK 76-307 32 3.7e-80 256.11 In-house 62-284 (284) Show / Hide 
Range on Protein: 76-307
Range on HMM: 62-284/284
Sequence Identity: 32% (84 aa)

LQRLKHVNIIKATEIFRDN-----------NTLYFVFEYMRQNLYELIKSRGSNLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGHEL---
|. | | ||.|  ... ..           |.||.||||| . |.....           .... .|......|.||..  |||||| |||         
LKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKC

--IKLADFGQAREIRS-------RPPYTDYVSTRWYRAPEVQLGSKNYN--SPIDIWAVACIMSEVYS---GRPLFPGSGTIDQVYKICGVLGTPTKATW
  .|.|||| ||.  .       . .||  | |.||||||. ||||.|.   |||.|.| ||..| .    ..|||||.  |||  ||. ..||||  .|
GRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNW

GEGVGLAVSMSIRLPIMVPTPLSALVPTASDDGISVMKEMLQWNPRRRPTAKQVLMHKYF
 . . |                              .  ||. .| .| .|.| | |.||
PGVTKLPDY-------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase AqueK132.AA CDC2 76-307 38 4.5e-72 220.65 In-house 54-301 (301) Show / Hide 
Range on Protein: 76-307
Range on HMM: 54-301/301
Sequence Identity: 38% (96 aa)

LQRLK-HVNIIKATEIFRDNNTLYFVFEYMRQNLYELIK-SRGS-NLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGHELIKLADFGQARE
|. || | ||.|  ...   | || ||||. ..| .. . | ..   .|...|... |||.|.|.. |... .|||||| |||      ||.|||| || 
LKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARA

IRS-RPPYT--DYVSTRWYRAPEVQLGSKNYNSPIDIWAVACIMSEV---YSGRPLFPGSGTIDQVYKICGVLGTPTKATWGEGVGLAVSMSIRLPIMVP
.     .||    | |.||||||. ||.| |. |.|.|.. ||..|     . .|||.|   ||| .||  .||||.  || .||          |   |
FGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTW-PGVTQLPDYKNTFPRWKP

TPLSALVPT---------ASDDGISVMKEMLQWNPRRRPTAKQVLMHKYF
. || ..|          . ..||.. ..||| .| .| .||. | |.||
QDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase AqueK132.AA ERK7 76-307 37 4.6e-67 228.35 In-house 52-292 (292) Show / Hide 
Range on Protein: 76-307
Range on HMM: 52-292/292
Sequence Identity: 37% (90 aa)

LQRLK-HVNIIKATEIFRDNNT--LYFVFEYMRQNLYELIKSRGSNLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGHELIKLADFGQARE
|| .. | |||.  ...| .|   .| |||.|   |   |.    |.  .  .. | ||...|. ||||  . |||||| |||     ..|..||| || 
LQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRK--GNILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARS

IRSRP-------PYTDYVSTRWYRAPEVQLGSKNYNSPIDIWAVACIMSEVYSGRPLFPGSGTIDQVYKICGVLGTPTKATWGE-GVGLAVSMSIRLPIM
| ...         |.|| ||||||||. |||..|   .| | . ||. |   |.|.|||. |..|. ||  ... ||..     |  .|..|  ...  
IAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQ

VPTPLSALVPTASDDGISVMKEMLQWNPRRRPTAKQVLMHKYF
 . .|....| ..||.|. .|..|. ||..| ||.| | | | 
KRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase AqueK132.AA MOK 72-307 38 6.8e-67 208.52 In-house 47-283 (283) Show / Hide 
Range on Protein: 72-307
Range on HMM: 47-283/283
Sequence Identity: 38% (92 aa)

DVHALQRLK-HVNIIKATEIFRDNNT--LYFVFEYMRQNLYELIKSRGSNLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGHELIKLADFG
.. |..||  | ||..  |.  |  |  |  . | |  |.||||. |   | |.. ...  ||.....  ||  |.|||| |||||| .  . .||||||
EIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYL-PQKKIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIK-QDHLKLADFG

QAREIRSRPPYTDYVSTRWYRAPEVQLGSKNYNSPIDIWAVACIMSEVYSGRPLFPGSGTIDQVYKICGVLGTPTKATWGEGVGLAVSMSIRLPIMVPTP
  | . |. |||.|.|||||||||  |    |   .|.|.| |.  |. | .|||||   .||. ||  |.||| . .       . .|.   |      
SCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPLFPGVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFPFKKGSG

LSALVPTASDDGISVMKEMLQWNPRRRPTAKQVLMHKYF
.  |.| ..   ...|..|  . |  | ||.||. | ||
IEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase AqueK132.AA MAPK 76-307 32 1.1e-66 227.85 In-house 58-328 (328) Show / Hide 
Range on Protein: 76-307
Range on HMM: 58-328/328
Sequence Identity: 32% (88 aa)

LQRL-KHVNIIKATEIFRDN-----------NTLYFVFEYMRQNLYELIKSRGSNLFPEHVVRNISYQIIQA--VSYMHSQGLFHRDLKPENILCQGHEL
|... .| ||||  .||.             |..|.|.|.|  .|. .|||.      .. .. . |||. .  . |.|| .  ||||||.|||.    .
LRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQ--PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCD

IKLADFGQAREIRSRPPY---------------TDYVSTRWYRAPEVQLG--SKNYNSPIDIWAVACIMSEVYS-GRPLFPGSGTIDQVYKICGVLGTPT
 |..||| || | .   .               |.||.||||||||. |.  ...|.  .|.|.| ||. | .. ..|||||. .|||  .|  |||||.
LKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPS

KATWGEGV--GLAVSMSIRL---PIMVPTPLSALVPT----ASDDGISVMKEMLQWNPRRRPTAKQVLMHKYF
.  .        | ..  .|   | . . |.. . |     |... |  .. ||...| .| |... | | ||
EEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase AqueK132.AA CDKL 76-241 44 2.8e-63 215.21 In-house 52-218 (286) Show / Hide 
Range on Protein: 76-241
Range on HMM: 52-218/286
Sequence Identity: 44% (76 aa)

LQRLKHVNIIKATEIFRDNNTLYFVFEYMRQNLYELIKSRGSNLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQ-GHELIKLADFGQAREIR
|  ||| ||    |.|| .. |. ||||.  .. .. .    |  .|||||.. .||..|... |..   ||| ||||||    .  .|| ||| || . 
LKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEE-YPNGVDEHVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-ML

SRPP--YTDYVSTRWYRAPEVQLGSKNYNSPIDIWAVACIMSEVYSGRPLFPGSGTIDQVYKICGVLGT
. |   ||||| ||||||||  .|   | .|.||||..|.| |  .| ||.||.. ||| |.|  .||.
AKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLWPGQSDIDQLYHIQKCLGP
Kinase AqueK132.AA CDK5 76-307 35 6.9e-62 194.14 In-house 52-287 (287) Show / Hide 
Range on Protein: 76-307
Range on HMM: 52-287/287
Sequence Identity: 35% (84 aa)

LQRLKHVNIIKATEIFRDNNTLYFVFEYMRQNLYELIKSRGSNLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGHELIKLADFGQARE--I
|. ||| ||.    .   .. |  |||.. | |   . |..      |... . ||  . ... |..   |||||| | |   .   |||||| ||   |
LKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNG-EMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGI

RSRPPYTDYVSTRWYRAPEVQLGSKNYNSPIDIWAVACIMSEVY-SGRPLFPGSGTIDQVYKICGVLGTPTKATWGEGVGLAVSM--SIRLPIMVPTP-L
  |  |.  | | |||.| | .||| |. .||.| . ||. |.  .|||||||... ||  .|  ..|||.  .|     |         .|.  ... .
PVR-CYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSW

SALVPTASDDGISVMKEMLQWNPRRRPTAKQVLMHKYF
. .||  .  |   ...||| ||  | .||. |.| ||
QQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase AqueK132.AA RCK 7-56 60 6.7e-28 85.37 In-house 1-50 (298) Show / Hide 
Range on Protein: 7-56
Range on HMM: 1-50/298
Sequence Identity: 60% (30 aa)

YTFLKVLGDGTFGVVSLAKEKETGNMVAIKKMKQDFLSWEECLKLKEVQV
|...| |||||.|.| .|. ||||. |||||||| | ||||| .|.|...
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKS
Kinase AqueK132.AA MAK 7-54 37 1.2e-20 62.04 In-house 1-78 (352) Show / Hide 
Range on Protein: 7-54
Range on HMM: 1-78/352
Sequence Identity: 37% (29 aa)

YTFLKVLGDGTFGVVSLAKE------------------------------KETGNMVAIKKMKQDFLSWEECLKLKEV
|...| |||||.| | |||.                              ..|| .||||.||. | |||||..| ||
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREV
Kinase AqueK132.AA CDC2 7-41 37 2.5e-12 33.69 In-house 1-35 (301) Show / Hide 
Range on Protein: 7-41
Range on HMM: 1-35/301
Sequence Identity: 37% (13 aa)

YTFLKVLGDGTFGVVSLAKEKETGNMVAIKKMKQD
|. .. .| ||.|||  .|...|. .||.|| . .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLE
Kinase AqueK132.AA TyrKc 7-307 19 4.6e-12 -27.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-307
Range on HMM: 1-280/280
Sequence Identity: 19% (68 aa)

YTFLKVLGDGTFGVVSLAKEKETGNMVAIKKMKQDFLSWEECLKLKEVQVSELFVSPYIYKYGRNDVHA----LQRL--KHVNIIKATEIFRDN------
 |..|.|| | ||.| ... |    .||.|..| |                            | | .     . .|  .| ||..   . ..       
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMY

-NTLYFVFEYMRQ-NLYELIKSRGSNLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGHELIKLADFGQAREIRSR-------PPYT-----
   |. |.|||   .| . ..... . ..     ....|| .  .| ||... ||||   |.|      .| .||| .|.| .          |.     
IEPLMIVMEYMPHGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHK

-DY--VSTRWYRAPEVQLGSKN-YNSPIDIWAVACIMSEVYS-GRPLFPGS----GTIDQVY---KICGVLGTPTK----ATWGEGVGLAVSMSIRLPIM
     .  ||. |||.    .. ...  |.|.    | |... | .  ||      . ..|.   |  . .  |      .                   
GGKTMLPIRWM-APECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------

VPTPLSALVPTASDDGISVMKEMLQWNPRRRPTAKQVLMHKYF
     .   ....|.  ..||.  . .|  ||| ...  |..|
-----F---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase AqueK132.AA CDK 7-37 44 9.6e-12 33.68 In-house 1-36 (284) Show / Hide 
Range on Protein: 7-37
Range on HMM: 1-36/284
Sequence Identity: 44% (16 aa)

YTFLKVLGDGTFGVVSLAKEKETG-----NMVAIKK
|  |. .| ||.|||  |. |.||     ..||.||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKK
Kinase AqueK132.AA CDKL 266-307 32 7.7e-10 29.82 In-house 244-286 (286) Show / Hide 
Range on Protein: 266-307
Range on HMM: 244-286/286
Sequence Identity: 32% (14 aa)

PTPLSALVPTAS-DDGISVMKEMLQWNPRRRPTAKQVLMHKYF
. ||   .|..|    .. || .|. .|..|.|..| . | ||
MEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase AqueK132.AA CDK5 7-41 40 3e-09 24.88 In-house 1-35 (287) Show / Hide 
Range on Protein: 7-41
Range on HMM: 1-35/287
Sequence Identity: 40% (14 aa)

YTFLKVLGDGTFGVVSLAKEKETGNMVAIKKMKQD
|  .  .|.||.|.|  |..|||. .||.|. . |
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLD
Kinase AqueK132.AA MAPK 7-38 42 7.5e-09 26.51 In-house 1-38 (328) Show / Hide 
Range on Protein: 7-38
Range on HMM: 1-38/328
Sequence Identity: 42% (16 aa)

YTFLKVLGDGTFGVVSLAKEKE------TGNMVAIKKM
|. || .| | .|||  |. |.      .|. |||||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKI
Kinase AqueK132.AA MOK 7-55 38 1.4e-07 19.32 In-house 1-49 (283) Show / Hide 
Range on Protein: 7-55
Range on HMM: 1-49/283
Sequence Identity: 38% (19 aa)

YTFLKVLGDGTFGVVSLAKEKETGNMVAIKKMKQDFLSWEECLKLKEVQ
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YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQ
Kinase AqueK132.AA Pkinase_Tyr 7-41 38 8.6e-07 23.63 Pfam 1-39 (270) Show / Hide 
Range on Protein: 7-41
Range on HMM: 1-39/270
Sequence Identity: 38% (15 aa)

YTFLKVLGDGTFGVVSLAKEK----ETGNMVAIKKMKQD
 ||.|.|| | ||.| ... |    .|.  ||.|..|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG
Kinase AqueK132.AA ERK7 7-38 43 9e-06 15.34 In-house 1-32 (292) Show / Hide 
Range on Protein: 7-38
Range on HMM: 1-32/292
Sequence Identity: 43% (14 aa)

YTFLKVLGDGTFGVVSLAKEKETGNMVAIKKM
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YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKI
Kinase AqueK132.AA CDKL 7-37 51 1.4e-05 15.04 In-house 1-31 (286) Show / Hide 
Range on Protein: 7-37
Range on HMM: 1-31/286
Sequence Identity: 51% (16 aa)

YTFLKVLGDGTFGVVSLAKEKETGNMVAIKK
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YEKLGKVGEGSYGVVMKCRNKETGQIVAIKK
Kinase AqueK132.AA Pkinase_Tyr 97-173 28 0.091578 6.6 Pfam 82-161 (270) Show / Hide 
Range on Protein: 97-173
Range on HMM: 82-161/270
Sequence Identity: 28% (23 aa)

LYFVFEYMRQ-NLYELIKSR--GSNLFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQGHELIKLADFGQAREI
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IYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI