Gene AqueK149 (A.queenslandica)

AqueK149

Species: A.queenslandica
Alias: AqueK149
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-a2

Sequence

Name Sequence Type Origin Length Description Download
AqueK149.AA Protein None 800 None Fasta, JSON
AqueK149.kin_dom Protein Kinase Domain None 105 None Fasta, JSON

Protein domain

Protein domains of AqueK149.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK149.AA TKL 671-745 21 1e-13 45.79 In-house 1-121 (364) Show / Hide 
Range on Protein: 671-745
Range on HMM: 1-121/364
Sequence Identity: 21% (26 aa)

LGSGGWGKVEVGLLHG----------QKVAVKMLHS--DIKSPY-----------------------YNQLVRREISMLAKVRHPNLLLFIAGVLDHPSG
.|||| |.|  | ..|          . ||||...|  | ..                         ...  ..|| |. . ||||...|.. ... |.|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

S-----------PIIITELLD
            . |..|. .
CVCMHPVGPWGQLCIVMEYCP
Pkinase_Tyr AqueK149.AA Pkinase_Tyr 665-743 23 3.8e-13 45.15 Pfam 1-88 (270) Show / Hide 
Range on Protein: 665-743
Range on HMM: 1-88/270
Sequence Identity: 23% (21 aa)

LTNKDTLGSGGWGKVEVGLLH------GQKVAVKMLHSDIKSPY-YNQLVRREISMLAKV-RHPNLLLFIAGVL--DHPSGSPIIITEL
.|   .||.|  |.|  | ..      ...||||||  .  ..  . .   ||.... .  .|||.. ... ..  . |. ...|..|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEY
Kinase AqueK149.AA MLK 665-745 26 1.3e-11 36.72 In-house 1-93 (291) Show / Hide 
Range on Protein: 665-745
Range on HMM: 1-93/291
Sequence Identity: 26% (25 aa)

LTNKDTLGSGGWGKVEVGLLHGQK-----VAVKMLHSDI--KSPYY--NQLVRREISMLAKVRHPN----LLLFIAGVLDHPSGSPIIITELLD
....  .|||. |||. |  ...      ||||. ...|  ||  |   . ...|.  |....|||       | .. |..|     |..| ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVMEYCE
Kinase AqueK149.AA AMPK 665-722 37 1.6e-11 30.52 In-house 1-61 (254) Show / Hide 
Range on Protein: 665-722
Range on HMM: 1-61/254
Sequence Identity: 37% (23 aa)

LTNKDTLGSGGWGKVEVGL--LHGQKVAVKMLHSD-IKSPYYNQLVRREISMLAKVRHPNL
   ..|.| |  ||| .|   | |.|||.| |  . ||.    . ..|||..| ..|||..
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHI
Kinase AqueK149.AA LISK 670-743 37 2.3e-11 33.0 In-house 1-78 (296) Show / Hide 
Range on Protein: 670-743
Range on HMM: 1-78/296
Sequence Identity: 37% (30 aa)

TLGSGGWGKVEVGLLH--GQKVAVKMLHS---DIKSPYYNQLVRREISMLAKVRHPNLLLFIAGVLDHPSGSPIIITEL
 .|.|. |||  | .   || .|.||.|.   | . | |   . ||. |. . |||| . |. ||. | .|.  |.||.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFM-GVCYHNDGQLHIVTEY
Kinase AqueK149.AA CAMKL 669-721 27 1.5e-10 29.7 In-house 5-76 (297) Show / Hide 
Range on Protein: 669-721
Range on HMM: 5-76/297
Sequence Identity: 27% (20 aa)

DTLGSGGWGKVEVGLLH---GQKVAVKMLHSDIKS--PYYNQL-----------VRREISMLAKVR---HPN
.||| |. |||  ..     |.|||.|... . ..  |. ..            .||||. . ...   |||
KTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPN
Kinase AqueK149.AA LISK-DD1 670-747 39 3.2e-10 33.41 In-house 1-83 (290) Show / Hide 
Range on Protein: 670-747
Range on HMM: 1-83/290
Sequence Identity: 39% (33 aa)

TLGSGGWGKVEVGLLHGQKVAVKMLHS---DIKSPYYNQLVRREISMLAK---VRHPNLLLFIAGVLDHPSGSPIIITELLDTS
  |.|. |||  | . |  ||.| .|.   | . | |  .. |||.||      ||||.  || |.  ||  || ..  ||. |
EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPNDPDYWKFMQREIKMLKNLLNIRHPNIVQFI-GICEHPLASPSLVNRLLNES
Kinase AqueK149.AA Dicty4 665-725 33 3.3e-09 27.05 In-house 1-63 (277) Show / Hide 
Range on Protein: 665-725
Range on HMM: 1-63/277
Sequence Identity: 33% (21 aa)

LTNKDTLGSGGWGKVEVGLLHGQKVAVKML--HSDIKSPYYNQLVRREISMLAKVRHPNLLLF
..  . .|.|. |.|  |   |..||||.|  | .  . .  .  |.|.. ..| ||||..||
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLF
Kinase AqueK149.AA CAMK 670-723 22 3.6e-09 24.95 In-house 1-101 (425) Show / Hide 
Range on Protein: 670-723
Range on HMM: 1-101/425
Sequence Identity: 22% (23 aa)

TLGSGGWGKVEVGLLH-G-------------QKVAVKMLHSD-IKS-------------------------PYYNQLVRREISMLAK-------VRHPNL
|||.|. |||  .                  ||||.|..  . .|.                         |.  . |||||... |       ..|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

L
.
I
Kinase AqueK149.AA Pkinase 665-748 22 4e-09 33.36 Pfam 1-91 (293) Show / Hide 
Range on Protein: 665-748
Range on HMM: 1-91/293
Sequence Identity: 22% (21 aa)

LTNKDTLGSGGWGKVEVGLLHGQK--VAVKMLHSDIKSPYYNQLVRR--EISMLAKVRHPNLLLFIAGVLDHPSGSPIIITELLDT-----SL
.. . ..|||. |.|  .  .|    |||| .  . ...  .|  ||  ||.......||| . ..  . |  .... ...|...      .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDL
Kinase AqueK149.AA NuaK 668-721 31 4.7e-09 19.39 In-house 4-60 (252) Show / Hide 
Range on Protein: 668-721
Range on HMM: 4-60/252
Sequence Identity: 31% (18 aa)

KDTLGSGGWGKVEVGLL--HGQKVAVKMLH-SDIKSPYYNQLVRREISMLAKVRHPN
. |||.| .|||. .     |..||.|    . |...     .|||| ..  . ||.
QKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPH
Kinase AqueK149.AA Csk 665-733 31 1.8e-08 25.07 In-house 1-67 (251) Show / Hide 
Range on Protein: 665-733
Range on HMM: 1-67/251
Sequence Identity: 31% (22 aa)

LTNKDTLGSGGWGKVEVGLLHGQKVAVKMLHSDIKSPYYNQLVRREISMLAKVRHPNLLLFIAGVLDHP
|.  .. | |  | | .| . ..|||||..  |  .    |    | |   . |||||  .|  .|...
LHLGECIGHGEFGDVMQGEYQNRKVAVKCIKCD--GNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQK
Kinase AqueK149.AA TyrKc 665-799 11 0.000274 -153.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 665-799
Range on HMM: 1-280/280
Sequence Identity: 11% (34 aa)

LTNKDTLGSGGWGKVEVGLLHGQKVAVKMLHSDIKSPYYNQLVRREISMLAKV--RHPNLLLFIAGVLDH-----PSGSPIIITEL-----LDTSLRKAY
.| ...||.|  |.|  | .  ..||||||..|       .  .||.... |.  .|||.. ... ....      .. . |..|.     |.  |||  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

TDRLIGSDRIFLLLDVC------------------------HSY------------LTHQ--------YDMT----NG---LP-----------------
 . |  .| .   ....                        . .            ...         | ..    .|   ||                 
PK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

--------------------------------RTVNKLGTG-------P---------------------------------ILLKL
                                . .... .|                                         |  ..
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK149.AA S_TKc 665-796 11 0.000566 -118.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 665-796
Range on HMM: 1-231/231
Sequence Identity: 11% (28 aa)

LTNKDTLGSGGWGKVEVGLLHG--QKVAVKMLHSDIKSPYYNQLVRREISMLAKVRHPNLLLFIAGVLDHPSGSPIIITELLDT---SLRKAYTDR----
 .  ...|.|. |||  .  ..  ..||.|...         . .||||..| | .|||.  ..    |   ..  ...|..|.   .|..   .|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LIGSDRIFLLLDVC------------------------------------------------------HSY---------------LTHQY-----
    .   .  |..  .|                                                      ...               |. .      
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFPQM

-------------DMTNGLPR-------TVNKLGT-------GPIL
             |. ... .       |. .. .        | .
QMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF