Gene AqueK141 (A.queenslandica)

AqueK141

Species: A.queenslandica
Alias: AqueK141
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-B

Sequence

Name Sequence Type Origin Length Description Download
AqueK141.AA Protein None 739 None Fasta, JSON
AqueK141.kin_dom Protein Kinase Domain None 242 None Fasta, JSON

Protein domain

Protein domains of AqueK141.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK141.AA Kelch_2 6-62 17 0.000143 21.49 Pfam 1-51 (51) Show / Hide 
Range on Protein: 6-62
Range on HMM: 1-51/51
Sequence Identity: 17% (10 aa)

KRSGHSTVRVGDYLYMWGGNQPDLPEVHNNEEKKSMCSVMEVCHLLTGRWEQKPTTG
 |..|... .|. .|..||         .. .. . .... .... | ||.  |  .
PRYCHASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK141.AA Kelch_1 6-62 17 0.789562 6.74 Pfam 1-45 (45) Show / Hide 
Range on Protein: 6-62
Range on HMM: 1-45/45
Sequence Identity: 17% (10 aa)

KRSGHSTVRVGDYLYMWGGNQPDLPEVHNNEEKKSMCSVMEVCHLLTGRWEQKPTTG
.|.||. . .....|  ||  .            .  .  |. .. |..|.. |. .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK141.AA Kelch_1 67-114 16 0.000297 19.02 Pfam 1-45 (45) Show / Hide 
Range on Protein: 67-114
Range on HMM: 1-45/45
Sequence Identity: 16% (8 aa)

GVSGYAAAAIGRVIFYFAGWCNYVGCLHNSLYSFNVDTFNWKELSPTT
  .|....... .|. . |...      || ......|  |....| .
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK141.AA Kelch_2 67-114 15 12.106624 2.77 Pfam 1-51 (51) Show / Hide 
Range on Protein: 67-114
Range on HMM: 1-51/51
Sequence Identity: 15% (8 aa)

GVSGYAAAAIGRVIFYFAGW---CNYVGCLHNSLYSFNVDTFNWKELSPTT
. .. |.. .|  |. | |.       .| ..... .. .|  |.....  
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_2 AqueK141.AA Kelch_2 244-289 21 0.048482 11.88 Pfam 1-51 (51) Show / Hide 
Range on Protein: 244-289
Range on HMM: 1-51/51
Sequence Identity: 21% (12 aa)

ERRAHSSVLINTNSGPHLLVVGGV---------RSHGLWIFDIKNKSWKELFNTP
 |  |.|. .    |  ..|.||.         .|  .|..| . ..|...   |
PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK141.AA Kelch_1 258-289 17 2.220318 5.13 Pfam 11-45 (45) Show / Hide 
Range on Protein: 258-289
Range on HMM: 11-45/45
Sequence Identity: 17% (6 aa)

GPHLLVVGGVR---SHGLWIFDIKNKSWKELFNTP
. .. |.||.    .   ...| ....|... . |
NGKIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK141.AA Kelch_2 294-340 27 24.145723 1.63 Pfam 1-32 (51) Show / Hide 
Range on Protein: 294-340
Range on HMM: 1-32/51
Sequence Identity: 27% (13 aa)

NRYSHSLSLWSVTPTTNWIIVFGGEMSYTDTAVIELRYTSNNDWSTS
.||.|. . .      ..|.||||            |.| |||....
PRYCHASCVP-----GGKIYVFGGYC----------RHTHNNDCWSM
Kinase AqueK141.AA TKL 501-735 19 1.6e-46 160.89 In-house 1-364 (364) Show / Hide 
Range on Protein: 501-735
Range on HMM: 1-364/364
Sequence Identity: 19% (72 aa)

LGRGGWGEVRVARFHG----------LEVAAKVLHETIISEYNV-------------------------SLFSREMNIASKLRHPNLLQFIGATTEGN--
.|.|| |||  ....|           .|| |.....  .| .                            . .|... |.|||||..||.|. ....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PIILTELM-PTSLRKELETGGLAYHAVLNISLDVACALNYLHLFKP-----HPILHRDVSSANVLLQPMGGVH--------GGLRAKV
            . | .|..   ||.  |       |  ....||.|...||||  .|      ||.|||  |.|.|.   . ..           ..|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

SDYGSANLQHLI---------------------IRSVNPGGPLYAAPEAANPR----------------EHSPSMDVFSYGVLLLEMITRRIPLPEER--
.|.| .   .                        ..   | | . |||. .                  | |...||.|.|..| |..||..|  ..   
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------VGLIDGIRR--------------------ASFRSLVQRCLIVEYRHRPTMNDIITEL
            .. .|  .|                     |...| |.|   . . ||....|. .|
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK141.AA S_TKc 495-739 20 8.4e-30 106.24 SMART 1-231 (231) Show / Hide 
Range on Protein: 495-739
Range on HMM: 1-231/231
Sequence Identity: 20% (55 aa)

RMTERILGRGGWGEVRVARFHG--LEVAAKVLHETIISEYNVSLFSREMNIASKLRHPNLLQFIGATTEGNPIILTELMPT---SLRKELETGG------
    |..|.|. |.|. .| ..   .|| |...           . ||..| .| .|||. .....  ...  . .|....   .|.. ..  |      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LAYHAVLNISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGVHGGLRAKVSDYGSANLQHLIIRSVNPGGPLYAAPEAANPREHSP-SMDVFSYG
 .    .  .   ..|||.|.|  .   |.|||.  .|.||          . |..| |.| .      .   | | | |||      ... . |. | |
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLLEMITRRIPLPEERVGLIDGIRRASFRSLVQRCLIVEYRHRPTMNDIIT-----ELNDTI
..| ||.... | | .   ... |.  ........|| .. ..|||  .. .      .   .
CILYEMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK141.AA MLK 495-693 24 1.5e-27 92.72 In-house 1-235 (291) Show / Hide 
Range on Protein: 495-693
Range on HMM: 1-235/291
Sequence Identity: 24% (59 aa)

RMTERILGRGGWGEVRVARFHGLE-----VAAKVLHETIISEYNVS-----LFSREMNIASKLRHPN----LLQFIGATTE-GN-PIILTELMPT-SLRK
  .....| |. |.|  .|... .     || |  . .|. .  ..      | .| .....|.|||      || |. .. ..   |..| ..  ||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELETG---------------GLAYHAVLNISLDVACALNYLHLFKPHPILHRDVSSANVLLQP-MGGVHGGLRAKVSDYGSANLQHLI-I-RSVNPGGPL
 | ..                   . ..|..|..| ...|||  .|.|| |||  | |.|.    .   ... .|..| | .   | .   .  |.| . 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

YAAPEA---ANPREHSPSMDVFSYGVLLLEMITRRIP
. |||.   .     | . ||.|.||.| ||.||..|
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK141.AA TK 498-735 14 1.8e-26 85.13 In-house 4-486 (486) Show / Hide 
Range on Protein: 498-735
Range on HMM: 4-486/486
Sequence Identity: 14% (68 aa)

ERILGRGG---WGEVRVARFHGL---------------------------EVAAKVLHETIISEYN-VSL--------------FSREMNIAS--KLRHP
.. ||.|    .|||. .. .|.                           .|| |.|.|.  .. .   .              . .|| . .  ...||
GKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHP

NLLQFIGATTEGN-------------PIILTELMP-TS----LRKELETGG-------------------------------------------------
|.....|. |.|              ..|..|.||  .    ||. | .                                                   
NIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDD

----------------------------LAYHAVLNISLDVACALNYLHLFKPHPI----LHRDVSSANVLLQPMGGVHG-----GLRAKVSDYGSAN--
                            |  |  | .....||.. |||  .         |||.   |.|.   . ...     |. .|..|.| .   
LIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQG

---LQHLI------IRSVNPGGPL-------------------------YAAPEAAN---------PREHSPSMDVFSYGVLLLEMIT--RRIPLP----
   |   |       |. ..|...                         . |||. |          . ...  ||.|.|||. |. |  .  . .    
SGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSN

------------------------------EERVGLI--DGIRR-------------ASFRSLVQRCLIVEYRHRPTMNDIITEL
                              ..|  .   ..                . .  | |.|   . ..|||. ..  .|
QDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK141.AA Pkinase 495-739 18 4e-25 89.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 495-739
Range on HMM: 1-293/293
Sequence Identity: 18% (56 aa)

RMTERILGRGGWGEVRVARFHGLE--VAAKVLH-ETIISEYNVSLFS-REMNIASKLRHPNLLQFIGAT-TEGNPIILTELMPT-----SLRKELE---T
  ..|..|.|. |.|. .. .| .  || |..  ... |. .....  .|  |  .|.||| ......  ..... . .|...      .|   ..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GGL--AYHAVLNISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGVHGGLRAKVSDYGSAN---LQHLIIRSVNPGGPLYAAPEAAN-PREHSPSM
|..   .. . .. . ....|.|.|      |.|||. ..|.|.   | .    . |..| |.|    . .    ..  | | |.|||  .  ....|. 
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVFSYGVLLLEMITRRIPLPEE-------RVGLIDGIRR-------------------------------ASFRSLVQRCLIVEYRHRPTMNDIITELND
|..|.|..| ||...| | |..          .|. |..                                ...... .|| .    |||    ....  
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQ

T--I
   .
HPWF
Kinase AqueK141.AA CZAK 498-623 39 1.3e-24 86.4 In-house 4-142 (279) Show / Hide 
Range on Protein: 498-623
Range on HMM: 4-142/279
Sequence Identity: 39% (55 aa)

ERILGRGGWGEVRVARFHGLEVAAKVLHETIISEYNV----SLFSREMNIASKLRHPNLLQFIGATTEGN---PIILTELMP-TSLRKELETGGLAYHAV
..  |.|  |||. |.  |  || | .|     .         | .|  | |||.||| .||.|| .|..     | .| |   |||. | |    ||  
GQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLL-TDHYFYHKQ

-----LNISLDVACALNYLHL-FKPHPILHRDVSSANVLL
     .|. .|.|   ||||  .|| |||||| || |.||
NPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILL
Kinase AqueK141.AA TKL-Unique 497-693 25 2.5e-21 72.07 In-house 1-233 (290) Show / Hide 
Range on Protein: 497-693
Range on HMM: 1-233/290
Sequence Identity: 25% (62 aa)

TERILGRGGWGEVRVARFHGLEVAAKVLH-ETIISEYNVSLFSREMNIASKLR-HPNLLQFIGATT-----EGNPIILTELMPT-SLRKELE--------
    .|.|| |.|  . ..| .|| |..| .  .|   .  |..| |. .||. |||.....|...     ..| .| .| .|  ||.. |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

---TGGLAYHAVLNISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGVHGG-----LRAKVSDYGSANLQHLIIRSVNP-----------GGPLYA
      | .  .... .|.| ...|||  .|  |.|||  | |.|      |  .     ...|..| | . ..  |... |            | ....
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFL------VDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWM

APEAANP--REHSPSMDVFSYGVLLLEMITRRI------P
|||  .      | . ||.|.|. | |..|| |      |
APEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase AqueK141.AA STE 496-730 16 1.6e-20 69.25 In-house 1-350 (359) Show / Hide 
Range on Protein: 496-730
Range on HMM: 1-350/359
Sequence Identity: 16% (60 aa)

MTE-RILGRGGWGEVRVARFH-----------------GLEVAAKVLH----ETIISE------------YNVSLFSREMNIASKLR--HPNLLQFIGAT
 .  ...|.|. |.|  |. |                 |  .| |...    .. . |             ..  . .|..| .|..  |||  ...|. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

T--------EGNPIILTELMP-TSLRKELE-TGGLA--------------YHAVLNISLDVACA-LNYLHLFKPHPILHRDVSSANVLLQPMGGVHGGLR
         ...  |  |.|.  ||.. .. ..|                 . .  |  ..  . |.|||  .   | |||. .||.||           
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----------

AKVSDYGSAN-LQHLII-----------------RSVNPGGPLYAAPEAANP------REHSPSMDVFSYGVLLLEMITRRIPL---PEERVGLIDGIRR
.| .| | .  |.. .                  |    | | . |||  ..       ... . |. | | ...||.| . |.   .  |. .   .  
VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNY

-------------------------------------------ASFRSLVQRCLIVEYRHRPTMND
                                            .|.  ...||. ....||| ..
HMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase AqueK141.AA LRRK 495-693 21 1.6e-19 65.69 In-house 1-282 (351) Show / Hide 
Range on Protein: 495-693
Range on HMM: 1-282/351
Sequence Identity: 21% (62 aa)

RMTERILGRGGWG-EVRVARFHG----------------------------LEVAAKVLHET-------------------------------IISEYNV
 . |. .|||| | .|  |.. |                             .||.|... .                               ...  ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-SLFSREMNIASKLRHPNLLQFIGATTEGNPIIL-TELMPT-SLRKELE---TGG-------LAYHAVLNISLDVACALNYLHLFKPHPILHRDVSSANV
 ..| .|. | |.|.|||... .| .   .|... .|..|  .| . |.     |       .  . .| |.|..| ...||| ..| ||.|||  | |.
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNI

LLQPM------GGVHGGLRAKVSDYGSAN----LQH-LIIRSVNPGGPLYAAPEAANPR---EHSPSMDVFSYGVLLLEMITRR-IP
||. .      . .     ||..|.|       ... .. ..| .  |.. |||  .     | .   |..|.|..| | .||. .|
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGN--PGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase AqueK141.AA Dicty4 497-572 38 3.6e-16 50.58 In-house 3-85 (277) Show / Hide 
Range on Protein: 497-572
Range on HMM: 3-85/277
Sequence Identity: 38% (32 aa)

TERILGRGGWGEVRVARFHGLEVAAKVL--HETIISEYNVSLFSREMNIASKLRHPNLLQFIGATT-----EGNPIILTELMP
.| ..|.|. |||  ..  | ||| |.|  | .  .|.  . | .| .| .|.||||...| || |      | . | ||.||
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMP
Kinase AqueK141.AA DRK 494-622 36 1.5e-15 49.18 In-house 1-132 (258) Show / Hide 
Range on Protein: 494-622
Range on HMM: 1-132/258
Sequence Identity: 36% (49 aa)

IRMTERILGRGGWGEVRVARFHGLEVAAKVLHETIIS-EYNVSLFSREMNIASKLRHPNLLQFIGATTE-GNPIILTELMPT-SLRKEL--ETGGLAYHA
|    || |||..|||      | .|| | |    |  |  .. | || |. ..|||||  ||.|. ..   . | .| ||  || . |  |   .    
IKIGNRI-GRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPL

VLNISLDVACALNYLHLFKPHPILHRDVSSANVL
.. . .|.|  ..|||   |  |.|||  | | |
MKQMMFDCAKGMIYLHCCNPI-IIHRDLKSHNLL
Pkinase_Tyr AqueK141.AA Pkinase_Tyr 494-641 25 2e-15 52.88 Pfam 1-156 (270) Show / Hide 
Range on Protein: 494-641
Range on HMM: 1-156/270
Sequence Identity: 25% (42 aa)

IRMTERILGRGGWGEVRVARFH------GLEVAAKVLHETIISEY--NVSLFSREMNIASKL-RHPNLLQFIGATT-EGNP---IILTELMPT-SLRKEL
|..  . ||.|  |||. .. .      ...|| |.| |.  .|     .... |..| ..| .|||.....|. | .| |   .| .|.||  .|.. |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

ETG-----GLAYHAVLNISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGVHGGLRAKVSDYG
 .       |  .  |......|....||.  .   . |||.   |.|.        .. .|..| |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE------NNVVKICDFG
Kinase AqueK141.AA TyrKc 495-735 22 6.1e-15 18.83 SMART 1-280 (280) Show / Hide 
Range on Protein: 495-735
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

RMTERILGRGGWGEVRVARFHGLEVAAKVLHETIISEYNVSLFSREMNIASKL--RHPNLLQFIGATTE--------GNPIILTELMPT-SLRKELETGG
   ...||.|  |||. ..   ..|| |.|.|       .  | ||..| .||  .|||.....|. |.        . . |..|.||  .|.. |   .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LAYHAVLNISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGVHGGLRAKVSDYG-SANLQHL--------IIRS----VNPG-GPL-YAAPEAA
  |     |......||  .|||    ... |||    |.|.   .      ..|.|| | | .. .          .|.       .  |.   |||. 
PKLCMKDLLSFCWQIACGMEYLHS---KNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

NPREHSPSMDVFSYGVLLLEMITRRIPLPEE-----------RVGLIDGIRRASFRS---------------LVQRCLIVEYRHRPTMNDIITEL
| .. ..  ||.|.||.. |. |.  . ...           .  . .| |.    .               . ..|   .   |||...|. ..
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK141.AA LISK 500-558 28 1.2e-12 37.2 In-house 1-64 (296) Show / Hide 
Range on Protein: 500-558
Range on HMM: 1-64/296
Sequence Identity: 28% (18 aa)

ILGRGGWGEVRVARFH--GLEVAAKVLH---ETIISEYNVSLFSREMNIASKLRHPNLLQFIGA
..|.|. |.|   .    | ..| | .|   .. . . .   . ||. .  .||||| .||.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV
Kinase AqueK141.AA Dicty4 676-737 24 9.8e-08 22.06 In-house 199-277 (277) Show / Hide 
Range on Protein: 676-737
Range on HMM: 199-277/277
Sequence Identity: 24% (19 aa)

DVFSYGVLLLEMITRRIPLP---EERVGLIDGIRR------------ASFRSLVQRCLIVEYRHRPTMNDIITE--LND
||.|.| .| |. || .| .    . . ..... .            .|...|.|.|.  .  |||... || .  |. 
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK141.AA LISK 674-695 54 2e-07 20.0 In-house 219-240 (296) Show / Hide 
Range on Protein: 674-695
Range on HMM: 219-240/296
Sequence Identity: 54% (12 aa)

SMDVFSYGVLLLEMITRRIPLP
| ||||.|..|.|.|||. . |
SCDVFSFGIVLCEIITRVKADP
Kinase AqueK141.AA LISK 590-623 44 0.000191 10.13 In-house 104-134 (296) Show / Hide 
Range on Protein: 590-623
Range on HMM: 104-134/296
Sequence Identity: 44% (15 aa)

LNISLDVACALNYLHLFKPHPILHRDVSSANVLL
..|.||.||.. |||  .   |.|||  | |.|.
VKIALDIACGMSYLHSMN---IIHRDLKSKNCLV
Kinase AqueK141.AA DRK 676-693 44 0.000501 9.57 In-house 184-201 (258) Show / Hide 
Range on Protein: 676-693
Range on HMM: 184-201/258
Sequence Identity: 44% (8 aa)

DVFSYGVLLLEMITRRIP
||.|... | |..|| .|
DVYSFAIVLWECVTRQDP
Kinase AqueK141.AA CZAK 660-693 32 0.014869 5.28 In-house 188-221 (279) Show / Hide 
Range on Protein: 660-693
Range on HMM: 188-221/279
Sequence Identity: 32% (11 aa)

YAAPEAANPREHSPSMDVFSYGVLLLEMITRRIP
. |||       ..  ||.|.| .| ..|| . |
WMAPECFKGENYTEKVDVYSFGMILWCIITCDQP
Kinase AqueK141.AA TKL-Unique 709-735 33 0.015089 5.02 In-house 264-290 (290) Show / Hide 
Range on Protein: 709-735
Range on HMM: 264-290/290
Sequence Identity: 33% (9 aa)

SFRSLVQRCLIVEYRHRPTMNDIITEL
..| | |.|   .   ||. ..||..|
EYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK141.AA DRK 708-737 23 0.019717 4.09 In-house 229-258 (258) Show / Hide 
Range on Protein: 708-737
Range on HMM: 229-258/258
Sequence Identity: 23% (7 aa)

ASFRSLVQRCLIVEYRHRPTMNDIITELND
. .  | ..|.  .  |||.| ...  |  
PKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK141.AA MLK 708-735 21 0.132088 1.5 In-house 264-291 (291) Show / Hide 
Range on Protein: 708-735
Range on HMM: 264-291/291
Sequence Identity: 21% (6 aa)

ASFRSLVQRCLIVEYRHRPTMNDIITEL
... .| ..|   . . ||..  |...|
EHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK141.AA LRRK 725-737 30 0.200746 0.78 In-house 339-351 (351) Show / Hide 
Range on Protein: 725-737
Range on HMM: 339-351/351
Sequence Identity: 30% (4 aa)

RPTMNDIITELND
||....|.  | .
RPHFSQIVKRLSQ
Kinase AqueK141.AA Pkinase_Tyr 676-690 53 0.602102 3.83 Pfam 196-210 (270) Show / Hide 
Range on Protein: 676-690
Range on HMM: 196-210/270
Sequence Identity: 53% (8 aa)

DVFSYGVLLLEMITR
|| |.|||. |..|.
DVWSFGVLMWEIFTY
Kinase AqueK141.AA Pkinase_Tyr 724-735 41 3.408398 1.28 Pfam 259-270 (270) Show / Hide 
Range on Protein: 724-735
Range on HMM: 259-270/270
Sequence Identity: 41% (5 aa)

HRPTMNDIITEL
.|||. .|. .|
DRPTFSEIHEQL