Gene AqueK215 (A.queenslandica)

AqueK215

Species: A.queenslandica
Alias: AqueK215
External Links:
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
AqueK215.AA Protein None 948 None Fasta, JSON
AqueK215.kin_dom Protein Kinase Domain None 292 None Fasta, JSON

Protein domain

Protein domains of AqueK215.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc AqueK215.AA S_TKc 20-319 23 4.7e-64 220.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-319
Range on HMM: 1-231/231
Sequence Identity: 23% (74 aa)

WDLKSLLGKGSYGNVYKGWNSQKTAEVAVKVVRKDLFRQDPKAEQNLMREIDVLKKLRQCEYVVHLYHVQDMQRADAIVMVMELCEC---DLDHLIKVKP
...  ..|||..| |||...     .||.|...           ....|||..|||  .....|.|| | .    | . ||||.|.    || ..|| ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRG

-------FCDQDVTVLLHQLGEGMKALRAHNIVHRDIKPGNILIKYHPKTGKMMIKLADFGFARHFKDESMKPLDLTSLAGTPVFMAPEALRCVFNPGVE
       |   ..  ...|. .... .  |.|.|||.|| |||.          ||..|||.||..          |.. ||| .|||| |         
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL----------TTFCGTPWYMAPEVL---------

HYDD-KVDLWSIGALIYKVLVGQCGFYAQLNHILHILDKKGDAIAWEPSTAPNYGPVPKVKYIYELPASLDERLSAPFKQKMNQLLVSLLKLDALERMTY
.|.  |.| ||.| ..|  |.|.  |. |.. .....                                          . . ...  .|. |  .|.| 
GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------------------------------------SPEAKDFIRKCLQKDPEKRPTA

PEFFD-----FVDDLL
 | .        .  .
-EALQDEWDIKCHPWF
Kinase AqueK215.AA ULK 20-313 25 3.5e-58 199.63 In-house 1-320 (324) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-320/324
Sequence Identity: 25% (89 aa)

WDLKSLLGKGSYG-NVYKGWNSQKT---AEVAVKVVRKDLFRQDPKA------EQNLMREIDVLKKLR--QCEY--VVHLYHVQDMQRADAIVMVMELCE
. |.  |||||.|  |||| | ..      ||.|.. |. ......        |.|..|| ..|||   ....  .| ||...  .  . | ..||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

C-DLDHLIKVK---PFCDQD---------VTVLLHQLGEGMKALRAHNIVHRDIKPGNILIKYH-PK-------TGKMMIKLADFGFARHFKDESMKPLD
. ||...|| .   |.             .   ..|. .|.|.|. |||.|||||| ||||. . ||         .  .|.||||||.|. ...|   .
GGDLEQYIKKNKKLPE-T-EEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNMEQQM

LTSLA------GTPVFMAPEALR----CVFNPGVEHYDDK-VDLWSIGALIYKVLVGQCGFYAQ-LNHIL---HILDKKGDAIAWEPSTAPNYGPVPKVK
....       ||| .|||. |     .      ..|.|. .|.||.| ..|  | |.. |...  . .|     ....  .          .       
CQTCVNEKRIKGTPLYMAPQILQGQGEQ------KPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNG-KE----------Q-------

YIYELPASLDERLSA---PFKQKMNQLLVSLLKLDALERMTYPEFFD
 ||.    .. ..     .. ... .|.  .|. |  .|.. .|.|.
QIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFN
Kinase AqueK215.AA ULK 20-313 26 1e-57 198.05 In-house 1-325 (329) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-325/329
Sequence Identity: 26% (93 aa)

WDLKSLLGKGSYGNVYKGWNSQKT----AEVAVKVVRKDLFRQDPKA------EQNLMREIDVLKKLR-------QCEYVVHLYHVQDMQRADAIVMVME
. |.  |||||.| |||| | ..       ||.|.. |. ..|...        | |..||...|||        .....| ||...  .  . | ..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCEC-DLDHLIKVK---PFCDQD---------VTVLLHQLGEGMKALRAHNIVHRDIKPGNILIKYH-PK-------TGKMMIKLADFGFARHFKDESMK
.|.  ||...|| .   | .            .   ..|. .|.|.|. |||.|||||| ||||. . ||         .. .|.||||||.|. ...| 
YCNGGDLEQYIKKNKKLPEDT-EEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDNME

PLDLTSLA------GTPVFMAPEALR----CVFNPGVEHYDDK-VDLWSIGALIYKVLVGQCGFYAQLNHILH---ILDKKGDAIAWEPSTAPNYGPVPK
  ....        ||| .|||. |     .      ..|.|. .|.||.| ..|  |.|.. |||. .  .    | . . .   |..           
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQ------KPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQ-----------

VKYIYELPASLDER-LSAPFKQKMNQLLVSLLKLDALERMTYPEFFD
   |   |   .    . .. ... .|.  .|. |  .|.. .|.|.
--QIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFN
Kinase AqueK215.AA CAMK 25-230 20 7.4e-55 174.83 In-house 1-330 (425) Show / Hide 
Range on Protein: 25-230
Range on HMM: 1-330/425
Sequence Identity: 20% (69 aa)

LLGKGSYGNVYKGWNSQKT------------AEVAVKVVRKDLFRQD------------------------PKAEQNLMREIDVLKKLR------QCEYV
 ||.||.| |... . . |             .||.|.. |.  . .                        || ..|..|||...|||.      . . .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VHLYHVQDMQR-----------------ADAIVMVM---ELCECD------LDHLIKVKP---------------FCDQDVTVLLHQLGEGMKALRAHNI
..||.| .  .                  . ..|||   |.|.        .|.... ..               |. ...  . .|. .... .  |||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKPGNILIKYHPKTGK------------MMIKLADFGFARHFKDESMKPLD--------------------LTSLAGTPVFMA-PEAL----RCVF
||||.|| |||. .. .                 ||..|||||..|.. .    .                    ..   ||| .|| || |    .|..
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

NPG-----VEHYDDKVDLWSIGALIYKVLVG
  .      . |. |.| ||.| . |  |.|
Q-NATDEEKPYYGPKCDMWSCGVILYIMLCG
Kinase AqueK215.AA Pkinase 20-231 31 2.3e-48 171.79 Pfam 1-209 (293) Show / Hide 
Range on Protein: 20-231
Range on HMM: 1-209/293
Sequence Identity: 31% (71 aa)

WDLKSLLGKGSYGNVYKGWNSQKTAEVAVKVVRKDLFRQDPKAEQNLMR--EIDVLKKLRQCEYVVHLYHVQDMQRADAIVMVMELCEC-----DLDHLI
. ... .|.||.| |||. .     .||||...|.  ..... .|.. |  || ..|.| .....| ||..      | | ||||.||.     || ..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYI

K---VKPF--CDQDVTVLLHQLGEGMKALRAHNIVHRDIKPGNILIKYHPKTGKMMIKLADFGFARHFKDESMKPLDLTSLAGTPVFMAPEALRCVFNPG
.    ..|   ....   . |. .|.. . ...|.|||.|| ||||. .. ..  ..|..|||.|..|.    .   .|...||| .|||| .|     |
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIR-----G

VEHYDDKVDLWSIGALIYKVLVGQ
 ..|. ||| ||.| ..| .| |.
GQYYGPKVDMWSCGCILYEMLCGR
Kinase AqueK215.AA AGC 20-237 19 9.2e-40 99.26 In-house 1-308 (395) Show / Hide 
Range on Protein: 20-237
Range on HMM: 1-308/395
Sequence Identity: 19% (62 aa)

WDLKSLLGKGSYGNVYKGWNSQ-----KT-AEVAVKVVRKDL-FRQDPK-AEQNLMRE------------IDVLKKLRQ---------CEYVVH-LYHVQ
 ... ..||||.| ||            |    |.||..|.    .. |  ... |.|             ..|.|...         . ..|. |..  
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

DMQRADAIVMVMELCE-----------CDLDHLI----KVKPFCDQDVTVLLHQ---LGEG-----MKALRA-HNIVHRD-IKPGNILIKYHPKTGKMMI
  .. . . .|||...           |.| . .    | . |  . .   . .   .  |     .  |   ..|.||| .|| |||.  .       |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKI-CGCIVLALEYLHSHMGIIHRDYLKPENILLDED-----GHI

KLADFGFARHFKDES---------------------------------MKPLD--------------LTSLAG--TPVFMAPEALRCVFNPGVEHYDDKV
||.|||..  ....                                  ..                  ... |  || .|||| |          |.  .
KLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----------YGKAC

DLWS--IGALIYKVLVGQCGFYAQ
| ||   |.|.|  |.|.  ||..
DWWSFGLGCLMYEMLTGYPPFYGD
Kinase AqueK215.AA STE 20-224 22 7.4e-38 131.28 In-house 1-258 (359) Show / Hide 
Range on Protein: 20-224
Range on HMM: 1-258/359
Sequence Identity: 22% (61 aa)

WDLKSLLGKGSYGNVYKGWNS------QKTAE---------VAVKVVRKDLFRQ-------------DPKAEQNLMREIDVLKKLRQ-CEYVVHLYHV-Q
|.. . .|||..| |||. |       ..  .         .|.|.....  ..             ... .|....||...||... ....|. |    
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DM---QRA-DAIVMVMELCEC-DLDHLIK-V--------------KPFCDQDVTVLLHQLGEG-MKALRAHNIVHRDIKPGNILIKYHPKTGKMMIKLAD
.    . . | . ..||...   || .|| .              ..|  . . . ..|. .| .. |  |.|.||||||.|||.          .||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCD

FGFARHFKDESMKP-------------LDLTSLAGTPVFMAPEALRC-VFNPGVEHYDDKVDLWSIGALI
||..  . |.. .                 ....||| .|||| ...   .  . .|| |.| ||.| .|
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTI
Kinase AqueK215.AA CAMKL 20-231 27 7e-36 111.88 In-house 1-233 (297) Show / Hide 
Range on Protein: 20-231
Range on HMM: 1-233/297
Sequence Identity: 27% (67 aa)

WDLKSLLGKGSYGNVYKGWNSQKT-AEVAVKVVRKDLFRQDPKAEQN-----------LMREIDVLKKLR--QCEYVVHLYHVQDMQRA----DAIVMVM
...   |||||.| |  ... . |  .||.|.. |.  . ||....|           . |||  .|.|.  . . ...||.| . ..     . |..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCECD----LDHLIKV----KPFCDQDVTVLLHQLGEGMKALRAHNIVHRDIKPGNILIKYHPKTGKMMIKLADFGFARHFKD-----ESMKPLDLTSL
|.|.      .|...|     ...   .   .  |. .... .  |.|||||||| |||. .. .     ||..||||. ....     . .    |.  
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPCIFGPGQK----LKTF

AGTPVFMAPEALRCVFNPGVEHYD-DKVDLWSIGALIYKVLVGQ
 |.| .||||    .|. . ..||  ||| ||.| . |  ..|.
CGSPPYMAPE----IFQGNNKPYDGPKVDIWSCGVILYAMVCGY
Kinase AqueK215.AA CMGC 20-175 19 2.1e-33 106.4 In-house 1-254 (513) Show / Hide 
Range on Protein: 20-175
Range on HMM: 1-254/513
Sequence Identity: 19% (50 aa)

WDLKSLLGKGSYGNVYKGWN-------------SQKTAE-VAVKVVRKDLFRQDPK-------AEQNLMREIDVLKKLR----------------QCEYV
 .  . .|.|.||.|||...               .| | ||.| .... .  . |         .   |||  ||.|.                . ...
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VHLYHVQDMQRAD---------------AIVMVMELCECDLDHLIKV----------KPFCDQD------------VTVLL------HQLGEGMK--ALR
|.|| .      |                . .|.|....|| ..||           .|. .              .  ..      .|. .|.|   . 
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

AHN--IVHRDIKPGNILIKYHPKT---------------GKMMIKLADFGFARHF
 |.  |.|||.|| ||||    .                 .. .|..|||.||..
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWY
Kinase AqueK215.AA Ciliate-E2 20-231 21 3.8e-33 111.12 In-house 1-293 (365) Show / Hide 
Range on Protein: 20-231
Range on HMM: 1-293/365
Sequence Identity: 21% (66 aa)

WDLKSLLGKGSYGNVYKG--WNSQK-------------------TA--EVAVKVVRKDLFRQDPKAEQNLMREID---------VLKKLRQCEYVVHLYH
 ..  ..|.|..| |||.  |. ||                   ..  ..|.|...|.  .|  | |...||||.          .... .. ... .| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQI-KQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VQDMQRADAIVMVMELCEC-DLDHLIKVKPFC------------DQDVTVLLHQLGE---------------GMKALRAHN-IVHRDIKPGNILIKYHPK
.  ..  . | .|||.|.  || ..|| .. .            .. .  .  |. .               ... |   | |.|||||| |||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

TGKMMIKLADFGFARHFKDE-----------SMKPLD------------------LTSLAGTPVFMAPEALRCVF---NPGVEHYDDKVDLWSIGALIYK
     ||..|||... ..|.            ..                       ...||| .|||| |.      . . ..|| |.|.||.| ..| 
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

VLVGQ
 | |.
MLFGK
Kinase AqueK215.AA TKL 26-225 20 2.6e-27 95.41 In-house 1-280 (364) Show / Hide 
Range on Protein: 26-225
Range on HMM: 1-280/364
Sequence Identity: 20% (59 aa)

LGKGSYGNVYKG-WNSQK-------TAEVAVKVVRK---DLFRQ-----------------DPKAEQNLMREIDVLKKLRQ--CEYVVHLYHVQDMQRAD
.|.|..| |||| |. .          .||||. ..   |.|                   ||.|...  .|. ... ...  .. .|... .    . .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

A-----------IVMVMELCEC-D-LDHLIKVKPFCDQDVTVL-LHQLGEGMKALRAHN--------IVHRDIKPGNILIK--YHPKTGKMM--------
            . .|||.|.. . |..|.        ....   ..   ||  | ..|        |.|||.|. |||..  ... .  .|        
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS-NYMYNPNADWC

IKLADFGFAR-HFKDESMKPLD---------------LTSLAGTPVFMAPEALRCV--FNPGV--------EHYDDKVDLWSIGALIY
.|..|||..| ......|.                  . .  ||| .||||.||    ..  |        . |. |.| .| | ...
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLW
Kinase AqueK215.AA IKK 118-231 32 2.1e-21 70.53 In-house 111-222 (297) Show / Hide 
Range on Protein: 118-231
Range on HMM: 111-222/297
Sequence Identity: 32% (38 aa)

CDQDVTVLLHQLGEGMKALR-AHNIVHRDIKPGNILIK-YHPKTGKMMIKLADFGFARHFKDESMKPLDLTSLAGTPVFMAPEALR-CVFN-PGVEHYDD
. ... ... ... ||. |.    ||||||||||| .  .    ||   |..||| ||   |..|     .|. ||. ...|. .   | . |  . |. 
EGHEFLQVCRDCCAGMHHLHSQNGIVHRDIKPGNIMCQKG--EDGKTIYKITDFGYAREWDDDEM----FMSFYGTEEYLHPDMYERAVLRKPHQKPYCA

KVDLWSIGALIYKVLVGQ
.||.||.|.. |..  |.
TVDYWSFGVTFYHCATGE
Kinase AqueK215.AA IKK 20-106 23 9.3e-17 54.29 In-house 1-93 (297) Show / Hide 
Range on Protein: 20-106
Range on HMM: 1-93/297
Sequence Identity: 23% (23 aa)

WDLKSLLGKGSYGNVYKGWNSQKTAEVAVKVVRKDLFRQDPKAEQNLMREIDVLKKLRQCE-------YVVHLYHVQDM---QRADAIVMVMELCEC
| ....||.|. ||||.. . .   .||||. .. ..   ... .  .||. ..|.|. ..        ...|  . .    |...  | |||.| .
WEMCDRLGQGAFGNVYHWRHKKTGRKVAVKHCNHMSW---MRCRWVWCREFEWMKRLN-HQRQFVWFPNIWCLCDIEEDMQWQICKQPVIVMEYCTG
Kinase AqueK215.AA TyrKc 20-293 21 8e-13 -15.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-293
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

WDLKSLLGKGSYGNVYKGWNSQKTAEVAVKVVRKDLFRQDPKAEQNLMREIDVLKKL-RQCEYVVHLYHVQDMQ-----RADAIVMVMELCEC-DLDHLI
  |.  || | .| ||||  .    .||||....|        .. .|||. ...||  . . .| || |   |      .. . .|||...  ||.. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KVKP--FCDQDVTVLLHQLGEGMKALRAHNIVHRDIKPGNILIKYHPKTGKMMIKLADFGFARHFKDE-------SMKPLDLTSLAG--TPVF-MAPEAL
. .   .| .|     .|  .||  |  .|..|||.   |.|..         .| .||| .|  .|.       ...    .. .    |.  ||||..
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

RCVFNPGVEH-YDDKVDLWSIGALIYKVL-VGQCGFYA-----QLNHILHILDKKGDAIAWEPS-----TAPNYGPVPKVKYIYEL-----PASLDERLS
        .. .  | | || | ... ..  ||   .        |  .. . |.|.     |.            |   . .|..      .  ..| .
-------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF------VCCPDEMYQIMKQCWHEDPEDRPT

APFKQKMNQL
  |..   ..
--FSEIHECF
Kinase AqueK215.AA Pkinase_Tyr 20-173 27 4.6e-12 41.47 Pfam 1-159 (270) Show / Hide 
Range on Protein: 20-173
Range on HMM: 1-159/270
Sequence Identity: 27% (46 aa)

WDLKSLLGKGSYGNVYKGWNS----QKTAEVAVKVVRKDLFRQDPKAE---QNLMREIDVLKKLRQCEYVVHLYHVQDMQ-RADA--IVMVMELCEC-DL
  .   ||.|..|.||||       ... .||||.. |.   .  . .   . .|||. ..|.| ... .| || |     . .   | .|||.... ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGV--CTDQGEPNQIYIVMEYMPHGDL

DHLIKVK-----PFCDQDVTVLLHQLGEGMKALRAHNIVHRDIKPGNILIKYHPKTGKMMIKLADFGFAR
..  . .     |.. .|     .|  .||  | ..|..|||.   |.|..      .. .| .||| ||
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDFGLAR