Gene AqueK216 (A.queenslandica)
AqueK216
Species: A.queenslandica
Alias: AqueK216
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK216.AA | Protein | None | 636 | None | Fasta, JSON |
| AqueK216.kin_dom | Protein Kinase Domain | None | 164 | None | Fasta, JSON |
Protein domains of AqueK216.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK216.AA | VPS15 | 25-302 | 47 | 1.2e-128 | 433.65 | In-house | 2-296 (296) | Show / Hide |
Range on Protein: 25-302 Range on HMM: 2-296/296 Sequence Identity: 47% (143 aa) DFGKPVSLGSTRFMKVARSKYTDGTEVVVKIFPKIDSSVQLQMYEKRLHDINMRLRFIA--NVLPYQNFWDSDKAAFLVRQHVQYNLYDRISTRPYLNNI .. | .|||||||||.. | | ..|||.| | | | | |. .| |. |..||| . .|||| ..||.| ||||||||||.|..| HYVK--NLGSTRFMKVCKAKHHEG-YIVVKVFVKHDDTYSLEPYKQRIEEIKKNLMQHPAFNCCPYQKVIETDKAAYMMRQYVKHNLYDRISTRPFLQMI EKKWIVFQLLKALEGCHEKK-VYHGDLKTENVLLTGWGWVFLTDFASFKPTLLPADNPADYTFFFDTSRRRNCYVAPERFVHASSYSQSSSA-------S ||||| ||.|.|||.|| .. | |||.|.||.|.| | |..|||||.|||. || |||||.||||||||||.|| |||||| . . | | EKKWIAFQTLCALEQCHKQGNVCHGDIKSENILVTSWNWCYLTDFACFKPCYLPEDNPADFTFFFDTSRRRTCYIAPERFVSNTEQDQDSNNGNMRDIHT DSFQRNKPL------TYEMDIFSLGCVTAELFLDG-QLIFNLSELLDYCQKEFSP--EPLLKKITDKYIKKMVRHMIQFK-ASDRRRPEQYLTMFKGL || |. . | .|||||.||| ||||..| | .|..| |. |. .| .| | ...|| | |. .. |||| .. | .|.|| ..| DSIDRQQNPWLFGELTPAMDIFSAGCVIAELFCEGDQPPFDYSQLCKYRSGEYHPNREQIMEKIQDEHIRNLCHHMIQKDNPMKRMSCEEYLNKWRGF |
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| Kinase | AqueK216.AA | S_TKc | 26-308 | 17 | 5.7e-13 | 13.27 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 26-308
Range on HMM: 1-231/231
Sequence Identity: 17% (51 aa)
FGKPVSLGSTRFMKVARSKYTD-GTEVVVKIFPKIDSSVQLQMYEKRLHDINMRLRFIANVLPYQNFWDSDKAAFLVRQHVQY---NLYDRISTRPY---
. . .|. | || . . .. | .| .|| . . . | ... . .| . . . . ..| .. .|.|.| |..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL
---LNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGWVFLTDF--ASFKPTLLPADNPADYTFFFDTSRRRNC----YVAPERFVHASSYSQ
.. . . .. |...||| ||.... | ||| ||.||. . ..|| | . . | |.||| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------TTFCGTPWYMAPEVL--------
SSSASDSFQRNKPLTY-EMDIFSLGCVTAELFLDGQLIFNLSELLDYCQKEFSPEPLLKKITDKYIKKMVRHMIQFKASDRRRPEQYLTMFKGLVFPEYF
. .. . |. |.||. .|.. |. | .. .| .. | ..|.. |. ..| . |.. ..|
------------GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | AqueK216.AA | Ciliate-E1 | 30-156 | 16 | 9e-12 | 35.02 | In-house | 1-143 (202) | Show / Hide |
Range on Protein: 30-156 Range on HMM: 1-143/202 Sequence Identity: 16% (24 aa) VSLGSTRFMKVARSKYTDGTEVVVKIFPKIDSSVQL-QMYEKRLHD-INMRLRFIANVLPYQNFWDSDKA--AFLVRQHVQYNLYDRIS----------- .. || ... |... . .| .||. .. ..| . .|.. . | . ... ... .... ..|.. .. . ....|.| .. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC --TRPYLNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLLT . ... .| |.|||...|. | ....|.|.| .|.| . QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILIN |
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| Kinase | AqueK216.AA | NuaK | 108-155 | 39 | 1.3e-11 | 26.26 | In-house | 85-132 (252) | Show / Hide |
Range on Protein: 108-155 Range on HMM: 85-132/252 Sequence Identity: 39% (19 aa) NLYDRISTRPYLNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLL .||| || . | | . . | |. || .. | ||| ||.|| ELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENILL |
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| Kinase | AqueK216.AA | CMGC | 99-166 | 18 | 1.5e-10 | 29.98 | In-house | 131-248 (513) | Show / Hide |
Range on Protein: 99-166
Range on HMM: 131-248/513
Sequence Identity: 18% (22 aa)
FLVRQHVQYNLYDRISTRP---------YLNNIE------------KKWIV------FQLLKALE--GCHEKK--VYHGDLKTENVLLTGW---------
.|| .....||. | . .|. . .| .. .|.|..|. || .. . | ||| ||.|..
YLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMW
-----------GWVFLTDF
| . . ||
KSEDWNPCQKNGRLKICDF
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| Kinase | AqueK216.AA | RAN | 125-166 | 37 | 1.6e-10 | 31.38 | In-house | 152-194 (324) | Show / Hide |
Range on Protein: 125-166 Range on HMM: 152-194/324 Sequence Identity: 37% (16 aa) KWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGW-VFLTDF | .. |. |.. ||.. .|| | | ||.|. | | ..|.|. KHVFLQICDAINYCHNHGIYHCDIKPENILIDGIDWNIYLCDW |
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| Kinase | AqueK216.AA | CDK | 125-166 | 34 | 1.8e-09 | 26.28 | In-house | 111-157 (284) | Show / Hide |
Range on Protein: 125-166 Range on HMM: 111-157/284 Sequence Identity: 34% (16 aa) KWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGW-----VFLTDF |.. .|||..|. ||.... | |||. | |.. | . ..|| KCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADF |
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| Kinase | AqueK216.AA | Ciliate-E2 | 108-166 | 25 | 2.6e-09 | 28.11 | In-house | 120-200 (365) | Show / Hide |
Range on Protein: 108-166 Range on HMM: 120-200/365 Sequence Identity: 25% (22 aa) NLYDRISTR-----------PYLNNIEKKWIVFQLLK---------------ALEGCHEKK-VYHGDLKTENVLLTGWGWVFLTDF .|.|.| . |.. | | | |.|. ||| .|.|. . | |.| ||.|. ....|| DLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDF |
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| Kinase | AqueK216.AA | NIM1 | 109-166 | 34 | 6.1e-09 | 22.41 | In-house | 87-144 (258) | Show / Hide |
Range on Protein: 109-166 Range on HMM: 87-144/258 Sequence Identity: 34% (20 aa) LYDRISTRPYLNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGWVFLTDF || .|... | |. | | |.. | |.. . | |.| |||..| . | . || LYTHIHQEGKLREIHCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDF |
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| Kinase | AqueK216.AA | CAMK | 109-166 | 20 | 3.1e-08 | 21.87 | In-house | 151-240 (425) | Show / Hide |
Range on Protein: 109-166 Range on HMM: 151-240/425 Sequence Identity: 20% (18 aa) LYDRISTRPY---------------LNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWG----------------W-VFLTDF |.|.| ... .. | . .. |.. |.. ||.... | ||| ||.||. . . . ..|| LFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF |
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| Kinase | AqueK216.AA | CDK5 | 125-166 | 47 | 3.3e-08 | 21.52 | In-house | 101-142 (287) | Show / Hide |
Range on Protein: 125-166 Range on HMM: 101-142/287 Sequence Identity: 47% (20 aa) KWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGWVFLTDF | . .|||| |. |||..| | ||| | | | | || KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADF |
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| Kinase | AqueK216.AA | Pkinase | 84-155 | 25 | 0.000127 | 17.43 | Pfam | 61-141 (293) | Show / Hide |
Range on Protein: 84-155 Range on HMM: 61-141/293 Sequence Identity: 25% (21 aa) NVLPYQNFWDSDKAAFLVRQHVQY-----NLYDRIS--TRPYL--NNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLL |.. . .. ... .| ... |.|.|| . . | | .. |.|..|| ||.... | ||| ||.|. NIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI |
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| Kinase | AqueK216.AA | CMGC | 224-247 | 29 | 0.000624 | 7.78 | In-house | 313-343 (513) | Show / Hide |
Range on Protein: 224-247 Range on HMM: 313-343/513 Sequence Identity: 29% (9 aa) TYEMDIFSLGCVTAELFLD-------GQLIF |...|. |.||. ||... |. .| TTPIDMWSVGCIFAEMYTGYQSLIFRGKPLF |
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| Kinase | AqueK216.AA | Pkinase | 195-247 | 20 | 0.026079 | 9.25 | Pfam | 177-212 (293) | Show / Hide |
Range on Protein: 195-247 Range on HMM: 177-212/293 Sequence Identity: 20% (11 aa) YVAPERFVHASSYSQSSSASDSFQRNKPLTYEMDIFSLGCVTAELFLDGQLIF |.||| ... ... |..|.||. .|... |...| YMAPEVIR----------------GGQYYGPKVDMWSCGCILYEMLC-GRPPF |
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