Gene AqueK226 (A.queenslandica)

AqueK226

Species: A.queenslandica
Alias: AqueK226
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: MEKK15

Sequence

Name Sequence Type Origin Length Description Download
AqueK226.AA Protein None 887 None Fasta, JSON
AqueK226.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of AqueK226.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ank AqueK226.AA Ank 61-93 42 2.8e-09 37.75 Pfam 1-33 (33) Show / Hide 
Range on Protein: 61-93
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

SGDTALITAARNGHSNIVEYLMKSGADPTLQND
 |.|.|  |.|.|| ..|..|.. |||. .|.|
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank AqueK226.AA Ank 202-242 34 1e-06 28.51 Pfam 1-33 (33) Show / Hide 
Range on Protein: 202-242
Range on HMM: 1-33/33
Sequence Identity: 34% (14 aa)

NGRTALHLISNEGSSSVGAVQAKKVVSLLLQNGSSTNITDK
.|.|.||| .  |         ..||..|||.| . |..|.
DGFTPLHLACRCG--------HTEVVKMLLQHGADVNAQDD
Ank AqueK226.AA Ank 243-267 48 1e-06 28.35 Pfam 1-25 (33) Show / Hide 
Range on Protein: 243-267
Range on HMM: 1-25/33
Sequence Identity: 48% (12 aa)

NGYTPLHIAAKNGHTAIIVALLEEG
.|.||||.|...||| ..  ||. |
DGFTPLHLACRCGHTEVVKMLLQHG
Ank AqueK226.AA Ank 154-201 26 1.65389 6.09 Pfam 1-33 (33) Show / Hide 
Range on Protein: 154-201
Range on HMM: 1-33/33
Sequence Identity: 26% (13 aa)

EGLTPLLL-VTRDIKTFDKVHRVMKTDYDPLGVMQELLKHKADLRACDS
.| ||| | . ..                 . |...||.| ||. | | 
DGFTPLHLACRCG----------------HTEVVKMLLQHGADVNAQDD
Ank AqueK226.AA Ank 278-310 42 2e-06 27.41 Pfam 1-33 (33) Show / Hide 
Range on Protein: 278-310
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

NRDTPLIISVREGHKETAEYLLSKGADVTLTAD
. .||| . .| ||.| ...||..|||| .. |
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Kinase AqueK226.AA STE11 627-884 41 4.5e-122 411.85 In-house 1-303 (303) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-303/303
Sequence Identity: 41% (125 aa)

WKKGKLLGRGAYGKVYEGL-LDTARLIAVKEVELEVEDN-----EKALVQ---FKKIQLEVDILRSLSHKNIVQYLGTSI---NETIVYIFMEYITGGSL
|.||...|.||.|.|| .. .|| .|.|||..|.. ...     || . .   .| || |. ... |.|||||.|.|...    .  |.|||||. ||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

QSILK-RFGS--LNEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGT-VKLIDFGCAKRHCLDQSLGFH---------SVRGTPY--------
 |.|. ..|   ..|..| .|..|  .||.||| .|.|||||||||... . |. .||.|||||||.. . . . .         |..||||        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEVICGRG---YGRKSDIWSLGCTMYEMIFTRPPWGDLP--PEAAMFKIGLG-QSLPPLPKNSS------MELISLYTACLKSDPGQRPTAQEVLDH
||||||| . |   ||||.||||||||..||. ..||| ..   . ||||||| | .. ||.| . |       |.      |.. ||  ||||.. |.|
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

AFL
 |.
PFI
Kinase AqueK226.AA MEKK15 627-884 52 1.1e-119 403.92 In-house 1-264 (264) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-264/264
Sequence Identity: 52% (139 aa)

WKKGKLLGRGAYGKVYEGLLDTARLIAVKEVELEVEDNEKALVQFKKIQLEVDILRSLSHKNIVQYLGTSINETIVYIFMEYITGGSLQSILKRFGSLNE
||||..||.|||| || || .|  ||||| |||.  | |||  |..|.| |||.|..| ||||| |||..... .| |||... |||. ||. |||.|.|
WKKGNILGKGAYGTVYCGLTNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSIINRFGPLDE

KTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGTVKLIDFGCAKRHCLD-----QSLGFHSVRGTPYWMAPEVICGRGYGRKSDIWSLGCTMYEM
    .| .|. .|  |||.| |.||||||.|||. . | .|||||||||| |.      .|    |.||||||||||||   ||||||||||.|||..||
MVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETGYGRKSDIWSIGCTVFEM

IFTRPPWGDLPPEAAMFKIGLG-QSLPPLPKNSSMELISLYTACLKSDPGQRPTAQEVLDHAFL
   .||| |... |||| || . . .|.||   | .      .||  |   |||| ..| |.|.
ATRKPPWADMDRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase AqueK226.AA STE11-Unclassified 627-884 36 3.3e-111 375.74 In-house 1-308 (308) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-308/308
Sequence Identity: 36% (113 aa)

WKKGKLLGRGAYGKVYEGL-LDTARLIAVKEVELEVED--NEKALVQ-FKKIQLEVDILRSLSHKNIVQYLGTS--INETIVYIFMEYITGGSLQSILKR
|.||...|.|..|.|| .. ..|  ..|||..| .  .  .|...   .. || |. .|..|.|||||||.|..    |....|||||. |||. | |..
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

FGSLNEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGTVKLIDFGCAKRHCLD----------------QSL-GF-------HSVRGTPY---
.| ..|..|  |..|   || ||| .|.|||||||||. . . |..|| |||||| .  |                ..   .        | .||||   
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPF

WMAPEVICG--R-GYGRKSDIWSLGCTMYEMIFTRPPWGDLPP---EAAMFKIGLGQSLPPLPKNSS-----------MELISLYTACLKSDPGQRPTAQ
||||||| .    |..|||||||||||..||.  ..|| .. .   ..|..||.. .. |..| . |            |.  .  .|.. ||  ||||.
WMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTAN

EVLDHAFL
. | | |.
QLLQHPFI
Kinase AqueK226.AA STE 627-884 29 1.1e-96 327.47 In-house 1-359 (359) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-359/359
Sequence Identity: 29% (107 aa)

WKKGKLLGRGAYGKVYEGLLD----------------TARLIAVKEVELEVEDN-----EKALVQ--------FKKIQLEVDILRSLS--HKNIVQYLGT
|.. . .|.||.|.|| ..                  | ...|.|...|| ..|     |.   .        ...|. |..|.. ..  |.|||.|.|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGC

SINE-------TIVYIFMEYITGGSLQSILK-RFGSLN-------------EKTIVRYVRQMGRG-LNYLHNNGVIHRDIKGANVMVSAHGTVKLIDFGC
 ..|       . ..|.|||. |||| .|.| ..| ..             |. | ...||  .| |.|||....||||||.||...     |||.|||.
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGV

AKRHCL---------------DQSLGFHSVRGTPYWMAPEVICG------RGYGRKSDIWSLGCTMYEMIFTRPPWGDLPPEAAMFKIGLG---------
...                  ...    .. ||| ||||||| .       ||..|.||||||||. ||.  .||| |..|  ||| |  .         
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----QSLPPLPK-------------------NSSMELISLYTACLKSDPGQRPTAQEVLD--HAFL
     .  ||||                    . | |..     ||. || .||||.. |   | |.
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK226.AA S_TKc 627-884 30 5.1e-91 309.6 SMART 1-231 (231) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-231/231
Sequence Identity: 30% (84 aa)

WKKGKLLGRGAYGKVYEGLL-DTARLIAVKEVELEVEDNEKALVQFKKIQLEVDILRSLSHKNIVQYLGTSINETIVYIFMEYITG--GSLQSILKRFGS
.......|.||.|||| .   .| |. |.|..              ..|. |..||..  |.|||.....  . . .|..|||. |  |.| ...|. |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------LNEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGTVKLIDFGCAKRHCLDQSLGFHSVRGTPYWMAPEVICGRGYGR-KSDIWSLGC
      ..| .. .|..|. ..|.|.|..|.||||.| .|....   ..|..||| |..         ... |||..|||||.   |||. |.|.||.||
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

TMYEMIFTRPPWGDLPPEAAMFKIGLGQSLPPLPKNSSMELISLYTACLKSDPGQRPTAQEVLD-------HAFL
..|||.  .||.     ...|||. .           | |....   ||. || .|||| |.|        | ..
ILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK226.AA MEKK2 627-884 42 9.8e-84 284.49 In-house 1-262 (262) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-262/262
Sequence Identity: 42% (113 aa)

WKKGKLLGRGAYGKVYEGL-LDTARLIAVKEVELEVEDNEKALVQFKKIQLEVDILRSLSHKNIVQYLGTSINET--IVYIFMEYITGGSLQSILKRFGS
|..||||| ||.|.||     || | .||| |. . .||  .    . .. |...|. | |. |||| |   ..   .. |||||. |||..  || .|.
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFD-PDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGA

LNEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGTVKLIDFGCAKR--HCLDQSLGFHSVRGTPYWMAPEVICGRGYGRKSDIWSLGCTMYEM
| |.   .| ||.  |. |||.. ..||||||||..  . | ||| ||| .||      .  | .|| ||||||.|||| | ||||| |.||.|||. ||
LTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEGYGRKADVWSIGCTVVEM

IFTRPPWGDLPPEAAMFKIGLGQSLPPLPKNSSMELISLYTACLKSDPGQRPTAQEVLDHAFL
. ..||| .    ||.|||   .  | ||.  | .     . | .    .|| |.|.| | | 
LTEKPPWAEYEAMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase AqueK226.AA Pkinase 627-884 28 8.3e-82 282.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

WKKGKLLGRGAYGKVYEGLLDTARL-IAVKEVELEVEDNEKALVQFKKIQLEVDILRSLSHKNIVQYLGTSINETIVYIFMEYITGG----SLQSILK--
...|. .|.|..|.||..     .   |||..... ..... ...  ..  |. |...|.|.|||.....  ... .|. |||  ||    .| ....  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

RFGSL--NEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGTV----KLIDFGCAKRH-CLDQSLGFHSVRGTPYWMAPEVIC-GRGYGRKSDI
| |..   |... .|..|. |||.|.|..|.||||.| .|.... .|..    |..|||.|| .    .|  .... |||..||||||  |..||.|.|.
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGCTMYEMIFTRPPWGDL------PPEAAMFKIGLGQSLPPLPKNSS-------------------MELISLYTACLKSDPGQRPTAQEVLDHAFL
||.||..|||.. |||. .        . . ...|. ..   . |. .|                    |.... . ||. || .||||...| | ..
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK226.AA STE20 627-884 37 1.2e-78 267.61 In-house 1-288 (288) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-288/288
Sequence Identity: 37% (109 aa)

WKKGKLLGRGAYGKVYEGLL-DTARL----IAVKEVELEVEDNEKALVQFKKIQLEVDILRSLSHKNIVQYLGTSINE----TIVYIFMEYITGGSLQSI
... . .|.|.||||| .   .| ..    .|.| ..|| .|||.   ... || |..|.. . |.|||.|.|. . .    .  .| |||  ||||. |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ--DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDI

LKRFG---------SLNEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGTVKLIDFGCAKRHCLDQ----SLGFH--SVRGTPYWMAPEVICG
.|..          ..||. |    |.. .||.|||.|..||||||..|.... .| |||.||| .    |..    . .|   .. |||||||||||..
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVC--AQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQC

-----RGYGRKSDIWSLGCTMYEMIFTRPPWGDLPPEAAMFKIGLGQSLPP--L---PKNSSMELISLYTACLKSDPGQRPTAQEVLDHAFL
      ||. |.|||||| |  ||.  .||  |..|  |||.|  .|  ||      |.. | |.  .   ||  || .||||.. | | |.
MEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK226.AA Dicty2 627-884 39 1.7e-77 263.73 In-house 1-264 (264) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-264/264
Sequence Identity: 39% (105 aa)

WKKG-KLLGRGAYGKVYEGL-LDTARLIAVKEVELEVEDNEKALVQFKKIQLEVDILRSLSHKNIVQYLGTSINETIVYIFMEYITGGSLQSILKRFGSL
 . |   .|.|| |.|| ||   |    | | ...  . .     | . |  |...|. |.| ||| |..   .|   ||..||| .|||  |.|.|| .
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIKKFGCF

NEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGT---VKLIDFGCAKRHCLDQSLGFHSVRGTPYWMAPEVICGRG--YGRKSDIWSLGCTMY
 |  . .|..|. .|| ||| .||||||||.||  ..  |    .|| ||| |    .. .    .| |||||||||||   |     ..||||||||. 
PESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRYTVVGTPYWMAPEVIQMSGNHCCTACDIWSLGCTII

EMIFTRPPWGDLPPEAAMFKIGLGQSLPPLPKNSSMELISLYTACLKSDPGQRPTAQEVLDHAFL
|.    ||  || | .|||..   .  ||||.. | |.     .| . || ||.||.. | |  .
ELLTGNPPYWDLNPMHAMFRMVQDD-HPPLPNDISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase AqueK226.AA YSK 627-884 40 1e-76 230.44 In-house 1-257 (257) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-257/257
Sequence Identity: 40% (107 aa)

WKKGKLLGRGAYGKVYEGL-LDTARLIAVKEVELEVEDNEKALVQFKKIQLEVDILRSLSHKNIVQYLGTSINETIVYIFMEYITGGSLQSILKR--FGS
..|    ||| .| || |    | | .|.| ..||  . |  .     || |. .| ..   .| .|.|.    |   | |||  |||. . .|.   |.
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIED-----IQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQ

LNEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGTVKLIDFGCAKRHCLDQSLGFHSVRGTPYWMAPEVICG--RGYGRKSDIWSLGCTMYEM
. || |    |    || ||| . .|||||| ||| .|.|| ||| ||| |  .  |...      ||||||||||||    .|  | |||||| | |||
FDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVA-GQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEM

IFTRPPWGDLPPEAAMFKIGLGQSLPPLPK-NSSMELISLYTACLKSDPGQRPTAQEVLDHAFL
    ||  |. |. .|| |   .  | | . ..|  ..    .||. || |||.|.| | | | 
AKGEPPYCDYHPMRVMFLI-PKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase AqueK226.AA ASK 632-884 40 5.9e-69 228.45 In-house 1-254 (254) Show / Hide 
Range on Protein: 632-884
Range on HMM: 1-254/254
Sequence Identity: 40% (105 aa)

LLGRGAYGKVYEGL-LDTARLIAVKEVELEVEDNEKALVQFKKIQLEVDILRSLSHKNIVQYLGTSINETIVYIFMEYITGGSLQSILK-RFGSLN--EK
 ||.|.|| || |  ..| . ||.||..   .       . . .. |. . . | |.|||||||.  ..  . |||| . |||| ..|. ..| ..  |.
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSR------YVQPLHEEIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNEN

TIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAH-GTVKLIDFGCAKRHCLDQSLGFHSVRGTPYWMAPEVI--CGRGYGRKSDIWSLGCTMYEMIFT
|.  | .|.  ||.|||.| ..|||||| ||.|  . | ||. ||| .||    . .   . .||  .||||||    ||||.  ||||.|||| ||   
TMNFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCT-ETFTGTLQYMAPEVIDQGQRGYGKPADIWSFGCTMVEMATG

RPPWGDL-PPEAAMFKIGLGQSLPPLPKNSSMELISLYTACLKSDPGQRPTAQEVLDHAFL
.||. .|  |.|||||.|. .  |..|.. | |       | . || .|..||..|   ||
KPPFHELGEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase AqueK226.AA TKL 633-882 21 7.4e-66 225.1 In-house 1-364 (364) Show / Hide 
Range on Protein: 633-882
Range on HMM: 1-364/364
Sequence Identity: 21% (79 aa)

LGRGAYGKVYEGLLDT---------ARLIAVKEVELEVEDNEKALVQ--------------------FKKIQLEVD-ILRSLSHKNIVQYLGTSINETI-
.|.|..|.|| | .           .. .|||    . .|..    |                    |..   |.  ....|.| ||||..| .....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VYIFMEYITGGSLQSILKRFGSLNEKTIVRYVRQMGRGLNYLHNNG--------VIHRDIKGANVMVSAHGT--------------VK
             .| |||. |||| ..|          ..| .... ||.||||...        .||||.| .|..|  ..|              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LIDFGCAKRHCLDQSLGFHS------------------VRGTPYWMAPEVICGR----------------GYGRKSDIWSLGCTMYEMIFTRPPWGDLPP
. ||| ..... ...    .                  ..|||.||||||. |                  |  |.|..| |  ..|..  ..|. |.|.
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

E---------AAMFKIGLGQSLPPLP------------KNSSMELISLYTACLKSDPGQRPTAQEVLDHA
.         . . .... .  ||.|            ..   ....| . | ..|| .||..||.|.. 
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK226.AA Pkinase_Tyr 627-884 30 1.9e-41 141.0 Pfam 1-270 (270) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-270/270
Sequence Identity: 30% (87 aa)

WKKGKLLGRGAYGKVYEGLLD-----TARLIAVKEVELEVEDNEKALVQ--FKKIQLEVDILRSL-SHKNIVQYLGTSI-----NETIVYIFMEYITGGS
 ..|| ||.||.|.||.| ..     |    ||| .  |         |   ..   |. |...| .|.|||...|  .     |   .|| |||  .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGD

LQSILKR----FGSLNEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGTVKLIDFGCAKRH------CLDQSLGFHSVRGTPYWMAPEVICGR
| . |..     ..|. |... . .|  .|..||.... ||||.   |..|.  ..||  ||| |. .         .. |   ..    |||||.|  .
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIK----WMAPECINYG

GYGRKSDIWSLGCTMYEMIFT--RPP-WGDLPPEAAMFKI-GLGQSLPPLPKNSSMELISLYTACLKSDPGQRPTAQEVLDHAFL
 .  |||.|| | .|.| |||  . | . ....|  . .|   |. .|. |.| . |. .| . | . || .||| .|.  | .|
KFTTKSDVWSFGVLMWE-IFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC-PENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase AqueK226.AA TyrKc 627-884 25 1.8e-37 131.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 627-884
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

WKKGKLLGRGAYGKVYEGLLDTARLIAVKEVELEVEDNEKALVQFKKIQLEVDILRSL--SHKNIVQYLGTSINE-------TIVYIFMEYITGGSLQSI
 ..|| ||.||.|.||.| ..  .  ||| .  .           . .  |  |...|  .|.|||. .|  . .         ..| |||  .|.|.. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LKRFGS-LNEKTIVRYVRQMGRGLNYLHNNGVIHRDIKGANVMVSAHGTVKLIDFGCAKRHCLD------QSLGFH----SVR--GTPYWMAPEVICGRG
|.. .  |. |. . .  |  .| .||| ...||||.   |..|.. .|||  ||| .. .  |      ..   .    . .      |||||.|  . 
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YGRKSDIWSLGCTMYEMI-FTRPPWGD-----LPPEAAMFKIGLGQSLPPLPKN-------SSMELISLYTACLKSDPGQRPTAQEVLDHAFL
.  |||.|| | .|.|.  .  .|. .     .... .. ..  |  .|. | .        . |. .. . | . || .||| .|.  | ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF