Gene AqueK245 (A.queenslandica)

AqueK245

Species: A.queenslandica
Alias: AqueK245
External Links:
Annotation:

Classification

Group: STE
Family: STE7
Subfamily: MEK4

Sequence

Name Sequence Type Origin Length Description Download
AqueK245.AA Protein None 255 None Fasta, JSON
AqueK245.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of AqueK245.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK245.AA STE7 8-247 49 2.7e-141 475.68 In-house 1-266 (288) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-266/288
Sequence Identity: 49% (132 aa)

LDVEEELGRGQYGQVNRMKHKPTGKIMAVKRIRATPDQ-AENKRLLMDYNVAMRSIDCPFTITFYGALFREGD--VWICMELMD-KSLDKLYQLVYKK--
| . .|||.| ||.|. | |||.||||||||||.| .. .|.|..||. .| ... |||....||||...|||  .|||||.||  .|||.| .|.|.  
LEHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNNDPEEQKQILMELDVLHKCNDCPYIVQFYGAFYTEGDDCIWICMEYMDGGCLDKFYKRVKKVYR

--LNEKIPEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVNSL--AKTDIGCRPYLAPERIYGGQHKYDHRSDVWSLG
   . .||| |.||.| ...|.|.|||......||||||||||.|..|..|||||||.|.||.|.  |.|..||.|| ||||| | . .|| ||||||||
GIKKGRIPEQILGKIAVAVIKGLHYLHEKHKIIHRDVKPSNILVNSRGQVKLCDFGICGQLVDSMDAATTFVGCQPYMAPERIDGNKQHYDVRSDVWSLG

ITL-CELATGEFPYPPYRN-----------------LFEQIKLVVEG-APPQLPDDGTFSEDFRDFVSK
||. .|.|||..|||  ..                  |||.. .|..  ||.||   .||..|.|||.|
ITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPEMAIFEQLTCIVNENPPPRLP---KFSPEFQDFVNK
Kinase AqueK245.AA MEK3 8-247 57 7.6e-140 470.89 In-house 1-243 (264) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-243/264
Sequence Identity: 57% (139 aa)

LDVEEELGRGQYGQVNRMKHKPTGKIMAVKRIRATPDQAENKRLLMDYNVAMRSIDCPFTITFYGALFREGDVWICMELMDKSLDKLYQLVYKKLNEKIP
. | .||||| || |  |.|...| ||||||||.|    | ||.|||  ..||| |||.|..||||.|||||||||||.|| .|||.|. |||  . .||
MVVICELGRGAYGIVDKMRHRQSGTIMAVKRIRMTVNSQEQKRMLMDMDICMRSSDCPYTVHFYGAMFREGDVWICMEVMDTCLDKFYRHVYKPHGMHIP

EVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVNSLAKT-DIGCRPYLAPERIYGGQHK--YDHRSDVWSLGITLCELA
| | ||.| |  .|| |.|  |.| ||||||||.|||..| .|.||||| | ||.| ||| | ||.|| ||||| .      || .|||||||||. |.|
EDILGKIAMSIVSALHYMHEQLKVIHRDVKPSNVLINHHGQVKMCDFGISGYLVDSMAKTIDAGCKPYMAPERIDPEMNQKGYDVKSDVWSLGITMIEMA

TGEFPYPPYRNLFEQIKLVVEGAPPQLPDDGTFSEDFRDFVSK
.| .||   .  |.| | |||. ||||| .  ||.|. ||...
IGRYPYDNWHTPFQQLKQVVEEPPPQLPMEKGFSPDCQDFINQ
Kinase AqueK245.AA MEK4 8-247 51 2.5e-136 447.57 In-house 1-254 (275) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-254/275
Sequence Identity: 51% (131 aa)

LDVEEELGRGQYGQVNRMKHKPTGKIMAVKRIR-ATPD-----QAENKRLLMDYNVAMRSIDCPFTITFYGALFREGDVWICMELMDKSLDKLYQLVYKK
|  ..|.|.| .| || | ||..||||||||||  . |     . | |||||.  | |.| .||  . ||||.|.||| |||||||| |.||.|  ||..
LQDLGEIGNGAFGTVNKMWHKESGKIMAVKRIRCNNVDPDDAFHKEQKRLLMEHDVVMKSENCPYIVKFYGACFKEGDCWICMELMDISMDKFYKYVYMV

LNEKIPEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVNSLAKT-DIGCRPYLAPERIYG--GQHKYDHRSDVWSLGI
 ...||| |.|. .  | .|| ||  .... ||||||||||.. .| .||||||| |.||.| ||| | |||||.|||||     . .|| |||||||||
QKSRIPENIMGHITVCTVDALNYLKETHKIIHRDVKPSNILLDRHGCVKLCDFGICGQLVDSIAKTHDAGCRPYMAPERIDPEQNMDGYDIRSDVWSLGI

TLCELATGEFPYPPYR--NLFEQIKLVVEGAPPQLPDDGT---FSEDFRDFVSK
|. |.|||.|||. .   ..|.||. ||.| ||.|  |     .|... .|. .
TMYEVATGKFPYRKWNDASVFDQICMVVKGDPPILHHDHHDMHYSMPMCRFINT
Kinase AqueK245.AA MEK7 8-247 47 6.4e-94 318.33 In-house 1-248 (269) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-248/269
Sequence Identity: 47% (117 aa)

LDVEEELGRGQYGQVNRMKHKPTGKIMAVKRIRATPDQAENKRLLMDYNVAMRSIDCPFTITFYGALFREGDVWICMELMDKSLDKLYQLVYKKLNEKIP
|   ...| |  |.| .|.|| .| |||||  | |    |||| |||  |   . |||. .. .|.. .. |||||||.|   .|||  ....   . ||
LHHIGDMGHGSCGHVWKMRHKSSGVIMAVKQMRRTGNKEENKRILMDLDVMCMCHDCPYIVQCFGYFMTDSDVWICMECMSTCCDKLLKRIKHPKLDFIP

EVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVNSLAKT-DIGCRPYLAPERIYG---GQHKYDHRSDVWSLGITLCEL
| |.|||  .. .|| || .  ..|||||||||||.  .| ||||||||.| .| | |.|   || .| |||||      . ||| |.||||||||| ||
EQIIGKMVVAIINALHYLKEKHGIMHRDVKPSNILLDWRGNIKLCDFGISGRMVDSKAHTRSAGCPAYMAPERIDPPDPNNPKYDIRADVWSLGITLVEL

ATGEFPYPPYRNLFEQIKLVVEG--APPQLPDDGT--FSEDFRDFVSK
||| .|||     || .  . .    || ||      || ||..|| |
ATGQYPYPGCDMEFEMMTKILNDNLEPPCLPEHMKYNFSPDFCQFVDK
Kinase AqueK245.AA STE 8-247 26 2.9e-89 302.85 In-house 1-336 (359) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-336/359
Sequence Identity: 26% (90 aa)

LDVEEELGRGQYGQVNRMKHK------PTGKI---------MAVKRIRATPDQ----------------AENKRLLMDYNVAMRSID-CPFTITFYGALF
..  |..|.| .|.| . ...      .||..         ||.|...  ...                 | ...|.. .. ... . .|. ...||. |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

REG-------DVWICMELMD-KSLDKLYQLVYKKLN---------EKIPEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAG
.||       ..|||||.||  |||.... .|....          ..|| ...... ..||.| |.. .....|||.||.|||.     .||||||..|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

ELVNSLA----------------K--TDIGCRPYLAPERIYGGQHK----YDHRSDVWSLGITLCELATGEFPY---PPYRNL------------FEQIK
 |..|.|                |  |..|.  . |||.| .....    || ..|.||||.|..|.|||. |.   .| |..            |||. 
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL-

LVVEGAPPQLPDD-----------------GTFSEDFRDFVSK
 .|.| ||.|||.                   .|..|.||..|
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINK
Kinase AqueK245.AA STE7-Unclassified 8-247 37 2.1e-84 286.74 In-house 1-279 (301) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-279/301
Sequence Identity: 37% (104 aa)

LDVEEELGRGQYGQVNRMKHKP------TGKIMAVKRIRATPD-QAENKRLLMDYNVAMRSID-CPFTITFYGALFREGD---VWICMELMDK-SLDKLY
| . ..||.| .| |   .||.      .||||| | |.   .  .  | .|.  ..  ..   .|. ...||| . |.    . ||||.||. |||.. 
LERLKYLGHGMHGTVVKCLHKNGMVIARDGKIMAWKVIPTMDNDNEFMKQILRELKT-LHKCQPHPYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKI

QLVYKKLNE-------KIPEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVNSL--AKTDIGCRPYLAPERIYGG---
  .|||. |       .|||...||.| . ...| |||..... |||.||.|||.|.||..|.||||..|.|.|.|  ||| .||  | .|||| |    
D-IYKKMYERGPIRGGWIPEPVLGKIAYQVIHGLWYLHEKHHIIHRDIKPGNILVNSKGQVKICDFGVCGQLENTLDEAKTWVGCQMYMSPERIQGQMPH

QHKYDHRSDVWSLGITLCELATGEFPYP------PYRNL--------FEQIKLVVEGAPPQLPDDG---TFSEDFRDFVSK
   |  .||.||||.|..|.|||..||.       | .         .|    .|.   |.||||.   ..|..|.||.||
RPSYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYNQNFQPENMSFWELLSCIVNFPVPRLPDDPEDIIWSKEFMDFISK
Kinase AqueK245.AA MEK1 8-212 44 1.6e-63 215.89 In-house 1-198 (297) Show / Hide 
Range on Protein: 8-212
Range on HMM: 1-198/297
Sequence Identity: 44% (91 aa)

LDVEEELGRGQYGQVNRMKHKPTGKIMAVKRIRATPDQAENKRLLMDYNVAMRSIDCPFTITFYGALFREGDVWICMELMD-KSLDKLYQLVYKKLNEKI
.....||| |  | |....|..|| ||| | |.     |  . .. . .| .     |. . |||| . .|.. |||| ||  |||    .| ||  ..|
FEKIGELGHGNGGVVMKCRHRHTGMIMARKLIHLEIKPAIRNQIIRELQV-LHECNSPYIVGFYGAFYSDGEISICMEYMDGGSLD----QVLKKA-GRI

PEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVNSLAKTDIGCRPYLAPERIYGGQHKYDHRSDVWSLGITLCELATG
|| |.||..   |. ||||.|. ..|||||||||||.| .|||||||||..| |. |.|   .| | |..|||. |    |  .||.||.|. | |.| |
PEKILGKVSVAVLRGLTYLRDKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQG--THYTVQSDIWSMGLSLVEMAIG

EFPYPP
 .| ||
RYPIPP
Kinase AqueK245.AA MEK5 8-247 43 7.8e-63 215.07 In-house 1-233 (254) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-233/254
Sequence Identity: 43% (107 aa)

LDVEEELGRGQYGQVNRMKHKPTGKIMAVKRIRATPDQAENKRLLMDYNVAMRSIDCPFTITFYGALFREGDVWICMELMD-KSLDKLYQLVYKKLNEKI
.   . || |. | | .  | |.|||.||| |         |... . ..  .  | |. | |||| | |  . || | ||  |||     .|.    .|
IRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYK-CDSPYIIGFYGAFFVENRISICTEFMDGGSLD-----MYR----CI

PEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVNSLAKTDIGCRPYLAPERIYGGQHKYDHRSDVWSLGITLCELATG
|| |.|.|. .  | |.||  .|..|||||||||.|.| .|.|||||||..  ||||...| ||   |.||||| | |  |   |||||||| . |.|||
PEHILGRMTVAIVKGLNYLW-NLKIMHRDVKPSNMLVNTQGQIKLCDFGVSTQLVNSITRTYIGTNAYMAPERISGDQ--YGIHSDVWSLGIFFMEMATG

EFPYPPY-RNL-----FEQIKLVVEGAPPQLPDDGTFSEDFRDFVSK
 ||||   |.       . .. .|.  || || |  ||| | .|. .
RFPYPQIQRDQGELMPIQLLQCIVDEHPPRLPVD-KFSEPFVHFINQ
Kinase AqueK245.AA S_TKc 8-254 23 5.2e-55 189.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-254
Range on HMM: 1-231/231
Sequence Identity: 23% (63 aa)

LDVEEELGRGQYGQVNRMKHKPTGKIMAVKRIRATPDQAENKRLLMDYNVAMRSIDCPFTITFYGALFREGDVWICMELMDK---SLDKLYQLVYK-KLN
 .. ...|.| .|.| . .|| ||.|.|.|.|.        ....   .. ..  ..|. ...|..    ......||..|    .| .. .   . .|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

EKIPEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVNSLAKTDIGCRPYLAPERIYGGQHKYDH-RSDVWSLGITLCE
 ..||  . ...  ...|| |.|.  ...|||.||.|||...  .||.||||.| .|     .| .| . |.||| .     .|.. ..|.||.|..| |
FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYE

LATGEFPYPPYRNLFEQIKLVVEGAPPQLPDDGTFSEDFRDFVSKWYV----------VLK----------L
...|. |.|   .... .|...             |....||..|  .          .|.          .
MLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase AqueK245.AA STE20 8-247 28 9.2e-51 174.96 In-house 1-267 (288) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-267/288
Sequence Identity: 28% (78 aa)

LDVEEELGRGQYGQVNRMKHKPTGKI----MAVKRIRATPD---QAENKRLLMDYNVAMRSIDCPFTITFYGALFRE----GDVWICMELMDK-SLDKLY
 .  |..|.| ||.| .  |||||..     |.|..   ..   | . .....   . |.  ..|  ...||. ...     . ||.||...  ||  ..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ-DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIM

QLVYKKLNE----KIPEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVN----SLA---KTDIGCRPYLAPERIYGGQ
. ..|. .     .. |. .  .   .|..| ||| . ...|||.|  |||....||.||.||| .. | .    . .   .| .|   ..||| | . .
KHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLH-SNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

---HKYDHRSDVWSLGITLCELATGEFPYPPYRN--LFEQIKLVVEG--APPQLPD--DGTFSEDFRDFVSK
   ..||...|.||||||..|.|.||   |||..   .  . ..  .   || | |    ..| .|.|||.|
GPDKGYDYKCDIWSLGITAIEMAEGE---PPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDK
Kinase AqueK245.AA Pkinase 8-247 25 5.2e-49 173.95 Pfam 1-272 (293) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-272/293
Sequence Identity: 25% (70 aa)

LDVEEELGRGQYGQVNRMKHKPTGKIMAVKRIRATPDQAENKRLLMD--YNVAMRSIDCPFTITFYGALFREGDVWICMELMDKS--LDKLYQLVYKKLN
. ... .|.| .|.| . .|| |||| |||.|.   .  . .. .        |.....|. ...|..  ........||....   .  |. ..  . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EKI--PEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEI----KLCDFGIAG---ELVNSLAKTDIGCRPYLAPERIYGGQHKYDHRSDVW
 ..  .|  . ...  .|..| |.|.   ..|||.||.||||...|.|    |.||||.|    .  || ..|  | ..|.||| |  |. .|....|.|
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMW

SLGITLCELATGEFPYPPYR----NLFEQIKLVVEGAPPQLPDDGTFS---------------------EDFRDFVSK
|.|..| |...|..|.|  .    |  .|......  .|.|. |   .                     |...||...
SCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW
Kinase AqueK245.AA TKL 14-233 18 2.4e-38 133.71 In-house 1-321 (364) Show / Hide 
Range on Protein: 14-233
Range on HMM: 1-321/364
Sequence Identity: 18% (60 aa)

LGRGQYGQVNRMKHKP--------TGKIMAVKRIRATPDQAENKRL---------------------LMDYNV----AMRSIDCPFTITFYGALFREGD-
.|.| .|.| . |..         ||| .|||... . |. ..| .                     ...  .     |.....|  . |.|. ..... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VWICMELMDK-SLDKLYQLVYKKLNEKIPEVIVGKMADSTLKALTYLHDEL-------QVMHRDVKPSNILINKKGE-----------
             .| ||.... ||  ...                ..| .. ... ||| .        .. ||| |..|||......           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---IKLCDFGIAGELVNSLAKTD---------------------IGCRPYLAPERIYGGQH--------------KYDHRSDVWSLGITLCELATGEFPY
   .|.||||.. .. .|  ..|                     .|   ..||| . | .               .|. ..||.| || |.|..|.. ||
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

PPYRNLFEQ---------IKLVVEGAPPQLPD
  | .  ..         .. ...| .| .|.
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPP
Kinase AqueK245.AA TyrKc 8-254 17 1.9e-13 -5.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-254
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

LDVEEELGRGQYGQVNRMKHKPTGKIMAVKRIRATPDQAENKRLLMDYNVAMRSI--DCPFTITFYGALFRE-------GDVWICMELMDKSLDKLYQLV
.  ...||.|..|.| . . |      ||| ...       .. .|.    |...  . |  . .||.   .       . ..| ||.|..  | .  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLR

YKKLNEKIPEVIVGKMADSTLKALTYLHDELQVMHRDVKPSNILINKKGEIKLCDFGIAGELVNS-------LAKTD---IGCRP-----YLAPERIYGG
... .  ..     ...    .   |||.  .. |||    |.|..... .| .||| . .. .          ..     |..       .||| |   
KHRPK--LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--N

QHKYDHRSDVWSLGITLCELATGEFPYPPY-----RNLFEQIKLVVEGAPPQLPDDG------TFSEDFRDFVSK------------WYVVLKL
 .|. . ||||| |... |. |   . .|       . .| |..| .|  .  |...      . ...  .  ..            . .. ..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK245.AA Pkinase_Tyr 186-226 36 2e-06 22.34 Pfam 190-232 (270) Show / Hide 
Range on Protein: 186-226
Range on HMM: 190-232/270
Sequence Identity: 36% (16 aa)

KYDHRSDVWSLGITLCELAT-GEFP-YPPYRNLFEQIKLV-VEG
|. . ||||| |... |. | || | ||     .| ....  .|
KFTTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDG
Kinase AqueK245.AA MEK1 216-247 46 0.000116 11.28 In-house 246-276 (297) Show / Hide 
Range on Protein: 216-247
Range on HMM: 246-276/297
Sequence Identity: 46% (15 aa)

LFEQIKLVVEGAPPQLPDDGTFSEDFRDFVSK
.|| .  .|.. ||.|| .. |||.|.|||.|
IFEMLDYIVNEPPPKLP-HRVFSEEFQDFVDK
Kinase AqueK245.AA Pkinase_Tyr 8-89 19 0.011282 9.68 Pfam 1-91 (270) Show / Hide 
Range on Protein: 8-89
Range on HMM: 1-91/270
Sequence Identity: 19% (18 aa)

LDVEEELGRGQYGQVNRMKHK----PTGKIMAVKRIRATPDQAE--NKRLLMDYNVAMRSI-DCPFTITFYGALF-REGD--VWICMELMDK
.   ..||.|..|.| . . |     |.   ||| .. . .. .   . ..   .. |... ..|  . .||.   ...   ..| ||.| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKI-MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH
Kinase AqueK245.AA Pkinase_Tyr 140-157 44 0.163217 5.75 Pfam 141-158 (270) Show / Hide 
Range on Protein: 140-157
Range on HMM: 141-158/270
Sequence Identity: 44% (8 aa)

NILINKKGEIKLCDFGIA
|.|..... .| |||| |
NCLVTENNVVKICDFGLA