Gene AqueK250 (A.queenslandica)

AqueK250

Species: A.queenslandica
Alias: AqueK250
External Links:
Annotation:

Classification

Group: TK
Family: CCK4

Sequence

Name Sequence Type Origin Length Description Download
AqueK250.AA Protein None 1513 None Fasta, JSON
AqueK250.kin_dom Protein Kinase Domain None 265 None Fasta, JSON

Protein domain

Protein domains of AqueK250.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Zf-UBR AqueK250.AA zf-UBR 38-109 32 6.7e-21 78.99 Pfam 1-78 (78) Show / Hide 
Range on Protein: 38-109
Range on HMM: 1-78/78
Sequence Identity: 32% (26 aa)

TNCTY---TKGYVSRQALYACSTCTPSSSVLAGFCLAC-SLRCHEGHDVIELYTK--RNFRCDCGNSKI-SGNP--CLLCP
..|||    .||  ||..|.| ||..  .  .. |..| .  ||.|||. ....|  |...||||...   ...  | | .
KVCTYVWKPGGY-IRQPWYRCFTCSM--DPTCCICYDCFDNSCHKGHDYVMHFSKRPRGGCCDCGDPEAPWKCEGFCKLHK
ZnF_UBR1 AqueK250.AA ZnF_UBR1 38-109 27 2.5e-15 58.18 SMART 1-79 (79) Show / Hide 
Range on Protein: 38-109
Range on HMM: 1-79/79
Sequence Identity: 27% (22 aa)

TNCTYTKGYVSRQ--ALYACSTCTPSSSVLAGFCLACSL-RCHEGHD-VIELYTKRN--FRCDCGNS--KISGNPCLLCP
..||.. .|  ..   .|.| ||.. .  ... |  |..  ||.||| . ...|.|.  |.||||..  .... .| .  
QVCTHVWTYGEHINQHWYRCHTCNMDPE-TCCCCYDCFRSNCHKGHDVCYSMCTSRHSGFYCDCGDKEAWNHDCNCKNHE
PHD AqueK250.AA PHD 128-158 30 1e-06 22.46 Pfam 1-29 (54) Show / Hide 
Range on Protein: 128-158
Range on HMM: 1-29/54
Sequence Identity: 30% (10 aa)

YC-TCNRPYPDLDDEVEDEMIQCS-VCEDWYHT
||  |..     |.. ...||.|   |..|.|.
YCCVCQKC----DWDDDGDMICCDNGCPRWFHQ
PHD AqueK250.AA PHD 128-178 28 2e-06 28.57 SMART 1-39 (39) Show / Hide 
Range on Protein: 128-178
Range on HMM: 1-39/39
Sequence Identity: 28% (15 aa)

YCTCNRPYPDLDDEVEDEMIQCS-VCEDWYHTRHLGLHPPNSFEETVCDKCM
|| |..          . ||||.  |..|||.  ||. ...  .  .|..| 
YCVCGK----------G-MIQCDPGCDRWYHQ-CLGPPLEPPDG-WYCPRCR
IGc2 AqueK250.AA IGc2 419-482 21 2e-06 29.0 SMART 1-56 (56) Show / Hide 
Range on Protein: 419-482
Range on HMM: 1-56/56
Sequence Identity: 21% (14 aa)

IEGDSVSLHCD--TGSSEAVQWFKDGVSVSVSNPNFDTSESNISISSANATIHSGTYACSLTSNQS
.||.||.| |.        ..|.| | ...        ...  .|...    .||.|.|. ... .
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP--------WNWTLTIKNVT-PEDSGYYTCYARNPWG
IG AqueK250.AA IG 413-493 19 9e-06 26.42 SMART 1-58 (58) Show / Hide 
Range on Protein: 413-493
Range on HMM: 1-58/58
Sequence Identity: 19% (17 aa)

VGPPVVIEGDSVSLHCDTGSSEAVQWFKDGVSVSVSNPNFDTSESNISISSANATIHS---GTYACSLTSNQSEVST--PFQLTVY
 .  .| ||..|.|.|       ..|.                   . | .. .  .|   ||| |  |    ...   ...|||.
PP-VTVKEGETVTLTC-VS---QIWWY-------------------LTI-NVQPE-DSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
V-set AqueK250.AA V-set 409-440 19 0.238434 6.48 Pfam 1-47 (128) Show / Hide 
Range on Protein: 409-440
Range on HMM: 1-47/128
Sequence Identity: 19% (9 aa)

PPTVVG--------PPVVIEGDSVSLHCDTG-------SSEAVQWFK
. .| .        . .| ||.||.|.|          ..  ..|..
QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYR
I-set AqueK250.AA I-set 410-449 32 0.365621 6.46 Pfam 1-46 (92) Show / Hide 
Range on Protein: 410-449
Range on HMM: 1-46/92
Sequence Identity: 32% (15 aa)

PTVVGPP---VVIEGDSVSLHCD-TGSSE-AVQWFKDGVSVSV-SN
|... .|   .| ||... . |. ||. .  |.|||||  ... |.
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSD
IG AqueK250.AA IG 522-607 16 1.7e-09 38.83 SMART 1-58 (58) Show / Hide 
Range on Protein: 522-607
Range on HMM: 1-58/58
Sequence Identity: 16% (15 aa)

LSSYSVSVESDVLLTCCTPPAIPPVHNVSWIKVDGNTRPSDGGDSSEGWSLLLSDIAVNDR---GRYRCSYEHVAAGTVQS-EEVELKVA
 . ..|.. ..| |||  .       ...|                    | . .. ..|    | |.|  .   .|...| ....|.| 
PP-VTVKEGETVTLTC-VS-------QIWWY-------------------LTI-NVQPEDSQQHGTYYCQAT---HGQYWSIQGTTLTVQ
IGc2 AqueK250.AA IGc2 528-594 22 1.1e-05 26.18 SMART 1-56 (56) Show / Hide 
Range on Protein: 528-594
Range on HMM: 1-56/56
Sequence Identity: 22% (15 aa)

SVESDVLLTCCTPP-AIPPVHNVSWIKVDGNTRPSDGGDSSEGWSLLLSDIAVNDRGRYRCSYEHVAA
    .| |||   | .  |. |..|.|   ... .       .|.| .......|.|.|.|. .. . 
HEGQSVTLTC---PATGNPDPNIHWYK---GQPLP------WNWTLTIKNVTPEDSGYYTCYARNPWG
V-set AqueK250.AA V-set 508-606 15 4.070303 2.23 Pfam 1-128 (128) Show / Hide 
Range on Protein: 508-606
Range on HMM: 1-128/128
Sequence Identity: 15% (20 aa)

NIQVSP-VDSMLYPGLSSYSVSVESDVLLTCCTP-PAIP--PVHNVSWIK-VDG---------------------------NTRPSDGGDSS-EGWSLLL
 .||..  .. . |   . .|..  .|.|.|    .  .  ... ..|..  .                            . | .  |. |   .|| .
QSQVTQHPPRGC-PW--WVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTI

SDIAVNDRGRYRCSYEHVAAGTVQSEEVELKV
|.. ..| | | |   .     .  ....| |
SNLQPSDSGTYYCAVWNC-NEDYFGHGTRLTV
I-set AqueK250.AA I-set 571-608 26 24.19662 0.28 Pfam 59-92 (92) Show / Hide 
Range on Protein: 571-608
Range on HMM: 59-92/92
Sequence Identity: 26% (10 aa)

SLLLSDIAVNDRGRYRCSYEHVAAGTVQSEEVELKVAV
.|  |..   | | |.|    ||   . . |.. .. |
TLTISNVQPDDEGKYTC----VATNSFGEAECTAELTV
IG AqueK250.AA IG 623-706 22 1.2e-12 49.22 SMART 1-58 (58) Show / Hide 
Range on Protein: 623-706
Range on HMM: 1-58/58
Sequence Identity: 22% (20 aa)

QSTVCTKPGNTVTIHCTVSGTVGNGDVSWKLGDNTLPSNERYSVDPVTNSLTITNAALSDD---GVYKCTAINDLNADSA--TVHLNMT
.. |  |.| |||..| ||       ..|.                    ||| |. ..|    |.| |.|      ...  ...|  .
PP-VTVKEGETVTLTC-VS------QIWWY--------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
I-set AqueK250.AA I-set 616-705 26 3.6e-12 43.81 Pfam 1-92 (92) Show / Hide 
Range on Protein: 616-705
Range on HMM: 1-92/92
Sequence Identity: 26% (25 aa)

PVDVTVPQSTVCTKPGNTVTIHCTVSGTVGNGDVSWKLGDNTLPS-NERYSVDPVT---NSLTITNAALSDDGVYKCTAINDLNADSATVHLNM
|. ...| . |  . | |..  |.|.|.    .|||. ..  |.. ..|.... .     .|||.|.  .| |.|.|.| | .  ...|..|. 
PKFTQKP-KDVEVQEGETARFECQVTGD-PPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV
V-set AqueK250.AA V-set 616-703 19 4.1e-09 33.26 Pfam 1-128 (128) Show / Hide 
Range on Protein: 616-703
Range on HMM: 1-128/128
Sequence Identity: 19% (25 aa)

PVDVTV-PQS----TVCTKPGNTVTIHCTVSGTV----GNGDVSWKL-GDN-------------------------TLPSNERYSVDPV--TNSLTITNA
...||. |..     |  ..| .||..|..| .     .|....|   ..                            . ... |..|   . ||||.|.
QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL

ALSDDGVYKCTAIN---DLNADSATVHL
 .|| |.| | ..|   |    . ... 
QPSDSGTYYCAVWNCNEDYFGHGTRLTV
IGc2 AqueK250.AA IGc2 629-695 26 2.1e-08 35.14 SMART 1-56 (56) Show / Hide 
Range on Protein: 629-695
Range on HMM: 1-56/56
Sequence Identity: 26% (18 aa)

KPGNTVTIHCTVSGTVGNGDVSWKLGDNTLPSNERYSVDPVTNSLTITNAALSDDGVYKCTAINDLN
..|..||. | ..|  .  ...|.  .  ||           ..|||.|....|.|.| |.| |  .
HEGQSVTLTCPATGNPDP-NIHWYK-GQPLP---------WNWTLTIKNVTPEDSGYYTCYARNPWG
IG AqueK250.AA IG 715-792 22 3.8e-11 44.28 SMART 1-58 (58) Show / Hide 
Range on Protein: 715-792
Range on HMM: 1-58/58
Sequence Identity: 22% (19 aa)

PSFVSTGLGTSKTLACSSNHDDSLATPTYFWFTPQGIEVQGPELVLNNLQYSDA---GSYNCTASSPNSLPVSS--LVSLTVL
|. |.  .| . || |  .        ...|.           |.. |.|..|.   | | |.|.   .  ..|   . |||.
PP-VTVKEGETVTLTC-VS--------QIWWY-----------LTI-NVQPEDSQQHGTYYCQAT---HGQYWSIQGTTLTVQ
IG AqueK250.AA IG 802-885 17 9e-08 33.06 SMART 1-58 (58) Show / Hide 
Range on Protein: 802-885
Range on HMM: 1-58/58
Sequence Identity: 17% (16 aa)

FPNREARLYRPLTLHCSVNVSIPDQEIEWSKENSTDKNFISSESFNSNILTIRNFSVSDV---GVYHCSYTSDTYREVKN--SVHVVLT
 |  ....  ..||.| |.      .| |.                   ||| | ...|    |.| |  |   . ...   ....  .
PP-VTVKEGETVTLTC-VS------QIWWY-------------------LTI-NVQPEDSQQHGTYYCQAT---HGQYWSIQGTTLTVQ
IGc2 AqueK250.AA IGc2 808-873 24 0.000187 17.59 SMART 1-56 (56) Show / Hide 
Range on Protein: 808-873
Range on HMM: 1-56/56
Sequence Identity: 24% (16 aa)

RLYRPLTLHCSVNVSIPDQEIEWSKENSTDKNFISSESFNSNILTIRNFSVSDVGVYHCSYTSDTY
.  ...|| | .. . || .| | |. . .         ... |||.|....| |.|.|. ..   
HEGQSVTLTCPATGN-PDPNIHWYKGQPLP---------WNWTLTIKNVTPEDSGYYTCYARNPWG
IGc2 AqueK250.AA IGc2 721-780 26 0.000223 16.85 SMART 1-56 (56) Show / Hide 
Range on Protein: 721-780
Range on HMM: 1-56/56
Sequence Identity: 26% (16 aa)

GLGTSKTLACSSNHDDSLATPTYFWFTPQGIEVQGPELVLNNLQYSDAGSYNCTASSPNS
  |.| || |  . ..   .|.  |.  | ..  . .| . | ...|.| | |.|..|..
HEGQSVTLTCPATGNP---DPNIHWYKGQPLP-WNWTLTIKNVTPEDSGYYTCYARNPWG
V-set AqueK250.AA V-set 758-791 38 0.000431 15.94 Pfam 95-128 (128) Show / Hide 
Range on Protein: 758-791
Range on HMM: 95-128/128
Sequence Identity: 38% (13 aa)

LVLNNLQYSDAGSYNCTASSPNSLPVSSLVSLTV
| ..||| || | | | ....| .   . . |||
LTISNLQPSDSGTYYCAVWNCNEDYFGHGTRLTV
V-set AqueK250.AA V-set 813-866 17 0.001988 13.65 Pfam 24-110 (128) Show / Hide 
Range on Protein: 813-866
Range on HMM: 24-110/128
Sequence Identity: 17% (15 aa)

LTLHCSVN----VSIPDQEIEWSK-ENS----------------TDKNFISSESFNSNI------------LTIRNFSVSDVGVYHC
.||.|..      . ... | |..  ..                 ...  ....|. ..            |||.| ..|| |.|.|
VTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYC
IGv AqueK250.AA IGv 768-868 12 0.004417 1.81 SMART 1-76 (76) Show / Hide 
Range on Protein: 768-868
Range on HMM: 1-76/76
Sequence Identity: 12% (14 aa)

AGSYNCTASSPNSLPVSSLVSLTVL------GPPLVKITAFPNREARLYRPLTLHCSVNVSIPDQEIEWSKENSTDKNFISSE-----SFNSNILTIRNF
  .. |..|   .     .  .         | .|  .                                   . ..  .|       | |.  ||..|.
SVTLSCKFSGFTF----YMHWYRQPPDSTPKGKGLEWMGY--------------------------------SYKGRFTWSKDNITRWSKNQFYLTMSNL

SVSDVGVYHCSY
 ..| |.| |. 
RPEDTGTYYCAR
I-set AqueK250.AA I-set 851-866 50 5.189971 2.55 Pfam 60-75 (92) Show / Hide 
Range on Protein: 851-866
Range on HMM: 60-75/92
Sequence Identity: 50% (8 aa)

LTIRNFSVSDVGVYHC
|||.|   .| |.| |
LTISNVQPDDEGKYTC
I-set AqueK250.AA I-set 758-776 42 5.296678 2.52 Pfam 60-78 (92) Show / Hide 
Range on Protein: 758-776
Range on HMM: 60-78/92
Sequence Identity: 42% (8 aa)

LVLNNLQYSDAGSYNCTAS
|   | | .|.|.| |.|.
LTISNVQPDDEGKYTCVAT
I-set AqueK250.AA I-set 920-984 37 9.7e-12 42.35 Pfam 29-92 (92) Show / Hide 
Range on Protein: 920-984
Range on HMM: 29-92/92
Sequence Identity: 37% (25 aa)

TLTVSWFKGGSPLRS-SRNVTVSNGVVQGGVASLTINSVKMSDEGSYSCLASDGVHEFNETFEIIV
. .|||||.|.|||. |. . ...    .| ..|||  |. .|||.|.| |.  . |   |.| .|
PPQVSWFKDGQPLRPDSDRHQMTYDG--DGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV
V-set AqueK250.AA V-set 892-984 14 4.6e-09 33.09 Pfam 12-128 (128) Show / Hide 
Range on Protein: 892-984
Range on HMM: 12-128/128
Sequence Identity: 14% (17 aa)

FDIISRTGIVNEILIVTCEFLGGI-SSDGTLTVSWFK----GGSPLRSS----RNVTV----------SNGVV-----QGGVASLTINSVKMSDEGSYSC
. ... |. . . .  .| .  .  .........|..    |..|   .    .....          .. |      ... .||||.....||.| | |
C-PWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYC

LASDG-VHEFNETFEIIV
 ....  . | .  . .|
AVWNCNEDYFGHGTRLTV
IG AqueK250.AA IG 894-985 15 5.8e-09 37.02 SMART 1-58 (58) Show / Hide 
Range on Protein: 894-985
Range on HMM: 1-58/58
Sequence Identity: 15% (15 aa)

IISRTGIVNEILIVTCEFLGGISSDGTLTVSWFKGGSPLRSSRNVTVSNGVVQGGVASLTINSVKMSDE---GSYSCLASDGVHEFNE--TFEIIVN
    |. . | .  || .          ...|.                         ||| .|...|.   | | | |.   ..     .....| 
PP-VTVKEGETVTLTC-VS---------QIWWY-------------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
IGc2 AqueK250.AA IGc2 900-974 22 3e-06 28.0 SMART 1-56 (56) Show / Hide 
Range on Protein: 900-974
Range on HMM: 1-56/56
Sequence Identity: 22% (17 aa)

IVNEILIVTCEFLGGISSDGTLTVSWFKGGSPLRSSRNVTVSNGVVQGGVASLTINSVKMSDEGSYSCLASDGVH
.  . .. ||.  |    . . ...|.| |.||               .  .||| .|...|.| |.|.|.  ..
HEGQSVTLTCPATG----NPDPNIHWYK-GQPLP--------------WNWTLTIKNVTPEDSGYYTCYARNPWG
IGv AqueK250.AA IGv 904-969 14 0.000972 8.4 SMART 1-76 (76) Show / Hide 
Range on Protein: 904-969
Range on HMM: 1-76/76
Sequence Identity: 14% (12 aa)

ILIVTCEFLGGISSDGTLTVSWFKG-------GSPLRSSRNVTVSNGVVQGGV---------ASLTINSVKMSDEGSYSCLA
 . ..|.| |. .     ...|..        |..|      .... .   .          ..||.......|.| | |  
SVTLSCKFSGFTF-----YMHWYRQPPDSTPKGKGLEWMGY-SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR
I-set AqueK250.AA I-set 989-1058 32 1e-14 52.43 Pfam 1-75 (92) Show / Hide 
Range on Protein: 989-1058
Range on HMM: 1-75/92
Sequence Identity: 32% (24 aa)

SFLEVPPSSVQYMEGEYLYLECRVAGKPLPKVTWLKELSHLES-DDRIIVDSNG----SLVITSIVMSDAGDYLC
   . .|..|. .||| . .||.| |.| |.|.|.|  . | . .||. .. .|    .| |. .  .|.| | |
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTC
IG AqueK250.AA IG 995-1077 20 1.4e-10 42.42 SMART 1-58 (58) Show / Hide 
Range on Protein: 995-1077
Range on HMM: 1-58/58
Sequence Identity: 20% (18 aa)

PSSVQYMEGEYLYLECRVAGKPLPKVTWLKELSHLESDDRIIVDSNGSLVITSIVMSDA---GDYLCFFDSPDGVKEH-STVTIKVS
|. |  .||| . |.| |.      ..|.                   |.| .. ..|.   |.| |      |...   ..|..|.
PP-VTVKEGETVTLTC-VS-----QIWWY-------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
IGc2 AqueK250.AA IGc2 1001-1065 29 5.3e-10 40.46 SMART 1-56 (56) Show / Hide 
Range on Protein: 1001-1065
Range on HMM: 1-56/56
Sequence Identity: 29% (19 aa)

MEGEYLYLECRVAGKPLPKVTWLKELSHLESDDRIIVDSNGSLVITSIVMSDAGDYLCFFDSPDG
 ||. . |.|...|.| | ..|.|  ..|.        .|..| |... ..|.| | |.  .| |
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP--------WNWTLTIKNVTPEDSGYYTCYARNPWG
V-set AqueK250.AA V-set 988-1076 16 7e-05 18.66 Pfam 1-128 (128) Show / Hide 
Range on Protein: 988-1076
Range on HMM: 1-128/128
Sequence Identity: 16% (21 aa)

GSFLEV-PPS----SVQYMEGEYLYLECRVA-GK----PLPKVTWLK-ELS------------HLESD-----------DRIIVDSNGS-----LVITSI
 |.... ||.    .|   ||. . |.| .  .     .   ..| .   .            |. ..           .|. . .|.|     | |...
QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL

VMSDAGDYLCFFDSPDGVKEHSTVTIKV
 .|| | | |   ... .  .. ..  |
QPSDSGTYYCAVWNCNEDYFGHGTRLTV
IGv AqueK250.AA IGv 1005-1060 15 0.002874 3.68 SMART 1-76 (76) Show / Hide 
Range on Protein: 1005-1060
Range on HMM: 1-76/76
Sequence Identity: 15% (12 aa)

YLYLECRVAGKPLPKVTWLKE-------LSHLE-----SDDRIIVDSNG---------SLVITSIVMSDAGDYLCFF
 . | |.. |. .  ..|...        . ||     . .|. .  .          .|....  ..| | | |..
SVTLSCKFSGFTF-YMHWYRQPPDSTPKGKGLEWMGYSYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR
Kinase AqueK250.AA TK 1239-1507 20 4e-84 281.81 In-house 1-486 (486) Show / Hide 
Range on Protein: 1239-1507
Range on HMM: 1-486/486
Sequence Identity: 20% (102 aa)

MLSGDIMGEGEFG---PVVKAIARHIT--------------------EDSSETLVAVKVLMSREGEEALWPSL---------------MDFSNQMR---L
   |.  |||.||    | |...| .                     ..  .| ||||.|..  ....    .               .    .|.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SSPFISKILGICADA------------EPYYVIYEYLDRGD----LKNFLFASHPSPHSEPM--------------------------------------
  | | ...|.| .             ||.... || . ||    |...| ...|  . |.                                       
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------LTQSDLLH-------------------FVSQIAEGMRYLYSQ------QIIHGDLATRNCLISSNFS-----------VKIADLG----
           ||..|||.                   .  |||.||.|| |.      ...|.|||.||||...|             .|||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----IGHDLYE-QDYYDNG------------------------SQLLPIRWMAPELLKDSNMGPA-----FSLASDIWSFGVFCWEVFSYA-QQPYEGLS
       |.|. .|||  .                        .  ||||||||| |.|    .|     |. .||.|||||..||.|.|. ...|.|.|
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

D---------EQVLRLVPSGHL------------LSLPE-EGMP--------------ALLYSLLMDCWQFDPLQRPLFTEIAPAV
.         ..|.... .|.             . .|  ...|              ...| |...||..|| .|| |...  . 
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK250.AA TyrKc 1239-1507 34 7.1e-82 279.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 1239-1507
Range on HMM: 1-280/280
Sequence Identity: 34% (107 aa)

MLSGDIMGEGEFGPVVKAIARHITEDSSETLVAVKVLMSREGEEALWPSLMDFSNQMR----L--SSPFISKILGICADA-------EPYYVIYEYLDRG
   |.. |||.|| |.|....        . ||||.| .          ..|| . .|    |  . | | ...|.| .        ||.... || . |
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

DLKNFLFASHPSPHSEPMLTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSVKIADLGIGHDLYEQ-------DYYD-----NGSQLLPIR
|||..| ...|       |. .|||.|  |||.||.|| |...|| |||.||||...|. |||.| |   |.|.        |||.     .|  .||||
DLKDYLRKHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR

WMAPELLKDSNMGPAFSLASDIWSFGVFCWEVFSYAQQPYEG-----LSDEQVLRLVPSGHLLSLPEEG-------MPALLYSLLMDCWQFDPLQRPLFT
||||| ....     |. .||.||||| .||.|.| ||||.|     .|...|...| .|. .  |...       .|. .|..  .||..|| .|| |.
WMAPECINYG----KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

EIAPAV
||    
EIHECF
Kinase AqueK250.AA Pkinase_Tyr 1295-1507 40 2.1e-75 255.98 Pfam 58-270 (270) Show / Hide 
Range on Protein: 1295-1507
Range on HMM: 58-270/270
Sequence Identity: 40% (90 aa)

MRL-SSPFISKILGICA-DAEP--YYVIYEYLDRGDLKNFLFASHPSPHSEPMLTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSVKIAD
. | . | | . .|.|  . ||  .|.. ||   |||...| .     .... || .|||..  |||.|| || |...|| |||.||||...|. |||.|
KQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICD

LGIGHDLYEQDYY--DNGSQLLPIRWMAPELLKDSNMGPAFSLASDIWSFGVFCWEVFSYAQQP-YEGLSDEQVLRLV-PSGHLLSLPEEGMPALLYSLL
 |   |.|. |||    |.  |||.||||| ....     |. .||.||||| .||.|.| .|| |.|.|.|.|....  .|. .  || . |. .|.|.
FGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK----FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPE-NCPDEIYDLM

MDCWQFDPLQRPLFTEIAPAV
..||..|| .|| |.||    
KQCWHYDPEDRPTFSEIHEQL
Kinase AqueK250.AA UTK 1238-1507 30 1.8e-74 253.7 In-house 1-296 (296) Show / Hide 
Range on Protein: 1238-1507
Range on HMM: 1-296/296
Sequence Identity: 30% (94 aa)

LMLSGDIMGEGEFGPVVKAIARHITEDSSETLVAVKVLMSREGEEALWPSLMD----FSNQMR----LSSPF-ISKILG---ICADAEPYYVIYEYLDRG
..| |.  |.|.|| | || .....| . | .|||||.     ..|  .  ..    | .  |    .. .  . ..|.   .| . || ....||  .|
VQL-GRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ----HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENG

DLKNFLFASHPSPH-SEPMLTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSN-------FSVKIADLG---IGHDLYE--------QDYYDNG
|| ..|  ..|.|   . .||  ..|.....||.|| || |....|.||| ||||. ..        ..||||.|     ....         ..|| . 
DLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA

SQ--LLPIRWMAPELLKDSNMGPAFSLASDIWSFGVFCWEVFSYAQQPYEGLSDEQVLRLVPSG-HLLSLPEEGMPALLYSLLMDCWQFDPLQRPLFTEI
..   .|||||||| | .      |...||.|||||.|||.......||.|.|..||.  |  | ...  . ...|. .| |...||. ||  || | ..
QHQDRWPIRWMAPEALTHHT---RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDL

APAV
  ..
VQQM
Kinase AqueK250.AA Musk 1245-1507 37 1.2e-66 219.2 In-house 7-282 (282) Show / Hide 
Range on Protein: 1245-1507
Range on HMM: 7-282/282
Sequence Identity: 37% (106 aa)

MGEGEFGPVVKAIARHITEDSSETLVAVKVLMSREGEEALWPSLMDFS--NQM--RLSSPFISKILGICADAEPYYVIYEYLDRGDLKNFL-----FASH
.||| || |  | |     .  ||.|||| |     ..|     |||    .|  . . | | | ||.|.   |    .||.  ||| .||     ....
IGEGAFGRVFQARAPGLVPYEEETMVAVKMLK----DDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPHRTC

PSPHSEP------------MLTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSVKIADLGIGHDLYEQDYYD-NGSQLLPIRWMAPELLKD
  .|...             |   ..|    ||| || ||   . .| ||||||||| ..  ||||| |  .  | ||||  ..    |||||.|| . .
SRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIWY

SNMGPAFSLASDIWSFGVFCWEVFSYAQQPYEGLSDEQVLRLVPSGHLLSLPEEGMPALLYSLLMDCWQFDPLQRPLFTEIAPAV
      |...||.|..||  ||.|||| ||| |.. | |.  .  |  || ||   |  .| |.  |||  |  || |..|   .
NQ----FTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPEN-CPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase AqueK250.AA InsR 1301-1509 38 1.3e-64 215.86 In-house 65-278 (278) Show / Hide 
Range on Protein: 1301-1509
Range on HMM: 65-278/278
Sequence Identity: 38% (85 aa)

FISKILGICADAEPYYVIYEYLDRGDLKNFLFASHPSPH-SEPMLT-------QSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSVKIADLG
.. . ||.|   .| ||. |  ..||||..| .  |     .| ..        ....  ...|. || || .   .| ||| |||...  | |||.| |
HVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRPEEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFG

IGHDLYEQDYYDNGSQ-LLPIRWMAPELLKDSNMGPAFSLASDIWSFGVFCWEVFSYAQQPYEGLSDEQVLRLV-PSGHLLSLPEEGMPALLYSLLMDCW
   |.|| |||  |   .||.|||||| |||      |. .||.|||||  ||. . . ||| ||| ||||. .   | .|  | |. |  .. | | ||
MTRDIYEHDYYRKGGKGMLPVRWMAPESLKDG----VFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPP-ENCPEYWQELMMMCW

QFDPLQRPLFTEIAPAVRG
|. |  ||.|..|    . 
QYQPKMRPTFLDIIHYLCD
Kinase AqueK250.AA Trk 1238-1507 34 7e-63 211.97 In-house 1-275 (275) Show / Hide 
Range on Protein: 1238-1507
Range on HMM: 1-275/275
Sequence Identity: 34% (100 aa)

LMLSGDIMGEGEFGPVVKAIARHITEDSSETLVAVKVLMSREGEEALWPSLMDFSNQMR----LSSPFISKILGICADAEPYYVIYEYLDRGDLKNFLFA
..| .. .||| || |. |   ..  .   ..|||| |      .|      ||    .    |  . | |. |.| | .|   ..||.  |||...| .
IVLKWE-LGEGAFGKVFLAECYNLCPEQDKMMVAVKTL-----KDASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQ

SHPSP----HSEP-----MLTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSVKIADLGIGHDLYE-QDYYD-NGSQLLPIRWMAPELLKD
  |      . .|      ||....|. ..||| || |. || ..| |.||||||.  |  |||.| |   |.|.  |||   .   |||||| ||    
HGPDAMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPE----

SNMGPAFSLASDIWSFGVFCWEVFSYAQQPYEGLSDEQVLRLVPSGHL-LSLPEEGMPALLYSLLMDCWQFDPLQRPLFTEIAPAV
| |   |.  ||.|||||  ||.|.| .||. .||   |   .  | . |  | .. |  .| ... ||| .| || .  .|  ..
SIMYRKFTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERP-RRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase AqueK250.AA CCK4 1304-1507 37 3e-61 205.47 In-house 66-273 (273) Show / Hide 
Range on Protein: 1304-1507
Range on HMM: 66-273/273
Sequence Identity: 37% (80 aa)

KILGICADAEPYYVIYEYLDRGDLKNFLFASHPSP----H---SEPMLTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSVKIADLGIGHD
. ||.| ..|| | . ||.| |||| || |.            | | || |  .  ..|.| ||  ||    ||.|||.||||||. . ||.  .|.  |
RLLGLCREKEPHYMVLEYVDWGDLKQFLQATRGKNNTKNKGSSSPPPLTTSQKIAICYQVALGMEHLYNNRFIHRDLAARNCLISPQMQVKVCYMGLCKD

LYEQDYYDNGSQLLPIRWMAPELLKDSNMGPAFSLASDIWSFGVFCWEVFSYA-QQPYEGLSDEQVLRLVPSGHL-LSLPEEGMPALLYSLLMDCWQFDP
.|   |.     ..|||||.||          .|  ||.| .||| ||||. . . |.|.. ..||..    | | .. | |. |  || ..  ||   |
VYNREYHHHRQKWIPIRWMPPECIFEDE----YSTKSDVWAYGVFMWEVFNQGTKMPHEQQDNDQVMQDMQAGKLMWPQP-EDCPDKLYRMMHRCWADNP

LQRPLFTEIAPAV
  |. | ||. . 
KDRHSFSEITHHL
Kinase AqueK250.AA TK-Unique 1304-1507 33 1e-59 204.55 In-house 68-294 (294) Show / Hide 
Range on Protein: 1304-1507
Range on HMM: 68-294/294
Sequence Identity: 33% (77 aa)

KILGICADA-EPYYVIYEYLDRGDLKNFLFASHP----------------SPHSEPM---LTQSDLLHFVSQIAEGMRYLYS--QQIIHGDLATRNCLIS
..||.| .  || . |.||. .|.| ..|  . |                .. ..|.   ..  ||.||  ||| || || |  ..|.|.||..||.|..
QCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLT

SNFSVKIADLGIGHDLY-EQDYYDNGS-QLLPIRWMAPELLK-DSNMGPAFSLASDIWSFGVFCWEVFSYAQQPYEGLSDEQVLRLVPSGHLLSLPEEGM
... .||.|.|.  |.| ...|  ..| . .|||||||| || .   |....  ||.|||||. ||.|.. ..|| |........... |. . .||.  
EDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCY--HGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCC

PALLYSLLMDCWQFDPLQRPLFTEIAPAV
.  .|.|.  ||| .| .|| |..|.   
SHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK250.AA DDR 1239-1507 31 1.1e-54 187.94 In-house 1-306 (306) Show / Hide 
Range on Protein: 1239-1507
Range on HMM: 1-306/306
Sequence Identity: 31% (99 aa)

MLSGDIMGEGEFGPVVKAIARHITE-----------DSSETLVAVKVLMSRE-GEEALWPSLMDFSNQM-RLS-SPFISKILGICADAEPYYVIYEYLDR
 . .  .|||.|| |   ..  .                 |||||| |  |.   ...  ....   .| ...  | | ...|.|   |||  | ||   
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKML--RPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMEN

-GDLKNFLFASHPS------------PHSEPMLTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSVKIADLG--IGHDLYEQDYYD-NG--
 |||..|. .. .                .| .  . ...   ||| ||.|| |  ..|.||||||||.  .. .||.| |  .   || ||||   |  
LGDLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFT

---SQLLPIRWMAPELLKDSNMGPAFSLASDIWSFGVFCWEVFSYA-QQPYEGLSDEQV-------LRLVPSGHLLSLPEEGMPALLY-SLLMDCWQFDP
   .. .||||||.| .    .   |. .||.|.|||  ||.|. . .|||| |.||||       .|  .   .|. |    |  .|  |.. ||. |.
GRQRHHMPIRWMAWESI----LLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPM-CPYEIYNQLMCRCWRRDQ

LQRPLFTEIAPAV
.||| | ||    
SQRPSFEEIHKFL
Kinase AqueK250.AA Ror 1304-1503 41 1.6e-52 180.8 In-house 66-271 (308) Show / Hide 
Range on Protein: 1304-1503
Range on HMM: 66-271/308
Sequence Identity: 41% (88 aa)

KILGICADAEPYYVIYEYLDRGDLKNFLFASHP-SPHS---------EPMLTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSVKIADLGI
..||.|   .||  . ||.  |||  ||    | | |             | ..| || . |||.|| || |   .| |||.||||.     |||.|.| 
CLLGVCTMDQPYCMLFEYMNHGDLHEFLIMRSPHSDHGCSSDDDRMVKSSLDHPDFLHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGL

GHDLYEQDYYDNGSQ-LLPIRWMAPELLKDSNMGPAFSLASDIWSFGVFCWEVFSYAQQPYEGLSDEQVLRLVPSGHLLSLPEEGMPALLYSLLMDCWQF
  | |  |||   .. ..|||||.||    . |   || .||||||||  ||..||  |||.| |  .|  .. . |||. | .. |.  |||   ||  
MRDIYSSDYYRMQHKSWMPIRWMSPE----AIMYGKFSEDSDIWSFGVVLWEIWSYGMQPYYGYSNQEVIEMIRNRHLLPCP-HNCPTWIYSLMIECWHE

DPLQRPLFTEI
 |  || |..|
IPSRRPRFKDI
Kinase AqueK250.AA Fer 1304-1508 29 1.9e-51 173.48 In-house 73-283 (283) Show / Hide 
Range on Protein: 1304-1508
Range on HMM: 73-283/283
Sequence Identity: 29% (66 aa)

KILGICADAEPYYVIYEYLDRGDLKNFLFASHPSPHSEPMLTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISS-NFSVK--IADLGIGHD--LY
|. |.|.| .|.... |. . |.|...|  ..        ..  ... .. |.| ||.|| |...|| |.| ||||..  .. .|  |.| |   .   |
KFYGVCVDEQPIMIVMEFCNGGSLDSYLKKNKNK-----TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDY

EQDYYDN-GSQLLPIRWMAPELLKDSNMGPAFSLASDIWSFGVFCWEVFSYAQQPYEG---------LSDEQVLRLVPSGHLLSLPEEGMPALLYSLLM-
. ||..   .. .||||.||| ...      .| ..|.||||| |||.|. ...||.|         . .... . . .|. . .|.. ||  .....| 
GYDYKMKEKACKVPIRWLAPETWQT----GIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNH-MPPEIMQIMMK

DCWQFDPLQRPLFTEIAPAVR
.||| || .|| ..||   ..
QCWQKDPEDRPTMKEICQKLK
Kinase AqueK250.AA Pkinase 1239-1503 20 1.1e-27 98.95 Pfam 1-287 (293) Show / Hide 
Range on Protein: 1239-1503
Range on HMM: 1-287/293
Sequence Identity: 20% (64 aa)

MLSGDIMGEGEFGPVVKAIARHITEDSSETLVAVKVLMSREGEEALWPSL---MDFSNQMRLSSPFISKILGICADAEPYYVIYEYLDRG----DLKNFL
   | . |.| || | |.. .   .     .||||..  |. ..  . ..   .  .   ||..|.| ...... |   .|.. ||.. |    ||. ..
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

FASHPSPHSEPML--TQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSV----KIADLGIGHDLYEQDYYDNGSQLLPI----RWMAPELLK
 .     ...  .  .  .. ... ||..|. |..|. ||| ||   |.||..|  .    ||.| |.   ..    | |.| .  .    ..||||...
ST-----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIR

DSNMGPAFSLASDIWSFGVFCWEVFSYAQQPYEGL------SDEQVLRLVPSGHLLSLPEEG-------------------MPALLYSLLMDCWQFDPLQ
    |.  . ..|.||.|. ..|...  . |. |       .. |..... .. | .  ..                    ..  . ... .|...|| .
---GGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKK

RPLFTEI
|| ...|
RPTAEQI
Kinase AqueK250.AA S_TKc 1239-1507 19 1e-25 92.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 1239-1507
Range on HMM: 1-231/231
Sequence Identity: 19% (55 aa)

MLSGDIMGEGEFGPVVKAIARHITEDSSETLVAVKVLMSREGEEALWPSLMDFSNQMRLSSPFISKILGICADAEPYYVIYEYLDR--GDLKNFLFASHP
   ... |.| || | |.. ..     .  .||.|..            .   .  ..   |.| |..... | . .|.. ||.|   |||. ..     
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI-----

SPHSEPM------LTQSDLLHFVSQIAEGMRYLYSQQIIHGDLATRNCLISSNFSVKIADLGIGHDLYEQDYYDNGSQLLPIRWMAPELLKDSNMGPAFS
  .. .       ..  .  ... ||.... |. |..||| ||   | |...   .||.| |.   |         ..     .||||.|        ..
--KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL-------GYG

L-ASDIWSFGVFCWEVFSYAQQPYEGLSDEQVLRLVPSGHLLSLPEEGMPALLYSLLMDCWQFDPLQRPLFTEIA---------PAV
  ..|.||.|.  .| ..  . |..   ........             .  . .... |.|.|| .||   |.          | .
KCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK250.AA TK-Unique 1239-1275 36 2e-06 18.71 In-house 1-38 (294) Show / Hide 
Range on Protein: 1239-1275
Range on HMM: 1-38/294
Sequence Identity: 36% (14 aa)

MLSGDIMGEGEFGPVVKAIARHITEDSSET-LVAVKVL
   ||. |||.||.| .. .. |.......  |||| |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKML
Kinase AqueK250.AA Pkinase_Tyr 1238-1275 34 0.000137 16.17 Pfam 1-36 (270) Show / Hide 
Range on Protein: 1238-1275
Range on HMM: 1-36/270
Sequence Identity: 34% (13 aa)

LMLSGDIMGEGEFGPVVKAIARHITEDSSETLVAVKVL
. .     |||.|| |.|....   .|. .. ||||.|
ITFG-KKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKML
Kinase AqueK250.AA CCK4 1240-1279 42 0.012912 4.56 In-house 1-42 (273) Show / Hide 
Range on Protein: 1240-1279
Range on HMM: 1-42/273
Sequence Identity: 42% (18 aa)

LSGDI-MGEGEFGPVVKAIARHITEDSSETLVAVKVLM-SRE
|.  | .| |||| |  | |. | .   |||| || |  ...
LQPIIQIGHGEFGEVFLAKAQGIKDGATETLVMVKALQKTKD
Kinase AqueK250.AA Fer 1239-1279 29 0.075977 2.2 In-house 1-44 (283) Show / Hide 
Range on Protein: 1239-1279
Range on HMM: 1-44/283
Sequence Identity: 29% (13 aa)

MLSGDIMGEGEFGPVVKA--IARHITEDSSE-TLVAVKVLMSRE
   |.. ||| || | |.    . . . ... . ||||| . ..
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKC
Kinase AqueK250.AA InsR 1239-1275 28 0.142329 0.94 In-house 1-39 (278) Show / Hide 
Range on Protein: 1239-1275
Range on HMM: 1-39/278
Sequence Identity: 28% (11 aa)

MLSGDIMGEGEFGPVVKAIARHITEDSSET--LVAVKVL
   .   |.| || |   ||. | .|  ..   .|.| .
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTV