Gene AqueK259 (A.queenslandica)

AqueK259

Species: A.queenslandica
Alias: AqueK259
External Links:
Annotation:

Classification

Group: TK
Family: DDR

Sequence

Name Sequence Type Origin Length Description Download
AqueK259.AA Protein None 506 None Fasta, JSON
AqueK259.kin_dom Protein Kinase Domain None 283 None Fasta, JSON

Protein domain

Protein domains of AqueK259.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK259.AA Pkinase_Tyr 222-501 37 6.9e-102 345.69 Pfam 1-270 (270) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-270/270
Sequence Identity: 37% (108 aa)

IVTDGTLGMGQFGQVHLAHTRGLSAADIGIGTDSDRTRSHEVAVKFLNQNATEKD--LKCFQKEVKYMSRL-RHRNVVQILAVCW-REEK---FIMLEFM
|. . .|| |.||.|.... .|           ..     .|||| |...|....  .. | .|.| |. | .| |.|. ..||  ..|    .| .|.|
ITFGKKLGEGAFGEVYKGTWKG-----------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYM

KNGDLQTFLQCYKSVNMGQETYNKTLSYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDNFLVKVADFGLSKNLYDSCYY-RLTGAAILPIRWMA
..||| ..|.  .       . .. |.   |..|..|||..| ||.| ..||||||||||||..|. ||..||||.. .|.  || | .| . |||.|||
PHGDLLDYLRKHR-------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMA

PEC-FYGRFSEKSDVWGFGVTLWEMFNLCLERP-YTNMKDKQIIEGA-LNGSLKVLDKPECCQTDLYHIMTSCWRPRAVDRPSFEELHKRL
||| .||.|..||||| |||..||.| ..   | | .|.. ...|    .|    ...|| |  ..|..|..||.. . |||.|.|.| .|
PECINYGKFTTKSDVWSFGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc AqueK259.AA TyrKc 222-501 34 3.4e-101 343.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-280/280
Sequence Identity: 34% (108 aa)

IVTDGTLGMGQFGQVHLAHTRGLSAADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKCFQKEVKYMSRL--RHRNVVQILAVCWR--------EEKFIML
|. . .|| |.||.|.... .                   .|||| |. .|    .. | .| . |..|  .| |.|....||          |  .| .
ITLGKKLGEGAFGEVYKGTWK------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM

EFMKNGDLQTFLQCYKSVNMGQETYNKTLSYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDNFLVKVADFGLSKNLYDS-------CYYRLTG-
|.|..|||. .|. ..            |.  .|.....|||. |.||.| ..|||||||||||||.|. ||..|||||...||         ||| .. 
EYMPHGDLKDYLRKHRPK----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH

-AAI--LPIRWMAPECF-YGRFSEKSDVWGFGVTLWEMFNLCLERPYTN-----MKDKQIIEGALNGSLKVLDKPEC--------CQTDLYHIMTSCWRP
  .   ||||||||||. ||.|..||||| |||..||.| .. . || .     |.....||   .|  . ...|.         | ...| ||..||. 
KGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYG-QQPYPGMIQQMMSNQEVIEYVKQG--YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHE

RAVDRPSFEELHKRL
 . |||.|.|.|...
DPEDRPTFSEIHECF
Kinase AqueK259.AA DDR 222-501 39 2e-98 333.33 In-house 1-306 (306) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-306/306
Sequence Identity: 39% (121 aa)

IVTDGTLGMGQFGQVHLAHTRGLSA-ADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKCFQKEVKYMSRLR-HRNVVQILAVCWREEKFIML-EFMKN-G
 .    .| |||| |||  . |.    . .   |  .     |||| | . |.. . . | ||.| ||... | |.| ...|| ..|   |. |.| | |
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

DLQTFLQCYKSVNMGQETYN--------KTLSYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDNFLVKVADFG--LSKNLYDSCYYRLTG----
||  |..  .  | | .  .         |.||  .| .. ||| .|.||.|. |.|||||.|||||| .. .|..|||  .| ||| . |||. |    
DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR

-AAILPIRWMAPEC-FYGRFSEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIE--GAL---NGSLKVLDKPECCQTDLY-HIMTSCWRPRAVDRPSFE
  . .||||||.|.   | |. |||||.||||.|||| .| |.||  . |.|.||  ...    |   .| .|  |  ..|   |..|||     |||||
QRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQSQRPSFE

ELHKRL
|.|| |
EIHKFL
Kinase AqueK259.AA TK 222-501 22 1.3e-92 310.76 In-house 1-486 (486) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-486/486
Sequence Identity: 22% (108 aa)

IVTDGTLGMGQFG---QVHLAHTRGLSAADIGIGTDSD----------RTRSHEVAVKFLNQ--NATEKDLKC--------------FQKEVKYMS--RL
|.   .|| ||||   .|...  ||..  .   . ...          .   ..|||| |    ...... .               .  | | |.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHRNVVQILAVCWREEK-------------FIMLEFMKNGD----LQTFLQ-----------CYKSVNMGQETYNKT-----------------------
.| |.|....|| ..|               |..|.|..||    |...|.           |.  .. ... .. .                       
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSK-LHHCMKGDITYSHESNSPCPEEQD

------------LSYYKLVD-------------------MSLQIADAMRYLSSC------KFIHRDLAARNCLVGDNFL-----------VKVADFG---
            |.   |..                   |..|||..|.||.|.      .|.||||||||||||.|             .|.||||   
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSKNLY-DSCYYRLTG-----------------------AAILPIRWMAPECFY----------GRFSEKSDVWGFGVTLWEMFNLCLERPYTNM
     |.. .| |. ||| ..                        . ||||||||||.           |.|..||||| |||..||.| .. | .| .|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

KD---------KQIIEGALNGSL------------KVLDKPECCQ--------------TDLYHIMTSCWRPRAVDRPSFEELHKRL
 .         ....|   .|.               . .|. |               ...| .|..||.. . |||.|..||..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK259.AA TK-Unique 222-501 31 4.7e-76 258.97 In-house 1-294 (294) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-294/294
Sequence Identity: 31% (97 aa)

IVTDGTLGMGQFGQVHLAHTRGLSAADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKCFQKEVKYMSRLR-HRNVVQILAVCWREE--KFIMLEFMKNGD
.. . ..|.|.||||. .  .|..          .. . . |||| |. |||. | . | || . |. |  | |.||.| .| . .   .|..|.. .|.
LEVGDVIGEGAFGQVWRGEVWGIW---------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGN

LQTFLQ---CY-----KSVNMG------QETYNKT-LSYYKLVDMSLQIADAMRYLSS--CKFIHRDLAARNCLVGDNFLVKVADFGLSKNLYD-SCYYR
||..|.   ..     . .|         ...... .|.  |.    ||| .| ||.|  .|..||||.|||.|..... .|..|||... .|.   | .
LQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSM

LTGAAILPIRWMAPECFY---GRF-SEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIEGALNGSLKVLDKPECCQTDLYHIMTSCWRPRAVDRPSFEE
 ..   .|||||||| ..   | . ..||||| |||..||.| |   .||..|..|. |. ..      .. ..||  ..| .| |||.  . .||||..
MCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGA-CPYPGMPWKD-IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQ

LHKRL
. .||
IKHRL
Kinase AqueK259.AA UTK 222-501 31 8.5e-74 251.48 In-house 1-296 (296) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-296/296
Sequence Identity: 31% (97 aa)

IVTDGTLGMGQFGQVHLAHTRGLSAADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKC----FQKEVK---YMSRLR-HRNVVQILAVCWREEKFIM-LE
.    .|| |.||.||.|. .          ..|..     |||| ..  |.  . ..    | .| .    |.... |.||.. ..||..|| ... .|
VQLGRQLGQGAFGEVHKARFT----------QCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTE

FMKNGDLQTFLQ-CYKSVNMGQETYNKTLSYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDN-------FLVKVADFG---LSKNLY-------
.|.||||...|. . .... .....   |.  ....|...||..| ||.||.|.|||||||||||...        ..|.||||   .|....       
YMENGDLRSYLRRHRPTPP-ACPHW---LTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNR

--DSCYYRLTGAAILPIRWMAPECFYGR--FSEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIEGALNGSLKVLDKPECCQTDLYHIMTSCWRPRAVD
  .| ||. ... ..||||||||... .  |..||||| |||..||..     .|| .| . |...  .||.   . .|. |  ..| .|..||..   .
YWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW-GRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQE

RPSFEELHKRL
||.||.| ...
RPDFEDLVQQM
Kinase AqueK259.AA Src 262-501 38 2.4e-69 234.76 In-house 25-255 (255) Show / Hide 
Range on Protein: 262-501
Range on HMM: 25-255/255
Sequence Identity: 38% (95 aa)

EVAVKFLNQNATEKDLKCFQKEVKYMSRLRHRNVVQILAVCWREE-KFIMLEFMKNGDLQTFLQCYKSVNMGQETYNKTLSYYKLVDMSLQIADAMRYLS
.|||| | .     . . |..| . |  ||| ..||..||| .||  .|  |.|..| |...|.         ..  ..|.  .|.||. |.|. | ||.
KVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK--------DGEGRHLHLPQLIDMAAQVAEGMAYLE

SCKFIHRDLAARNCLVGDNFLVKVADFGLSKNLY--DSCYYRLTGAAILPIRWMAPECF-YGRFSEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIEG
| ..||||||||| |||.| ..||||||| . .   |  |   .||  .||.|.|||.. ||||. ||||| ||. |.|..      ||  |. .. .. 
SMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAK-FPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYG-RVPYPGMTNHEVLQQ

ALNGSLKVLDKPECCQTDLYH-IMTSCWRPRAVDRPSFEELHKRL
  .|    . .|. |   ||. ||. ||. .. .|| || |.. |
VERGY--RMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK259.AA Trk 222-501 34 3.8e-69 233.55 In-house 1-275 (275) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-275/275
Sequence Identity: 34% (101 aa)

IVTDGTLGMGQFGQVHLAHTRGLSAADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKCFQKEVKYMSRLRHRNVVQILAVCWREEKFIML-EFMKNGDLQ
||  . || | ||.| ||    |. ..       |..    |||| |  .|.|.  | ||.| . .  | |...|..  ||  .. ..|  |.||.|||.
IVLKWELGEGAFGKVFLAECYNLCPEQ-------DKMM---VAVKTL-KDASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLN

TFLQCYKSVNMGQETYNK-----TLSYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDNFLVKVADFGLSKNLYD-SCYYRLTGAAILPIRWMAP
..|.    . |    |.       |   ..     |||  | |. |  |.|||.|.||||||.| .||..|||.|  .|. . |||. .   |||||| |
KYLRQHGPDAMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPP

EC-FYGRFSEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIEGALNGSLKV-LDKPECCQTDLYHIMTSCWRPRAVDRPSFEELHKRL
|   | .|.  |||| |||..|| |      |.  .  . .||  ..|  .. |..|. |  ..| ||  ||.   . | .  ..|...
ESIMYRKFTYESDVWSFGVVMWECFTYG-KQPWYQLSNHEVIECIHQG--RHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase AqueK259.AA InsR 222-503 33 9.9e-66 219.73 In-house 1-278 (278) Show / Hide 
Range on Protein: 222-503
Range on HMM: 1-278/278
Sequence Identity: 33% (96 aa)

IVTDGTLGMGQFGQVHLAHTRGLSAADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKCFQKEVKYMSRLRHRNVVQILAVCWREE-KFIMLEFMKNGDLQ
||    .| | || | .   .|.         .    |. ..|.| .| ||. ..   | .|   | .  . .||  | || | .   .  |.|. ||| 
IVLIRECGQGSFGMVYEGIAKGI--------VPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLK

TFLQCYKSVNMGQETYNK----TLSYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDNFLVKVADFGLSKNLYDSCYYRLTGAAILPIRWMAPEC
..|      .  ...  .      .. ... |  .|.| | || . ||.|||||.|||.| . | ||..|||.   .|.. |||. |   ||.|||||| 
SYLRSRRPEEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPES

FY-GRFSEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIEGA-LNGSLKVLDKPECCQTDLYHIMTSCWRPRAVDRPSFEELHKRLST
   | |. .|||| ||| ||||  |  | ||      |. .    .|  .||..||.|   .. .|  ||. .  .||.| .. . |  
LKDGVFTTHSDVWSFGVVLWEMVTLG-EQPYQGLSNEQVLKYIGMDG--NVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK259.AA Musk 222-501 34 1.5e-63 208.83 In-house 1-282 (282) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-282/282
Sequence Identity: 34% (102 aa)

IVTDGTLGMGQFGQVHLAHTRGLSAADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKCFQKEVKYMSRLRHRNVVQILAVCWREEKF-IMLEFMKNGDLQ
|.    .| | || |  |   || . .  .           |||| | ..| ..  . || |   | .  | |.|. | ||        ..|.|  |||.
IIYVRDIGEGAFGRVFQARAPGLVPYEEET----------MVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLN

TFLQCYKSVNMGQETYNKT-------------LSYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDNFLVKVADFGLSKNLYDSCYYRLTGAAIL
 ||.        . | .               |. | .  |  |||  | |||  .|.||||| ||||....  ||.||||||.. |   ||.  .    
EFLHSCSPHRTCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHI

PIRWMAPEC-FYGRFSEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIEGALNGSLKVLDKPECCQTDLYHIMTSCWRPRAVDRPSFEELHKRL
|||||.||  .| .|.  |||| .|| |||.|   |  || .|    .|    .|   .|  || |  ..| .|  ||  .  |||.| ..|. .
PIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYAL-QPYYGMTHEEVIYYIRQG--NILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase AqueK259.AA CTKA 222-501 33 4.1e-62 207.47 In-house 1-290 (290) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-290/290
Sequence Identity: 33% (99 aa)

IVTDGTLGMGQFGQVHLAHTRGLSA---ADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKCFQKEVKYMS--RLRHRNVVQILAVCWREE-KFIMLEFMK
      .| |..|||  |  ..      |    |.|        |||| | ..||| | . |  |.   |   . | ||.  | || ...  .   |.| 
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKD--------VAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQ

NGDLQTFLQCYKSVN-----------MGQETYNKTLSYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDNFLVKVADFGLSKNLYDS-CYYRLTG
 |||. .|.   .             .        .. .  | |  |||. | ||..  |.|||||.||||.|    .|.||||... |     || .  
YGDLHCYLRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSS

AAILPIRWMAPECF-YGRFSEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIEGALNGSLKVLDKPECCQTDLYHIMTSCWRPRAVDRPSFEELHKRL
  ..|.||||||    |.||  |||| ||| |||..    | |.  | |. . .  . . .. |  |  |   ||| |. ||..    ||.|| | . |
QRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMG-EKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase AqueK259.AA Ror 263-504 38 3.8e-61 209.46 In-house 32-278 (308) Show / Hide 
Range on Protein: 263-504
Range on HMM: 32-278/308
Sequence Identity: 38% (96 aa)

VAVKFLNQNATEKDLKCFQKEVKYMSRLRHRNVVQILAVCWREEKFIML-EFMKNGDLQTFLQCYKSVNMGQE-------TYNKTLSYYKLVDMSLQIAD
||.| .  .|. .  . |..|.. |..| | |.| .| ||  ..   || |.| .|||  ||   .| .           .  ..|.    .   .||| 
VAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDLHEFL-IMRSPHSDHGCSSDDDRMVKSSLDHPDFLHIAIQIAA

AMRYLSSCKFIHRDLAARNCLVGDNFLVKVADFGLSKNLYDSCYYRLTGAAILPIRWMAPEC-FYGRFSEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQ
 | ||||  |.||||||||||||.   ||..||||.   | | |||. . ...|||||.||   ||.||| ||.| |||.||| .   .  ||      .
GMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSEDSDIWSFGVVLWEIWSYGM-QPYYGYSNQE

IIEGALNGSLKVLDKPECCQTDLYHIMTSCWRPRAVDRPSFEELHKRLSTL
.||  .  .  .|  |. | |  |  |. ||    . || | . | || ..
VIE--MIRNRHLLPCPHNCPTWIYSLMIECWHEIPSRRPRFKDIHSRLRSW
Kinase AqueK259.AA S_TKc 222-505 18 1.7e-31 111.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 222-505
Range on HMM: 1-231/231
Sequence Identity: 18% (54 aa)

IVTDGTLGMGQFGQVHLAHTRGLSAADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKCFQKEVKYMSRLRHRNVVQILAVCWREEKFIM-LEFMKN--GD
     ..| | ||.|.... ..                 ..||.| ..        . ...|.. ... .| |.|... |.   ... | .|.. .  ||
YEILRKIGKGAFGKVYKCRHKK---------------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGD

LQTFLQCYKSVNMGQETYNKTLSYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDNFLVKVADFGLSKNLYDSCYYRLTGAAILPIRWMAPECFY
| .... ...       ... ..      .  ||..|. |. | ..|||||   | |. .   .|..||||.. |            .    .|||| . 
LFDYIKKRGRHG-----LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL-

GRFSE-KSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIEGALNGSLKVLDKPECCQTDLYHIMTSCWRPRAVDRPSFEELHK-----RLSTLY
  ..  |.|.| .|..|.||  || . |.    ......  .               .. ...  |..    .||.  |. .     ..    
-GYGKCKCDWWSCGCILYEM--LCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK259.AA Pkinase 222-501 20 3.8e-28 100.6 Pfam 1-293 (293) Show / Hide 
Range on Protein: 222-501
Range on HMM: 1-293/293
Sequence Identity: 20% (65 aa)

IVTDGTLGMGQFGQVHLAHTRGLSAADIGIGTDSDRTRSHEVAVKFLNQNATEKDLKCFQK----EVKYMSRLRHRNVVQILAVCWREEKFIM--LEFMK
... ...| | ||.| ..| .| .                .|||| ..   .||. |. ..    |...| ||.| |.|... .. . .. |   .|.. 
YHIGRKIGSGSFGCVYKCHHKGTGK---------------IVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCE

NG----DLQTFLQCYKSVNMGQETYNKTL--SYYKLVDMSLQIADAMRYLSSCKFIHRDLAARNCLVGDNFLV----KVADFGLSKNLYDSCYYRLTGAA
.|    || ....           .....  |.  . .. .||. .. |. |...|||||   |.|. .|  .    |..||||.| ..    .. .   
GGLYVMDLFDYIST---------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTF

ILPIRWMAPEC--FYGRFSEKSDVWGFGVTLWEMFNLCLERPYTNM------KDKQIIEGALNGSLKVLDKPECCQ------------------TDLYHI
   ...||||   ..   . |.|.|..|..|.||..   . |. .        ..|.|.  . . |.     .|.                    .. ..
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC--GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF

MTSCWRPRAVDRPSFEELHKR--L
...|...   .||..|.. .   .
IKWCLCKDPKKRPTAEQILQHPWF