Gene AqueK510 (A.queenslandica)
AqueK510
Species: A.queenslandica
Alias: AqueK510
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
AqueK510.AA | Protein | None | 401 | None | Fasta, JSON |
AqueK510.kin_dom | Protein Kinase Domain | None | 210 | None | Fasta, JSON |
Protein domains of AqueK510.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | AqueK510.AA | TKL | 28-299 | 18 | 7.4e-34 | 118.8 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 28-299 Range on HMM: 1-364/364 Sequence Identity: 18% (70 aa) ISDGAYGVVNEVKIDD---------GTLCAGKTPHEYL-----------------------VREDKTFLKKFCDEVLLHVKQHHPNIVQVIG-LHYPPS- | |..|.| | |. | |. .. .| . | ... |.... . .|||||| .| .||. IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG --------SRFIPMLIMEYLPM-T-LGNCLDKKQPMLEPEELKRPQTQYSILLGVANGLIYLHQKE------PPVYHRDLTAYNVLLTANFT-------- . ....||| | . | . . .. .. |..| |. |||... ||. ||||. |.|. |.| CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYN ------AKISDLGMSRIVAVSGE-------------------KLTAAPGNVNVMPPEAKKDNP---------------IYNHKIDVFAFGCLILHIASGQ .||.|.| || . ||. .. |. . |.||. .... |. |.||..|| .. |.... PNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC FPVPKRDSFQENPNDDTCTSYIKI-----------TEWS-RRYKYVKAILDEDDHELLPLAQQCLEDNPRDRPEMIDLVHFI | . ..... ..|. .... ..|. .. | . . .... |.|.| . .|..|| . .... . RPYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | AqueK510.AA | TK | 22-299 | 15 | 6.4e-27 | 86.65 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 22-299 Range on HMM: 1-486/486 Sequence Identity: 15% (76 aa) VEIGLKISDGAYG---VVNEVKIDDG--------------------------TLCAGKTPHEYLVREDKTFLK-------------KFCDEVLLHV--KQ ...| |. |..| .| . . .. | .| |. .| ... |. ... | . . ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG HHPNIVQVIG--LHYPPSSRFI-------PMLIMEYLPMT-----LGNCLDKKQPM-------------------------------------------- ||||||. .| .. |...| .|..||| | | . | |. | HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY -----------LEPEELKR--------------PQTQYSILLGVANGLIYLHQKEP----PVYHRDLTAYNVLLTANFT-----------AKISDLGMS- | .| . .... . . .|.|. |||.| . |||| | |.|.. | . .||.| |.| DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR -------RIVAVSGEKLTAAPGNVNV--------------------------MPPEAKKDNP--------IYNHKIDVFAFGCLILHIAS-G-QFPVPKR | . ... .. .. ... |.||. .|. .. .| ||..||.|. | . | . . . QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM DS--------------------------------FQENPNDDTCTSYIKITEWSRRYKYVKAILDEDDHELLPLAQQCLEDNPRDRPEMIDLVHFI .. . | . |... |.. . . ... |. | ||| . .|.||| . .|.... SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWM-R------YRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | AqueK510.AA | HH498 | 128-231 | 33 | 2.7e-22 | 67.14 | In-house | 120-225 (284) | Show / Hide |
Range on Protein: 128-231 Range on HMM: 120-225/284 Sequence Identity: 33% (35 aa) PQTQYSILLGVANGLIYLHQ-KEPPVYHRDLTAYNVLLTANFTAKISDLGMSRIVAVSGEK-LTAAPGNVNVMPPEAKKDNPIYNHKIDVFAFGCLILHI .| | . ||.| ||| .|. ||||. |.|. .. |.. | | || | ... .| ||| | || . . | |.||| .. | . LQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEM ASGQFP .. | HTREVP |
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Kinase | AqueK510.AA | TKL-Unique | 61-219 | 27 | 5.1e-22 | 74.55 | In-house | 36-215 (290) | Show / Hide |
Range on Protein: 61-219 Range on HMM: 36-215/290 Sequence Identity: 27% (51 aa) KTFLKKFCDEVLLHVKQH-HPNIVQVIGLHY----PPSSRFIPMLIMEYLPM-TLGNCLDKKQPML---EPEELKRPQTQYSILLGVANGLIYLHQKEPP ......| .|| . | | |||||. .| .|. ..| .|||.|. .| . |. . ... .| .... . .| |..||| .||| NEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCI---VMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP VYHRDLTAYNVLLTAN-----FTAKISDLGMSRIVAVSGEKLTAAP---------GNVNVMPPEAKKDN-PIYNHKIDVFAFG ..||||. |.|.. | . .||.| | |.. . . .. . . |. . |.|| ..| |. |.||..|| IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFG |
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Kinase | AqueK510.AA | TK-Unique | 79-222 | 28 | 1.8e-18 | 60.4 | In-house | 63-229 (294) | Show / Hide |
Range on Protein: 79-222 Range on HMM: 63-229/294 Sequence Identity: 28% (51 aa) HPNIVQVIGLHYPPSSRFIPMLIMEYLPMT-LGNCLDKKQPM-------------------------LEPEELKRPQTQYSILLGVANGLIYLHQ--KEP |||||| .| .. . .|.||||.|. | ..| ...| . |. | . .. ..|.|. ||.. |. HPNIVQCLGCCTKSD--EPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYH------FAWQIACGMEYLASQRKK- PVYHRDLTAYNVLLTANFTAKISDLGMSRIVA---VSGEKLTAAPGNVNVMPPEAKK--DNPIYNHKIDVFAFGCLI . |||| | ||||| ....||.|.||.| | | . . . . |.||. | ...... | || .||.|. -IVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLM |
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Kinase | AqueK510.AA | S_TKc | 22-299 | 19 | 6.6e-17 | 63.42 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 22-299 Range on HMM: 1-231/231 Sequence Identity: 19% (59 aa) VEIGLKISDGAYGVVNEVK-IDDGTLCAGKTPHEYLVREDKTFLKKFCDEVLLHVKQHHPNIVQVIGLHYPPSSRFIPMLIMEYLPM---TLGNCLDKKQ ||. || ||.|.| .. ...| ..| | . .... |. .. | ||||||. .. . ..|||.. .| ..|.. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRG PM-----LEPEELKRPQTQYSILLGVANGLIYLHQKEPPVYHRDLTAYNVLLTANFTAKISDLGMSRIVAVSGEKLTAAPGNVNVMPPEAKKDNPIYNH- . . . . .. .. ....| |.|.. . |||| |.||. . ||.| |..|.. | | . |.|| |.. RHGLRFPFPE-HARF------YMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKC KIDVFAFGCLILHIASGQFPVPKRDSFQENPNDDTCTSYIKITEWSRRYKYVKAILDEDDHELLPLAQQCLEDNPRDRPEMIDLVH---------FI |.|. ..||.. ..|. | | . .|. ..|.. . ..||. .|..|| .. . .. KCDWWSCGCILYEMLCGYPPFP------------QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | AqueK510.AA | UTK | 22-219 | 21 | 9.7e-16 | 50.32 | In-house | 1-227 (296) | Show / Hide |
Range on Protein: 22-219 Range on HMM: 1-227/296 Sequence Identity: 21% (51 aa) VEIGLKISDGAYGVVNEVKIDDGT---LCAGKTPHEYLVREDKTFLK----KFCDEVL---LHVKQH-HPNIVQVIGLHYPPSSRFIPMLIMEYLP-MTL |..| .. ||.|.|.. . .. . . ... .. ...|... . .| | . . | |||.....|.. . .|...|| . | VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP---WMIVTEYMENGDL GNCLDKKQPMLEPEELKRPQTQ-YSILLGVANGLIYLHQKEPPVYHRDLTAYNVLLTAN-------FTAKISDLG---MSRIVA---------VSGEKLT ..| . | ...... .| . . .|.|. |||.. . |||| | |.|.... ..||.|.| ||| |. | . RSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCG--FVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA AAPGNVNV--MPPEAKKDNPIYNHKIDVFAFG . . . . | ||| .. . .| ||..|| QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFG |
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Kinase | AqueK510.AA | TyrKc | 22-299 | 23 | 1.4e-15 | 29.37 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 22-299 Range on HMM: 1-280/280 Sequence Identity: 23% (72 aa) VEIGLKISDGAYGVVNEVKIDDGTLCAGKTPHEYLVREDKTFLKKFCDEVLLHVKQ--HHPNIVQVIGLHYPPSSRF----IPMLIMEYLPM-TLGNCLD .. | |. ||.|.| . . . . .| |. .|. .. |..| . | ||||||. .| .. .| .|..||| | | . | ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR KKQPMLEPEELKRPQTQYSILLGVANGLIYLHQKEPPVYHRDLTAYNVLLTANFTAKISDLGMSRIVAVS------GEKLTAA---PGN--VNV--MPPE |..| ... |. . .|.| |||.| .. |||| | |.|...|.|.|||| |.|| . .. ... |. . . |.|| KHRPK------LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE AKKDNPIYNHKIDVFAFGCLILHIASGQFPVPKRDSFQENPNDDTCTSYIKITEWSRRYKYVKAILD-------EDDHELLPLAQQCLEDNPRDRPEMID . ... ....| ||..|| .. | . . . . .| | . . |. .. .. . . . |. . .|| . .| ||| . . CINYG-KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE LVHFI ..... IHECF |
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Kinase | AqueK510.AA | Pkinase | 22-290 | 20 | 3.7e-15 | 54.66 | Pfam | 1-282 (293) | Show / Hide |
Range on Protein: 22-290 Range on HMM: 1-282/293 Sequence Identity: 20% (61 aa) VEIGLKISDGAYGVVNE-VKIDDGTLCAGKTPHEYLVREDKTFLKKFCD--EVLLHVKQHHPNIVQVIGLHYPPSSRFIPMLIMEYLPMTLGNCLDKK-- .|| || |..|.| . .....| . | |. ...|.. ... |. .. . .|||||. .. . ... ..|||....| ..| . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKI--IKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY---MVMEYCEGGLY-VMDLFDY -----QPML--EPEELKRPQTQYSILLGVANGLIYLHQKEPPVYHRDLTAYNVLLTANFTA----KISDLGMSRIV-AVSGEKLTAAPGNVNVMPPEAKK . . ...|.|. ... .. || |.|.. . |||| |.|. | . ||.| | .. . ... .| | . |.|| . ISTWRHGCFYFSEWECKF------YMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR DNPIYNHKIDVFAFGCLILHIASGQFPVPKR------DSFQENPNDDTCTSYIKITEWSRRY--------KYVKAILDEDDHELLPLAQQCLEDNPRDRP ... | .|.|....||.. ..|..| | . | | .. . . .|.... . . .. . |.. . ||. .| .|| GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHF-HWTF-HNWSEECKDFIKWCLCKDPKKRP |
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Kinase | AqueK510.AA | Fer | 134-300 | 25 | 5.3e-15 | 47.63 | In-house | 116-283 (283) | Show / Hide |
Range on Protein: 134-300 Range on HMM: 116-283/283 Sequence Identity: 25% (47 aa) ILLGVANGLIYLHQKEPPVYHRDLTAYNVLLTA-NFTAK--ISDLGMSRIVAVSGEKLTAAP--GNVNV--MPPEAKKDNPIYNHKIDVFAFGCLILHIA .....|.|. |||.| . |||. | |.|... .. | ||| |||| .. |.. . .. |.. ..||. . . ||..| ||..||... | MCYQAACGMEYLHSKN--CIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQ-TGIYSPKTDVWSFGVMCWEIF S-GQ--FPV-PKRDSFQENPNDDTCTSYIKITEW--SRRYKYVK-----AILDEDDHELLPLAQ-QCLEDNPRDRPEMIDLVHFIE . |. .| | . .| |.. ..| ...| . ... |. . || . .| ||| | .... .. TNGAEPYPGQPH-G--------------MKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
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Kinase | AqueK510.AA | Dicty5 | 130-219 | 33 | 8.4e-15 | 47.38 | In-house | 105-190 (260) | Show / Hide |
Range on Protein: 130-219 Range on HMM: 105-190/260 Sequence Identity: 33% (30 aa) TQYSILLGVANGLIYLHQKEPPVYHRDLTAYNVLLTANFTAKISDLGMSRIVAVSGEKLTAAPGNVNVMPPEAKKDNPIYNHKIDVFAFG .| .. ...|... .|| . . |||| |.|.| |...|| | | || |. . | | . | .| . .| | | ||..|| QQLHMAIDIAQSMRHLHSMN--IIHRDLKSMNFLITENWKIKIIDFGTSRFVDNR-YHMTMHVGTQCWMACELFNGQP-YHQKCDVYSFG |
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Kinase | AqueK510.AA | Pkinase_Tyr | 78-222 | 29 | 1.1e-14 | 50.36 | Pfam | 62-204 (270) | Show / Hide |
Range on Protein: 78-222 Range on HMM: 62-204/270 Sequence Identity: 29% (45 aa) HHPNIVQVIGLHY---PPSSRFIPMLIMEYLPM-TLGNCLDKKQPMLEPEELKRPQTQYSILLGVANGLIYLHQKEPPVYHRDLTAYNVLLTANFTAKIS ||||||. .| . |. ....||| | | . | |. ... |. .. .. . .|.|. ||..| |||| | |.|.| |...||. HHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDYLRKHR--EDKQPLTMKD-LLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKIC DLGMSRIVAVSG---EKLTAAPGNVNVMPPEAKKDNPIYNHKIDVFAFGCLI | |..| . . | . .. . |.||. ... ...| || .|| |. DFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVLM |
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Kinase | AqueK510.AA | MLK | 136-219 | 31 | 2.1e-13 | 43.0 | In-house | 131-223 (291) | Show / Hide |
Range on Protein: 136-219 Range on HMM: 131-223/291 Sequence Identity: 31% (30 aa) LGVANGLIYLHQKEP-PVYHRDLTAYNVLLTA------NFTAKISDLGMSRIVAVSGEK-LTAAPGNVNVMPPEA--KKDNPIYNHKIDVFAFG | .|.|. |||...| |. |||| |.|... . |.||.| | || . .. . . ..|.. | ||. .. . |. | ||. .| LQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWG |
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Kinase | AqueK510.AA | LRRK | 128-231 | 30 | 3.2e-12 | 39.51 | In-house | 163-282 (351) | Show / Hide |
Range on Protein: 128-231 Range on HMM: 163-282/351 Sequence Identity: 30% (37 aa) PQTQYSILLGVANGLIYLHQKEPPVYHRDLTAYNVLL---T---------ANFTAKISDLGMSRIVAVSGEK-LTAAPGNVNVMPPEAKKDN--PIYNHK ..... | | .| |. ||| . ||. ||||. |.|| . |. .|||.| | ||. .. ... . || | || ..| |. | WMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEK IDVFAFGCLILHIASGQ-FP .|...|| .. .. ..| .| VDCYSFGMILWELLTRQHHP |
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Kinase | AqueK510.AA | UTK | 272-299 | 32 | 0.001518 | 8.0 | In-house | 269-296 (296) | Show / Hide |
Range on Protein: 272-299 Range on HMM: 269-296/296 Sequence Identity: 32% (9 aa) HELLPLAQQCLEDNPRDRPEMIDLVHFI |.. | ..| . .|..|| . ||| .. HPVYRLMHRCWHYDPQERPDFEDLVQQM |
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Kinase | AqueK510.AA | MLK | 279-299 | 28 | 0.002882 | 7.34 | In-house | 271-291 (291) | Show / Hide |
Range on Protein: 279-299 Range on HMM: 271-291/291 Sequence Identity: 28% (6 aa) QQCLEDNPRDRPEMIDLVHFI .|| ...|..|| . | . KQCWNQDPHKRPSFRQIVQHL |
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Kinase | AqueK510.AA | LRRK | 272-301 | 26 | 0.005592 | 6.36 | In-house | 322-351 (351) | Show / Hide |
Range on Protein: 272-301 Range on HMM: 322-351/351 Sequence Identity: 26% (8 aa) HELLPLAQQCLEDNPRDRPEMIDLVHFIEN |... | |.| . .|..|| ... | ... HMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
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Kinase | AqueK510.AA | HH498 | 271-299 | 27 | 0.054394 | 1.65 | In-house | 256-284 (284) | Show / Hide |
Range on Protein: 271-299 Range on HMM: 256-284/284 Sequence Identity: 27% (8 aa) DHELLPLAQQCLEDNPRDRPEMIDLVHFI .| . | |.| . .| .||. . | . PHHWSNLIQMCWHPCPENRPDFDQIVTIL |
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Kinase | AqueK510.AA | TKL-Unique | 279-299 | 33 | 0.073696 | 2.56 | In-house | 270-290 (290) | Show / Hide |
Range on Protein: 279-299 Range on HMM: 270-290/290 Sequence Identity: 33% (7 aa) QQCLEDNPRDRPEMIDLVHFI ||| ..| .|| .. .| . QQCWHHDPSQRPSFDEIIHRL |
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Kinase | AqueK510.AA | Pkinase_Tyr | 279-299 | 28 | 0.675871 | 3.66 | Pfam | 250-270 (270) | Show / Hide |
Range on Protein: 279-299 Range on HMM: 250-270/270 Sequence Identity: 28% (6 aa) QQCLEDNPRDRPEMIDLVHFI .|| . .| ||| . ...... KQCWHYDPEDRPTFSEIHEQL |
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IBR | AqueK510.AA | IBR | 334-371 | 32 | 3.5e-10 | 32.99 | Pfam | 1-35 (44) | Show / Hide |
Range on Protein: 334-371 Range on HMM: 1-35/44 Sequence Identity: 32% (13 aa) SCPT--CNYIIEHAPDGSNRSSKFVVCPRCKKEYCFLCLQ ||. |.|.||| ..... . ||.|..|.|..|.. WCPNPDCQYWIEHEDGCNH-----MTCPKCGHEFCWNCKE |