Gene AqueK564 (A.queenslandica)

AqueK564

Species: A.queenslandica
Alias: AqueK564
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-B

Sequence

Name Sequence Type Origin Length Description Download
AqueK564.AA Protein None 763 None Fasta, JSON
AqueK564.kin_dom Protein Kinase Domain None 238 None Fasta, JSON

Protein domain

Protein domains of AqueK564.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_1 AqueK564.AA Kelch_1 15-31 29 39.380467 0.65 Pfam 29-45 (45) Show / Hide 
Range on Protein: 15-31
Range on HMM: 29-45/45
Sequence Identity: 29% (5 aa)

EVYHLPTSRWEQKPTTG
|.|.. | .|.. |. .
ECYDPETNQWTRCPPMP
Kelch_1 AqueK564.AA Kelch_1 36-83 20 1.7e-05 23.48 Pfam 1-45 (45) Show / Hide 
Range on Protein: 36-83
Range on HMM: 1-45/45
Sequence Identity: 20% (10 aa)

GILGYVSAAIGNEIFYFGGGCNHDSCYHNSLYSFNVDTFTWRELSPTT
   |. .......|. .|| ..    | || ......| .|....| .
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK564.AA Kelch_2 36-83 17 0.956003 6.96 Pfam 1-51 (51) Show / Hide 
Range on Protein: 36-83
Range on HMM: 1-51/51
Sequence Identity: 17% (9 aa)

GILGYVSAAIGNEIFYFGGG---CNHDSCYHNSLYSFNVDTFTWRELSPTT
.  . .|. .|. |. |||      ...|...... .. .| .|.....  
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_2 AqueK564.AA Kelch_2 218-263 25 0.000261 20.5 Pfam 1-51 (51) Show / Hide 
Range on Protein: 218-263
Range on HMM: 1-51/51
Sequence Identity: 25% (14 aa)

KQYAHSSVFINSKLGPHLLVVGGY---------SKDDCWLLDVNKRRWKQLSNLP
 .| |.|. ...|    ..|.|||         .  | |..| ...||. .. .|
PRYCHASCVPGGK----IYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK564.AA Kelch_1 231-263 16 0.021931 12.32 Pfam 10-45 (45) Show / Hide 
Range on Protein: 231-263
Range on HMM: 10-45/45
Sequence Identity: 16% (6 aa)

LGPHLLVVGGYSK---DDCWLLDVNKRRWKQLSNLP
.. .. |.||..    .... .|. . .|......|
HNGKIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK564.AA Kelch_2 268-291 37 31.135258 1.21 Pfam 1-19 (51) Show / Hide 
Range on Protein: 268-291
Range on HMM: 1-19/51
Sequence Identity: 37% (9 aa)

DRRCHSMSVWSITPTIDWIIVFGG
 | ||...|.      ..|.||||
PRYCHASCVP-----GGKIYVFGG
Kinase AqueK564.AA TKL 531-758 19 8.3e-43 148.53 In-house 1-364 (364) Show / Hide 
Range on Protein: 531-758
Range on HMM: 1-364/364
Sequence Identity: 19% (72 aa)

LGRGGWAEVRVASFHG----------LEVAAKVLHDTIISEYNL-------------------------SLFSRDINIASKIRHPNLLQFIGATTEGN--
.|.|| .||  . ..|           .|| |... .  .| ..                           . . |.. |..||||..||.|. ....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PIILTELM-PTSLRKELETGGLAYHAVLDISLDVAFALNYLHLFKP-----HPILHRDVSSANVLLQSIGH-----------GWRAKL
            . | .|..   ||.  |       |  ....||.| ..||||  .|      ||.|||  |.|.|. . ..            |..|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

SDYG----------QPFIDRTTN---------------PGNPVYSAPEAANPR----------------EHSPAMDVFSYGVLLVEMVSRRIPLPDER--
.|.|          .  .  |..                |.| . |||. .                  | |...||.|.|..| |...|..|  |.   
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------RALIDGIRR--------------------ASFRSLVQCCLIVEYRQRPTMNDIITEL
               .|  .|                     |...| |.|   . ..||....|. .|
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK564.AA MLK 525-716 23 6.3e-26 87.01 In-house 1-235 (291) Show / Hide 
Range on Protein: 525-716
Range on HMM: 1-235/291
Sequence Identity: 23% (55 aa)

IMTGRVLGRGGWAEVRVASFHGLE-----VAAKVLHDTIISEYNLS-----LFSRDINIASKIRHPN----LLQFIGATTE-GN-PIILTELMPT-SLRK
| . ...| |.  .|  . ... .     || |  . .|. .   .      | ..........|||      || |. .. ..   |..| ..  ||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELETG---------------GLAYHAVLDISLDVAFALNYLHLFKPHPILHRDVSSANVLLQS----IGHGWRAKLSDYGQPF----I-D-RTTNPGNPV
 | ..                   . .....|..| ...|||  .|.|| |||  | |.|.      ..||  .| .| |  .    . . .. |.|.. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHG-TLKICDFGTSRDWHQMCTNMMSNAGTYA

YSAPEA---ANPREHSPAMDVFSYGVLLVEMVSRRIP
. |||.   .     | . ||.|.||.| ||..|..|
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK564.AA TK 525-758 12 4.7e-22 70.04 In-house 1-486 (486) Show / Hide 
Range on Protein: 525-758
Range on HMM: 1-486/486
Sequence Identity: 12% (63 aa)

IMTGRVLGRGG---WAEVRVASFHGL---------------------------EVAAKVLHDTIISEYN-LSL--------------FSRDINIAS--KI
|  |..||.|    . ||. .  .|.                           .|| |.|...  .. .   .              . . . . .  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNLLQFIGATTEGN-------------PIILTELMP-TS----LRKELETGG----------------------------------------------
.|||.....|. |.|              ..|..|.||  .    ||. | .                                                
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LAYHAVLDISLDVAFALNYLHLFKPHPI----LHRDVSSANVLLQSIGH--------GWRAKLSDYG--
                               |  |  | .....| .. |||  .         |||.   |.|. . ..        |  .|..|.|  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

-------------QPFIDRTTNPGNPV-------------------------YSAPEAAN---------PREHSPAMDVFSYGVLLVEMVS--RRIPLP-
                  |....| ..                         . |||. |          . .... ||.|.|||. |...  .  . . 
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

-------------DERRALIDG--------------IRRA--------------------SFRSL-VQCCLIVEYRQRPTMNDIITEL
             .  . | .|               |..                     .  .  |.|   . ..|||. ..  .|
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK564.AA S_TKc 525-762 20 9.9e-22 79.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 525-762
Range on HMM: 1-231/231
Sequence Identity: 20% (53 aa)

IMTGRVLGRGGWAEVRVASFHG--LEVAAKVLHDTIISEYNLSLFSRDINIASKIRHPNLLQFIGATTEGNPIILTELMPT---SLRKELETGG------
   .|..|.|. ..|. .  ..   .|| |...           . | |.| .| .|||. .....  ...  . .|....   .|.. ..  |      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LAYHAVLDISLDVAFALNYLHLFKPHPILHRDVSSANVLLQSIGHGWRAKLSDYGQPFIDRTTNPGNPVYSAPEAANPREHSP-AMDVFSYGVLLVEMV
 .    .  .   .. ||.|.|  .   |.|||.  .|.|| .     . |..| |   .  ||  | | | |||      ... . |. | |..| ||.
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-----HIKICDFGLARQL-TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SRRIPLPDERRALIDGIRRASFRSLVQCCLIVEYRQRPTMNDIIT-----ELKETI
... | | .  .... |.  ....... || .. ..|||  .. .      . . .
CGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK564.AA TKL-Unique 527-716 25 3.7e-21 71.5 In-house 1-233 (290) Show / Hide 
Range on Protein: 527-716
Range on HMM: 1-233/290
Sequence Identity: 25% (59 aa)

TGRVLGRGGWAEVRVASFHGLEVAAKVLH-DTIISEYNLSLFSRDINIASKIR-HPNLLQFIGATT-----EGNPIILTELMPT-SLRKELE--------
 . ..|.|| ..|  . ..| .|| |..|    .|   .  |.. .|. .|.. |||.....|...     ..| .| .| .|  ||.. |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

---TGGLAYHAVLDISLDVAFALNYLHLFKPHPILHRDVSSANVLLQSI--GHGWRAKLSDYG----QPFIDRTTNP-----------GNPVYSAPEAAN
      | .  .... .|.| ...|||  .|  |.|||  | |.|. .      |..|..| |    .  |...||            |.. ..|||  .
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

P--REHSPAMDVFSYGVLLVEMVSRRI------P
      |   ||.|.|. | |...| |      |
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase AqueK564.AA CZAK 525-711 31 3.9e-21 73.59 In-house 1-216 (279) Show / Hide 
Range on Protein: 525-711
Range on HMM: 1-216/279
Sequence Identity: 31% (69 aa)

IMTGRVLGRGGWAEVRVASFHGLEVAAKVLHD----TIISEYNLSLFSRDINIASKIRHPNLLQFIGATTEGN---PIILTELMP-TSLRKELETGGLAY
   |.. |.|   ||. |   |  || | .|     .  .   .  | . . | || .||| .||.|| .|..     | .| |   |||. | |    |
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLL-TDHYFY

HAV-----LDISLDVAFALNYLHL-FKPHPILHRDVSSANVLL-QSIG---------HGWRAKLSDYG-------QPFIDRTTNPGNPVYSAPEAANPRE
|       . . .|.|   ||||  .|| |||||| || |.|| .|.              .| .|.|       ||| . |   |   . |||      
HKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPF-EMTQTMGCLCWMAPECFKGEN

HSPAMDVFSYGVLLVEMV
 ..  ||.|.| .| ...
YTEKVDVYSFGMILWCII
Kinase AqueK564.AA Dicty4 525-602 37 1.1e-16 52.27 In-house 1-85 (277) Show / Hide 
Range on Protein: 525-602
Range on HMM: 1-85/277
Sequence Identity: 37% (32 aa)

IMTGRVLGRGGWAEVRVASFHGLEVAAKVL--HDTIISEYNLSLFSRDINIASKIRHPNLLQFIGATT-----EGNPIILTELMP
| ..  .|.|. .||  ..  | ||| |.|  | .  .|. |. | . ..| .||||||...| || |      | . | ||.||
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMP
Kinase AqueK564.AA HH498 620-716 39 3.3e-16 47.49 In-house 124-225 (284) Show / Hide 
Range on Protein: 620-716
Range on HMM: 124-225/284
Sequence Identity: 39% (41 aa)

LDISLDVAFALNYLHLFKPHPILHRDVSSANVLLQSIGHGWRAKLSDYG-----QPFIDRT-TN-PGNPVYSAPEAAN-PREHSPAMDVFSYGVLLVEMV
. ||.|||   ||||   .||| |||  | |.|.   ||   |.  |.|     .   | . |  |||. . |||        |   |||||.  . || 
MTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGH---AVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEMH

SRRIP
.|..|
TREVP
Kinase AqueK564.AA DRK 525-668 34 4.5e-16 50.96 In-house 1-145 (258) Show / Hide 
Range on Protein: 525-668
Range on HMM: 1-145/258
Sequence Identity: 34% (51 aa)

IMTGRVLGRGGWAEVRVASFHGLEVAAKVLHDTIIS-EYNLSLFSRDINIASKIRHPNLLQFIGATTE-GNPIILTELMPT-SLRKEL--ETGGLAYHAV
|  |   |||...||   .  | .|| | |    |  |  |. | | ||. .. ||||  ||.|. ..   . | .| ||  || . |  |   .    .
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

LDISLDVAFALNYLHLFKPHPILHRDVSSANVLLQSIGHGWRAKLSDYG
. . .|.|  ..|||   |  |.|||  | | |   .   |. | .|.|
KQMMFDCAKGMIYLHCCNPI-IIHRDLKSHNLL---VDEHWQVKVADFG
Kinase AqueK564.AA TyrKc 525-758 20 3e-14 7.6 SMART 1-280 (280) Show / Hide 
Range on Protein: 525-758
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

IMTGRVLGRGGWAEVRVASFHGLEVAAKVLHDTIISEYNLSLFSRDINIASKI--RHPNLLQFIGATTE--------GNPIILTELMPT-SLRKELETGG
|  |..||.|   ||. .    ..|| |.|..       .  | | ..| .|.  .|||.....|. |.        . . |..|.||  .|.. |   .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LAYHAVLDISLDVAFALNYLHLFKPHPILHRDVSSANVLLQSIGHGWRAKLSDYG---QPFID-------RTTNP-----GN---PV-YSAPEAANPR
  |     |......|   .|||    ... |||    |.|. . .   ..| || |       |        .  .     |.   |.   |||. | .
PKLCMKDLLSFCWQIACGMEYLHS---KNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

EHSPAMDVFSYGVLLVEMVSRRIPLPDE-----------RRALIDGIRRASFRS---------------LVQCCLIVEYRQRPTMNDIITEL
. ... ||.|.||.. |. ..  . . .           .. . .| |.    .               . ..|   .  .|||...|. ..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK564.AA LRRK 525-716 20 4.2e-13 42.7 In-house 1-282 (351) Show / Hide 
Range on Protein: 525-716
Range on HMM: 1-282/351
Sequence Identity: 20% (59 aa)

IMTGRVLGRGGWA-EVRVASFHG----------------------------LEVAAKVLHDT--------------------------------IISEYN
.. .. .|||| . .|  | . |                             .||.|... .                                . .  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LSLFSRDINIASKIRHPNLLQFIGATTEGNPIIL-TELMPT-SLRKELE---TGG-------LAYHAVLDISLDVAFALNYLHLFKPHPILHRDVSSANV
...| . . | |. .|||... .| .   .|... .|..|  .| . |.     |       .  . .| |.|..| ...||| ..| ||.|||  | |.
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNI

LLQSIG---------HGWRAKLSDYGQPF----IDRT---TNPGNPVYSAPEAANPR---EHSPAMDVFSYGVLLVEMVSRR-IP
||.|.              ||..|.|.      .  .   .  |||.. |||  .     | .   |..|.|..| | ..|. .|
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase AqueK564.AA Pkinase_Tyr 525-668 23 3.3e-12 41.98 Pfam 1-156 (270) Show / Hide 
Range on Protein: 525-668
Range on HMM: 1-156/270
Sequence Identity: 23% (39 aa)

IMTGRVLGRGGWAEVRVASFH------GLEVAAKVLHDTIISEY--NLSLFSRDINIASKI-RHPNLLQFIGATT-EGNP---IILTELMPT-SLRKELE
|  |..||.|   ||. .  .      ...|| |.| ..  .|     ....  ..| ... .|||.....|. | .| |   .| .|.||  .|.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

TG-----GLAYHAVLDISLDVAFALNYLHLFKPHPILHRDVSSANVLLQSIGHGWRAKLSDYG
.       |  .  |......| ...||.  .   . |||.   |.|. .   .  .| .| |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE--NN-VVKICDFG
Kinase AqueK564.AA Pkinase 681-762 17 1.4e-10 38.48 Pfam 175-293 (293) Show / Hide 
Range on Protein: 681-762
Range on HMM: 175-293/293
Sequence Identity: 17% (22 aa)

PVYSAPEAAN-PREHSPAMDVFSYGVLLVEMVSRRIPLPDE-------RRALIDGIRR-------------------------------ASFRSLVQCCL
| | |||  .  ....|. |..|.|..| ||...| | |..        ...|. |..                                ...... .||
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

IVEYRQRPTMNDIITELKET--I
 .   .|||    ......   .
CKDPKKRPT----AEQILQHPWF
Kinase AqueK564.AA LISK 530-588 23 5.7e-10 28.38 In-house 1-64 (296) Show / Hide 
Range on Protein: 530-588
Range on HMM: 1-64/296
Sequence Identity: 23% (15 aa)

VLGRGGWAEVRVASFH--GLEVAAKVLH---DTIISEYNLSLFSRDINIASKIRHPNLLQFIGA
..|.|. ..|   .    | ..| | .|   .. . . ..  . | . .  ..|||| .||.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV
Kinase AqueK564.AA Pkinase 525-653 18 1.6e-08 31.19 Pfam 1-141 (293) Show / Hide 
Range on Protein: 525-653
Range on HMM: 1-141/293
Sequence Identity: 18% (27 aa)

IMTGRVLGRGGWAEVRVASFHGLE--VAAKVLH-DTIISEYNLSLFS-RDINIASKIRHPNLLQFIGAT-TEGNPIILTELMPT-----SLRKELE---T
. .||..|.|. ..|. .  .| .  || |..  ... |. . ...  . | |  ...||| ......  ..... . .|...      .|   ..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GGL--AYHAVLDISLDVAFALNYLHLFKPHPILHRDVSSANVLL
|..   .. . .. . .. .|.|.|      |.|||. ..|.|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILI
Kinase AqueK564.AA LISK 699-719 47 3e-06 16.13 In-house 221-241 (296) Show / Hide 
Range on Protein: 699-719
Range on HMM: 221-241/296
Sequence Identity: 47% (10 aa)

DVFSYGVLLVEMVSRRIPLPD
||||.|..|.|.. |. . ||
DVFSFGIVLCEIITRVKADPD
Kinase AqueK564.AA LISK 620-668 38 3.7e-05 12.47 In-house 104-150 (296) Show / Hide 
Range on Protein: 620-668
Range on HMM: 104-150/296
Sequence Identity: 38% (19 aa)

LDISLDVAFALNYLHLFKPHPILHRDVSSANVLLQSI-GHGWRAKLSDYG
..|.||.| .. |||  .   |.|||  | |.|.  .   .||.|. | |
VKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFG
Kinase AqueK564.AA Dicty4 699-760 21 0.002186 7.35 In-house 199-277 (277) Show / Hide 
Range on Protein: 699-760
Range on HMM: 199-277/277
Sequence Identity: 21% (17 aa)

DVFSYGVLLVEMVSRRIPLP---DERRALIDGIRR------------ASFRSLVQCCLIVEYRQRPTMNDIITE--LKE
||.|.| .| |.. | .| .   ..   ..... .            .|...|.| |.  .  .||... || .  | .
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK564.AA TKL-Unique 747-758 50 0.008611 5.89 In-house 279-290 (290) Show / Hide 
Range on Protein: 747-758
Range on HMM: 279-290/290
Sequence Identity: 50% (6 aa)

QRPTMNDIITEL
|||. ..||..|
QRPSFDEIIHRL
Kinase AqueK564.AA LRRK 746-760 26 0.009224 5.58 In-house 337-351 (351) Show / Hide 
Range on Protein: 746-760
Range on HMM: 337-351/351
Sequence Identity: 26% (4 aa)

RQRPTMNDIITELKE
..||....|.  |..
KKRPHFSQIVKRLSQ
Kinase AqueK564.AA DRK 699-716 44 0.009954 5.11 In-house 184-201 (258) Show / Hide 
Range on Protein: 699-716
Range on HMM: 184-201/258
Sequence Identity: 44% (8 aa)

DVFSYGVLLVEMVSRRIP
||.|... | |.| | .|
DVYSFAIVLWECVTRQDP
Kinase AqueK564.AA MLK 731-758 21 0.042539 3.23 In-house 264-291 (291) Show / Hide 
Range on Protein: 731-758
Range on HMM: 264-291/291
Sequence Identity: 21% (6 aa)

ASFRSLVQCCLIVEYRQRPTMNDIITEL
... .| ..|   . ..||..  |...|
EHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK564.AA Pkinase_Tyr 685-713 37 0.364063 4.57 Pfam 182-210 (270) Show / Hide 
Range on Protein: 685-713
Range on HMM: 182-210/270
Sequence Identity: 37% (11 aa)

APEAANPREHSPAMDVFSYGVLLVEMVSR
|||. | .. . . || |.|||. |....
APECINYGKFTTKSDVWSFGVLMWEIFTY
Kinase AqueK564.AA Pkinase_Tyr 747-758 41 1.289308 2.71 Pfam 259-270 (270) Show / Hide 
Range on Protein: 747-758
Range on HMM: 259-270/270
Sequence Identity: 41% (5 aa)

QRPTMNDIITEL
.|||. .|. .|
DRPTFSEIHEQL