Gene AqueK567 (A.queenslandica)

AqueK567

Species: A.queenslandica
Alias: AqueK567
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-B

Sequence

Name Sequence Type Origin Length Description Download
AqueK567.AA Protein None 940 None Fasta, JSON
AqueK567.kin_dom Protein Kinase Domain None 240 None Fasta, JSON

Protein domain

Protein domains of AqueK567.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK567.AA Kelch_2 176-232 17 0.010786 14.36 Pfam 1-51 (51) Show / Hide 
Range on Protein: 176-232
Range on HMM: 1-51/51
Sequence Identity: 17% (10 aa)

ERNSHSTVRVGDYLYMWGGTQPDPPRVHNNEKKKSMYSVMEVCHLRTGRWEQKPTTG
 | .|... .|. .|..||         ..  . .  ... .....| ||.  |  .
PRYCHASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK567.AA Kelch_1 176-232 15 1.610528 5.63 Pfam 1-45 (45) Show / Hide 
Range on Protein: 176-232
Range on HMM: 1-45/45
Sequence Identity: 15% (9 aa)

ERNSHSTVRVGDYLYMWGGTQPDPPRVHNNEKKKSMYSVMEVCHLRTGRWEQKPTTG
 | .|. . .....|  ||  .            .  .  |. ...|..|.. |. .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK567.AA Kelch_1 237-281 22 0.008477 13.8 Pfam 1-45 (45) Show / Hide 
Range on Protein: 237-281
Range on HMM: 1-45/45
Sequence Identity: 22% (10 aa)

GVRGYAAATIGREIFYFGGYRDSYHNSLCSFEVDTFNWKELSPTT
  .|....... .|. .||. ..| ||  .. ..|  |....| .
PRCGHGVCVHNGKIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK567.AA Kelch_2 237-281 19 0.205102 9.5 Pfam 1-51 (51) Show / Hide 
Range on Protein: 237-281
Range on HMM: 1-51/51
Sequence Identity: 19% (10 aa)

GVRGYAAATIGREIFYFGGY------RDSYHNSLCSFEVDTFNWKELSPTT
.  . |....|  |. ||||       |......  .  .|  |.....  
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_2 AqueK567.AA Kelch_2 299-351 15 0.101548 10.66 Pfam 8-51 (51) Show / Hide 
Range on Protein: 299-351
Range on HMM: 8-51/51
Sequence Identity: 15% (8 aa)

VNGEDYLVVIGGYGSTSNNSPKQPGAQYSDQRCNEIHFYKLSTGQWISPTVTG
. ... ..|.|||          ....  | ... |... ..| .|   .. .
CVPGGKIYVFGGYC---------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK567.AA Kelch_1 302-344 23 4.44226 4.05 Pfam 11-38 (45) Show / Hide 
Range on Protein: 302-344
Range on HMM: 11-38/45
Sequence Identity: 23% (10 aa)

EDYLVVIGGYGSTSNNSPKQPGAQYSDQRCNEIHFYKLSTGQW
.... ||||. .               |. | .  | ..|.||
NGKIYVIGGCDG---------------QYLNSVECYDPETNQW
Kelch_2 AqueK567.AA Kelch_2 412-457 20 0.000244 20.61 Pfam 1-51 (51) Show / Hide 
Range on Protein: 412-457
Range on HMM: 1-51/51
Sequence Identity: 20% (11 aa)

ERRSHSSVLINTSSGPHLLVVGGC---------LTDDSWIFNINNKSWKELKDIP
 | .|.|. .    |  ..|.||.          . | |... . ..|......|
PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK567.AA Kelch_1 423-457 15 0.201051 8.87 Pfam 8-45 (45) Show / Hide 
Range on Protein: 423-457
Range on HMM: 8-45/45
Sequence Identity: 15% (6 aa)

TSSGPHLLVVGGCL---TDDSWIFNINNKSWKELKDIP
.. . .. |.|||    ... ....  ...|... . |
CVHNGKIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP
Kinase AqueK567.AA TKL 703-936 18 1.8e-46 160.72 In-house 1-364 (364) Show / Hide 
Range on Protein: 703-936
Range on HMM: 1-364/364
Sequence Identity: 18% (68 aa)

LGEGGWGEVKVADFRG----------LKVAAKSLQKLIISPYNI-------------------------GTFSCEMNIASKIRHPNLLQFIGATTEGN--
.|.|| |||  . .||            || | . .   .  ..                          ..  |... |..||||..||.|. ....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PMILTELM-PTSLRKELESGGVAYPAILSISLDVACALNYLHLFKP-----HPILHRDVSSANVLLQPMGG--------YGYCWKAKV
            ..| .|..   ||.  |       . .....||.|...||||  .|      ||.|||  |.|.|.   .           . |..|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

SDYGTVNLQPLS---------------------RTSNPG-NPVYLAPESFNPN----------------QHSPAMDVFSYGVLLIEMVVCE--FPDVGKR
.|.|.      |                     .|.... .| ..||| .. .                . |...||.|.|..| |.. ..  . | . .
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------VAQIKAIKRPTLK--------------------NLIERCLIENYKDRPTMSDIIKEL
            .  ..  .||...                    .|...|  .. ..||....|.|.|
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK567.AA CZAK 700-894 31 9e-26 90.65 In-house 4-221 (279) Show / Hide 
Range on Protein: 700-894
Range on HMM: 4-221/279
Sequence Identity: 31% (69 aa)

EVVLGEGGWGEVKVADFRGLKVAAKSLQKLIISPYNIGT-----FSCEMNIASKIRHPNLLQFIGATTEGN---PMILTELMP-TSLRKELE--SGGVAY
. . |.|  |||. |  ||  || | .  ..      ..     |  |  | || .||| .||.|| .|..     | .| |   |||. |   .  .  
GQTIGQGFFGEVYKAYWRGKDVAIKIIH-RNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYHKQ

-PAI-LSISLDVACALNYLHL-FKPHPILHRDVSSANVLLQPMGG-------YGYCWKAKVSDYGTV---NLQPLSRTSNPGNPVYLAPESFNPNQHSPA
 | . ... .|.|   ||||  .|| |||||| || |.||                 ..|..|.|       ||   |.  |   . ||| |     .. 
NPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEK

MDVFSYGVLLIEMVVCEFP
 ||.|.| .| ... |. |
VDVYSFGMILWCIITCDQP
Kinase AqueK567.AA TK 742-936 13 3.4e-23 73.92 In-house 88-486 (486) Show / Hide 
Range on Protein: 742-936
Range on HMM: 88-486/486
Sequence Identity: 13% (55 aa)

EMNIASKIR-----HPNLLQFIGATTEGN-------------PMILTELMP-TS----LRKELESGG---------------------------------
|...... .     |||.....|. |.|              .||..|.||  .    ||. | .                                   
EAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYS

--------------------------------------------VAYPAILSISLDVACALNYLHLFKPHPI----LHRDVSSANVLLQPMGGY-----G
                                            .  .  | .....||.. |||  .         |||.   |.|.   .       |
HESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDG

YCWKAKVSDYG---------TVNLQPL---SRTSNPGNPV-------------------------YLAPESFN---------PNQHSPAMDVFSYGVLLI
..  .|..|.|         .  ...     |.|..| ..                         ..|||..|          . .... ||.|.|||. 
CGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMW

EMVV-C-EFPDVGKR-------------VAQIKAI-----------------KRPTLKN-------------------LIERCLIENYKDRPTMSDIIKE
|..  . | .  |               . ....                  ..| .                     |. .|  .. .||||.|.. ..
EIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQ

L
|
L
Kinase AqueK567.AA S_TKc 697-940 20 7.4e-23 83.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 697-940
Range on HMM: 1-231/231
Sequence Identity: 20% (55 aa)

TMTEVVLGEGGWGEVKVADFRG--LKVAAKSLQKLIISPYNIGTFSCEMNIASKIRHPNLLQFIGATTEGNPMILTELMPT---SLRKELESGG------
     ..|.|. |.|. .  ..   .|| | .           ..  |..| .| .|||. .....  ...  . .|....   .|.. ... |      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-VAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGYGYCWKAKVSDYGTVNLQPLSRTSNPGNPVYLAPESFNPNQHSP-AMDVFSYGV
      . ..   ..|||.|.|  .   |.|||.  .|.||            |..| |   .     |.  | | |.||| .   .... . |. | |.
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--------HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LLIEMVVCEFPDVGKRVAQIKAIKRPTLKNLIERCLIENYKDRPTMSDIIK-----ELNESI
.|.||.. . |      . .| |. | .|..|..||  . ..|||  .. .      . . .
ILYEMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK567.AA MLK 697-894 24 9.1e-23 75.89 In-house 1-235 (291) Show / Hide 
Range on Protein: 697-894
Range on HMM: 1-235/291
Sequence Identity: 24% (58 aa)

TMTEVVLGEGGWGEVKVADFRGLK-----VAAKSLQKLIISPYN----IGTFSCEMNIASKIRHPN----LLQFIGATTE-GN-PMILTELMPT-SLRKE
  .. ..|.|. |.|  . .|.       || |     |..       .  |  | .......|||      || |. .. ..   |..| ..  ||   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LESG---------------GVAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQ----PMGGYGYCWKAKVSDYGTVN-LQPL-S-RTSNPGN
| ..                .    .....|..| ...|||  .|.|| |||  | |.|.     .|..     ..|..| ||.  ..   . ..||.|.
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHG----TLKICDFGTSRDWHQMCTNMMSNAGT

PVYLAPESF---NPNQHSPAMDVFSYGVLLIEMVVCEFP
. . ||| .     .. | . ||.|.||.| ||. .| |
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK567.AA TKL-Unique 702-889 25 7.4e-21 70.4 In-house 4-222 (290) Show / Hide 
Range on Protein: 702-889
Range on HMM: 4-222/290
Sequence Identity: 25% (57 aa)

VLGEGGWGEVKVADFRGLKVAAKSLQK-LIISPYNIGTFSCEMNIASKIR-HPNLLQFIGATT-----EGNPMILTELMPT-SLRKELE-----------
..|||| |.|. . .|| .|| |.. .   .|.  . .|. | |. .|.. |||.....|...     ..|  | .| .|  ||.. |            
KIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNN

SGGVAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGYGYC-----WKAKVSDYGTVNLQP-LSRTSNP-----------GNPVYLAPE
.    .  .... .|.| ...|||  .|  |.|||  | |.|.              |..|..| |.. ..   ....|            |.. ..|||
NCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVD------NNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

SFNP--NQHSPAMDVFSYGVLLIEMV
 ..   .| |   ||.|.|. |.|..
VLRMNFCQYSEKSDVYSFGIVLWEIA
Kinase AqueK567.AA STE 698-934 16 2e-18 61.74 In-house 1-353 (359) Show / Hide 
Range on Protein: 698-934
Range on HMM: 1-353/359
Sequence Identity: 16% (62 aa)

MTE-VVLGEGGWGEVKVA---D-----FRGLK---------VAAKSLQK---------------LIISPYNIGTFSCEMNIASKIR--HPNLLQFIGATT
 .   ..|.|. |.|  |   .       | .         .| | . .                .. . ..  .  |..| .| .  |||  ...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

--------EGNPMILTELMP-TSLRKELESGGVAY---------------PAILSISLDVACA-LNYLHLFKPHPILHRDVSSANVLLQPMGGYGYCWKA
        ...  |  |.|.  ||.. ... .                  . |  |  ..  . |.|||  .   | |||. .||.||           .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----------V

KVSDYGTVN-LQP------------------LSRTSNPGNPVYLAPESFNP------NQHSPAMDVFSYGVLLIEMVVCEFP----DVGKRVAQIKAI--
| .| |.   |..                    |..  | | . |||  ..      ....   |. | | ..|||.  . |       .   .|     
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

------------------KR----------------------PTLKNLIERCLIENYKDRPTMSDIIK
                  .                       | .|. |..||. ....||| |. .|
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLK
Kinase AqueK567.AA Dicty5 734-888 28 1.1e-17 57.45 In-house 38-196 (260) Show / Hide 
Range on Protein: 734-888
Range on HMM: 38-196/260
Sequence Identity: 28% (48 aa)

YNIGTFSCEMNIASKIR--HPNLLQFIGATTEGNPM--ILTELMPT-SLRKELESGGV------AYPAILSISLDVACALNYLHLFKPHPILHRDVSSAN
...  |  |  | | .   |||.  . || .       ..||.    ||.  |           ||. .|.. .|.| .. .||      | |||. | |
FDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMN---IIHRDLKSMN

VLLQPMGGYGYCWKAKVSDYGT---VNLQPLSRTSNPGNPVYLAPESFNPNQHSPAMDVFSYGVLLIEM
.|.         ||.|. |.||   | .. .  | . | . . |.| || .      ||.|.|. | ||
FLITEN------WKIKIIDFGTSRFVDNR-YHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEM
Kinase AqueK567.AA Dicty4 699-824 31 4.9e-16 50.15 In-house 3-146 (277) Show / Hide 
Range on Protein: 699-824
Range on HMM: 3-146/277
Sequence Identity: 31% (46 aa)

TEVVLGEGGWGEVKVADFRGLKVAAKSL--QKLIISPYNIGTFSCEMNIASKIRHPNLLQFIGATT-----EGNPMILTELM-PTSLRKELES------G
.|. .|.|. |||  .  || .|| | |   .   . . .  |  | .| .||||||...| || |      | ..| ||.|  ..| . | .       
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

GVAYP--AILS---ISLDVACALNYLHLFKPHPILHRDVSSANVL
 .  .   |..   . .|.|  .|.||   |  |.|||  |.| |
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLL
Kinase AqueK567.AA TyrKc 696-936 23 6.8e-16 34.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 696-936
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

ITMTEVVLGEGGWGEVKVADFRGLKVAAKSLQKLIISPYNIGTFSCEMNIASKI--RHPNLLQFIGATTE--------GNPMILTELMPT-SLRKELESG
||. . .||||  |||  .  . ..|| |.|..       .  |  |..| .|.  .|||.....|. |.        . .||..|.||  .|.. | . 
ITLGK-KLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

G--VAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGYGYCWKAKVSDYG-TVNLQPL-------SRTSN----PGN---PV-YLAPES
.  .  .  ||.....||  .|||    ... |||    |.|.   .       .|.|| | . ..          .  .      |.   |.  .|||.
RPKLCMKDLLSFCWQIACGMEYLHS---KNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

FNPNQHSPAMDVFSYGVLLIEMV-------------------VCEFPDVGKRVAQIKA-------IKRPTLKNLIERCLIENYKDRPTMSDIIKEL
.| .  ... ||.|.||.. |.                    | |. . |.|  | .        .  . . .....|  |. .||||.|.|....
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK567.AA Pkinase 742-940 18 1.6e-15 56.01 Pfam 50-293 (293) Show / Hide 
Range on Protein: 742-940
Range on HMM: 50-293/293
Sequence Identity: 18% (47 aa)

EMNIASKIRHPNLLQFIGAT-TEGNPMILTELMPT-----SLRKELE---SGGV--AYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGG
|  |  ...||| ......  ..... . .|...      .|   ..   .|..   .  . .. . ....|.|.|      |.|||. ..|.|.   | 
EIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGH

YGYCWKAKVSDYGTVN---LQPLSRTSNPGNPVYLAPESFN-PNQHSPAMDVFSYGVLLIEMVVCEFPDVGK----------RVAQIKA-------IKR-
 .   . |..| |      . . | |.  | | |.|||  .  . ..|. |..|.|..|.||.  ..|  |.          ....|.         .  
IDA--CVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWC

--------------------PTLKNLIERCLIENYKDRPTMSDIIKELNES--I
                    ...| .|..||  . |.|||    .... ..  .
SISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase AqueK567.AA TK-Unique 696-889 20 1.7e-14 46.55 In-house 1-233 (294) Show / Hide 
Range on Protein: 696-889
Range on HMM: 1-233/294
Sequence Identity: 20% (49 aa)

ITMTEVVLGEGGWGEVKVADFRGLK---VAAKSLQKLIISPYNIGT----FSCEMNIASKIR-HPNLLQFIGATT-EG-NPMILTELMPTS-LRKELESG
... . |.|||  |.|  ....|..    . |.        .. .|    | .| .. ...  |||..|..|..|  . ..||. | .| . |.. | . 
LEV-GDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

G---------------------------VAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGGYGYCWKAKVSDYGTV------NLQPLS
.                           . .   ...  ..||...||.   .. | |||... ||||.         ..|..|.|        . .  .
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQ-RKKIVHRDLCARNVLLTE------DKVCKICDFGMARDVYTNGVYSMM

RTSNPGNPVYLAPESFN--PNQH-SPAMDVFSYGVLLIEMV
.....    ..||||.    ... ..  || |.|||. |..
CSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIF
Kinase AqueK567.AA Pkinase_Tyr 696-825 26 5.9e-12 41.11 Pfam 1-144 (270) Show / Hide 
Range on Protein: 696-825
Range on HMM: 1-144/270
Sequence Identity: 26% (39 aa)

ITMTEVVLGEGGWGEVKVADFR------GLKVAAKSLQKLIISPYN--IGTFSCEMNIASKI-RHPNLLQFIGATT-EGNP---MILTELMPT-SLRKEL
||. .. ||||  |||. .  .      ...|| |.| |   .. .  .  |  |..| ... .|||.....|. | .| |   .| .|.||  .|.. |
ITFGKK-LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

ESG-----GVAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLL
 .       .  . .|......|....||.  .   . |||.   |.|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLV
Kinase AqueK567.AA LRRK 697-885 21 8.1e-12 38.07 In-house 1-272 (351) Show / Hide 
Range on Protein: 697-885
Range on HMM: 1-272/351
Sequence Identity: 21% (58 aa)

TMTEVVLGEGGWG-EVKVADFRG----------------------------LKVAAKSLQK--------------------------------LIISPYN
 . |  .|.|| | .|  |..||                             .||.|.. .                                .. .. .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

IGTFSCEMNIASKIRHPNLLQFIGATTEGNPMIL-TELMPT-SLRKELE---SGG------V-AYPAILSISLDVACALNYLHLFKPHPILHRDVSSANV
  .|  |. | |. .|||... .| .   .|... .|..|  .| . |.   . |      .     .| |.|..| ...||| ..| ||.|||  | |.
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNI

LLQPMG-GY-----GYCWKAKVSDYGTVN----LQP-LSRTSNPGNPVYLAPESFNPN---QHSPAMDVFSYGVLL
||. .  ..     .   .||..|.|.      ... . ...  |||...|||  . |   . .   |..|.|..|
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV-GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Kinase AqueK567.AA Dicty4 909-938 31 1.3e-07 21.7 In-house 246-277 (277) Show / Hide 
Range on Protein: 909-938
Range on HMM: 246-277/277
Sequence Identity: 31% (10 aa)

PTLKNLIERCLIENYKDRPTMSDIIKE--LNE
| .| ||..|. .. . ||... ||..  |..
PSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK567.AA LRRK 909-938 33 6e-06 17.03 In-house 322-351 (351) Show / Hide 
Range on Protein: 909-938
Range on HMM: 322-351/351
Sequence Identity: 33% (10 aa)

PTLKNLIERCLIENYKDRPTMSDIIKELNE
. ...||. |  .. |.||..|.|.| | .
HMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK567.AA MLK 909-936 25 8e-06 16.27 In-house 264-291 (291) Show / Hide 
Range on Protein: 909-936
Range on HMM: 264-291/291
Sequence Identity: 25% (7 aa)

PTLKNLIERCLIENYKDRPTMSDIIKEL
. .|.|...|  .. ..||... |...|
EHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK567.AA TKL-Unique 911-936 30 9e-06 16.61 In-house 265-290 (290) Show / Hide 
Range on Protein: 911-936
Range on HMM: 265-290/290
Sequence Identity: 30% (8 aa)

LKNLIERCLIENYKDRPTMSDIIKEL
...||..|   .  .||. ..||..|
YRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK567.AA TK-Unique 908-936 24 0.000133 11.93 In-house 266-294 (294) Show / Hide 
Range on Protein: 908-936
Range on HMM: 266-294/294
Sequence Identity: 24% (7 aa)

RPTLKNLIERCLIENYKDRPTMSDIIKEL
.... ||...|. .. ..||. ..|...|
SHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK567.AA Pkinase_Tyr 909-936 32 0.001238 12.93 Pfam 243-270 (270) Show / Hide 
Range on Protein: 909-936
Range on HMM: 243-270/270
Sequence Identity: 32% (9 aa)

PTLKNLIERCLIENYKDRPTMSDIIKEL
. . .|. .|  .. .||||.|.|. .|
DEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK567.AA Dicty5 913-940 32 0.022888 3.95 In-house 233-260 (260) Show / Hide 
Range on Protein: 913-940
Range on HMM: 233-260/260
Sequence Identity: 32% (9 aa)

NLIERCLIENYKDRPTMSDIIKELNESI
|||. |  .  . ||.   |.| ..  |
NLIKKCWQQKPHNRPSFKEICKYFESII
Kinase AqueK567.AA Pkinase_Tyr 862-889 39 0.25739 5.08 Pfam 181-208 (270) Show / Hide 
Range on Protein: 862-889
Range on HMM: 181-208/270
Sequence Identity: 39% (11 aa)

LAPESFNPNQHSPAMDVFSYGVLLIEMV
.|||..| .  . . || |.|||. |..
MAPECINYGKFTTKSDVWSFGVLMWEIF
Kinase AqueK567.AA CZAK 911-936 38 0.280333 0.59 In-house 254-279 (279) Show / Hide 
Range on Protein: 911-936
Range on HMM: 254-279/279
Sequence Identity: 38% (10 aa)

LKNLIERCLIENYKDRPTMSDIIKEL
|  |||.|   |   ||. . |.  |
LGELIEMCWNKNPDERPSFKQILQHL