Gene AqueK659 (A.queenslandica)

AqueK659

Species: A.queenslandica
Alias: AqueK659
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLK

Sequence

Name Sequence Type Origin Length Description Download
AqueK659.AA Protein None 581 None Fasta, JSON
AqueK659.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of AqueK659.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 AqueK659.AA SH3 104-165 30 5.2e-13 50.46 SMART 1-58 (58) Show / Hide 
Range on Protein: 104-165
Range on HMM: 1-58/58
Sequence Identity: 30% (19 aa)

NIGIVIGDFKGLYPDEITLTVGERIEILSKDMIVSRNIGWWAGRNS-KGTVGIFPAASVKVVS
   ... |...  |||.... |. |..|.||     . ||| ||.  .| .|.||.  |... 
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-----DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 AqueK659.AA SH3_2 105-164 20 3.5e-12 45.54 Pfam 1-68 (68) Show / Hide 
Range on Protein: 105-164
Range on HMM: 1-68/68
Sequence Identity: 20% (15 aa)

IGIVIGDFKG-LYPDE-----ITLTVGERIEIL---SKDMIVSRNIGWWAG-RN-SKGTV--GIFPAASVKVV
 ..|. |...  |..|     .....|. |...   .|| .     .|| . .. ..|..  | ||   |...
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWD-----NWWWCWETIWGGRRMRGWFPSQWVEEC
SH3_1 AqueK659.AA SH3_1 107-158 28 1.3e-05 22.12 Pfam 1-49 (49) Show / Hide 
Range on Protein: 107-158
Range on HMM: 1-49/49
Sequence Identity: 28% (15 aa)

IVIGDFKGLYPDEITLTVGERIEILSKDMIVSRNIGWWAGRNSK-GTVGIFPA
... |...  |||.... |. |....|.       .|| ||.   | .|.||.
VALYDYQAQQPDELSFKKGDIIHVIEKSDD----WDWWKGRCNNTGQEGWFPS
Kinase AqueK659.AA MLK 187-446 47 5.3e-119 395.05 In-house 1-280 (280) Show / Hide 
Range on Protein: 187-446
Range on HMM: 1-280/280
Sequence Identity: 47% (134 aa)

IKLGDVIGLGGFGKVYRAQYKGEDVAVKVARHTTYDTMKAV----SDVLSEAEKFAHLAHENVCALIGVCLV-KDVCLVMEYAKGGPLSKILHERNITLT
.|. ..|| ||||||||||.||| |||| .|..  . | .      .|  ||  |. |.|.|. || ||||     ||||||..||.|....  . | . 
LKIKEIIGNGGFGKVYRAQWKGEEVAVKAHRQDPEQDMQQTDEQAEQVRQEARLFWMLKHPNIIALRGVCLEDPHLCLVMEYCRGGSLNRVCAGKRIPP-

VDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVN-----------------PADLKGNLIKITDFGLAREIENTTHLSGAGTYPWMAPEVI
 ... .|  || .||.|||.|   ..|||||||||||.  ..                    |..    ||||||||||  .|| .| |||| |||||||
-HVLVNWAVQIARGMNYLHNEAPVPIIHRDLKSSNILILEKICLCMDEEMFQYAYCLKCGHHDMCNKQLKITDFGLAREWHKTTRMSAAGTYAWMAPEVI

KSSEFSKKSDVWSFGVVLWEILTGEKPYSGLDMFVVAYGVGHGTLTLPIPEHCPLSLRDLMSCCWKREHSKRPSFTQVKEKL
|.| .|| |||||.||.||| |||| || | |   |||||   .||||||. ||     ||  ||. .  |||.|... ..|
KESTWSKGSDVWSYGVLLWELLTGEVPYRGIDPLAVAYGVAMNKLTLPIPSTCPEPWAKLMQDCWNQDPHKRPKFSEILQQL
Kinase AqueK659.AA MLK 187-446 36 4.1e-108 365.49 In-house 1-291 (291) Show / Hide 
Range on Protein: 187-446
Range on HMM: 1-291/291
Sequence Identity: 36% (108 aa)

IKLGDVIGLGGFGKVYRAQYKGED-----VAVKVARHTTYDTMKA----VSDVLSEAEKFAHLAHEN----VCALIGVCLV--KDVCLVMEYAKGGPLSK
|..  .|| |.||||........|     |||| .|....  .        |.  |......| |.|    .... ||||   ...|.||||. ||.|. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ILHERN-------------ITLTVDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITDFGLAREIENT-T-HLSGAGTY
.||...             .. ..| ...|. |. .||.||| .  . .|||||||.|||.   .   |...   ||.|||..|.. .. | . | ||||
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDE-ICH-DMHHGTLKICDFGTSRDWHQMCTNMMSNAGTY

PWMAPEVI---KSSEFSKKSDVWSFGVVLWEILTGEKPYS-GLDMFVVAYGVGHGTLTLPIPEHCPLSLRDLMSCCWKREHSKRPSFTQVKEKL
 |||||||   ... .|.|.||||.||||||.||.| ||. ..| . .|..|..  |..|||  || ..  ||..||. . .||||| |. ..|
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK659.AA TKL 193-446 26 3.8e-90 305.81 In-house 1-364 (364) Show / Hide 
Range on Protein: 193-446
Range on HMM: 1-364/364
Sequence Identity: 26% (99 aa)

IGLGGFGKVYRAQYKG----------EDVAVKVARHT------------------------TYDTMKAVSDVLSEAEKFAHLAHENVCALIGVCLVKD--
|| ||||.||.....|          .|||||. . .                          .....      |.     | |.|.. ..|.|.  .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VCLVMEYAKGGPLSKILHERNITLTVDIILDWSRQITEGMEYLHHEIT-----PSLIHRDLKSSNILLQYEVNP------ADLKGNLI
             |.||||..|| |  .||        . ...|...|  ||.||| ...     | .|||||||.|||.    ..      .  .   .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KITDFGLAREIENT---------------------THLSGAGTYPWMAPEVIKSS----------------EFSKKSDVWSFGVVLWEILTGEKPYSGLD
||.||||.|.....                     |. .  ||. ||||||.. .                |.|.|.||.|||.|||||||...||....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

MFVVA---------YGVGHGTLTLPIP------------EHCPLSLRDLMSCCWKREHSKRPSFTQVKEKL
.. .          ..|..  | .|||            ..|| |...|| .||. . .|||||......|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK659.AA TyrKc 187-446 31 3.3e-85 290.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 187-446
Range on HMM: 1-280/280
Sequence Identity: 31% (95 aa)

IKLGDVIGLGGFGKVYRAQYKGEDVAVKVARHTTYDTMKAVSDVLSEAEKFAHL--AHENVCALIGVCLV--------KDVCLVMEYAKGGPLSKILHER
|.||...| | ||.||....| ..||||. .. .      . | ..||.   .|   |.|. .|.|||.         . ...||||...| | . |...
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

NITLTVDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITDFGLAREIENT--------THL-----SGA--GTYPWMAP
  .|...  |... || .||||||.     .|||||   |.|.  .          .||.||||.|.|..         .       .|     . ||||
RPKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH--------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EVIKSSEFSKKSDVWSFGVVLWEILT-GEKPYSG-----LDMFVVAYGVGHGTLTLPIPEH--------CPLSLRDLMSCCWKREHSKRPSFTQVKEKL
|.|. ..|. |||||||||..|||.| |..||.|     .. . |   | .|   .|.|..        ||  . ..|..||... ..||.|....|..
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG-YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK659.AA Pkinase_Tyr 187-446 35 3.5e-81 275.55 Pfam 1-270 (270) Show / Hide 
Range on Protein: 187-446
Range on HMM: 1-270/270
Sequence Identity: 35% (101 aa)

IKLGDVIGLGGFGKVYRAQYK------GEDVAVKVARHTTYDTMKA---VSDVLSEAEKFAHL-AHENVCALIGVCL-VKD---VCLVMEYAKGGPLSKI
|..| ..| | ||.||.. .|      . .||||. ..   ..|.      | ..||.   .|  |.|.  |.|||.  ..   ...||||...| | . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LHER---NITLTVDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITDFGLAREI----EN-TTHLSGAGTYPWMAPEVI
|...   .  ||.  .|....|| .|||||.      .|||||   |.|.         ..| .||.|||||| |    .  ... .|    .|||||.|
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVT--------ENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECI

KSSEFSKKSDVWSFGVVLWEILT-GEKP-YSGLDMFVVAYGV-GHGTLTLPIPEHCPLSLRDLMSCCWKREHSKRPSFTQVKEKL
. ..|. |||||||||..|||.| ||.| | |.. . |   .  .|   .|.||.||  . |||  ||. . ..||.|... |.|
NYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR-MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK659.AA Pkinase 187-446 26 5.7e-77 266.81 Pfam 1-293 (293) Show / Hide 
Range on Protein: 187-446
Range on HMM: 1-293/293
Sequence Identity: 26% (81 aa)

IKLGDVIGLGGFGKVYRAQYKGED--VAVKVARHTTYDTMKAVSDVL-SEAEKFAHLAHENVCALIGVCL-VKDVCLVMEYAKGG----PLSKILH-ERN
...| .|| |.||.||... ||.   ||||. .  . .  | ..... ||..  ..| |.|.. |....   .....||||. ||     |. ... .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ITL--TVDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITDFGLAR---EIENTTHLSGAGTYPWMAPEVIK-SSEFSK
 ..  . . . .. .|| .|.||.| .   . ||||||..|||.  . ....     .||.|||||.   .  |.   . .||...||||||. ... ..
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA----CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KSDVWSFGVVLWEILTGEKPYSGL------DMFVVAYGVGHGTLTLPIPEHCP-------------------LSLRDLMSCCWKREHSKRPSFTQVKEK-
|.|.||.|..|.| |.|. |..|       |. .. . .... |  ..|. |.                    ...|....|...  .|||...|...  
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

-L
 .
WF
Kinase AqueK659.AA TK 187-446 20 1.3e-73 245.93 In-house 1-486 (486) Show / Hide 
Range on Protein: 187-446
Range on HMM: 1-486/486
Sequence Identity: 20% (102 aa)

IKLGDVIGLGGFG---KVYRAQYKG---------------------------EDVAVKVARHTTYDTMKAVSD--------------VLSEAEKFAH--L
|.||...| | ||   .||.....|                           ..||||. . .. .....  |               ..|.... |  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

AHENVCALIGVCLVKD-------------VCLVMEYAKGGP----LSKILHERNIT--------------------------------------------
 |.|.  |.|||. ..             ...||||...|     | . |...  .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTVDIILDWSRQITEGMEYLHHE----ITPSLIHRDLKSSNILLQYEV-----NPADLKGNLIKITDFG
                               ||.   | ...|| .||||||      | . ..||||   |.|.  .      .  |  |  .||.|||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHF--DGCGPVCKIADFG

--------LAREI---ENTTHLSGAGT-------------------------YPWMAPEVIKSSE---------FSKKSDVWSFGVVLWEILT-GEKPYS
        |||.|   .. .  |. ||                           |||||.... .         |. |||||||||..|||.| |..|| 
LSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYY

G------------LDMFVVAYGVG-----------HGTLTLPIPEHCP--------------LSLRDLMSCCWKREHSKRPSFTQVKEKL
|            .. ..     |            . . .| |.|||                . ||| .||... ..||.|.|..|.|
GGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK659.AA TKL-Unique 189-446 34 3.9e-73 249.28 In-house 1-290 (290) Show / Hide 
Range on Protein: 189-446
Range on HMM: 1-290/290
Sequence Identity: 34% (101 aa)

LGDVIGLGGFGKVYRAQYKGEDVAVKVARHTTYDTMKAVSD-VLSEAEKFAHLA-HENVCALIGVCL-----VKDVCLVMEYAKGGPLSKILH-------
 . .|| ||.|.||.. ..|..||.|.      |  . ...   .|      |  |.|.  ..|.|       .. |.||||  || | . ||       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--ERNITLTVDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITDFGLAREIE--NTTHLSGA---------GTYPWMAP
  ..|..|.   ...  ..|  ||.||||...|  |||||||||.|.  . | | ..   ||| ||||..     |.. ...          |.. ||||
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWN---IKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAP

EVIKS--SEFSKKSDVWSFGVVLWEILTGEK------PYSGLDMFVVAYGVGH--GTLTLPIPEHCPLSLRDLMSCCWKREHSKRPSFTQVKEKL
||...  . .|.||||.|||.|||||.|..       ||.|.|   ..  |      . .|||.||| ..|||.  ||....|.||||... ..|
EVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK659.AA LZK 239-446 42 3.7e-67 225.47 In-house 43-241 (241) Show / Hide 
Range on Protein: 239-446
Range on HMM: 43-241/241
Sequence Identity: 42% (89 aa)

HLAHENVCALIGVCLVKDV-CLVMEYAKGGPLSKILHERNITLTVDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITD
.| |.|. .. |||    . | .|||   |.| ..| ||. |.|   . |||.|| .||.|||       ||||||| |||  ..        . .|| |
KLKHPNIIEFKGVCTQSPCYCIIMEYCPHGQLYEVLRERR-TITPQLMVDWSKQIAQGMHYLHQHK---IIHRDLKSPNILISHN--------DVVKICD

FGLAREIENT--THLSGAGTYPWMAPEVIKSSEFSKKSDVWSFGVVLWEILTGEKPYSGLDMFVVAYGVGHGTLTLPIPEHCPLSLRDLMSCCWKREHSK
||  .. ..   | .| .||  |||||||.    | | |.|||||||||.||.| ||   |   . .|||   | ||.|. ||  .. ||  ||.     
FGTSHMWNEMDSTKMSFCGTVAWMAPEVIRNEPCSEKVDIWSFGVVLWEMLTCEIPYKDVDSMAIIWGVGSNSLHLPMPSTCPEGFKLLMKQCWSQKPRN

RPSFTQVKEKL
|||| |.   .
RPSFRQILMHW
Kinase AqueK659.AA S_TKc 187-455 26 1.3e-62 215.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 187-455
Range on HMM: 1-231/231
Sequence Identity: 26% (75 aa)

IKLGDVIGLGGFGKVYRAQYKG--EDVAVKVARHTTYDTMKAVSDVLSEAEKFAHLAHENVCALIGVCLVKDVCLVMEYAKG--GPLSKILHERNI----
 .....|| |.|||||... |.  . ||.|. .           ....| .   .  |.|.. |..|.  .....||||. |  | | .....|.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

-TLTVDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITDFGLAREIENTTHLSGAGTYPWMAPEVIKSSEFSK-KSDVW
  ..   .  . .|| ...||.|       |||||| .||||             |||.||||||..      .  ||  .|||||.    ..| |.|.|
FPFPE-HARFYMYQICCALEYCHSH---GIIHRDLKPENILLDE----------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWW

SFGVVLWEILTGEKPYSGLDMFVVAYGVGHGTLTLPIPEHCPLSLRDLMSCCWKREHSKRPSFTQVKEKLVEIQKTEFL
|.|..|.| |.|. |..  .|...   .|            . ...|... |.... .|||.  .. .  ..| . ...
SCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK659.AA Dicty4 187-448 31 5e-62 205.71 In-house 1-277 (277) Show / Hide 
Range on Protein: 187-448
Range on HMM: 1-277/277
Sequence Identity: 31% (89 aa)

IKLGDVIGLGGFGKVYRAQYKGEDVAVKVA-RHTTYDTMKAVSDVLSEAEKFAHLAHENVCALIGVCL----VK-DVCLVMEYAKGGPLSKILHE-----
|. .. || |.||.||..  .| .||||..  | . .  .  .. . |..  . . | |.| . | |.     . ..| |.||   | | ..||      
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-RNITLTVDIILD---WSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITDFGLAR----EIENTT-HLSGAGTYPWMAPEVIKS
  .|.|    |.      . .  || .| |. .|  |||||||.|.|     .        .|..||||..    ......   . .||  ||||||  .
QQSIKLDWPLIKRAMRMAFDAARGMNWL-HCCNPVIIHRDLKSHNLLVDKNWR--------VKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMH

SEFSKKSDVWSFGVVLWEILTGEKPYS--GLDMFVVAYGVGHGTLTLPIPEHCPLSLRDLMSCCWKREHSKRPSFTQVKEK--LVE
 ..  |.|| ||| |||||||.. ||.  . . . .. .|.   | .|||  || |...|.  ||  . ..|||| .. ..  | .
QPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK659.AA ZAK 187-445 34 4.7e-59 202.51 In-house 1-257 (257) Show / Hide 
Range on Protein: 187-445
Range on HMM: 1-257/257
Sequence Identity: 34% (95 aa)

IKLGDVIGLGGFGKVYRAQYKGED-VAVKVARHTTYDTMKAVSDVLSEAEKFAHLAHENVCALIGVCLVKDV--CLVMEYAKGGPLSKILH-ERNITLT-
| ..| .| | || ||||.    |     .|       .| |  .  |||    . | |.    |.|.        | |||  | |    | .|   .  
IQFFDHCGVGTFGSVYRANWISQDGSQREIA-------VKKVFKIEKEAEILSKIRHRNIIQFYGICKEPPNDYFIVTEYAEKGSLYDYIHSNRSQEMDS

------VDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITDFGLAREIEN-TTHLSGAGTYPWMAPEVI-KSSEFSKKS
       | |. |  ||  || ||| .     ||||||| |. .      ...    .|| |||  |.. . .|| |  || ||||||.|  |   .   
SSGGNSMDHIMKWATQIAKGMHYLHMDAPDKIIHRDLKSRNVVID-----KNG---VCKICDFGTSRDFHHHCTHMSWVGTFPWMAPEMILQSEPVTETC

DVWSFGVVLWEILTGEKPYSGLDMFVVAYGVGHGTLTLPIPEHCPLSLRDLMSCCWKREHSKRPSFTQVKEK
||||.||||||.|| | || ... | ..  .     .| ||  || ....||. ||| .  .||.. |.   
DVWSYGVVLWEMLTREVPYKDYEEFQIFWMIVQKNIRLTIPPSCPRPFKQLMHQCWKMDPKDRPNMRQIQSI
Kinase AqueK659.AA Fer 187-447 30 1.5e-54 184.16 In-house 1-283 (283) Show / Hide 
Range on Protein: 187-447
Range on HMM: 1-283/283
Sequence Identity: 30% (88 aa)

IKLGDVIGLGGFGKVYRAQ-----YKG-----EDVAVKVARH-TTYDTMKAVSDVLSEAEKFAH-LAHENVCALIGVCLVKD-VCLVMEYAKGGPLSKIL
..||...| | ||.||...     .||     ..|||||... .. .|..   ... ||      . | || ...|||  .  . .|||...|| | . |
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

HERNI-TLTVDIILDWSRQITEGMEYLHHEITPSLIHRDLKSSNILLQY-EVNPADLKGNLIKITDFGLARE--IENTTHLSG--AGTYP--WMAPEVIK
 .    |.... ... . |.  ||||||       ||||. . |.|.   .|.         ||.|||..|.   . .. . .  |   |  |.|||...
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKN---CIHRDIAARNCLYHKDKVKKK------CKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQ

SSEFSKKSDVWSFGVVLWEILT-GEKPYSG----LDMFVVA----YGVGHGTLTLPIPEHCPLSLRDLMS-CCWKREHSKRPSFTQVKEKLV
. ..|.|.|||||||..||| | |..|| |    . | .|.      . ..   .|.|.|.|  .. .|  .||... ..||.......|| 
TGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK659.AA TK-Unique 187-446 29 8e-54 183.96 In-house 1-294 (294) Show / Hide 
Range on Protein: 187-446
Range on HMM: 1-294/294
Sequence Identity: 29% (91 aa)

IKLGDVIGLGGFGKVYRAQYK------GEDVAVKVARHTTYDTMKAVSDVLSEAEKFAHLA-HENVCALIGVCL-VK-DVCLVMEYAKGGPLSKILHERN
...||||| | || |.|....      .... | |  .  . |   ..| |.|.. . .|  |.|.  ..|.|     .....|||. .| | . |... 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

IT-------------------------LTVDIILDWSRQITEGMEYLHH---EITPSLIHRDLKSSNILLQYEVNPADLKGNLIKITDFGLAREIEN---
 .                         ..    . .  ||  |||||.    .|    .|||| ..|.||.         .. .||.|||.||....   
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI----VHRDLCARNVLLTE--------DKVCKICDFGMARDVYTNGV

--TTHLSGAGTYPWMAPEVIK--SSEF-SKKSDVWSFGVVLWEILT-GEKPYSGLDMFVVAYGVGHGTLTLPIPEHC-PLSLRDLMSCCWKREHSKRPSF
  ..  .|   . |||||..|     . . |||||||||..|||.| |. ||.|..   .   .  |  ..| |||| .  .. ||..||..| ..||||
YSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDG-YRMPQPEHCCSHEMYNLMKSCWQWEPEERPSF

TQVKEKL
.|.| .|
RQIKHRL
Kinase AqueK659.AA LZK 187-214 39 0.024777 3.58 In-house 1-28 (241) Show / Hide 
Range on Protein: 187-214
Range on HMM: 1-28/241
Sequence Identity: 39% (11 aa)

IKLGDVIGLGGFGKVYRAQYKGEDVAVK
|.  . .| |  | |.| ....| ||||
ISELQWLGSGAQGAVFRGWFRNETVAVK