Gene RSK-p2_b-2 (S.moellendorffii)

RSK-p2_b-2

Species: S.moellendorffii
Alias: RSK-p2_b-2
External Links:
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSK-p2

Sequence

Name Sequence Type Origin Length Description Download
RSK-p2_b-2.AA Protein None 525 None Fasta, JSON
RSK-p2_b-2.NA RNA None 1578 None Fasta, JSON
RSK-p2_b-2.kin_dom Protein Kinase Domain None 337 None Fasta, JSON

Protein domain

Protein domains of RSK-p2_b-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RSK-p2_b-2.AA AGC 119-455 25 2.3e-141 368.07 In-house 1-395 (395) Show / Hide 
Range on Protein: 119-455
Range on HMM: 1-395/395
Sequence Identity: 25% (116 aa)

FRLLKRLGCGDIGSVYLAELR------STSCYFAMKVMDKGS---LASRKKVLRAQTE------------KEILSLLD----------HPFLPT-LYTHF
|..|| .| |  | |||.. .      .|  |.||||..|     .  ...| ...||            ..||....          |||.   |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETDKF--SCLVMEFCT---------GG-DLHTLRQRQ-PNKHFTEQAARFYASE-------VLLALEYLHM-LGIVYRD-LKPENVLVREDGHIMLSDFD
....    ..|||..          || .|..  | .  ...|.|..|||||.|       ..|||||||  .||..|| |||||.|  |||||.|.|| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSLRCVVSP--------------------------TLVKSAALDGDPLRRLPLYCVQPSCVQPACIQPVCAQPSCFLPRLLPQISKKGRKSKNDVGNQVS
|. . . ..                          .                                                              . 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTN--------------------------------------------------------------K-

PLPELVAEPT-----------GARSMSFVG--THEYLAPEIIKGEGHGSAVDWWT--FGIFLYELLHGKTPFKGTG---------NRATLFNVVG-----
  |.   .             ..|  .|.|  |.||.||||.    .| |.|||.  .|...||.| |..|| |           |.. .|. .      
CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYF

--QPLKFPEA--------SEVGFPARDLIRGLLVKDPQHRLGSKR------GATEIKQHPFF
  ...|||          ...   |.|||..||.||| .|||...      || |||.||.|
INWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase RSK-p2_b-2.AA S_TKc 119-455 25 1.4e-88 301.51 SMART 1-231 (231) Show / Hide 
Range on Protein: 119-455
Range on HMM: 1-231/231
Sequence Identity: 25% (88 aa)

FRLLKRLGCGDIGSVYLAELRSTSCYFAMKVMDKGSLASRKKVLRAQTEKEILSLLDHPFLPTLYTHFETDKFSCLVMEFCTG--GDLHTLRQRQPNKH-
...|. .| |  |.||..  ..|  ..|.|...           ... | .||.  .||.. .|| .|.. .. ..|||.| |  |||... .... .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEQAARFYASEVLLALEYLHMLGIVYRDLKPENVLVREDGHIMLSDFDLSLRCVVSPTLVKSAALDGDPLRRLPLYCVQPSCVQPACIQPVCAQPS
   |.|  ||||. ....||||.| .||..|||||||.|. |  ||...|| |. .                                            
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

CFLPRLLPQISKKGRKSKNDVGNQVSPLPELVAEPTGARSMSFVGTHEYLAPEIIKGEGHGS-AVDWWTFGIFLYELLHGKTPFKGTGNRATLFNVVGQP
                                        ..|.|| .|.|||..   |.|  ..||| .|. |||.| |..||    . ...|...|  
----------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--

LKFPEASEVGFPARDLIRGLLVKDPQHRLGSKRGAT---EIKQHPFF
           .|.|.||..|.|||..|..     .   .||.||.|
---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RSK-p2_b-2.AA RSK 122-455 30 2.4e-88 299.83 In-house 1-278 (278) Show / Hide 
Range on Protein: 122-455
Range on HMM: 1-278/278
Sequence Identity: 30% (109 aa)

LKRLGCGDIGSVYLAELR---STSCYFAMKVMDKGSLASRKK-VLRAQTEKEILSLLD-HPFLPTLYTHFETDKFSCLVMEFCTGGDLHTLRQRQPNKH-
|| || |. |.|.|        |  ..|||| .|  .. |.| . .. || .||..   |||. ||.  |.|..   |.||.| ||.| |  |..  || 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKE--KHF

--FTEQAARFYASEVLLALEYLHMLGIVYRDLKPENVLVRE---DGHIMLSDFDLSLRCVVSPTLVKSAALDGDPLRRLPLYCVQPSCVQPACIQPVCAQ
  |.|  |.||..|. ||.|.|| .||..|||||||.|  .   .|||.|.||...                                            
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----------------------------------------

PSCFLPRLLPQISKKGRKSKNDVGNQVSPLPELVAEPT-GARSMSFVGTHEYLAPEIIK----GEGHGSAVDWWTFGIFLYELLHGKTPFKG---TGNRA
                                    .  . . |.|..|.||.|||..|    ..||. |.|||..|. .||.| |..||.|        
-----------------------------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKE

TLFNVVGQP--LKFPEASEVGFPARDLIRGLLVKDPQHRLGS-KRGATEIKQHPFF
.. ..      |..|. ...  .|.||||..| .||. |||. ...| ||||||.|
IMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RSK-p2_b-2.AA RSK-Unclassified 119-266 44 2.4e-63 197.64 In-house 1-148 (283) Show / Hide 
Range on Protein: 119-266
Range on HMM: 1-148/283
Sequence Identity: 44% (66 aa)

FRLLKRLGCGDIGSVYLAELRSTSCYFAMKVMDKGSLASRKKVLRAQTEKEILSLLDHPFLPTLYTHFETDKFSCLVMEFCTGGDLHTLRQRQPNKHFTE
|   . .| ||.| ||| . . |   .||||. |  .  ..|. .. ||..|... .|||  |||  | |     |.||.| |||.    |    | |.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

QAARFYASEVLLALEYLHMLGIVYRDLKPENVLVREDGHIMLSDFDLS
  .||||||| .|||||| ....||||||.|..   .||.||.|||||
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLS
Kinase RSK-p2_b-2.AA RSK-Unclassified 349-455 50 8.4e-53 163.92 In-house 176-283 (283) Show / Hide 
Range on Protein: 349-455
Range on HMM: 176-283/283
Sequence Identity: 50% (54 aa)

GARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGTGNRATLFNVVGQPLKFPEASEVGFPARDLIRGLLVKDPQHRLGSKRG-AT
| |  ||.|| ||||||.|.. ||. |||||| || .||.| | .|..|     |  |.  ...|||. |..   .||||. || . |  |||.|.| | 
GFRTNSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDAD

EIKQHPFF
.||.||||
DIKRHPFF
Kinase RSK-p2_b-2.AA AktR 119-266 41 5.3e-49 169.12 In-house 1-149 (268) Show / Hide 
Range on Protein: 119-266
Range on HMM: 1-149/268
Sequence Identity: 41% (62 aa)

FRLLKRLGCGDIGSVYLAELR-STSCYFAMKVMDKGSLASRKKVLRAQTEKEILS-LLDHPFLPTLYTHFETDKFSCLVMEFCTGGDLHTLRQRQPNKHF
|...| || |  | |||.. .  .  ..|||. .|  .  |..  ...||. |.  . .|||.  |.  |.|.. . ..||.| ||.| .  ..  .|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKK--KKKF

TEQAARFYASEVLLALEYLHML-GIVYRDLKPENVLVREDGHIMLSDFDLS
.|. ||||....||||||||    |.|||||||| |  ||||. ..|| ||
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLS
Kinase RSK-p2_b-2.AA PKA 119-263 38 2.3e-46 160.37 In-house 1-145 (263) Show / Hide 
Range on Protein: 119-263
Range on HMM: 1-145/263
Sequence Identity: 38% (56 aa)

FRLLKRLGCGDIGSVYLAELRSTSCYFAMKVMDKGSLASRKKVLRAQTEKEILSLLDHPFLPT-LYTHFETDKFSCLVMEFCTGGDLHTLRQRQPNKHFT
| ... || |  | |.|.  ... .|.|||...|     .| | .  .|| ||....|||. . .| .| .|..  .|||.. ||.. .  ..  ...|.
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRK--SGRFS

EQAARFYAS-EVLLALEYLHMLGIVYRDLKPENVLVREDGHIMLSDF
.. |.|||  .. ||||||| . |.|||||||| |  ..||| . ||
NPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDF
Kinase RSK-p2_b-2.AA SGK 354-455 47 1.2e-45 138.6 In-house 184-283 (283) Show / Hide 
Range on Protein: 354-455
Range on HMM: 184-283/283
Sequence Identity: 47% (49 aa)

SFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGTGNRATLF-NVVGQPLKFPEASEVGFPARDLIRGLLVKDPQHRLGSKRGATEIKQH
.| || ||||||......|. .||||  |..|||...|. ||    |..... |   |||..|    .  .|.||| ||| |||. |||.||.. |||.|
TFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSR-NKQQMYDNIINQPLQIPP--QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNH

PFF
|||
PFF
Kinase RSK-p2_b-2.AA SGK 119-266 35 4.6e-45 136.81 In-house 1-172 (283) Show / Hide 
Range on Protein: 119-266
Range on HMM: 1-172/283
Sequence Identity: 35% (61 aa)

FRLLKRLGCGDIGSVYLAELRST------------------SCYFAMKVMDKGSLA-------SRKKVLRAQTEK-EILSLLDHPFLPTLYTHFETDKFS
|..|| .| |  | ||...  ..                     .||||  | .          .|..   ..|.  ||... |||.  |   | |..  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CLVMEFCTGGDLHTLRQRQPNKHFTEQAARFYASEVLLALEYLHMLGIVYRDLKPENVLVREDGHIMLSDFDLS
 .||..  ||..    ||   ||| |  |||||.|. .|||||| . |.||||||||.|   .||. | || |.
YFVMDYVNGGEMFYHLQRE--KHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC
Kinase RSK-p2_b-2.AA Akt 353-455 46 1.5e-43 137.03 In-house 160-264 (264) Show / Hide 
Range on Protein: 353-455
Range on HMM: 160-264/264
Sequence Identity: 46% (49 aa)

MSFVGTHEYLAPEIIKGEGHGSAVDWWT-FGIFLYELLHGKTPFKGTGNRATLF-NVVGQPLKFPEASEVGFPARDLIRGLLVKDPQHRLG-SKRGATEI
..| || |||||||..| ||. |||||. .|...||...|  ||    .. ..| .   ||.|||. . .   ..|||.||| ||| .|||  . .| ||
KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYN-QDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEI

KQHPFF
|.||.|
KRHPWF
Kinase RSK-p2_b-2.AA AktR 354-455 43 1.5e-43 151.04 In-house 163-268 (268) Show / Hide 
Range on Protein: 354-455
Range on HMM: 163-268/268
Sequence Identity: 43% (46 aa)

SFVGTHEYLAPEIIKG-EGHGSAVDWWTFGIFLYELLHGKTPFKGTGNRATLFNVVGQP-LKFPEASEVGFPARDLIR-GLLVKDPQHRLG-SKRGATEI
||.||.||.|||.|.  .||. .||||.||||.||.. | .||    ..  ...   .. .|||. |.. . ..|||  .|| |.|..||| .. |..||
SFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEI

KQHPFF
| ||.|
KSHPWF
Kinase RSK-p2_b-2.AA Akt 119-263 42 4.3e-43 135.56 In-house 1-145 (264) Show / Hide 
Range on Protein: 119-263
Range on HMM: 1-145/264
Sequence Identity: 42% (63 aa)

FRLLKRLGCGDIGSVYLAELRSTSCYF-AMKVMDKGSLASRKKVLRAQTEKEILSLLDHPFLPTLYTHFETDKFSCLVMEFCTGGDLHTLRQRQPNKHFT
|..|| || |  | |.|..  .|  .. ||||  |  .  ...|  ..||. ||   .|||.  |.  | | .  ..||..| ||.| .. ||.  . |.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRK--RRFS

EQAARFYASEVLLALEYLHMLGIVYRD-LKPENVLVREDGHIMLSDF
|. ||||..|. ||.|.||  .|.||| |||||.|. .|||| | ||
EDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDF
Kinase RSK-p2_b-2.AA RSK 119-266 34 5.2e-42 145.88 In-house 1-152 (271) Show / Hide 
Range on Protein: 119-266
Range on HMM: 1-152/271
Sequence Identity: 34% (53 aa)

FRLLKRLGCGDIGSVYLAELR---STSCYFAMKVMDKGSLASRKKVLRAQTEKEILSLLDHPFLPTLYTHFETDKFSCLVMEFCTGGDLHTLRQRQPNKH
. |.. .| |  . ||.        |  ..|||. .| ... . .  .. .|  ||.  .|||  .|.  |.. .   ..|.|. |||| .  ..|  | 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQ--KM

FTEQAARFYASEVLLALEYLHMLGIVYRDLKPENVLVRED----GHIMLSDFDLS
|.|. ..||..|..||.|||| .|||.|||||||.|. ..    ||| . || ..
FSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA
Kinase RSK-p2_b-2.AA Pkinase 119-266 33 7.8e-41 145.47 Pfam 1-159 (293) Show / Hide 
Range on Protein: 119-266
Range on HMM: 1-159/293
Sequence Identity: 33% (54 aa)

FRLLKRLGCGDIGSVYLAELRSTSCYFAMKVMDKGSLASRKKVLRAQ-TEKEILSLLDHPFLPTLYTHFETDKFSCLVMEFCTGG----DLH----TLRQ
.......| |  |.||..  ..|.. .|.|...| .  | |.. ..  .| .|.  |.||.  .||  ||...  ..|||.| ||    ||.    |   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

RQPNKHF--TEQAARFYASEVLLALEYLHMLGIVYRDLKPENVLVREDGHI----MLSDFDLS
 . .. |  .|. ..||. ..| .|||.|  ||..|||||||.|. ..|||     ..|| |.
-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase RSK-p2_b-2.AA Ciliate-E2 119-266 26 3e-40 135.85 In-house 1-203 (365) Show / Hide 
Range on Protein: 119-266
Range on HMM: 1-203/365
Sequence Identity: 26% (56 aa)

FRLLKRLGCGDIGSVYLAELRSTSC-----------------------YFAMKVMDKGSLASRKKVLRAQ----------TEKEILSLLDHPFLPTLYTH
. ..| .| |  ||||... ... .                       ..|||.| |  . . |....             ||.||..|.||..  .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--TDKFSCLVMEFCTGGDLHT-LRQR----------------QPNKHFTEQAAR-------FYASEVLLALEYLHMLG-IVYRDLKPENVLVREDGHI
|.  .|.   ||||.| ||||   ....                .  |....| ..       ||. ...|||||||  . |..||.||||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

MLSDFDLS
 ..|| ||
KIIDFGLS
Kinase RSK-p2_b-2.AA MAST 119-266 40 3.3e-38 120.53 In-house 1-146 (334) Show / Hide 
Range on Protein: 119-266
Range on HMM: 1-146/334
Sequence Identity: 40% (60 aa)

FRLLKRLGCGDIGSVYLAELRSTSCYFAMKVMDKGSLASRKKVLRAQTEKEILSLLDHPFLPTLYTHFETDKFSCLVMEFCTGGDLHTLRQRQPNKHFTE
|   | .. |  | |||.. ..|   |||||..|  .. .. |   |.|. ||.... ||   ..  |.|..  |.|||.  |||. .|  .  .  | |
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASL-LHMYG-YFDE

QAARFYASEVLLALEYLHMLGIVYRDLKPENVLVREDGHIMLSDFDLS
  |..| .|. |.|||||  ||| |||||.|.|   .||| | || ||
WMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase RSK-p2_b-2.AA MAST 356-455 41 4.2e-37 116.92 In-house 225-334 (334) Show / Hide 
Range on Protein: 356-455
Range on HMM: 225-334/334
Sequence Identity: 41% (46 aa)

VGTHEYLAPEIIKGEG-HGSAVDWWTFGIFLYELLHGKTPFKGTGNRATLFNVVGQP---LKFPEA------SEVGFPARDLIRGLLVKDPQHRLGSKRG
.|| .|.|||.|.|.| || .||||  || .||.| | .|| .     .  |..       ..||       ..   .|.|||. ||  ||  |||.. |
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

ATEIKQHPFF
|.|.||||||
ADEVKQHPFF
Kinase RSK-p2_b-2.AA PKA 357-455 39 1.1e-30 108.29 In-house 160-263 (263) Show / Hide 
Range on Protein: 357-455
Range on HMM: 160-263/263
Sequence Identity: 39% (42 aa)

GTHEYLAPEIIKGE-GHGSAVDWWTFGIFLYELLHGKTPFKGT--GNRATLFNVVGQPLKFPEASEVGFPA---RDLIRGLLVKDPQHRLGSKR-GATEI
|| ||||||||... ||| .||||..||  ||.| |..||  .     ..    .   .|||  ...   |   .|||. ||..|.  |.|... |.  |
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFP--RHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDI

KQHPFF
| |..|
KNHKWF
Kinase RSK-p2_b-2.AA Ciliate-E2 354-455 26 3.9e-30 100.62 In-house 246-365 (365) Show / Hide 
Range on Protein: 354-455
Range on HMM: 246-365/365
Sequence Identity: 26% (35 aa)

SFVGTHEYLAPEIIKGEG---------HGSAVDWWTFGIFLYELLHGKTPFKGTGNRATLFNVVGQPLKFPEA--------------SEVGFPAR--DLI
...|| .|.||||..|..         .. ..|.| .|. |||.| ||.||        . .   ....||..              |    .    |||
TICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLI

RG----LLVKDPQHRLGSKRGATEIKQHPFF
.     .|.|||. |..   |. .|..||.|
KKFGKRMLQKDPEKRIT---GWEQILNHPWF
Kinase RSK-p2_b-2.AA Pkinase 346-455 28 8.1e-30 106.51 Pfam 164-293 (293) Show / Hide 
Range on Protein: 346-455
Range on HMM: 164-293/293
Sequence Identity: 28% (39 aa)

EPTGARSMSFVGTHEYLAPEIIK-GEGHGSAVDWWTFGIFLYELLHGKTPFKGT------GNRATLFNVVGQPLKFPEASEVG-----------------
.  .   ..|.|| .|.|||.|. |...|..||.| .|. |||.| |..||.|         .. .... | ||.|..  .                   
Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHN

--FPARDLIRGLLVKDPQHRLGSKRGATEIKQHPFF
   ...|.|...| |||. |..    |..|.|||.|
WSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase RSK-p2_b-2.AA RSK 353-455 37 1.6e-28 99.01 In-house 163-271 (271) Show / Hide 
Range on Protein: 353-455
Range on HMM: 163-271/271
Sequence Identity: 37% (41 aa)

MSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLHGKTPFKGTGNRATLFNVVGQPLKF-----PEASEVGFPARDLIRGLLVKDPQHRLGS-KRGA
|.| .| .|.|||..|  ||. |.||| ||. .|| |.| ||| .. .  .  . . ..|       .  . .  .| ||.|..|  ||. |||.   |.
MTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGV

TEIKQHPFF
 .|||||.|
EQIKQHPWF
Kinase RSK-p2_b-2.AA TyrKc 119-449 15 9.2e-09 -80.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 119-449
Range on HMM: 1-280/280
Sequence Identity: 15% (60 aa)

FRLLKRLGCGDIGSVYLAELRSTSCYFAMKVMDKGSLASRKKVLRAQTEKEILSLL--DHPFLPTLYTHFETD-------KFSCLVMEFCTGGDLHTLRQ
 .|.| ||.|  | ||.....      | |.. ...   |.  .|   | .|.. |  .|| .  ||    ..       .  ..|||.. .|||.   .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMR---EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RQPNKHFTEQAARFYASEVLLALEYLHMLGIVYRDLKPENVLVREDGHIMLSDFDLSLRCVVSPTLVKSAALDGDPLRRLPLYCVQPSCVQPACIQPVCA
.  .| .. .    ..  .    ||||  ... |||   |.|| |..                                                     
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------------------------------------------------

QPSCFLPRLLPQISKKGRKSKNDVGNQVSPLPELV-------AEPTGAR-------SMSFV----GTHE-----YLAPEIIKGEGHGSAVDWWTFGIFLY
                                  |       .   .         ..  .    |..       .||| |.     .. | | ||. ..
---------------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMW

ELL-HGKTPFKG-----TGNRATLFNVV-GQPLKFPEA-----SEVGFPAR--DLIRGLLVKDPQHRLGSKRGATEI
|..  |..|  |       |.  . .|  |  .. |.      . |. |.   ....     ||  |   .    ..
EIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RSK-p2_b-2.AA Pkinase_Tyr 119-206 26 0.001003 13.24 Pfam 1-96 (270) Show / Hide 
Range on Protein: 119-206
Range on HMM: 1-96/270
Sequence Identity: 26% (26 aa)

FRLLKRLGCGDIGSVYLAELR----STSCYFAMKVMDKGSLAS---RKKVLRAQTEKEILSLL-DHPFLPTLYTHFE-TDKF--SCLVMEFCTGGDLHT
 ...| || |  |.||.....    .| .  | |..  |.  .   |.. .|   | .|.. | .|| .  ||      ..    ..|||.. .|||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR---EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase RSK-p2_b-2.AA Pkinase_Tyr 379-397 33 1.095207 2.95 Pfam 198-218 (270) Show / Hide 
Range on Protein: 379-397
Range on HMM: 198-218/270
Sequence Identity: 33% (7 aa)

WTFGIFLYELLH-GKTP-FKG
| ||. ..|..  |..| ..|
WSFGVLMWEIFTYGEQPTYPG