Gene RSK-p3_d-1 (S.moellendorffii)

RSK-p3_d-1

Species: S.moellendorffii
Alias: RSK-p3_d-1
External Links:
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSK-p3

Sequence

Name Sequence Type Origin Length Description Download
RSK-p3_d-1.AA Protein None 455 None Fasta, JSON
RSK-p3_d-1.NA RNA None 1368 None Fasta, JSON
RSK-p3_d-1.kin_dom Protein Kinase Domain None 335 None Fasta, JSON

Protein domain

Protein domains of RSK-p3_d-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RSK-p3_d-1.AA AGC 21-355 27 6.5e-139 361.56 In-house 1-395 (395) Show / Hide 
Range on Protein: 21-355
Range on HMM: 1-395/395
Sequence Identity: 27% (126 aa)

FNALKRLGYGDMGTVFLATLR------NTGQPLAMKVMNKEV-VKARH--NQYRVERE------------LEILSMLS----------HSFTPK-LFSHF
|. || .| |  |.|.|.  .       ||.  ||||..|.. .. .    . .. .|             .||....          | |  | |.. |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ESKKN--IYFVMDYCP--------GGDMNRLRQRQ---PEKRFSENAARFYAAE-------VCLAIEYLHK-SGIIYRD-LKPENVLIQEDGHIMLTDFD
..|..  .||||.|.|        ||..  . . |    |.||.|..|||||||       ..||.||||.  |||.|| |||||.|. |||||.|||| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSVRIEQD--------------------RDHHHHPGAPAPAPAPQPKQNKMKKLPFMCSTPLSVDVGCAARKAVDVKPSHRPTKKIFPSEMRGRKGAAAA
|. .. .|                    . .                  .|.  . .                                           
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQ-KS-----------------NMD--T-N---------------------------------------K-CN

AAAAKEIK--------------SQSFVG--TEEYVAPEMILGSGHGKPLDWWT--LGVFLYEMIYGVTPFKGRN----------RRETFLNIL------S
.. ... .               ..|.|  | ||.|||..    .||. |||.  ||...|||..| .|| | |          . |.| .|.      .
PNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFIN

SQPAFP----------GDW-TEASDLISKLLAKDPTKRLGCQG------GAEEIKSHAFF
 .. ||            .  || |||.||| |||.|||||.|      ||||||.| .|
WKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase RSK-p3_d-1.AA AktR 21-355 33 2e-93 316.72 In-house 1-268 (268) Show / Hide 
Range on Protein: 21-355
Range on HMM: 1-268/268
Sequence Identity: 33% (114 aa)

FNALKRLGYGDMGTVFLATLR-NTGQPLAMKVMNKEVVKARHNQYRVERELEILS-MLSHSFTPKLFSHFESKKNIYFVMDYCPGGDMNRLRQRQPEKRF
|  .| || |  |.|.|.. . ....  |||.  |.  . |  . .. .|  |.  . .|.|  ||.  |..|....|.|.|||||.. .  ..  .|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKK--KKKF

SENAARFYAAEVCLAIEYLHKS-GIIYRDLKPENVLIQEDGHIMLTDFDLSVRIEQDRDHHHHPGAPAPAPAPQPKQNKMKKLPFMCSTPLSVDVGCAAR
||. ||||.|...||.||||.   |||||||||| |. ||||. .||| ||                                                 
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK------------------------------------------------

KAVDVKPSHRPTKKIFPSEMRGRKGAAAAAAAAKEIKSQSFVGTEEYVAPEMILG-SGHGKPLDWWTLGVFLYEMIYGVTPFKGRNRRETFLNILSSQ--
                                ... | .||.|| ||.|||||.   ||.|. |||..|.|.|||..| .||   |... |..|...|  
---------------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQN

-PAFPGDW-TEASDLIS-KLLAKDPTKRLG-CQGGAEEIKSHAFF
 . .| .   .. |||  ||| |.|.||||    |.|||||| .|
KFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase RSK-p3_d-1.AA S_TKc 21-355 26 7.4e-88 299.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-355
Range on HMM: 1-231/231
Sequence Identity: 26% (91 aa)

FNALKRLGYGDMGTVFLATLRNTGQPLAMKVMNKEVVKARHNQYRVERELEILSMLSHSFTPKLFSHFESKKNIYFVMDYCPG--GDMNRLRQRQPEKR-
.  |. .| | .|.|.... ..||.  |.|...           ...||..||..  | .  ||. .|.. ...|.||.||.|  ||. .. .... .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSENAARFYAAEVCLAIEYLHKSGIIYRDLKPENVLIQEDGHIMLTDFDLSVRIEQDRDHHHHPGAPAPAPAPQPKQNKMKKLPFMCSTPLSVDVGC
   |.|  ||||....|.|.||.|. |||.|||||||.|. |  ||...|| |. ..                                           
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

AARKAVDVKPSHRPTKKIFPSEMRGRKGAAAAAAAAKEIKSQSFVGTEEYVAPEMILGSGHGK-PLDWWTLGVFLYEMIYGVTPFKGRNRRETFLNILSS
                                          .|.|| .|.|||..   |.|| . ||| .|. ||||..| .||   .  ..| .|.  
-----------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--

QPAFPGDWTEASDLISKLLAKDPTKRLGCQGGAE---EIKSHAFF
         || |.|.|.| |||.||...    .   .||.| .|
-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RSK-p3_d-1.AA RSK 24-355 32 4.4e-86 292.3 In-house 1-278 (278) Show / Hide 
Range on Protein: 24-355
Range on HMM: 1-278/278
Sequence Identity: 32% (114 aa)

LKRLGYGDMGTVFLATLR---NTGQPLAMKVMNKEVVKARHN-QYRVERELEILSMLS-HSFTPKLFSHFESKKNIYFVMDYCPGGDMNRLRQRQPEKR-
|| || |. | |||       .|||  |||| .| ....|   . .. .| .||..   | |  .|.  |. .. .| .|.||.||..  ..  | ||. 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGEL--FTHLQKEKHF

--FSENAARFYAAEVCLAIEYLHKSGIIYRDLKPENVLIQE---DGHIMLTDFDLSVRIEQDRDHHHHPGAPAPAPAPQPKQNKMKKLPFMCSTPLSVDV
  |||. |.||.||. ||.|.||. |||.|||||||.|  .   .|||.||||...                                            
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----------------------------------------

GCAARKAVDVKPSHRPTKKIFPSEMRGRKGAAAAAAAAKEIKSQSFVGTEEYVAPEMIL----GSGHGKPLDWWTLGVFLYEMIYGVTPFKG---RNRRE
                                    . .. . ..|..| ||.||||.     ..||.|  |||.||| .|||  | .||.|    || |
-----------------------------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKE

TFLNILSSQPAFPGD-WTEAS----DLISKLLAKDPTKRLGC-QGGAEEIKSHAFF
.. .|.. .  .... | . |    |||.|.| .|| |||||  ..|||||.|..|
IMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RSK-p3_d-1.AA RSK-Unclassified 21-168 43 2e-58 181.88 In-house 1-148 (283) Show / Hide 
Range on Protein: 21-168
Range on HMM: 1-148/283
Sequence Identity: 43% (64 aa)

FNALKRLGYGDMGTVFLATLRNTGQPLAMKVMNKEVVKARHNQYRVERELEILSMLSHSFTPKLFSHFESKKNIYFVMDYCPGGDMNRLRQRQPEKRFSE
|   . .| ||.| |.|   ..| |  ||||..|. .  .    .|  | .|...  | |  .|.  | ..   | .|.||.|||. |  |   ||.|.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

NAARFYAAEVCLAIEYLHKSGIIYRDLKPENVLIQEDGHIMLTDFDLS
. .||||.|| .| ||||| ..|||||||.|..   .||.||||||||
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLS
Kinase RSK-p3_d-1.AA PDK1 21-165 40 1.4e-54 165.38 In-house 1-154 (307) Show / Hide 
Range on Protein: 21-165
Range on HMM: 1-154/307
Sequence Identity: 40% (62 aa)

FNALKRLGYGDMGTVFLATLRNT----GQPLAMKVMNKEVVKARHN-QYRVERELEILSMLS-----HSFTPKLFSHFESKKNIYFVMDYCPGGDMNRLR
|   | .| |  .||.||. . |    ..  | |. .|.   .|.. .. | || ||.. |.     | .  ||. .| .  ..|||..|||.||.  . 
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYI-IREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYM

QRQPEKRFSENAARFYAAEVCLAIEYLHKSGIIYRDLKPENVLIQEDGHIMLTDF
..|| . |..  .||||||  .|.|.||. ||| |||||||.|...|.|||.|||
KKQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDF
Kinase RSK-p3_d-1.AA RSK-Unclassified 256-355 52 1.5e-51 159.93 In-house 180-283 (283) Show / Hide 
Range on Protein: 256-355
Range on HMM: 180-283/283
Sequence Identity: 52% (55 aa)

QSFVGTEEYVAPEMILGSGHGKPLDWWTLGVFLYEMIYGVTPFKGRNRRETFLNILSSQPAFPGDW---TEASDLISKLLAKDPTKRLGCQGG-AEEIKS
.||.|||||.||||| . ||.|  ||||||. .|||  |..|..| |. ||| ||.  .  || |     .. ||| ||| . | |||||  | |..|| 
NSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKR

HAFF
| ||
HPFF
Kinase RSK-p3_d-1.AA PKA 21-165 41 8.2e-50 171.8 In-house 1-145 (263) Show / Hide 
Range on Protein: 21-165
Range on HMM: 1-145/263
Sequence Identity: 41% (62 aa)

FNALKRLGYGDMGTVFLATLRNTGQPLAMKVMNKEVVKARHNQYRVERELEILSMLSHSFTP-KLFSHFESKKNIYFVMDYCPGGDM-NRLRQRQPEKRF
|. .. || |  |.| |.  ...|.  |||...|. .. .  . .|  |  ||. ..|.|   |. ..|   ...|.||.|.|||.|  .||    ..||
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRK---SGRF

SENAARFYAA-EVCLAIEYLHKSGIIYRDLKPENVLIQEDGHIMLTDF
|.  |.|||| ...||.||||.  |||||||||| || ..||| .|||
SNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDF
Kinase RSK-p3_d-1.AA MAST 259-355 44 9.2e-47 140.49 In-house 229-337 (337) Show / Hide 
Range on Protein: 259-355
Range on HMM: 229-337/337
Sequence Identity: 44% (49 aa)

VGTEEYVAPEMILGSG-HGKPLDWWTLGVFLYEMIYGVTPFKGRNRRE-TFLNILS--SQPAFPGD---------WTEASDLISKLLAKDPTKRLGCQGG
.|| .| ||| ||| | .|||.||| .|. .|| . |..|| | .. | .| ||..      .| .           || |||.|||...| |||| . |
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN-G

AEEIKSHAFF
|.|||.|.||
ADEIKQHPFF
Kinase RSK-p3_d-1.AA SGK 21-168 37 4e-46 140.16 In-house 1-172 (283) Show / Hide 
Range on Protein: 21-168
Range on HMM: 1-172/283
Sequence Identity: 37% (66 aa)

FNALKRLGYGDMGTVFLATLRNT------------------GQPLAMKVMNKEVVK-------ARHNQYRVEREL-EILSMLSHSFTPKLFSHFESKKNI
|  || .| |  | |...    .                  ..  |||| .|. .        ..  |  .  |   ||. ..| |  .|   |  |.  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YFVMDYCPGGDMNRLRQRQPEKRFSENAARFYAAEVCLAIEYLHKSGIIYRDLKPENVLIQEDGHIMLTDFDLS
||||||  ||.|    ||  ||.|.|  |||||||. .|.||||.. ||||||||||.|   .||. |||| |.
YFVMDYVNGGEMFYHLQR--EKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC
Kinase RSK-p3_d-1.AA MAST 21-168 39 1.2e-43 130.85 In-house 1-149 (337) Show / Hide 
Range on Protein: 21-168
Range on HMM: 1-149/337
Sequence Identity: 39% (59 aa)

FNALKRLGYGDMGTVFLATLRNTGQPLAMKVMNKEVVKARHNQYRVERELEILSMLSHSFTPKLFSHFES--KKNIYFVMDYCPGGDMNRLRQRQPEKRF
|. .| .. |  | |.|.  ..|..  ||||.|.     .. .  |  |  ||.|..  |. |.|. |..  ||  ..||.|  ||| . | .     ..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGN-CM

SENAARFYAAEVCLAIEYLHKSGIIYRDLKPENVLIQEDGHIMLTDFDLS
 |. |..| ||  |..||||..||. |||||.|.||  .||| |||| ||
PEWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase RSK-p3_d-1.AA Akt 256-355 44 1.4e-43 137.15 In-house 160-264 (264) Show / Hide 
Range on Protein: 256-355
Range on HMM: 160-264/264
Sequence Identity: 44% (47 aa)

QSFVGTEEYVAPEMILGSGHGKPLDWWT-LGVFLYEMIYGVTPFKGRNRRETFLNILSSQPAFP--GDWT-EASDLISKLLAKDPTKRLG-CQGGAEEIK
..| || || |||...| ||.|. |||. ||...|||..|  ||  ... . | .|....  ||    .  |. ||||.|| |||.||||   ..|.|||
KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIK

SHAFF
.| .|
RHPWF
Kinase RSK-p3_d-1.AA Pkinase 21-183 31 8.2e-43 152.46 Pfam 1-168 (293) Show / Hide 
Range on Protein: 21-183
Range on HMM: 1-168/293
Sequence Identity: 31% (54 aa)

FNALKRLGYGDMGTVFLATLRNTGQPLAMKVMNKEVVKARHNQYRVE-RELEILSMLSHSFTPKLFSHFESKKNIYFVMDYCPGG----DMNRLRQRQPE
.  ....| | .|.|.... ..||.  |.|...|.  |   .|...  .|..|. .|.| .  .|.  ||.|..||.||.||.||    |  .. ... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KRF--SENAARFYAAEVCLAIEYLHKSGIIYRDLKPENVLIQEDGHI----MLTDFDLSVRIEQDRDHHHHPGA
..|  ||. ..||. ... ..||.|. |||.|||||||.|| ..|||     ..|| |.  ..    . . . .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-M
Kinase RSK-p3_d-1.AA SGK 257-355 46 4.3e-42 127.47 In-house 184-283 (283) Show / Hide 
Range on Protein: 257-355
Range on HMM: 184-283/283
Sequence Identity: 46% (46 aa)

SFVGTEEYVAPEMILGSGHGKPLDWWTLGVFLYEMIYGVTPFKGRNRRETFLNILSSQPAFPGDWT-EASDLISKLLAKDPTKRLGCQGGAEEIKSHAFF
.| || || |||.... .|..  ||| || .||||.||  ||  ||. . . ||...   .|   . .|.|||  ||.|||.||||   ...|||.| ||
TFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase RSK-p3_d-1.AA MAST 21-168 39 1.8e-41 131.23 In-house 1-146 (334) Show / Hide 
Range on Protein: 21-168
Range on HMM: 1-146/334
Sequence Identity: 39% (59 aa)

FNALKRLGYGDMGTVFLATLRNTGQPLAMKVMNKEVVKARHNQYRVERELEILSMLSHSFTPKLFSHFESKKNIYFVMDYCPGGDMNRLRQRQPEKRFSE
|.  | .. |  | |.|.  ..|..  ||||..|     .. .  |  |  ||.|..  |. |.|. |..|.....||.|  ||| . | .     .| |
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYG--YFDE

NAARFYAAEVCLAIEYLHKSGIIYRDLKPENVLIQEDGHIMLTDFDLS
. |..| ||. |..||||..||. |||||.|.||  .||| |||| ||
WMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase RSK-p3_d-1.AA MAST 259-355 45 1.3e-40 128.46 In-house 225-334 (334) Show / Hide 
Range on Protein: 259-355
Range on HMM: 225-334/334
Sequence Identity: 45% (50 aa)

VGTEEYVAPEMILGSG-HGKPLDWWTLGVFLYEMIYGVTPFKGRNRRETFLNILSSQ---PAFPGD---------WTEASDLISKLLAKDPTKRLGCQGG
.|| .| ||| ||| | ||||.||| .|. .|| . |..|| . .. |.| |||.       .| .           || |||.|||. || |||| ..|
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

AEEIKSHAFF
|.|.|.| ||
ADEVKQHPFF
Kinase RSK-p3_d-1.AA Akt 21-165 46 2.1e-40 126.84 In-house 1-145 (264) Show / Hide 
Range on Protein: 21-165
Range on HMM: 1-145/264
Sequence Identity: 46% (69 aa)

FNALKRLGYGDMGTVFLATLRNTGQPL-AMKVMNKEVVKARHNQYRVERELEILSMLSHSFTPKLFSHFESKKNIYFVMDYCPGGDMNRLRQRQPEKRFS
|. || || |  | |||.   .|..   ||||  |..  ..     .  |  || .  | |  .|   | .....|||||||.||.   . ||  ..|||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQR--KRRFS

ENAARFYAAEVCLAIEYLHKSGIIYRD-LKPENVLIQEDGHIMLTDF
|. ||||.||. ||||.||...||||| |||||.|. .|||| ||||
EDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDF
Kinase RSK-p3_d-1.AA PKA 260-355 40 5.4e-33 115.93 In-house 160-263 (263) Show / Hide 
Range on Protein: 260-355
Range on HMM: 160-263/263
Sequence Identity: 40% (42 aa)

GTEEYVAPEMILGS-GHGKPLDWWTLGVFLYEMIYGVTPFKGR--NRRETFLNILSSQPAFPGDWTEAS----DLISKLLAKDPTKRLGCQG-GAEEIKS
|| || |||.|... ||||. |||.||.  |||  |..||     .  ...  |.. .  ||   . .     |||.|||..|.|||.|..  |.. || 
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKN

HAFF
| .|
HKWF
Kinase RSK-p3_d-1.AA PDK1 254-355 38 5.3e-31 91.8 In-house 195-307 (307) Show / Hide 
Range on Protein: 254-355
Range on HMM: 195-307/307
Sequence Identity: 38% (44 aa)

KSQSFVGTEEYVAPEMILGSGHGKPLDWWTLGVFLYEMIYGVTPFKGR-----NRRETFLNILSSQPAFPGDWT---EASDLISKLLAKDPTKRLGC---
.. ||||| ||| ||.. ..  ..  | | ||. .| |. | .||.|      |   ||  |.  | .|| .     .|.||..||| .||..||.    
RCKSFVGTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDE

QGGAEEIKSHAFF
 || ..|| | ||
CGGYQQIKAHPFF
Kinase RSK-p3_d-1.AA Pkinase 256-355 29 4.1e-28 100.48 Pfam 169-293 (293) Show / Hide 
Range on Protein: 256-355
Range on HMM: 169-293/293
Sequence Identity: 29% (38 aa)

QSFVGTEEYVAPEMIL-GSGHGKPLDWWTLGVFLYEMIYGVTPFKGR------NRRETFLNILSSQPAFPGDWT----------------------EASD
..|.|| .|.||| |. |...|.. |.| .|. ||||. | .||.|.      . .. . .|.. .. |. .|.                      |. |
TTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

LISKLLAKDPTKRLGCQGGAEEIKSHAFF
.|...|.|||.||..    ||.|. | .|
FIKWCLCKDPKKRPT----AEQILQHPWF
Kinase RSK-p3_d-1.AA TyrKc 21-237 16 3.3e-10 -57.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-237
Range on HMM: 1-280/280
Sequence Identity: 16% (49 aa)

FNALKRLGYGDMGTVFLATLRNTGQPLAMKVMNKEVVKARHNQYRVERELEILSML--SHSFTPKLFSHFESK-------KNIYFVMDYCPGGDMNRLRQ
   .| || |  |.|...|..   .. | |.....       .    ||..|...|  .|    .|.    ..       . .. || |.|.|| .   .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RQPEKRFSENAARFYAAEVCLAIEYLHKSGIIYRDLKPENVLIQEDGHIMLTDFDLSVRIEQD-------RDHH-----HHP------------------
.  .| ..      ..  ..   ||||. ..| |||   |.|. |....  .|| ||  |. |          .     .                    
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

--------------------GAPAPAP----------APQPKQNKMKKLPFM--------CSTPLSVDVGCAARKAVDVKPSHRPTKKIFPSEM
                    . | | .            . || .. . |          |.. .   .    ..  . .|. ||| .   ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-I---MKQCWHEDPEDRPTFSEIHECF
Kinase RSK-p3_d-1.AA Pkinase_Tyr 21-147 28 2e-06 22.38 Pfam 1-137 (270) Show / Hide 
Range on Protein: 21-147
Range on HMM: 1-137/270
Sequence Identity: 28% (40 aa)

FNALKRLGYGDMGTVFLATLR----NTGQPLAMKVMNKEVVKARHNQ---YRVERELEILSML-SHSFTPKLFSHFE-SKKN--IYFVMDYCPGGDM-NR
   .| || |  |.|...|..    ||..| | |.. ||  .| | |       ||..|.. | .|    .|       ..   || || |.|.||. . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LRQR-QPEKRFSENAARFYAAEVCLAIEYLHKSGIIYRDL
||..  ......      ...... . |||.  ..| |||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL