Gene HisK_l-2 (S.moellendorffii)

HisK_l-2

Species: S.moellendorffii
Alias: HisK_l-2
External Links:
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
HisK_l-2.AA Protein None 737 None Fasta, JSON
HisK_l-2.NA RNA None 2214 None Fasta, JSON

Protein domain

Protein domains of HisK_l-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
GAF HisK_l-2.AA GAF 158-228 21 6e-06 22.97 Pfam 1-72 (160) Show / Hide 
Range on Protein: 158-228
Range on HMM: 1-72/160
Sequence Identity: 21% (16 aa)

DRHTILNSTLVELGKALALEECTL--WMPTRNGLEL-QLTHSLRQLSKANVGIVPIHHPTLRQVFSSNRAVVIP
|...||  .. ||...| .. | .  ... ..|.||   .|  .. ...    .|. .. . .|| . ...|.|
DLEEILQTIMQELRQLLGCDRCMIYFFLWDEDGWELYWVAHWGWSDQPQQAR-LPM-GGIWGEVFCTCNPIVVP
GAF HisK_l-2.AA GAF 158-314 13 3.8e-05 16.83 SMART 1-142 (142) Show / Hide 
Range on Protein: 158-314
Range on HMM: 1-142/142
Sequence Identity: 13% (23 aa)

DRHTILNSTLVELGKALALEECTLWMPTR-----NGLELQLTHSLRQLSKANVGIVPIHHPTLRQVFSSNRAVVIPSSSPVA---MTRTHAGKYISGDAV
| ..|..... |... | .. |....  .     ..|.. ...           . |   .  ..|. ..| |.|| ...      .. ..  |      
DLEEICQTIVEEVHQFLQMDRCMIYLFDERQNDHGQLWCHASD----------HFPPD--GICGWVWRTGRPVNIPDVHHDPHFFCWKDWL-RYQ-----

AVRVPLLRMVNFPIVDWPEPAKGPYALLVLILPSDSARRWRIHELELVEVVA----VALSHAAILEESI
        ..  ||.          ..|...   ...|.|  ...|.....|    .|...|...|.. 
-----IRSFLCVPIMND---DGQVWGVLCAHHC-HQPRHWTEEDEEFLQMIANQVAIAIQQAQLYEQLQ
GAF HisK_l-2.AA GAF 278-308 29 0.133319 7.72 Pfam 128-160 (160) Show / Hide 
Range on Protein: 278-308
Range on HMM: 128-160/160
Sequence Identity: 29% (10 aa)

VLILPSDSA-RRWRIHELE--LVEVVAVALSHAA
||.. .  . |.|  |.||  |....|  .. | 
VLCCHHC-PPRHWTEHDLECFLLQMFADQIAIAI
HisKA HisK_l-2.AA HisKA 340-405 43 8.9e-19 68.42 Pfam 1-69 (69) Show / Hide 
Range on Protein: 340-405
Range on HMM: 1-69/69
Sequence Identity: 43% (30 aa)

ACNDFLAVMNHEMRVPMHTIITLSSLLQD-SQLNAEQ--RSMVETILRNSRLLAKLIDDVLDLSKLEDG
| ..||| | ||.| |...|.....|||| . |..||  | ..|||.| .. . .||.|.||.|..| |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA HisK_l-2.AA HisKA 340-405 34 1.8e-18 68.58 SMART 1-89 (89) Show / Hide 
Range on Protein: 340-405
Range on HMM: 1-89/89
Sequence Identity: 34% (31 aa)

ACNDFLAVMNHEMRVPMHTIITLSSLLQD----------SQLNAEQ-------------RSMVETILRNSRLLAKLIDDVLDLSKLEDG
| ..||| | ||.| |...|. ...||||          . |..||             | ..|||.| .. . .||.|.||||..| |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HATPase_c HisK_l-2.AA HATPase_c 452-579 25 4.9e-32 113.67 SMART 1-130 (130) Show / Hide 
Range on Protein: 452-579
Range on HMM: 1-130/130
Sequence Identity: 25% (41 aa)

GDEKRLLQIVLFIIGNAVKFTKD--------------GSITVSACMERPEYSRDPRAPEFLPTQGDSHFYIRIQVKDTGIGLRS------QDIPKLFTKF
||..|| |... ...||.|.|..              | |||..                           ||.|.|.|.|.        .|||..| .|
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPF

VQVNK-------------RSG--PGLGLALCKRFVSLMGGHIWIESEGLGKGSTVTILVKLGK
... .             ..|   ||||..|||.| ..||.||.|       .|.|. ..| .
YRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE-------TTFTFTLPLER
HATPase_c HisK_l-2.AA HATPase_c 452-578 31 9.4e-32 112.74 Pfam 1-120 (120) Show / Hide 
Range on Protein: 452-578
Range on HMM: 1-120/120
Sequence Identity: 31% (45 aa)

GDEKRLLQIVLFIIGNAVKFTKD-GSITVSACMERPEYSRDPRAPEFLPTQGDSHFYIRIQVKDTGIGLRS------QDIPKLFTKFVQVNK-----RSG
||. || |.|. ...||.|.|.  | |||..  .                      ..||.|.|.|.|.        .|||..| .|... .     ..|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--------------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSRRKYGG

--PGLGLALCKRFVSLMGGHIWIESEGLGKGSTVTILVKLG
   ||||..|.|.| ..||.||.|||  |.|.|.|. ..| 
GLTGLGLYICRRIVEQHGGTIWVESEP-GGGTTFTFTLPLE
Kinase HisK_l-2.AA HisK 452-578 22 8.9e-24 82.39 In-house 1-164 (164) Show / Hide 
Range on Protein: 452-578
Range on HMM: 1-164/164
Sequence Identity: 22% (40 aa)

GDEKRLLQIVLFIIGNAVKFTKDG------SITVSA---------------CMERPEYSRDPRAPEFLPTQGDSHF-------YIRIQVKDTGIGLRSQD
 |. |. ||.. .|.||.|||. |      .|....               . . .|             .            .|.|.|.|||.|   ..
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQEN------------M-V--QEQLQQKNLIQISVQDTGCGMPEEQ

IPKLFTKFV--------------QVNK---RSGPGLGLALCKRFVSLMG--------GHIWIESEGLGKGSTVTILVKLG
. |.| .|               . ||   ..| ||||. |.... ..|        ..| ..||  ||||| ....   
QKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSE-VGKGSTFSFYIYNN