Gene RIO2-1 (S.moellendorffii)
RIO2-1
Species: S.moellendorffii
Alias: RIO2-1
External Links:
Annotation:
Sequence
Protein domains of RIO2-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | RIO2-1.AA | RIO2 | 71-324 | 51 | 1e-135 | 457.19 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 71-324 Range on HMM: 1-260/260 Sequence Identity: 51% (134 aa) YRLTNLGYDFLAIKTMVNRGLIVGVGRQIGVGKESDIFEVVAEDGQTLALKLHRLGRTSFRAVKSKRDYLKHRSSFNWLYLSRLAALKEFAFMKALHEHG ||||| |||.||.||. | . || |.||||||||. .. |.|. ..|.||||||||. .| .|||.||| . .|.|||||.| ||..||..|.. . YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQYSWMYLSRLSAMKEYQFMDMLYKRN FPTPKAVDWNRHCVLMTLVPGYPLVQVKELKNPALVFDTVISLIVRLAEHGLIHCDFNEFNLLIDDDEK------VTMIDFPQMVSISHRNAESYFDRDV ||.|| .| ||| | | |. |||. | .. .||. |.| . .|||||.|||||||||||||.||| . ..|||||||||..|.||. |||||| FPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPYVYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCGFIMIDFPQMVSTQHQNAQWYFDRDV DCIYKFFLKRFNYVPGGNARTLQGIDNNVDEDDTRPDFVNLARTAGALDKELAASGFTHQ ||| .|| ||||| | | ||| . || | ||||. . DCIHRFFMKRFNYEPKPFPSMLDTEGFGDGYKYAYPDFFRDIQRTDTLDEEVQASGFNKK |
|||||||||
| Kinase | RIO2-1.AA | RIO | 71-277 | 41 | 9.1e-108 | 364.33 | In-house | 1-236 (276) | Show / Hide |
Range on Protein: 71-277 Range on HMM: 1-236/276 Sequence Identity: 41% (97 aa) YRLTNLGYDFLAIKTMVNRGLIVGVGRQIGVGKESDIFEVVAEDGQ-----------TLALKLHRLGRTSFRAVKSKRD---YLKHRSS-FNWLYLSRLA |..|| .|. .....||||| . || .|||||||||.... |.|. |.|.||.|||||. .| .|| |.||| . ||.|..||. YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW ALKEFAFMKALHEHGFPTPKAVDWNRHCVLMTLVPG-------YPLVQVKELKNPALVFDTVISLIVRLAEHG-LIHCDFNEFNLLIDDDEK------VT | ||...||.|.. |||.|. .| .|| . | . . ||..| .|..|.. |..... ...||..|. |.||||||||....|. . .. AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY MIDFPQMVSISHRNAESYFDRDVDCIYKFFLKRFNY ||||||||...| .|. ||.||..|. || |||.| MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVY |
|||||||||
| Kinase | RIO2-1.AA | RIO1 | 106-279 | 31 | 4.4e-79 | 247.08 | Pfam | 1-195 (200) | Show / Hide |
Range on Protein: 106-279 Range on HMM: 1-195/200 Sequence Identity: 31% (62 aa) DIFEVVA-EDGQ-TLALKLHRLGRTSFRAVKSKRDYLKH----RSSFNWLYLSRLAALKEFAFMKALHEHGFPTPKAVDWNRHCVLMTLVP---GYPLVQ ....... |||. .|.|..|.|.|.|. .| .||| .. .. ||.|..|..| |||...|...|.|.| ||..|||||...| .. |.|. . NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR VKELK--------NPALVFDTVIS--LIVRLAEHGLIHCDFNEFNLLIDDDEKVTMIDFPQMVSISHRNAESYFDRDVDCIYKFFLKRFNY--VP .|.. ... ..| .| ......|.||.|.|..|.|.|..||.|...||.||.|...|..|.....||...| .|| ... . |. LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVM |
|||||||||
| RIO | RIO2-1.AA | RIO | 64-291 | 22 | 2.4e-58 | 201.04 | SMART | 1-253 (253) | Show / Hide |
Range on Protein: 64-291 Range on HMM: 1-253/253 Sequence Identity: 22% (58 aa) DSTKYDGYRLTNLGYDFLAIKTMVNRGLIVGVG--RQIGVGKESDIFEVVA----EDGQTLALKLHRLGRTSFRAVKSKRD-YLKHR---SSFNWLYLSR |. .|..|... ... .....||||| | .. ..|..|||.... ... ..| | | .|...|.|. .. .. . . . . ||....| DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR LAALKEFAFMKALHEHGFPTPKAVDWNRHCVLMTLVPG--YPLVQVKELKNPA-------LVFDTVISLIVRLAEHG-LIHCDFNEFNLLID-----DDE |.| ||| ... ..|.|.| ||...|.|| ..| .. . .| ..|.... ....... ...... . |.|.|..|.|.|.. .|. LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC KVTMIDFPQMVSISHRNAESYFDRDVDCIYKFFLKRFNYVPGGNARTLQGIDN || .||..| |...|. ..... ||...| .|| .. ... . ..| KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG |
|||||||||
| Rio2_N | RIO2-1.AA | Rio2_N | 8-89 | 58 | 1e-50 | 173.48 | Pfam | 1-84 (84) | Show / Hide |
Range on Protein: 8-89 Range on HMM: 1-84/84 Sequence Identity: 58% (49 aa) LRYLSKDEFRVLTAVEMGMKNHEIVPAELIDRIAGLK-TGGAYKNIRTLLRHKLVHH-DSTKYDGYRLTNLGYDFLAIKTMVNR .|||||..|||||||||||.|||.|| ||| .|..|. || .. .. |..|||..| . .||||||||..|||.||..|.|.| MRYLSKEDFRVLTAVEMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR |
|||||||||
| Kinase | RIO2-1.AA | Ciliate-C1 | 93-121 | 23 | 7e-06 | 10.64 | In-house | 1-30 (328) | Show / Hide |
Range on Protein: 93-121 Range on HMM: 1-30/328 Sequence Identity: 23% (7 aa) VGVGRQIGVGKESDIFEVVAEDGQ-TLALK ...|| |. .. | . ....| .|.| MKIMKTIGHGYTCKVFYCKMPNNQKVYAVK |
|||||||||
| Kinase | RIO2-1.AA | APH | 95-178 | 12 | 7.3e-05 | 17.46 | Pfam | 1-62 (248) | Show / Hide |
Range on Protein: 95-178 Range on HMM: 1-62/248 Sequence Identity: 12% (11 aa) VGRQIGVGKESDIFEVVAEDGQ-TLALKLHRLGRTSFRAVKSKRDYLKHRSSFNWLYLSRLAALKEFAFMKALHEHGF--PTPKAVD .|.|. | ... . ....| . .. |.. .... .. .. .|......|..||. |.|. .. WWRPISGGWSNRTYYRTTDD-RPRYVLRR-------------------YPPP-----WWAEELHREHRWLRHLAAHGIPVPVPRVLW |
|||||||||
| Kinase | RIO2-1.AA | Ciliate-C3 | 217-245 | 37 | 0.000121 | 13.01 | In-house | 112-140 (140) | Show / Hide |
Range on Protein: 217-245 Range on HMM: 112-140/140 Sequence Identity: 37% (11 aa) LAEHGLIHCDFNEFNLLIDDDEKVTMIDF | || ..| | |.|| ... .||| LHEHNIVHGDIKFSNILINSKDEIKIIDF |
|||||||||
| Kinase | RIO2-1.AA | RIO3 | 81-273 | 24 | 0.000621 | 8.4 | In-house | 14-227 (254) | Show / Hide |
Range on Protein: 81-273 Range on HMM: 14-227/254 Sequence Identity: 24% (53 aa) LAIKTMVNRGLIVGVGRQIGVGKESDIFEVV-------AEDGQTLA----LKLHRLGRTSFRA----VKSKRDYLKHRSSFNWLYLSRLAALKEFAFMKA | . ||| |.. . | |||| .| || . . .|. . |. .| . | .| . |. | || . LLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIHRMWAEKEMHNLAR LHEHGFPTPKAVDWNRHCVLMTLVPGYPLVQVKELKNPAL--------VFDTVISLIVRLAEHGLIHCDFNEFNLLIDDDEKVTMIDFPQMVSISHRNAE . | | | | .| ..|... |. | ||. | ..|. . | |.| |. |.|.| || .|| | | .| MQRAGIPCPTVVLLKKHILVMSFI-GHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLW-HAGKVWLIDVSQSVEPTHPHGL SYFDRDVDCIYKFFLK .. ||. . .|| | EFLFRDCRNVSQFFQK |
|||||||||
| Kinase | RIO2-1.AA | APH | 221-245 | 31 | 0.003988 | 11.54 | Pfam | 171-199 (248) | Show / Hide |
Range on Protein: 221-245 Range on HMM: 171-199/248 Sequence Identity: 31% (9 aa) GLIHCDFNEFNLLID---DDEKV-TMIDF ...|.||. |...| |...| ||. CWCHGDFHPGNVMWDPRPDGGRVTGVIDW |
|||||||||