CAMK1c-S5_k

Species: S.moellendorffii
Alias: CAMK1c-S5_k
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S5_k.AA Protein None 216 None Fasta, JSON
CAMK1c-S5_k.NA RNA None 651 None Fasta, JSON
CAMK1c-S5_k.kin_dom Protein Kinase Domain None 178 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S5_k.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CAMK1c-S5_k.AA Pkinase 2-168 26 3.7e-29 104.17 Pfam 43-209 (293) Show / Hide
Range on Protein: 2-168
Range on HMM: 43-209/293
Sequence Identity: 26% (49 aa)

RNAEN--EARLMSKLCVCPGVVAFEDFVREREAGRCYGTIVMELCGP-----SLAKRLI--QGGAM--TEEEVAKTIKTLAETFKWMHLRGVVHCDLKHH
... .  |...| .|. .| .| . |....   ...|  .|||.|.      .|. ..   ..|..  .|.|. . .. ...  . .| .|..|.|||  
QTHRRLSEIQIMKRLN-HPNIVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPE

NIFQRLNTTAV-DELVIGDFGTA----SDKQWDMQQYCGTAKYMAPEVVAVKNDGARGRRASYTAAVDMWGLGVIVYKLLSGY
||.   |.  . . . |.||| |      ..  |. .|||  ||||||.          .  |. .||||..|.|.| .|.|.
NILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR--------GGQYYGPKVDMWSCGCILYEMLCGR

Kinase CAMK1c-S5_k.AA CAMK 1-168 20 3.2e-25 77.59 In-house 75-331 (425) Show / Hide
Range on Protein: 1-168
Range on HMM: 75-331/425
Sequence Identity: 20% (52 aa)

MRNAENEARLMSKLCV------CPGVVAFEDFVRERE---------AGRC-------YGTIVM---ELCGP-----SLAKRLIQG---------------
..| ..| ..|.||         | .. . ..   ..           ..       .  .||   |.|        |  ....                
RKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVER

GAMTEEEVAKTIKTLAETFKWMHLRGVVHCDLKHHNIFQRLNTTAVD-------------ELVIGDFGTASDKQW-------------------------
| .||.|... .. ...  . .| ...||.|||  ||    | .  |              . | ||| |  ..                          
GRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEG

-DMQQYCGTAKYMA-PEVVAVKNDGARGRRAS-------YTAAVDMWGLGVIVYKLLSGY
  |. .|||  ||| |||.  |  .. .   .       |. ..||| .||| | .|.||
QKMKTFCGTPEYMAAPEVLNGKGHCNMQ-N-ATDEEKPYYGPKCDMWSCGVILYIMLCGY

Kinase CAMK1c-S5_k.AA MSK 39-167 33 2e-22 72.61 In-house 78-206 (277) Show / Hide
Range on Protein: 39-167
Range on HMM: 78-206/277
Sequence Identity: 33% (46 aa)

IVMELC-GPSLAKRLIQGGAMTEEEVAKTIKTLAETFKWMHLRGVVHCDLKHHNIFQRLNTTAVD--ELVIGDFGTA----SDKQWDMQQYCGTAKYMAP
.|||.| |. |  .. . . ..|.|..  .  |    . || .|..| |||  ||   | .   |  .... ||| |    .|..| |. .|.|  ||||
LVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENI---LFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAP

EVVAVKNDGARGRRASYTAAVDMWGLGVIVYKLLSG
|.... . .  |    | .|.|.|.|||| | .|.|
EMLRRGYAQDGG----YDEACDWWSLGVILYTMLTG

Kinase CAMK1c-S5_k.AA Ciliate-E2 39-216 21 2.7e-22 73.31 In-house 111-363 (365) Show / Hide
Range on Protein: 39-216
Range on HMM: 111-363/365
Sequence Identity: 21% (56 aa)

IVMELC-GPSLAKRLI------------QGGAMTEEEVAKTIKTLAE---------------TFKWMHLRG-VVHCDLKHHNIFQRLNTTAVDELVIGDF
.|||.| | .| ....            . . .||.|... .| ...                .. .| .. ..| |.|  ||.          . | ||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDF

GTASDKQ-------------WDMQQY----------------------CGTAKYMAPEVVAVKNDGARGRRASYTAAVDMWGLGVIVYKLLSGYRSRVEF
|.. . .             | |.                        |||. |||||..  |...    .  |. ..|.| |||| | .|.|..    .
GLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--Q

DFLRAG--AFPSDL-----------------VSCEAEDLIQG----MLAVEQSKRVT-LDAVLAHP
.    .   ||.                   .| |. |||.     || ....|| |  . .| ||
QQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHP

Kinase CAMK1c-S5_k.AA Ciliate-E2a 39-168 33 1.9e-21 59.89 In-house 76-213 (275) Show / Hide
Range on Protein: 39-168
Range on HMM: 76-213/275
Sequence Identity: 33% (48 aa)

IVMELC-GPSLAKRLIQGGAMTEE--EVAKTIKTLA-ETFKWMHLRGVVHCDLKHHNIFQR-LNTTAV--DELVIGDFGTASDKQWD----MQQYCGTAK
.|||.| | .| ....| . ..||  |... .. |  . .  || |...| |||  ||. . ....     ...| |||.| . . |    | | |||. 
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMAPEVVAVKND-GARGRRASYTAAVDMWGLGVIVYKLLSGY
|.|||| . | .      . .|.  .||| .||| | ||.|.
YVAPEVLNNKEVLK----HKQYDTKCDMWSCGVIFYILLCGK

Kinase CAMK1c-S5_k.AA RSK 39-169 27 1.9e-19 68.02 In-house 78-210 (278) Show / Hide
Range on Protein: 39-169
Range on HMM: 78-210/278
Sequence Identity: 27% (38 aa)

IVMELC-GPSLAKRLIQGGA---MTEEEVAKTIKTLAETFKWMHLRGVVHCDLKHHNIFQRLNTTAVDELVIGDFGTASDKQWDMQQ----YCGTAKYMA
..||.| |. | ..| . .    ..|.|..  . ... . . .| .|..| |||  ||     .    .... ||| .  .  |. |    .|.|. |||
LIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMA

PEVVAVKNDGARGRRASYTAAVDMWGLGVIVYKLLSGYR
||....    |  ..  ...|.| | |||. | .|.|..
PEMLKR----AN-QQGGHDKACDWWSLGVLMYEMLTGCP

Kinase CAMK1c-S5_k.AA CAMK1 59-168 35 9e-19 51.14 In-house 106-213 (276) Show / Hide
Range on Protein: 59-168
Range on HMM: 106-213/276
Sequence Identity: 35% (41 aa)

TEEEVAKTIKTLAETFKWMHLRGVVHCDLKHHNIFQRLNTTAVD-ELV--IGDFGTAS--DKQWD-MQQYCGTAKYMAPEVVAVKNDGARGRRASYTAAV
||.. ....| ...  . || .|.||.|||  |.   . .   | ...  | ||| .   | . . |.. |||  |.||||.. |          |  |.
TEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLL--YYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK------DKPYDKAC

DMWGLGVIVYKLLSGY
|||. ||| | || ||
DMWSIGVITYILLCGY

Kinase CAMK1c-S5_k.AA PSK 39-216 29 1.6e-18 55.54 In-house 73-256 (258) Show / Hide
Range on Protein: 39-216
Range on HMM: 73-256/258
Sequence Identity: 29% (57 aa)

IVMEL-CGPSLAKRLIQGGAMTEEEVAKTIKTLAETFKWMHLRGVVHCDLKHHNIFQRLNTTAVDELVIGDFGTASDKQ----WDMQQYCGTAKYMAPEV
.|||.  |  .  |..  |  ||..  .  . ...  ...|  .. | |||  |            ..| ||| |. ..    | |.  |||  | ||||
MVMEMATGGEMFDRIVAKGRFTERDATRVLQMVLDGMRYLHALRITHRDLKPENLLY-YHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEV

VAVKNDGARGRRASYTAAVDMWGLGVIVYKLLSG------------YRSRVEFDFLRAGAFPSDLVSCEAEDLIQGMLAVEQSKRVTLDAVLAHP
           |  || .|||| .||| | |.||            ||  .   .   | . .. ||  | | |  .| ..|..| |  . . ||
LL---------RKPYTQSVDMWAVGVIAYILMSGIMPFDDDCRTRLYRHILTGKYNYYGQPWPS-VSHLAKDFIDKLLEINQGERMTASQAMKHP

Kinase CAMK1c-S5_k.AA S_TKc 1-216 23 9.8e-18 66.16 SMART 18-229 (231) Show / Hide
Range on Protein: 1-216
Range on HMM: 18-229/231
Sequence Identity: 23% (59 aa)

MRNAE---------------NEARLMSKLCVCPGVVAFEDFVREREAGRCYGTIVMELCGP---SLAKRLIQGGA------MTEEEVAKTIKTLAETFKW
 |. .               .| ....|   .| .| . |. ..   .. |  .|||.|.    .| ... . |       ..| .... .. ...  . 
CRHKKTGRIVAIKIIKEHIRREIQILKK--HHPNIVKLYDVFQD---DHLY--MVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEY

MHLRGVVHCDLKHHNIFQRLNTTAVDELVIGDFGTASDKQWDMQQYCGTAKYMAPEVVAVKNDGARGRRASYTA-AVDMWGLGVIVYKLLSGYR----SR
.| .|..|.|||  ||.  |..    .. |.||| |         .|||  ||||||.            .|.  ..|.| .|.|.| .|.||       
CHSHGIIHRDLKPENIL--LDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL------------GYGKCKCDWWSCGCILYEMLCGYPPFPQMQ

VEFDFLRAGAFPSDLVSCEAEDLIQGMLAVEQSKRVTLDAVLA-------HP
. |. ..         | || |.|...| .. .|| |   .|.       ||
MMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

Kinase CAMK1c-S5_k.AA MAPKAPK 39-168 29 1.3e-17 50.66 In-house 78-215 (292) Show / Hide
Range on Protein: 39-168
Range on HMM: 78-215/292
Sequence Identity: 29% (43 aa)

IVME-LCGPSLAKRLIQ--GGAMTEEEVAKTIKTLAETFKWMHLRGVVHCDLKHHNI-FQRLNTTAVDELVIGDFGTASD-------KQW----DMQQYC
.||| . | .| ..  |   .. ||.|... .|  ..  . .| ..  | |||  || ..  |  ..  . ..||| |.         .     ...  |
LVMECMEGGELFQHIQQRGHKHFTEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCP--VKLCDFGFAKEIHLNHDCTTPITTPELMTPC

GTAKYMAPEVVAVKNDGARGRRASYTAAVDMWGLGVIVYKLLSGY
.|. ||||||| .           |    ||| |||| | .|.||
YTPYYMAPEVVGAFK-----EAHTYDKSCDMWSLGVIMYIMLCGY

Kinase CAMK1c-S5_k.AA RSK 39-216 27 2.4e-17 58.61 In-house 78-269 (271) Show / Hide
Range on Protein: 39-216
Range on HMM: 78-269/271
Sequence Identity: 27% (56 aa)

IVMELC-GPSLAKRLIQGGAMTEEEVAKTIKTLAETFKWMHLRGVVHCDLKHHNIFQRLNTTAVDELVIGDFGTASDKQWDMQQY-----CGTAKYMAPE
..|... |  | .||   . ..|.||.    ..| .    |  |.|| |||  ||     .   . . | ||| |  ||   .       |.|| |||||
MIMDFMRGGDLFDRLLKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA--KQLRDENGMLMTFCYTANYMAPE

VVAVKNDGARGRRASYTAAVDMWGLGVIVYKLLSGY-------RSRVEFDFLRAGAFP-------SDLVSCEAEDLIQGMLAVEQSKRVTL-----DAVL
|.         .|  ...|.| | .||. |  |.|.       | . .   .|..           | .| || ||. .|| .   .|..        ..
VL---------KRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIK

AHP
 ||
QHP

Kinase CAMK1c-S5_k.AA CAMK2 67-216 34 3.2e-16 51.27 In-house 104-257 (259) Show / Hide
Range on Protein: 67-216
Range on HMM: 104-257/259
Sequence Identity: 34% (58 aa)

IKTLAETFKWMHLRGVVHCDLKHHNIF--QRLNTTAVDELVIGDFGTASDKQWDMQ---QYCGTAKYMAPEVVAVKNDGARGRRASYTAAVDMWGLGVIV
|. . |. ...| .|.|| |||  |.    ..   ||    . ||| | . | | |    . ||  |..|||.         |.  |  .||.|  |||.
IQQILESVNHCHQNGIVHRDLKPENLLLASKCKGAAVK---LADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL---------RKDPYGKPVDIWACGVIL

YKLLSGYRSRVE------FDFLRAGA--FPS---DLVSCEAEDLIQGMLAVEQSKRVTLDAVLAHP
| || ||    .      .  ..|||  .||   | |  || .||. ||..  .||.| |  | ||
YILLVGYPPFWDEDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHP

Kinase CAMK1c-S5_k.AA CAMK 184-216 45 1.4e-08 23.06 In-house 387-423 (425) Show / Hide
Range on Protein: 184-216
Range on HMM: 387-423/425
Sequence Identity: 45% (17 aa)

SDL----VSCEAEDLIQGMLAVEQSKRVTLDAVLAHP
||     || |. |||..|| |. .|| |.. .|.||
SDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHP

Kinase CAMK1c-S5_k.AA MAPKAPK 185-216 37 4.6e-05 11.13 In-house 259-290 (292) Show / Hide
Range on Protein: 185-216
Range on HMM: 259-290/292
Sequence Identity: 37% (12 aa)

DLVSCEAEDLIQGMLAVEQSKRVTLDAVLAHP
. .|.|| |||  .| .. ..| |  .|..||
SHISEEAKDLIRKLLRRDPTQRLTIEQVMNHP

Kinase CAMK1c-S5_k.AA RSK 187-216 34 0.000263 12.07 In-house 242-276 (278) Show / Hide
Range on Protein: 187-216
Range on HMM: 242-276/278
Sequence Identity: 34% (12 aa)

VSCEAEDLIQGMLAVEQSKRVT-----LDAVLAHP
.| || |||..|| .. .|| .     .. ...||
LSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHP

Kinase CAMK1c-S5_k.AA MSK 187-215 37 0.002787 6.94 In-house 246-274 (277) Show / Hide
Range on Protein: 187-215
Range on HMM: 246-274/277
Sequence Identity: 37% (11 aa)

VSCEAEDLIQGMLAVEQSKRVTLDAVLAH
.| .| ||||..| .  .|| ...  .||
MSPDAKDLIQWLLTKDPKKRLGMNDLRAH

Kinase CAMK1c-S5_k.AA CAMK1 187-216 41 0.018375 2.9 In-house 244-274 (276) Show / Hide
Range on Protein: 187-216
Range on HMM: 244-274/276
Sequence Identity: 41% (13 aa)

VSCE-AEDLIQGMLAVEQSKRVTLDAVLAHP
.| . | |.| .|| |. .|| | . .|.||
ISDQEAKDFIKHMLEVDPKKRYTCEQCLNHP

Kinase CAMK1c-S5_k.AA Pkinase 190-216 37 0.132842 6.75 Pfam 265-291 (293) Show / Hide
Range on Protein: 190-216
Range on HMM: 265-291/293
Sequence Identity: 37% (10 aa)

EAEDLIQGMLAVEQSKRVTLDAVLAHP
|. |.| ..|..  .|| | . .| ||
ECKDFIKWCLCKDPKKRPTAEQILQHP