CAMK1c-S2_g

Species: S.moellendorffii
Alias: CAMK1c-S2_g
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S2_g.AA Protein None 375 None Fasta, JSON
CAMK1c-S2_g.NA RNA None 1128 None Fasta, JSON
CAMK1c-S2_g.kin_dom Protein Kinase Domain None 153 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S2_g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CAMK1c-S2_g.AA RIO2 36-105 52 2.3e-33 111.06 In-house 1-73 (260) Show / Hide
Range on Protein: 36-105
Range on HMM: 1-73/260
Sequence Identity: 52% (38 aa)

YRLTNLGYDFPAIKTMVNRGLIVGVGRQIGVGKESDIFEVVAEDGQTLALKLHRL---SFRAVKSKRDYLKHR
||||| |||. |.||.  |  .  || |.||||||||. .. |.|.  ..|.|||   ||. .| .|||.|||
YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHR

Kinase CAMK1c-S2_g.AA RIO 36-106 39 1.1e-24 81.59 In-house 1-88 (276) Show / Hide
Range on Protein: 36-106
Range on HMM: 1-88/276
Sequence Identity: 39% (35 aa)

YRLTNLGYDFPAIKTMVNRGLIVGVGRQIGVGKESDIFEVVAEDGQ-----------TLALKLHRL---SFRAVKSKRD---YLKHRR
|..|| .|.  ....||||| .  || .|||||||||.... |.|.             |.|.||.   ||. .| .||   |.|||.
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRH

Kinase CAMK1c-S2_g.AA CAMK 149-294 16 1.6e-21 65.5 In-house 1-241 (425) Show / Hide
Range on Protein: 149-294
Range on HMM: 1-241/425
Sequence Identity: 16% (39 aa)

IIGFGGQASVFKVLRRKDG------------QAFAVKTIL------------------------------DNSGDGYFDREDRTLATLG-----YSNAGI
..| |. . |... .....            | .|.| |                               . .    . || . . .|       .   |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IHLEESLPD---------------RLPDRKQVRHLVL---ELCDYN-----LYERIALK---------------GVLSEHEAAKIIAPLGKTLGQVHEEG
|.| |   |                  ....  ..|.   |.|.       |...|  .               | ..|.||....  .   .   |. .
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

FIHCDVKPENVLLADRESNDDC-----------CVPKLCDFG
 .|.| ||||.|| |.....|            .  |..|||
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFG

Rio2_N CAMK1c-S2_g.AA Rio2_N 1-54 46 1.5e-20 71.75 Pfam 29-84 (84) Show / Hide
Range on Protein: 1-54
Range on HMM: 29-84/84
Sequence Identity: 46% (26 aa)

LIDRIPGLK-TGGAYKNIRTLLRHKLVHH-DSTKYDGYRLTNLGYDFPAIKTMVNR
|| .| .|.  || .. .. |..|||..| . .||||||||..|||. |..|.|.|
LIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR

Kinase CAMK1c-S2_g.AA Pkinase 144-294 27 4.1e-19 68.67 Pfam 1-157 (293) Show / Hide
Range on Protein: 144-294
Range on HMM: 1-157/293
Sequence Identity: 27% (46 aa)

YQVKKIIGFGGQASVFKVLRRKDGQAFAVKTI-LDNSGDGYFDR-----EDRTLATLGYSNAGIIHLEESLPDRLPDRKQVRHLVLELCDY-----NLYE
|.....|| |. ..|.|  ....|. .|||.| ...  ..   .     | . .. |.  |  |. | ..  |     |.  ..|.|.|.       |..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPN--IVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFD

RIA--LKGVL--SEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFG
.|    .|..  ||.|. ...  . . |   |..|.||.|.||||.|. ..  .|. || |.||||
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CV-KICDFG

Kinase CAMK1c-S2_g.AA S_TKc 144-369 20 3.8e-16 59.94 SMART 1-231 (231) Show / Hide
Range on Protein: 144-369
Range on HMM: 1-231/231
Sequence Identity: 20% (56 aa)

YQVKKIIGFGGQASVFKVLRRKDGQAFAVKTILDNSGDGYFDREDRTLATLGYSNAGIIHLEESLPDRLPDRKQVRHLVLELCDY---NLYERIALKGV-
|.. ..|| |. ..|.|.  .|.|. .|.| |        . || . |         |..| ..  |      .  ..|.|.||    .|...|  .|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK---HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LSEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFGRAVL--------------RIRGGFRASG------------
     ..| .|..... . . |   |. |.||.|.||||.|| .        . |.|||| | .               .      ..            
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQLTTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

--------PSQGGDEEDIRERDEQWLGRPPRRVLLGWLSDGARDLIRGMTAGDADNRLVIKEILN-------HEWI
        | .  ... . ..                 |. |.|.||..   | ..|. . |.|.       |.|.
YEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CAMK1c-S2_g.AA MAPKAPK 230-294 34 1.3e-12 34.91 In-house 88-151 (292) Show / Hide
Range on Protein: 230-294
Range on HMM: 88-151/292
Sequence Identity: 34% (23 aa)

LYERIAL--KGVLSEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFG
| ..|    ..  .|.||..|.   .. . . |. .  | |.||||.|  |...|   |. ||||||
LFQHIQQRGHKHFTEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHN---CPVKLCDFG

Kinase CAMK1c-S2_g.AA MSK 220-302 35 1.8e-12 38.43 In-house 77-157 (277) Show / Hide
Range on Protein: 220-302
Range on HMM: 77-157/277
Sequence Identity: 35% (30 aa)

HLVLELCDYN-LYERIALKGVLSEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFGRAVLRIRG
.||.|.|  . | ..|  ..  .|.|.. |.. |   . . |..|.|| | ||||.|..|.|.|      || ||| | |. ..
YLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHV---KLIDFGFARLFPQD

Kinase CAMK1c-S2_g.AA DCAMKL 221-294 36 6.8e-12 32.74 In-house 92-164 (279) Show / Hide
Range on Protein: 221-294
Range on HMM: 92-164/279
Sequence Identity: 36% (27 aa)

LVLELCDY-NLYERIALKGVLSEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFG
||.|.  .  |.. |   .  .| .|| ..  |.| |   || . .| |.|||| |. . |.     . ||||||
LVMEYVQGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG-EKSL-KLCDFG

Kinase CAMK1c-S2_g.AA RSK 230-294 33 9.1e-12 39.63 In-house 88-152 (278) Show / Hide
Range on Protein: 230-294
Range on HMM: 88-152/278
Sequence Identity: 33% (23 aa)

LYERIALKGV---LSEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFG
|....  ..    .||.||. ..| . ...   |. |.|| | ||||.|..|.. |.     ||.|||
LFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHI--KLTDFG

Kinase CAMK1c-S2_g.AA CAMK 337-369 39 5.6e-11 30.87 In-house 393-425 (425) Show / Hide
Range on Protein: 337-369
Range on HMM: 393-425/425
Sequence Identity: 39% (13 aa)

WLSDGARDLIRGMTAGDADNRLVIKEILNHEWI
..|. ..||||.|   | ..|. |...|||.|.
FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase CAMK1c-S2_g.AA MAPKAPK 230-294 37 1.3e-10 31.89 In-house 89-152 (268) Show / Hide
Range on Protein: 230-294
Range on HMM: 89-152/268
Sequence Identity: 37% (25 aa)

LYERIALK--GVLSEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFG
|..||  .      | |||.|.   .. . . |.    | |.|||| |. |...|   || ||.|||
LFHRIQERGDQHFTEREAAQIMKQICQAVQHCHSMNIAHRDLKPENLLYKDTQPN---CVLKLTDFG

Kinase CAMK1c-S2_g.AA RSK 230-294 33 2.3e-10 33.45 In-house 88-150 (271) Show / Hide
Range on Protein: 230-294
Range on HMM: 88-150/271
Sequence Identity: 33% (22 aa)

LYERIALKGVLSEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFG
|  |.  ....|| |.. . | . ...   |. | .| | ||||.|..| . | ..   |.||||
LFDRLLKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHI--KICDFG

Kinase CAMK1c-S2_g.AA CAMKL 220-294 31 7e-10 27.57 In-house 97-174 (297) Show / Hide
Range on Protein: 220-294
Range on HMM: 97-174/297
Sequence Identity: 31% (26 aa)

HLVLELCDYN---LYERIALK----GVLSEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFG
.||.|.|.     |...|  .    | ..|||| ..   .   .   |. | .| | ||||.|| .. .|    . |..|||
YLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----NIKIIDFG

Kinase CAMK1c-S2_g.AA MAPKAPK 339-369 45 1.9e-09 24.91 In-house 262-292 (292) Show / Hide
Range on Protein: 339-369
Range on HMM: 262-292/292
Sequence Identity: 45% (14 aa)

SDGARDLIRGMTAGDADNRLVIKEILNHEWI
|. | |||| .   |. .||.|....|| ||
SEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI

Kinase CAMK1c-S2_g.AA DCAMKL 339-369 38 1.3e-08 22.32 In-house 249-279 (279) Show / Hide
Range on Protein: 339-369
Range on HMM: 249-279/279
Sequence Identity: 38% (12 aa)

SDGARDLIRGMTAGDADNRLVIKEILNHEWI
||.|.|||. |  .| . |   ..|. | |.
SDSAKDLISHMLQVDPEKRYTAEQIMQHPWV

Kinase CAMK1c-S2_g.AA CAMKL 338-369 40 4.8e-08 21.62 In-house 267-297 (297) Show / Hide
Range on Protein: 338-369
Range on HMM: 267-297/297
Sequence Identity: 40% (13 aa)

LSDGARDLIRGMTAGDADNRLVIKEILNHEWI
.|  .|||||.|   . . |  |..|.||.| 
VS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase CAMK1c-S2_g.AA RSK 338-369 40 1.2e-07 24.36 In-house 242-278 (278) Show / Hide
Range on Protein: 338-369
Range on HMM: 242-278/278
Sequence Identity: 40% (15 aa)

LSDGARDLIRGMTAGDADNRLV-----IKEILNHEWI
||. |.||||.|   |  .||      ..||..|.|.
LSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase CAMK1c-S2_g.AA DCAMKL 144-173 38 3.6e-07 17.77 In-house 1-31 (279) Show / Hide
Range on Protein: 144-173
Range on HMM: 1-31/279
Sequence Identity: 38% (12 aa)

YQVKKIIGFGGQASVFKVLRRKDG-QAFAVK
||. .||| |  |.|... .|..| ...| |
YQIGRIIGDGNFAVVHECRHRETGDHKYAMK

Kinase CAMK1c-S2_g.AA RSK 338-369 37 5.3e-07 21.29 In-house 235-271 (271) Show / Hide
Range on Protein: 338-369
Range on HMM: 235-271/271
Sequence Identity: 37% (14 aa)

LSDGARDLIRGMTAGDADNRLVI-----KEILNHEWI
.|| | ||.|.|   |  |||       ..|..| |.
ISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF

Kinase CAMK1c-S2_g.AA MAPKAPK 339-369 48 2e-06 17.9 In-house 238-268 (268) Show / Hide
Range on Protein: 339-369
Range on HMM: 238-268/268
Sequence Identity: 48% (15 aa)

SDGARDLIRGMTAGDADNRLVIKEILNHEWI
|. | |||| .   |   || |.|..|| ||
SEDAKDLIRKLLRTDPTERLTIEEFMNHPWI

RIO CAMK1c-S2_g.AA RIO 29-327 15 4e-06 -62.79 SMART 1-253 (253) Show / Hide
Range on Protein: 29-327
Range on HMM: 1-253/253
Sequence Identity: 15% (53 aa)

DSTKYDGYRLTNLGYDFPAIKTMVNRGLIVGVG--RQIGVGKESDIFEVVA----EDGQTLALKLHRLSFRAVKSKRDYLK-HRRICFRVEEYLCPPKKP
|. .|..|...  ...  ....||||| |  ..  ..|..|||.... ...    ..|   | | .|.| .  |... |.. . |.  .           
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHG-----------

QKLHSWLGVNKL--RNEYPALAEKYQ----VKKIIGFGGQASVFKVLRRKDGQAFAVKTILDNSGDGYFDREDRTLATLGYSNAGIIHLEESLPDRLPDR
   ..|. . .|  ..|. .|.. |.    . | | . . . |   . ...  |  .| . ...... | .                             
YHHINWRKMVRLWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKW-----------------------------

KQVRHLVLELCDYNLYERIALKGVLSEHEAAKIIAPLGKTLGQVH---EEG-FIHCDVKPENVLLADRESNDDCCVPKLCDFGRAV----------LR--
                                    . ...  ..   .|.  .|.|    |.|. |    ...| . . |.. .|          |.  
----------------------------------EYYWQIMEYMRKMYHECHLVHADLSEYNMLYHD-LEDENDCKVWIIDWSQSVECDHPMWLEFLERD

---IRGGFRASGPSQGGDEEDI-RERDEQWLG
   |.  ||      | |..|| ||  |  .|
IWNIINFFRR----KGVDCDDIYREIFERITG

Kinase CAMK1c-S2_g.AA RIO1 71-104 28 1e-05 18.26 Pfam 1-39 (200) Show / Hide
Range on Protein: 71-104
Range on HMM: 1-39/200
Sequence Identity: 28% (11 aa)

DIFEVVA-EDGQ-TLALKLHR---LSFRAVKSKRDYLKH
....... |||.  .|.|..|   ..|. .| .||| ..
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFR

Kinase CAMK1c-S2_g.AA MSK 339-369 35 0.000119 11.64 In-house 247-277 (277) Show / Hide
Range on Protein: 339-369
Range on HMM: 247-277/277
Sequence Identity: 35% (11 aa)

SDGARDLIRGMTAGDADNRLVIKEILNHEWI
|  |.|||...   |   ||   ... |||.
SPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK

Kinase CAMK1c-S2_g.AA MAPKAPK 144-180 29 0.00012 9.81 In-house 1-37 (292) Show / Hide
Range on Protein: 144-180
Range on HMM: 1-37/292
Sequence Identity: 29% (11 aa)

YQVKKIIGFGGQASVFKVLRRKDGQAFAVKTILDNSG
   |...| |  ..| .   .. || .||| ..|  |
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQPG

Kinase CAMK1c-S2_g.AA Pkinase 309-369 17 0.000328 15.97 Pfam 211-293 (293) Show / Hide
Range on Protein: 309-369
Range on HMM: 211-293/293
Sequence Identity: 17% (15 aa)

PSQGG----DEEDIRERDEQWLGRPPRRVLLGWLS-------------------DGARDLIRGMTAGDADNRLVIKEILNHEWI
| .|     .  | ... .. .|.|...    | |                   . ..|.|... . |   |. ...||.|.|.
PFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase CAMK1c-S2_g.AA TyrKc 144-369 15 0.000583 -158.59 SMART 1-280 (280) Show / Hide
Range on Protein: 144-369
Range on HMM: 1-280/280
Sequence Identity: 15% (45 aa)

YQVKKIIGFGGQASVFK-VLRRKDGQAFAVKTILDNSGDGYFDREDRTLATLGYSNAGIIHLEESLPDRLPD-RK----QVRHLVLELCDY-NLYERI-A
 . .|..| |    |.| ...    .  |||.. ...    | || | .  || ..  |. |   .   . . |.    .   .|.|.... .| ... .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRL---YGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LKGVLSEHEAAKIIAPLGKTLGQVHEEGFIHCDVKPENVLLADRESNDDCCVPKLCDFG--RAVLRI-RGGFRASGPSQG-----GDE----------ED
 .. |.  .  ..     .     |. ..|| |    |.|....       . | .|||  |..    . |  .|.         |            | 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPEC

IRER----------------------DEQWLG-----RPPRRVLLGWLSDGARDLIRG--------MTAG-----------DADNRLVIKEILNHEWI
|...                      .. . |      ....|.    . . ..            ...            |...|   .||  || .
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase CAMK1c-S2_g.AA MAPKAPK 144-177 26 0.01556 4.22 In-house 1-34 (268) Show / Hide
Range on Protein: 144-177
Range on HMM: 1-34/268
Sequence Identity: 26% (9 aa)

YQVKKIIGFGGQASVFKVLRRKDGQAFAVKTILD
   |...| |    | ..  .. .| || |  .|
QIWKQVLGIGINGKVMQCYHKRTQQKFALKVLRD

Kinase CAMK1c-S2_g.AA CAMKL 144-175 30 0.023256 3.17 In-house 1-33 (297) Show / Hide
Range on Protein: 144-175
Range on HMM: 1-33/297
Sequence Identity: 30% (10 aa)

YQVKKIIGFGGQASVFKVLR-RKDGQAFAVKTI
|.. | .| |. . |   .  |  |.  |.| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKII

Kinase CAMK1c-S2_g.AA MSK 147-173 30 0.073243 2.07 In-house 1-30 (277) Show / Hide
Range on Protein: 147-173
Range on HMM: 1-30/277
Sequence Identity: 30% (9 aa)

KKIIGFGGQASVF---KVLRRKDGQAFAVK
.|  | ||. ..|   |. ....|...|.|
LKVLGTGGYGKFFICRKCVHHDTGKLYAMK