Gene CRK7_c (S.moellendorffii)

CRK7_c

Species: S.moellendorffii
Alias: CRK7_c
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7

Sequence

Name Sequence Type Origin Length Description Download
CRK7_c.AA Protein None 121 None Fasta, JSON
CRK7_c.NA RNA None 366 None Fasta, JSON
CRK7_c.kin_dom Protein Kinase Domain None 91 None Fasta, JSON

Protein domain

Protein domains of CRK7_c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CRK7_c.AA CDK 1-91 47 1.2e-55 176.4 In-house 125-230 (284) Show / Hide 
Range on Protein: 1-91
Range on HMM: 125-230/284
Sequence Identity: 47% (50 aa)

HTRGVLHRDIKGSNLLIDNSGI-----LKIADFGLATFYH-PYQ---NL-ALTSRVVTLWYRPPELLLGATEYS--VGVDLWSTGCILAELLA---GKPI
| ....|||.| .|.||.| |.     |||||||||  .. | |   .. ..|..|||||||.||||||...||   ..|.|| |||.||..    .||.
HSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPL

MPGRTE
.||..|
FPGDSE
Kinase CRK7_c.AA CDK7 5-105 52 1e-49 130.3 In-house 123-222 (288) Show / Hide 
Range on Protein: 5-105
Range on HMM: 123-222/288
Sequence Identity: 52% (53 aa)

VLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELLAGKPIMPGRTEVCSLVFVLRCLVT
.||||.|  |||..  |.||||||||| || .  | ..|. ||| ||| |||| ||  | .|||.|| |||.|||.   |..||  ..  |. . . | |
ILHRDLKPNNLLMNENGQLKIADFGLARFY-GSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGT

P
|
P
Kinase CRK7_c.AA CMGC 1-91 31 2.1e-48 156.65 In-house 199-348 (513) Show / Hide 
Range on Protein: 1-91
Range on HMM: 199-348/513
Sequence Identity: 31% (47 aa)

HTRG--VLHRDIKGSNLLIDNS--------------------GILKIADFGLATFYHPYQNL--------------------ALTSRVVTLWYRPPELLL
| ..  ..|||.| .|.||..                     |.|||.|||||..|||...                     ..|..|||.|||.||.||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GATEYS---------VGVDLWSTGCILAELLAG--------KPIMPGRTE
|...|.          ..| || |||.||.. |        ||. ||..|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSE
Kinase CRK7_c.AA CRK7 1-91 39 3.4e-46 157.22 In-house 129-258 (343) Show / Hide 
Range on Protein: 1-91
Range on HMM: 129-258/343
Sequence Identity: 39% (51 aa)

HTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQ-NLALTSRVVTLWYRPPELLLGATEY------------------------------------
| ...||||||.||.|..|.|..||||||||  |..      .| ||.||||||||||||...|                                    
HKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFK

--SVGVDLWSTGCILAELLAGKPIMPGRTE
     .| ||.||||.||. .||| .|. |
KSGPEIDMWSCGCILGELFTKKPIFQGNNE
Kinase CRK7_c.AA CDC2 1-88 51 5.7e-43 129.57 In-house 120-211 (301) Show / Hide 
Range on Protein: 1-88
Range on HMM: 120-211/301
Sequence Identity: 51% (47 aa)

HTRGVLHRDIKGSNLLIDNSGILKIADFGLA-TFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAEL---LAGKPIMPG
|.|...|||.| .|.|||..| .|||||||| .|  |  ..     |||||||.||.|||.  ||..||.|| |||.||.      ||. .|
HQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHG
Kinase CRK7_c.AA CDK-DD1 1-88 48 3.4e-41 124.57 In-house 115-202 (379) Show / Hide 
Range on Protein: 1-88
Range on HMM: 115-202/379
Sequence Identity: 48% (43 aa)

HTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELLAGKPIMPG
|  |. ||||| .|||| | | |||.|||..| |       . ..||.|||||||||.| . |   .|.|| |||| |.. .  ...|
HNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSHQVVSLWYRPPELLMGSCQYGPEIDMWSVGCILMEMITNFYMFAG
Kinase CRK7_c.AA PITSLRE 1-92 52 8.7e-40 138.5 In-house 123-213 (295) Show / Hide 
Range on Protein: 1-92
Range on HMM: 123-213/295
Sequence Identity: 52% (49 aa)

HTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQN-LALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELLAGKPIMPGRTEV
|   ..||| | ||||. ..|||||.|||||  |   ..  ..|. ||||||| ||||||. .||  ||.|| |||.||.. .||...|. |.
HDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYG--SPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSEI
Kinase CRK7_c.AA CDK-Unclassified 1-92 45 7.6e-39 125.33 In-house 138-245 (324) Show / Hide 
Range on Protein: 1-92
Range on HMM: 138-245/324
Sequence Identity: 45% (49 aa)

HTRGVLHRDIKGSNLLIDNSG-----ILKIADFGLATFYH----------PYQ-NLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELLAGKP
|  .  ||||| .|..|.| .     .|||||||.| ||           |   .   .. |.| ||| ||||.|  .|  ||| || |||.||.. |||
HCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKP

IMPGRTEV
| .||||.
IFQGRTEI
Kinase CRK7_c.AA CCRK 1-106 51 7.6e-37 124.71 In-house 116-221 (285) Show / Hide 
Range on Protein: 1-106
Range on HMM: 116-221/285
Sequence Identity: 51% (55 aa)

HTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELLAGKPIMPGRTEVCSLVFVLR
|   ..|||.|  |||| .|| |||||||||  . . .    |  | | ||| |||| || .|  |||||. |||. ||| . || ||. ..  | .|||
HENNIMHRDLKPANLLISESGHLKIADFGLARVFSNDEGRQYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNNSPIFPGENDIEQLCCVLR

CLVTPA
 | ||.
ILGTPT
Kinase CRK7_c.AA MAPK 1-89 40 1.7e-36 123.61 In-house 134-238 (328) Show / Hide 
Range on Protein: 1-89
Range on HMM: 134-238/328
Sequence Identity: 40% (42 aa)

HTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQN-------------LALTSRVVTLWYRPPELLLG--ATEYSVGVDLWSTGCILAELLA-GKP
|  .|.|||.| ||.|..  . |||.|||||   .| ..               .|  |.| ||| ||..|.  ...|. .|| || |||.||.|  .||
HSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKP

IMPGR
. ||.
LFPGK
Kinase CRK7_c.AA Pkinase 1-100 40 2.9e-33 118.69 Pfam 125-229 (293) Show / Hide 
Range on Protein: 1-100
Range on HMM: 125-229/293
Sequence Identity: 40% (44 aa)

HTRGVLHRDIKGSNLLIDNSGIL----KIADFGLATFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELLAGKPIMPGR----TEV
| .|..|||.| .|.|||| | .    ||.||||| ..  | |  .|....|.||..||...|...|.  || || ||||.|.| |.|. ||.    . .
HSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-H

CSLVFVLR
. .. . |
DQMQMICR
Kinase CRK7_c.AA S_TKc 1-107 17 1e-06 -80.06 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-107
Range on HMM: 19-231/231
Sequence Identity: 17% (39 aa)

HTRG--------------------------------------------------------------------------------------------VLHR
. ..                                                                                            ..||
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIHR

DIKGSNLLIDNSGILKIADFGLATFYHPYQNLALTSRVVTLWYRPPELLLGATEYSV-GVDLWSTGCILAELLAGKPIMPGRTEVC---------SLVFV
|.| .|.|.|.   .||.|||||...        |. ..|.||..||.|     |.   .| || ||||.|.|.|.|  |  ..            . |.
DLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIGSPEAKDFI

LRCLV--------------------TPAF
 .||.                     | |
RKCLQKDPEKRPTAEALQDEWDIKCHPWF