Gene CRK7a (S.moellendorffii)

CRK7a

Species: S.moellendorffii
Alias: CRK7a
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7

Sequence

Name Sequence Type Origin Length Description Download
CRK7a.AA Protein None 706 None Fasta, JSON
CRK7a.NA RNA None 2121 None Fasta, JSON
CRK7a.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of CRK7a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CRK7a.AA CDK 122-406 40 8e-131 420.85 In-house 1-284 (284) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-284/284
Sequence Identity: 40% (128 aa)

FEKLDKIGQGTYSNVYKARDLDSG-----KVVALKKVRFDSL----EPESVKFMA-REIQILRRLDHPNVVKLEGLVTSR-MS--------SSLYLVFEY
.|||.|||.|||  ||||||...|     ..|||||.| ..     | | . . | ||| .|. | |||.|||   ...  |.        ..||.||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MEHDLAGLAACPGIMFTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGI-----LKIADFGLATFYH-PYQ---NL-ALTSRVVTLWYRPPE
|.|||...            .|||..||.|||..|| ....|||.| .|.||.| |.     |||||||||  .. | |   .. ..|..|||||||.||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLLGATEYS--VGVDLWSTGCILAELLA---GKPIMPGRTEVEQLHKIFKLCGSPSEEYWK-KSKLPHATIFKPQQPYKRCIADTYKDFPSTALALLDIL
||||...||   ..|.|| |||.||..    .||..||..| .||.|||..||.|.|. |   .|||.                           ||. .
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKM

LAIEPADRGTAAGALKADFF
|. .|. | .|  ||. ..|
LCYDPKKRISAEQALQHPYF
Kinase CRK7a.AA CMGC 122-406 23 3.8e-115 380.03 In-house 1-513 (513) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-513/513
Sequence Identity: 23% (123 aa)

FEKLDKIGQGTYSNVYKARD--------------LDSGKVVALKKVRFDSLEPESVK----------FMAREIQILRRL-----------------DHPN
.|...|||.|||..|||.||               .....||.||.. .  ..|  |             |||.||..|                 .|.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVKLEGLVTSRMSS---------------SLYLVFEYMEHDLAGLAACPG--------IMFTEPQ------------VKCYL------QQLIRGLD--HC
.|||   .... |                .||||||||.|||...             . ..| .            .|...      .|..|||.  .|
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HTRG--VLHRDIKGSNLLIDNS--------------------GILKIADFGLATFYHPYQNL--------------------ALTSRVVTLWYRPPELLL
| ..  ..|||.| .|.||..                     |.|||.|||||..|||...                     ..|..|||.|||.||.||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GATEYS---------VGVDLWSTGCILAELLAG--------KPIMPGRTE-----------VEQLHKIFKLCGSP----------------SEEYWKKSK
|...|.          ..| || |||.||.. |        ||. ||..|           ..||.||||..|.|                .||. ...|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

LPHA----------------TIF----------KPQQPYK--RCIADTYKD--------------------------------FPSTALALLDILLAIEP
||.                 ..|          .|..|.|  . .   ...                                 .. |. ||. .| ..|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

ADRGTAAGALKADFF
..| ||. ||. ..|
DKRITAEQALQHPYF
Kinase CRK7a.AA CRK7 122-406 39 7.50000000001e-114 384.53 In-house 1-343 (343) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-343/343
Sequence Identity: 39% (136 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVRFDSLEPESVK---F---MAREIQILRRLDHPNVVKLEGLVTS--------RMSSSLYLVFEYMEHDL
.|... || |||  ||||.... |. |||||||   .. | .|   |     ||| ||| |.|.|.|.|   ||.        .   | |.||||| |||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVR---MDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDL

AGLAACPGIM-FTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQ-NLALTSRVVTLWYRPPELLLGATEY-----
.||   . .  | . |.||.. ||  |.| || ...||||||.||.|..|.|..||||||||  |..      .| ||.||||||||||||...|     
MGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHI

---------------------------------SVGVDLWSTGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPSEEYW-KKSKLPHATIFKPQQPYKR
                                    .| ||.||||.||. .||| .|. | .|| ||.|.||||  . |    |||    .||.. |.|
LKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNR

CIADTYK------DFPSTALALLDILLAIEPADRGTAAGALKADFF
 .            .|. .| ||| .|.  |  | ||  .|  |.|
RLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CRK7a.AA CDK7 122-406 37 1.7e-107 287.38 In-house 1-288 (288) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-288/288
Sequence Identity: 37% (110 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVR---FDSLEPESVKFMA-REIQILRRLDHPNVVKLEGLVTSRMSSSLYLVFEYMEHDLAGLAACPGIM
.||...|| |.. .||||.|. .|..|| ||..     |     . . | ||| ||. . |.||. |      .  |...|||..|. ||        | 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHK--SNIQLVFDFMDWDLEVVIKDKSII

FTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELL
.|   .| |  .. .|| .||   .||||.|  |||..  |.||||||||| || .  | ..|. ||| ||| |||| ||  | .|||.|| |||.|||.
LTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFY-GSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELM

AGKPIMPGRTEVEQLHKIFKLCGSPSEEYW-KKSKLPHATIFKPQQPY-KRCIADTYKDFPSTALALLDILLAIEPADRGTAAGALKADFF
   |..||  .. || .||.  | |.|| |   ....   .||.. .| .    . .   .  .| |.  ... .|  | |.. .|| ..|
LRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CRK7a.AA CDC2 122-406 38 2.1e-102 315.57 In-house 1-301 (301) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-301/301
Sequence Identity: 38% (118 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVRFDSLEPE-SV-KFMAREIQILRRLD-HPNVVKLEGLVTSRMSSSLYLVFEYMEHDLAGLAA---CPG
..|. ||| |||  |||..|......|||||.| .. . .  |     ||| .|  |. |||.|||.  . .   ..||.||||...||  .      ..
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

IMFTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLA-TFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILA
  ...  || |. |...|...||.|...|||.| .|.|||..| .|||||||| .|  |  ..     |||||||.||.|||.  ||..||.|| |||.|
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EL---LAGKPIMPGRTEVEQLHKIFKLCGSPSEEYWKK-SKLP-HATIF---KPQQPYKRCIADTYKD----FPSTALALLDILLAIEPADRGTAAGALK
|.      ||. .|  | .|| |||.  |.|.|. |   ..||   . |   |||.. | |     |      . ... ||. .|...|..| .|  ||.
EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

ADFF
  .|
HPYF
Kinase CRK7a.AA S_TKc 122-406 29 2.9e-94 320.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-231/231
Sequence Identity: 29% (89 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVRFDSLEPESVKFMAREIQILRRLDHPNVVKLEGLVTSRMSSSLYLVFEYMEH---DLAGLAACPGIM-
.|.|.|||.|... |||.|. ..|..||.|...         . . ||||||.. .|||.||| .   .   ..||.|.||...   ||  .    |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQNLALTSRVVTLWYRPPELLLGATEYSV-GVDLWSTGCI
    |.| ....|..|....|..|| .|..|||.| .|.|.|.   .||.|||||...        |. ..|.||..||.|     |.   .| || |||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

LAELLAGKPIMPGRTEVEQLHKIFKLCGSPSEEYWKKSKLPHATIFKPQQPYKRCIADTYKDFPSTALALLDILLAIEPADRGTAAGALK-------ADF
|.|.|.|.|  |      |....||..|                                   .. |. ... .|  .|..| ||  ||.         .
LYEMLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

F
|
F
Kinase CRK7a.AA CDK5 122-406 41 1e-91 290.03 In-house 1-287 (287) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-287/287
Sequence Identity: 41% (121 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVRFDSLEPESVKFMA-REIQILRRLDHPNVVKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAACPGIMFT
.||..||| |||  |||||. ... .||||.|| || | | |   | ||| .|. | |.|.| |   . |     | ||||..  ||   .  | |    
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDS-EDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEK--KLTLVFEFCDQDLKKYMDSCNG-EMD

EPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLA-TFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELL-
 . .| .. || .||  || . ||||| |  ||||   |.|| ||||||  |  | ..   .. |||||||||  |.|.  ||  .|.|| |||.||.  
MHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRC--YSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMAN

AGKPIMPGRTEVEQLHKIFKLCGSPSEEYW-KKSKLPHAT---IFKPQQPYKRCIADTYKDFPSTALALLDILLAIEPADRGTAAGALKADFF
||.|  ||  . .|| .|||. |.|.|. |   .|||         |  | .   .   .   .. . ||  .| ..|. | .|. ||.  .|
AGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CRK7a.AA PITSLRE 122-406 40 2.2e-91 309.88 In-house 1-295 (295) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-295/295
Sequence Identity: 40% (120 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVRFD-SLEPESVKFMA-REIQ-ILRRLDHPNVVKLEGLVTSRMSSSLYLVFEYMEHDLAGLAACPG---
|..|..|. |||  ||.|.|   . .||||..  .   | |     . |||. ||. | |||.|..   |      . |.|.||.||||..|        
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

IMFTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQN-LALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILA
  |.....|| .||| || .| |   ..||| | ||||. ..|||||.|||||  |   ..  ..|. ||||||| ||||||. .||  ||.|| |||.|
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYG--SPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFA

ELLAGKPIMPGRTEVEQLHKIFKLCGSPSEEYW-KKSKLPHATIFK--PQQPYKRCIADTY--KDFPSTALALLDILLAIEPADRGTAAGALKADFF
|.. .||...|. |..|...|||. | |.|  |   ..|||.  ..  |..||          .    |.. ||  .|   |. | ||  ||| ..|
EFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase CRK7a.AA CDK10 122-406 42 2.8e-88 299.61 In-house 1-285 (285) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-285/285
Sequence Identity: 42% (121 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVRFDSLEPESVKFMAREIQILRRLDHPNVVKLEGLVTSRMSSSLYLVFEYMEHDLAGLAACPGIMFTEP
|||| ..| |||  ||.|||  |  .||||||| |           |||..| .. |.|.|.|   |  .   |..|| .| | ||| |       ||| 
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQPFTET

QVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELLAGKP
||||   |..|||   | . ..|||.| ||||.   | .|.||||||  |       .| ..|||||| ||||||...    .|.|  ||||.|||..||
QVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYG-VPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKP

IMPGRTEVEQLHKIFKLCGSPSEEYWKK-SKLPHATIFK-PQQPYKRCIADTYKDFPSTALALLDILLAIEPADRGTAAGALKADFF
.|||  |. |.  | .| |.|||. |   |.|| .  |   .|||   .   ..    . . ||..|.  .|  | ||  .|.. .|
LMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYN-NLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase CRK7a.AA Pkinase 122-406 30 7.1e-80 276.46 Pfam 1-293 (293) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-293/293
Sequence Identity: 30% (93 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVRFDSLEPESVKFMAR--EIQILRRLDHPNVVKLEGLVTSRMSSSLYLVFEYMEH-----DLA----GL
.... |||.|... |||... ..||.||.|... .. ...  .  .|  ||||..||.|||.|.| . ...  ....|.|.||.|.     ||.    . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

AACPGIMFTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGIL----KIADFGLATFYHPYQNLALTSRVVTLWYRPPELLLGATEYSVGVDL
. .. . |.| ..|.|. |..|||..|| .|..|||.| .|.|||| | .    ||.||||| ..  | |  .|....|.||..||...|...|.  || 
RHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSTGCILAELLAGKPIMPGR----TEVEQLHKIFK-LCGSPSEEYWKKSKLPHATIFKPQQPYKRCIADTYKDFPSTALALLDILLAIEPADRGTAAGAL
|| ||||.|.| |.|. ||.    . ..|...|.. ... .........  .  . |.. .   .      .  ..... ... .|.  |..| ||. .|
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQIL

KADFF
. ..|
QHPWF
Kinase CRK7a.AA PFTAIRE 122-406 38 5e-72 245.59 In-house 1-287 (287) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-287/287
Sequence Identity: 38% (114 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVRFDSLEPESVKFMA-REIQILRRLDHPNVVKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAACPGIMFT
.|||.| | |.|  |||..    ...|||| .| .  . | . | | ||   |. | | |.| |   .  .    | .||||.. ||.  .  .|| |  
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ--QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKE--TLTFVFEYVHTDLCQYMDKHPGGMHP

EPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYH-PYQNLALTSRVVTLWYRPPELLLGATEYSVGVDLWSTGCILAELLA
.  |. .| ||.|||  || | |||||.|  |||| . | || ||||||     | .     . |||||||||  |||.||||  .|.|  |||. |...
N-NVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSH--TYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMW

GKPIMPGR-TEVEQLHKIFKLCGSPSEEYWKK-SKLPHATIFKPQ--QPYKRCIADTYKDFP--STALALLDILLAIEPADRGTAAGALKADFF
|.|  ||  .  .|| ||||. |.| |. |   ..||.    . .   .  .     .        |  |.  .| .|| ||  |. |.. ..|
GQPAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase CRK7a.AA CDK9 122-347 42 3.3e-69 236.23 In-house 1-250 (340) Show / Hide 
Range on Protein: 122-347
Range on HMM: 1-250/340
Sequence Identity: 42% (107 aa)

FEKLDKIGQGTYS-----------NVYKARDLDSGKVVALKKVRFDSLEPESVKFMA-REIQILRRLDHPNVVKL------EGLVTSRMSS--SLYLVFE
.||| ||||||.             |.|||    ...||.|||  .  | |     | |||..|  | |.||| |          . |  .  ..||||.
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMEN-EKEGFPITALREIKMLQLLKHENVVNLIEICRTKATAYNRYKDRATFYLVFD

YMEHDLAGLAACPGIMFTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPYQNLALTS-----RVVTLWYRPPELLLG
. |||||||   . . |.   .|  .|.|. ||   |   .|||| |  | ||   |||| ||||||  .   .| |        |||||||||||||||
FCEHDLAGLLSNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLG

ATEYSVGVDLWSTGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPSEEYW
  .|   .|.|  |||.||.    ||| | ||  ||  | .||||  .. |
DRNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVW
Kinase CRK7a.AA Pkinase_Tyr 122-205 29 2.1e-18 62.97 Pfam 1-91 (270) Show / Hide 
Range on Protein: 122-205
Range on HMM: 1-91/270
Sequence Identity: 29% (27 aa)

FEKLDKIGQGTYSNVYKARDL----DSGKVVALKKVRFDSLEPE--SVKFMAREIQILRRL-DHPNVVKLEGLVTSRMSS-SLYLVFEYMEH
 ... |.|.| . .|||..      . .  || |... .. ...  . .||. |..|.. | .|||.|.| | .|..  . ..|.|.|||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH
Kinase CRK7a.AA TyrKc 122-406 17 3.1e-13 -8.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 122-406
Range on HMM: 1-280/280
Sequence Identity: 17% (59 aa)

FEKLDKIGQGTYSNVYKARDLDSGKVVALKKVRFDSLEPESVKFMAREIQILRRL--DHPNVVKLEGLVTSR-----MSSSLYLVFEYMEH--------D
 ....|.| | .  |||..       || |... |.     .. . ||..|...|  .|||.|.| | .|.       .  |..|.|||.|        .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LAGLAACPGIMFTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLATFYHPY-------QNLAL----TSR-VVTLWYRPPELL
  .        .. ..   .  |  .| .. | ... |||.   | |... .. ||.||||. . . .       .         .. .. .   .|| .
HRPK-------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

LGATEYSVGVDLWSTGCILAELLAG----KPI-----MPGRTEVEQLHKIFKLCGSPS----EEYWKKSKLPHATIFKPQQPYKRCIADTYKDFPSTALA
    ...   | || |  . |..       |      |. .  .|.. . . .   |.                                   |.    .
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------------FVCCPDE

LLDILL---AIEPADRGTAAGALKADFF
. .| .   . .|.|| | .     ..|
MYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CRK7a.AA CDK9 378-406 41 1.1e-08 25.79 In-house 312-340 (340) Show / Hide 
Range on Protein: 378-406
Range on HMM: 312-340/340
Sequence Identity: 41% (12 aa)

TALALLDILLAIEPADRGTAAGALKADFF
.|. |.|.||.| |. | ... ||  |.|
QACHLIDKLLNIDPKKRMDSDEALDHDWF
Kinase CRK7a.AA Pkinase_Tyr 218-268 29 0.004661 10.98 Pfam 108-158 (270) Show / Hide 
Range on Protein: 218-268
Range on HMM: 108-158/270
Sequence Identity: 29% (15 aa)

FTEPQVKCYLQQLIRGLDHCHTRGVLHRDIKGSNLLIDNSGILKIADFGLA
.| ..  .. .|  .|... . ..  |||.   | |...... ||.|||||
LTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA