Gene CLK_d (S.moellendorffii)

CLK_d

Species: S.moellendorffii
Alias: CLK_d
External Links:
Annotation:

Classification

Group: CMGC
Family: CLK

Sequence

Name Sequence Type Origin Length Description Download
CLK_d.AA Protein None 372 None Fasta, JSON
CLK_d.NA RNA None 1119 None Fasta, JSON
CLK_d.kin_dom Protein Kinase Domain None 344 None Fasta, JSON

Protein domain

Protein domains of CLK_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CLK_d.AA CLK 25-368 42 3.2e-174 527.41 In-house 1-350 (350) Show / Hide 
Range on Protein: 25-368
Range on HMM: 1-350/350
Sequence Identity: 42% (156 aa)

YKVISKMGEGTFGRVLECWDRKY-QEFVAVKVIRNVPKYREAALIEID-VLRALRKH-DKNGKRG--CLQMKEWFDY-RNHVCIVSEKLGPSLYDFLKKN
|..... ||||||.|.||||.|.   .||.|.|||| |||||| .||. ..... .  |.|.|.   |..| .||||  .|.||| |..| |.|||.|.|
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

S------YRPFSIEHVRDIGWQLLNSVAYLHELSLIHTDLKPENILLVSS-----AYVKTLDYKVA-HFVRSFLVLLTLFPLQSARPDKHLTRTPTSAEI
.      |.|. |.|.| ...||...|  ||...|.|||||||||..|.|     ..  ... |                  .|    .   ... . .|
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKIN-------------KKS-NNCVCHYWHVKNTHI

RLIDFGSAT---FENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILG-PISRRIIDNVD--RKAQKYFK
..|||||||   |.. ||| |||||.|||||.|||||||. || ||.||||.|| .|. |||||.|.|||||||||.| ||  . |   .  .  ||||.
CVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKYFY

NGRELNWPDAASSLESIRTVKRLPRLKELVQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
..|... .. ...  ... .| | ....  . . ||   .| ||.. .| |  | |.|.|.|| ||||
HNRLDWDWHNSDGRYVMENCKPLKQYMD--CKDPEH--RQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase CLK_d.AA CMGC 25-368 19 1.2e-103 341.53 In-house 1-513 (513) Show / Hide 
Range on Protein: 25-368
Range on HMM: 1-513/513
Sequence Identity: 19% (106 aa)

YKVISKMGEGTFGRVLECWD--------------RKYQEFVAVKVIRNVPKYREAAL-------------IEIDVLRALR-KHDKNG---------KRG-
|..|.| ||||.| | .|.|              ....|.||.| |.|.. | | |.              ||  |. |. .||. .         |   
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

-CLQMKEWFDYRN-----------------HVCIVSEKLGPSLYDFLKKNS--YRP------------------------FSIEHVRDIGWQLLNSVA--
 .......| ..|                 |...| | .. .||...|.|.  |..                        |.| |.| . .|.|....  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

YLHELS--LIHTDLKPENILLVSSAYV-------KTLDYKVAHFVRSFLVLLTLFPLQSARPDKHLTRTPTSAE----------IRLIDFGSATFENQH-
|.|      ||.||||||||. .   .       .                                      |          ....|||.|.....| 
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKS--------------------------------------EDWNPCQKNGRLKICDFGLARWYHPHS

-----------------------HSSIVSTRQYRAPEIILGLG----------WSYACDLWSVGCILVELFSG--------DPLFQTHEN----------
                       ... |.|| ||||||.|| .          .....| ||||||. |.. |        .|||..| .          
DHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKS

-LEHLAMMERILGPISRRIIDN------VDRKAQKYFKNGRELNW----------------PDAASSLESI---RTVKRLPRLKELVQLHVE--------
 ...|... ..||... ..|..       ... .....    ...                .. |    ..      .. . .|.|.  | .        
HIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKA

-----------------------HSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
                       .  . . |||...|.|  ..|.||..||.||.|
MVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CLK_d.AA S_TKc 25-368 21 1.1e-70 242.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-368
Range on HMM: 1-231/231
Sequence Identity: 21% (78 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALIEIDVLRALRKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGP---SLYDFLKKNSYR
|... | |.|.||.|  |...| .. ||.|.|.      | .. ||..|.        .     .....|.  .|...| | ..    .|.|..||. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

P----FSIEHVRDIGWQLLNSVAYLHELSLIHTDLKPENILLVSSAYVKTLDYKVAHFVRSFLVLLTLFPLQSARPDKHLTRTPTSAEIRLIDFGSATFE
.    |.  |.| . .|... ..|.|..  || ||||||||| .                                           .| ..|||.|.. 
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------------------------------------HIKICDFGLARQL

NQHHSSIVSTRQYRAPEIILGLGWSY-ACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPISRRIIDNVDRKAQKYFKNGRELNWPDAASSLES
    .... |. |.|||..   |... .|| ||.|||| |...| |.|.     .. .|...|.                                    
----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG------------------------------------

IRTVKRLPRLKELVQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALR-------HPFF
                      ... |.....|..  ..|.|| |||.       ||.|
---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CLK_d.AA Pkinase 25-368 20 1e-69 242.69 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-368
Range on HMM: 1-293/293
Sequence Identity: 20% (78 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALI------EIDVLRALRKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGP-----SLYD
|....| |.|.||.| .| ...... ||||.|. . . ..  ..      || ... | .|.       .....|| ...|...| | ..      .|.|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-NHPN-----IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD

FLK---KNSYRPFSIEHVRDIGWQLLNSVAYLHELSLIHTDLKPENILLVSSAYVKTLDYKVAHFVRSFLVLLTLFPLQSARPDKHLTRTPTSAEIRLID
...   ....  || ...... .|.|  ..|.|. . || ||||||||...  ....                                      ....|
YISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-------------------------------------CVKICD

FGSA----TFENQHHSSIVSTRQYRAPEIIL-GLGWSYACDLWSVGCILVELFSGDPLFQTH----ENLEHLAMMERILGPISRRIIDNVDRKA-----Q
||.|    .  |.  .... |. |.|||.|. | ......| ||.|||| |...| |.|. |    . .....|..||.||. .. ... ...      .
FGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH

KYFKNGRELNWPDAASSLESIRTVKRLPRLKELVQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
 . .                           .  ..      ... |.....|..  ..|.||...| ||.|
-W-H---------------------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CLK_d.AA DYRK 25-161 43 3.6e-57 196.25 In-house 1-139 (320) Show / Hide 
Range on Protein: 25-161
Range on HMM: 1-139/320
Sequence Identity: 43% (60 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALIEIDVLRALRKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSYRPF-
|....  | |.|| |  |||.| .| ||.|.||| ...   |.|||  |. |...|.. |  |..|.. | .|||.||| | |  .||.|||.|. ..| 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

SIEHVRDIGWQLLNSVAYLHEL-SLIHTDLKPENILLVS
|...|| .. |.|..  .||.. ..|| |||||||.|..
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQ
Kinase CLK_d.AA DYRK2 25-159 40 6.6e-53 170.21 In-house 1-135 (318) Show / Hide 
Range on Protein: 25-159
Range on HMM: 1-135/318
Sequence Identity: 40% (55 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALIEIDVLRALRKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSYRPFS
| . . .| | || |..| | |....||.|.|||  .. . |..|| .| ..|..||..   |  |.. | .|||.||. | |. .||...|||..  ||
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

IEHVRDIGWQLLNSVAYLHELSLIHTDLKPENILL
 . ||  . ..|..   ||.  .|| |||||||||
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILL
Kinase CLK_d.AA HIPK 25-160 41 1e-41 128.86 In-house 1-135 (329) Show / Hide 
Range on Protein: 25-160
Range on HMM: 1-135/329
Sequence Identity: 41% (57 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALIEIDVLRALRKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSYRPFS
| |.  .| |||| |  || |  .| ||.|...| | |     ||. .|. |.. . .     . . | |. .||.|.| | |   ||||.|.| . |  
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYH-FVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLP

IEHVRDIGWQLLNSVAYLHELSLIHTDLKPENILLV
. |.| |  | |   . | ||.||| |||||||.||
LKHIRPILQQVLTALMKLKELGLIHADLKPENIMLV
Kinase CLK_d.AA DYRK 201-368 30 1.6e-40 140.98 In-house 140-320 (320) Show / Hide 
Range on Protein: 201-368
Range on HMM: 140-320/320
Sequence Identity: 30% (56 aa)

P-TSAEIRLIDFGSATFENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPISRRIIDNV-DRKAQKY
|    .| .|||||..||.|. .. .  | |||||.|||.  .|| | ||.||||.||| | |||.   . . ||..  .||.... .||.   |...|.
PRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKF

FKNGRELNWPDAASSLESIR------TVKRLPRLKELVQLHVEHS---------ASSLTDLLEGLLRYGASDRLTAKEALRHPFF
|..   . .    .. ....      |.|. | ..  . .  ...          . ..|.....| .  . |.|...||.||.|
FDC---FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQCDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase CLK_d.AA SRPK 25-172 33 1.6e-38 95.56 In-house 1-177 (554) Show / Hide 
Range on Protein: 25-172
Range on HMM: 1-177/554
Sequence Identity: 33% (59 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALIEIDVLRALRKHDKN-----------------------GKRGCLQMKEWFDYR----
| || | | | |  |  ||| .|  .||.|. .  | | |.|. ||  | ..||||.|                       ..  ..|.   |  |    
YHVIRKLGWGHFSTVWLCWDMQYDRYVAMKIVKSAPHYTETAVDEIKLLQCVRKHDPNPQWMHFLKEYYEDYKRDCKEFDPNRCHVVQLLDHFKHRGPNG

NHVCIVSEKLGPSLYDFLKKNSYRPFSIEHVRDIGWQLLNSVAYLHEL-SLIHTDLKPENILLVSS-AYVKTLDYKV
||.| | | ||..|..  |.. |.   .. |. |  |.|    |||.  . ||||.||||.||  . .|.| .....
NHYCMVFEVLGHNLLKWIKHYNYQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENVLLCVNQDYIKRMAAEW
Kinase CLK_d.AA DYRK1 25-160 39 2.4e-36 124.87 In-house 1-138 (321) Show / Hide 
Range on Protein: 25-160
Range on HMM: 1-138/321
Sequence Identity: 39% (55 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALIEIDVLRALRKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSYRPFS
|...| .| | || |   .|.. ||.||.|.|.|   . . |.||| .|  . ||||. |   ...|. | .|||.|.| | |   ||| |.  ..|  |
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

IEHVRDIGWQLLNSVAYLH--ELSLIHTDLKPENILLV
.  .| .  |.. .. ..   ||..|| |||||||||.
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLC
Kinase CLK_d.AA YAK 25-159 41 3.4e-33 109.83 In-house 1-139 (347) Show / Hide 
Range on Protein: 25-159
Range on HMM: 1-139/347
Sequence Identity: 41% (57 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALIEIDVLRAL-RKHDKNGKR---GCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSY
|.|    | |||| |  |      | .||||| | . |   |  || .|| |  .|| |.|      | |   | ..|| |.| | |  .||..|| | .
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

RPFSIEHVRDIGWQLLNSVAYLHELSLIHTDLKPENILL
. ||.. .|    | | .   | .  .|| |||||||.|
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIML
Kinase CLK_d.AA DYRK2 199-368 26 1.9e-30 96.0 In-house 136-318 (318) Show / Hide 
Range on Protein: 199-368
Range on HMM: 136-318/318
Sequence Identity: 26% (49 aa)

RTPTSAEIRLIDFGSATFENQ-HHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPISRRIIDNV----DR
. ..   | .||||| .||.| .    . .| |||||.|||.  . | |.|| |||..||..| |||      . .|.|  .||  .. ..|.      .
KQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCF

KAQKYFK-------NGRELNWPDAASSLESIRT----VKRLPRLKELVQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
... .|.       .      .|    .. ...     .| |  |....   .    ...| .   .   .| |.|...||.||..
RRKYFFNSHCFEWYC---TFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGCEDENFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase CLK_d.AA PRP4 25-158 33 6.6e-25 88.13 In-house 1-138 (320) Show / Hide 
Range on Protein: 25-158
Range on HMM: 1-138/320
Sequence Identity: 33% (47 aa)

YKVISKMGEGTFGRVLECW-DRKYQEFVAVKVIRNVPKYREAALIEIDVLRALRKH--DKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSY-
|.|... |.| |. |  |    . .| ||.|.||| .  .   | |. .|. |     ||| |  |..|.. | .|.| |.| | .  .| . |||  | 
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKK--YG

--RPFSIEHVRDIGWQLLNSVAYLHELSLIHTDLKPENIL
    .... ||    ||.     |  .  .| |.|| |||
KDVGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNIL
Kinase CLK_d.AA DyrkP 192-283 42 9.7e-24 74.47 In-house 133-224 (323) Show / Hide 
Range on Protein: 192-283
Range on HMM: 133-224/323
Sequence Identity: 42% (39 aa)

RPDKHLTRTPTSAEIRLIDFGSATFENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPI
.|.  | .    .....|||||. |   | || |  | |||||.|.|  . |  |.||.|||| ||. |  |||  .    || .  |.||.
KPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQNDNIQGLLARVIGIIGPF
Kinase CLK_d.AA DYRK1 192-307 35 2.6e-21 71.23 In-house 131-245 (321) Show / Hide 
Range on Protein: 192-307
Range on HMM: 131-245/321
Sequence Identity: 35% (41 aa)

RPDKHLTRTPTSAEIRLIDFGSATFENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPISRRIIDNV
.|.  | . |  . |..|||||.   .|     .  | ||.||..||. .. | |.||.||||||.  |.|||   . .. .  .  .||   ...||  
KPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQA

DRKAQKYFKNGRELNW
  ||.|||.   .  |
P-KAHKYFEKDPDNTW
Kinase CLK_d.AA DyrkP 25-161 31 1.6e-19 60.37 In-house 1-141 (323) Show / Hide 
Range on Protein: 25-161
Range on HMM: 1-141/323
Sequence Identity: 31% (44 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALIEIDVLRALRKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKN----SY
|...  .|   | . . | |..    . .|.| |   | . .. || .|| .        .  |.. ..|  . |. |. | |   ||.| | |      
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQ

RPFSIEHVRDIGWQLLNSVAYLHELSLIHTDLKPENILLVS
| | .  .  |  |.| .. |.| | ||| ||||||||. |
RYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKS
Kinase CLK_d.AA SRPK 227-268 50 7.2e-18 41.12 In-house 415-456 (554) Show / Hide 
Range on Protein: 227-268
Range on HMM: 415-456/554
Sequence Identity: 50% (21 aa)

TRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHE
|||||.|| |.| |...  | ||. | . ||  || || .|.
TRQYRSPEVIIGAGYNTPADIWSTACMAFELATGDYLFEPHS
Kinase CLK_d.AA YAK 201-264 43 4e-17 54.35 In-house 142-205 (347) Show / Hide 
Range on Protein: 201-264
Range on HMM: 142-205/347
Sequence Identity: 43% (28 aa)

PTSAEIRLIDFGSATFENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLF
| . ||..|||||.  | .     .  | ||.||||..   . . | || |||..||| | |.|
PNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFLGLPIF
Kinase CLK_d.AA PRP4 206-264 49 1.5e-12 42.34 In-house 146-205 (320) Show / Hide 
Range on Protein: 206-264
Range on HMM: 146-205/320
Sequence Identity: 49% (30 aa)

IRLIDFGSATF--ENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLF
. ..|||||    ||      || | |||||||.|    |. |.||||| | ||. |  .|
LKMCDFGSASHIHENEITPYLVS-RFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMF
Kinase CLK_d.AA HIPK 206-264 46 8.1e-12 33.0 In-house 144-203 (329) Show / Hide 
Range on Protein: 206-264
Range on HMM: 144-203/329
Sequence Identity: 46% (28 aa)

IRLIDFGSATFENQH-HSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLF
.. ||||||    .   .  .  | ||||||||||    . | || ||.. ||| | ||.
VKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLY
Kinase CLK_d.AA TyrKc 25-368 16 2.6e-09 -72.14 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-368
Range on HMM: 1-280/280
Sequence Identity: 16% (63 aa)

YKVISKMGEGTFGRVLECWDRKYQEFVAVKVIRNVPKYREAALIEIDVLRAL-RKHDK--NGKRGCLQMKEWFDYRNHVCIVSE--KLGPSLYDFLKKNS
 . . | ||| ||.| ..  .   . ||||....    ||. . |. ... |  .|.   .    |.| .. | |   ..|| |  ..| .| |.|.|. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG-DLKDYLRKHR

YRPFSIEHVRDIGWQLLNSVAYLHELSLIHTDLKPENILLVSSAYVKTLDYKVAHFVRSFLVLLTLFPLQSARPDKHLTRTPTSAEIRLIDFGSATFENQ
 . .. ..  .. ||  .  .|||.  .|| ||   |.|. .                                            ..  ||| . .   
PK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------------------------------------TVKISDFGLSRDIYD

H------HSSIVSTR--QYR--------APEIILGLGWSYACDLWSVGCILVELFS-------G-----DPLFQTHENLEHLAMMERILG--PISRRIID
.      .. ....   . .        ||| |     . . | || |  . |.|.       |      . .. .|....  .|..     |.|     
DDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----

NVDRKAQKYFKNGRELNWPDAASSLESIRTVKRLPRLKELVQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
                                              .  . . .. .   .. ..|| | .|   | .|
--------------------------------------------FVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CLK_d.AA PRP4 341-368 42 1.7e-05 16.15 In-house 293-320 (320) Show / Hide 
Range on Protein: 341-368
Range on HMM: 293-320/320
Sequence Identity: 42% (12 aa)

LTDLLEGLLRYGASDRLTAKEALRHPFF
. |||...|    . | |  |||.|||.
FKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase CLK_d.AA SRPK 354-368 53 0.0001 6.46 In-house 540-554 (554) Show / Hide 
Range on Protein: 354-368
Range on HMM: 540-554/554
Sequence Identity: 53% (8 aa)

SDRLTAKEALRHPFF
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EKRATAKECLQHPWL
Kinase CLK_d.AA DYRK1 333-368 33 0.000161 11.23 In-house 286-321 (321) Show / Hide 
Range on Protein: 333-368
Range on HMM: 286-321/321
Sequence Identity: 33% (12 aa)

HVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
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HSVEDYLKFKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase CLK_d.AA DyrkP 343-368 46 0.000228 9.54 In-house 298-323 (323) Show / Hide 
Range on Protein: 343-368
Range on HMM: 298-323/323
Sequence Identity: 46% (12 aa)

DLLEGLLRYGASDRLTAKEALRHPFF
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DFVRQCLQIDFTRRPTAKEALQHPWF
Kinase CLK_d.AA YAK 341-368 28 0.000344 9.7 In-house 320-347 (347) Show / Hide 
Range on Protein: 341-368
Range on HMM: 320-347/347
Sequence Identity: 28% (8 aa)

LTDLLEGLLRYGASDRLTAKEALRHPFF
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FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase CLK_d.AA HIPK 340-368 34 0.004099 5.1 In-house 301-329 (329) Show / Hide 
Range on Protein: 340-368
Range on HMM: 301-329/329
Sequence Identity: 34% (10 aa)

SLTDLLEGLLRYGASDRLTAKEALRHPFF
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EFVHVLKKMCTWDAHKRITPCEALNHPFV