Gene SCY1 (S.moellendorffii)

SCY1

Species: S.moellendorffii
Alias: SCY1
External Links:
Annotation:

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
SCY1.AA Protein None 866 None Fasta, JSON
SCY1.NA RNA None 2601 None Fasta, JSON
SCY1.kin_dom Protein Kinase Domain None 233 None Fasta, JSON

Protein domain

Protein domains of SCY1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SCY1.AA SCY1 54-343 24 1.9e-48 165.84 In-house 1-337 (337) Show / Hide 
Range on Protein: 54-343
Range on HMM: 1-337/337
Sequence Identity: 24% (87 aa)

WKLYSGRPRNKAEHAHNPEVCVWVLDKKLLSETRQRIGITKAAEDAFL----EVVRADAGQMLKLRHPGVLRVVQALDESKTAMAMVTEPIFASVANVLG
||...|. .  ..     |. |.| |||.         |.|.. |..     |.... | .. .|||| .|...  | |||. |. .||.||.. .|||.
WKIHNGTKKYTGQ-----ECSVFVFDKKN---------IEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLK

NLEN------------------VSKTPKELRGLELGLLEIKHGLLQLTETLSFLHNNAQLVHRAISPESVFITSTGSWKFGG---------FGFAATVEQ
...|                   .. | .     |  ||...|..|... |||||| . .||. |.|||.|.. .|.|| ||         ..| . ...
KWDNKKSCQTQKTQDVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQN

TAAEAGAGASFLYPEYD---------VDEVVMPLQPPLNYTAPELTRSN------------GNPGSCSDIFSLGCLIYHLL-SREPLVLCKNN-LRAYKA
   . . .. . . |.|            .  |.||.....|||   ..                  ||.|||||||. ..   .|.  |..| .  .. 
GNPQMPWFPCQEWREMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHR

KVQYLASASF---SKIPPELVHD----LKRMLSPAELSRPTASEFTGSPFF
.. .. ..|    ..||.||        ...|..   .||....|. ...|
YMEQWNAMSHCWWDHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
S_TKc SCY1.AA S_TKc 39-343 16 6.4e-13 12.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 39-343
Range on HMM: 1-231/231
Sequence Identity: 16% (53 aa)

YELVEQIGSGGPALAWKLYSGRPRNKAEHAHNPEVCVWVLDKKLLSETRQRIGITKAAEDAFLEVVRADAGQMLKLRHPGVLRVVQALDESKTAMAMVTE
||....||.|. .  .| .  .         . .| . ...                      | .|     . | .|| . .   . ..  . . ||.|
YEILRKIGKGAFGKVYKCRHKK--------TGRIVAIKIIK----------------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVME

PIFASVANVLGNLENVSKTPKELRG-LELGLLEIKHGLLQLTETLSFLHNNAQLVHRAISPESVFITSTGSWKFGGFGFAATVEQTAAEAGAGASFLYPE
     . . ||.|  . |  .  ..   .   .... . |. . | ..|.. . .|| . || .....    | . ||.|. .                 
Y----CDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----------------

YDVDEVVMPLQPPLNYTAPELTRSNGNPGS-CSDIFSLGCLIYHLLSREPLVLCKNNLRAYKAKVQYLASASFSKIPPELVHDLKRMLSPAELSRPTASE
       . .   ..| |||.       |   .|. |.||..| .|...|.    .  . .|  .           .||. . ....|      |||| |
-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-E

FTG-------SPFF
           |.|
ALQDEWDIKCHPWF
Kinase SCY1.AA Ciliate-E2-Unclassified 177-343 19 1.6e-11 36.27 In-house 151-352 (352) Show / Hide 
Range on Protein: 177-343
Range on HMM: 151-352/352
Sequence Identity: 19% (41 aa)

QLTETLSFLHNNAQLVHRAISPESVFITSTG---SWKFGGFGFAA---------TVEQTAAEAGAGASFLYPEYDVDEVVMPLQPPLNYTAPELTRSNGN
|. . |..|| .   .|| | || ..... |     |  .||..          |  |      .  ......   . .  |   |  |||||. .....
QILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQ------QKMQIWKQQMMWTFCGTPNYMP-QYTAPEVLQGQNY

PGS---CSDIFSLGCLIYHLLSREPLVLCKN-------------------NLRAYKAKVQYLASASF----SKIPPELVHDLK----RMLSPAELSRPTA
 .|   ..||.|||...| .|  ..   ..|                    ..  |.| ..  ....     ...||  . ..    .||     .|.|.
DHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITF

SEFTGSPFF
..    |.|
EQILNHPWF
Kinase SCY1.AA Ciliate-E2 177-343 17 8.6e-10 29.78 In-house 153-365 (365) Show / Hide 
Range on Protein: 177-343
Range on HMM: 153-365/365
Sequence Identity: 17% (39 aa)

QLTE---------------TLSFLHNNAQLVHRAISPESVFITSTGSWKFGGFGFA--ATVEQTAAEAGAGASFLYPEYDVDEVVMPLQP----------
|...                | .||..   .|| | || ...      |   ||..  .. ..         . .|..  .|. ..|             
QILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFN

----PLNYTAPELTRSNGN--------PGSCSDIFSLGCLIYHLLSREPLVLCKNNLRAYKA-KVQYLASA-------------SFSKIPPELVHDLKR-
     ..| |||  .. ..         .  .||.|||...| .|. .|       ..  |  |...                 |. |...|  . .|. 
TICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF

---MLSPAELSRPT-ASEFTGSPFF
   ||   .  |.| ...    |.|
GKRMLQKDPEKRITGWEQILNHPWF
Kinase SCY1.AA Pkinase 251-343 18 7.6e-07 25.28 Pfam 175-293 (293) Show / Hide 
Range on Protein: 251-343
Range on HMM: 175-293/293
Sequence Identity: 18% (22 aa)

LNYTAPELTRSNGNPGSCSDIFSLGCLIYHLLSREPLVLCK------NNLRAYKAKVQYLASASFSKI--------------------PPELVHDLKRML
..| |||. |..   |. .|..|.||..| .|...|.   .      . .  .. . .   . ....                     ..|. . .|..|
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

SPAELSRPTASEFTGSPFF
 .   .|||| .   .|.|
CKDPKKRPTAEQILQHPWF
Kinase SCY1.AA NKF4 175-206 28 3e-06 15.47 In-house 142-172 (336) Show / Hide 
Range on Protein: 175-206
Range on HMM: 142-172/336
Sequence Identity: 28% (9 aa)

LLQLTETLSFLHNNAQLVHRAISPESVFITST
..||.  . .|| | . .||.  | .. |. .
MMQLAQAMAHLHKN-HIIHRDLKPYNIIIVEG
Kinase SCY1.AA STE 175-343 17 2.4e-05 14.98 In-house 157-359 (359) Show / Hide 
Range on Protein: 175-343
Range on HMM: 157-359/359
Sequence Identity: 17% (39 aa)

LLQLTET-LSFLHNNAQLVHRAISPESVFITSTGSWKFGGFGFAATVEQTAAEAGAGA--------SFL-YPEYDVDEVVMPLQPPLNYTAPELTRSNGN
. |. .  |..||..   .|| | |  ...      |   ||... .... |.    .        .       .|            . |||  . ||.
CRQILKGLLYYLHSHH-IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP---------WMAPEVIQQNGQ

PGS------CSDIFSLGCLIYHLLSREPLVLCKNNLRAYKAKVQYLASA-----------SFSKIP-----------------------PELVHDLKRML
. .       .|| ||||.| ...  .|     ...||. .. .  ...              ..|                       ||. . ... |
G-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCL

SPAELSRPTASEFTG--SPFF
      |||||.      ||.
QKDPNKRPTASQLLKSEHPFI
Kinase SCY1.AA CDKL 177-217 38 2.7e-05 14.08 In-house 106-146 (286) Show / Hide 
Range on Protein: 177-217
Range on HMM: 106-146/286
Sequence Identity: 38% (16 aa)

QLTETLSFLHNNAQLVHRAISPESVFIT-STGSWKFGGFGFA
|. . ..|.|..   .|| | ||  .|| . |  | ..||||
QILKAINFCHKH-NCIHRDIKPENILITPKNGQVKLCDFGFA
Kinase SCY1.AA PLK1 252-343 30 4e-05 12.51 In-house 164-253 (253) Show / Hide 
Range on Protein: 252-343
Range on HMM: 164-253/253
Sequence Identity: 30% (29 aa)

NYTAPELTRSNGNPGSCSDIFSLGCLIYHLLSREPLVLCKNNLRAYK--AKVQYLASASFSKIPPELVHDLKRMLSPAELSRPTASEFTGSPFF
|| |||.    |      ||.|.||..| ||  .|    |     |.   | .|    . |.   .|.   ..|| |   .|||...     ||
NYIAPEVLNKKGHSFEV-DIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHISQPAAQLI---RKMLDPDPTRRPTIEQVLNDEFF
Kinase SCY1.AA WEE 253-287 38 5.3e-05 12.8 In-house 199-235 (297) Show / Hide 
Range on Protein: 253-287
Range on HMM: 199-235/297
Sequence Identity: 38% (15 aa)

YTAPELTRSNG--NPGSC--SDIFSLGCLIYHLLSREPL
| |||.   .|  ...    .||||||. ||.| ....|
YMAPEI--LQGYYHYTHLYKADIFSLGITIYELACNMDL
Kinase SCY1.AA WEE 170-221 22 0.000327 10.11 In-house 112-183 (297) Show / Hide 
Range on Protein: 170-221
Range on HMM: 112-183/297
Sequence Identity: 22% (16 aa)

EIKHGLLQLTETLSFLHNNAQLVHRAISPESVFITSTG--------------------SWKFGGFGFAATVE
.|.. |... ..|...|.|  .||  | || .||.. .                      | | || . ...
MIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVTDMN
Kinase SCY1.AA IRE 270-283 50 0.000328 10.02 In-house 214-227 (292) Show / Hide 
Range on Protein: 270-283
Range on HMM: 214-227/292
Sequence Identity: 50% (7 aa)

DIFSLGCLIYHLLS
||||.|| .| ...
DIFSMGCVFYYVMT
Kinase SCY1.AA Dicty3 252-278 42 0.000333 9.56 In-house 260-287 (351) Show / Hide 
Range on Protein: 252-278
Range on HMM: 260-287/351
Sequence Identity: 42% (12 aa)

NYTAPELTRSNGN-PGSCSDIFSLGCLI
.| |||  . |.   .. |||.||||..
HYMAPEIKLNNQCCACRKSDIWSLGCTV
Kinase SCY1.AA Dicty3 170-199 33 0.000577 8.76 In-house 112-141 (351) Show / Hide 
Range on Protein: 170-199
Range on HMM: 112-141/351
Sequence Identity: 33% (10 aa)

EIKHGLLQLTETLSFLHNNAQLVHRAISPE
||.  . .|..||...|.| ...|| | ..
EISKIICDLVKTLNYIHKNCHIIHRDIKCD
Kinase SCY1.AA TyrKc 39-343 14 0.000621 -159.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 39-343
Range on HMM: 1-280/280
Sequence Identity: 14% (48 aa)

YELVEQIGSG-------GPALAWKLYSGRPRNKAEHAHNPEVCVWVLDKKLLSETRQRIGITKAAEDAFLEVVRADAGQMLKL--RHPGVLRVVQALDES
 .| ...|.|       | .                       . |  |.| ...              .|  .  |  | ||  .|| ..| . .  ..
ITLGKKLGEGAFGEVYKGTWK----------------------IQVAVKMLKEDA--------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQ

K------TAMAMVTEPIFASVANVLGNLENVSKTPKELRGLELGLLEIKHGLLQLTETLSFLHNNAQLVHRAISPESVFITSTGSWKFGGFGFAATVEQT
.        . .|.|  ...  . .  | .  ..        | . .  .  .|  .  ..|| . ...|| .    . ... .  | . || .  ..  
GRNFMYIEPLMIVME--YMPHGDLKDYLRKHRPK--------LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDD

-AAEAGAGASFLYPEYDVDEVVM----PLQ--PPLNYTAPELTRSNGNPGSCSDIFSLGCLIYHLLSREPLVLC------KNNLRAYKAKVQYLASASFS
 ..               |  ..          |.  .|||     |   . ||..| | ... ....            ..| ....   |        
DQQG-----------ESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPP

K--------IPPELVHDLKRMLSPAELSRPTASEFTGSPFF
          |.|.    |.       .||| ||     .|
NDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase SCY1.AA IRE 321-343 34 0.007894 5.15 In-house 270-292 (292) Show / Hide 
Range on Protein: 321-343
Range on HMM: 270-292/292
Sequence Identity: 34% (8 aa)

KRMLSPAELSRPTASEFTGSPFF
. |... ...|||..|    |||
HQMIHHDPQKRPTIKECLNHPFF
Kinase SCY1.AA PLK1 170-222 30 0.016212 3.79 In-house 100-151 (253) Show / Hide 
Range on Protein: 170-222
Range on HMM: 100-151/253
Sequence Identity: 30% (16 aa)

EIKHGLLQLTETLSFLHNNAQLVHRAISPESVFITSTGSWKFGGFGFAATVEQ
| .. . |. |   .|||| ...|| .    .|.      | | || | ..|.
ECRYYMYQIVEGCQYLHNN-KIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEY
Kinase SCY1.AA Ciliate-E2-Unclassified 39-49 54 0.040855 3.16 In-house 1-11 (352) Show / Hide 
Range on Protein: 39-49
Range on HMM: 1-11/352
Sequence Identity: 54% (6 aa)

YELVEQIGSGG
|....|||.||
YKIIKQIGQGG
Kinase SCY1.AA Ciliate-E2 39-49 36 0.067787 2.27 In-house 1-11 (365) Show / Hide 
Range on Protein: 39-49
Range on HMM: 1-11/365
Sequence Identity: 36% (4 aa)

YELVEQIGSGG
|.....||.|.
YKFIKKIGQGN
Kinase SCY1.AA CDKL 331-343 30 0.133961 1.24 In-house 274-286 (286) Show / Hide 
Range on Protein: 331-343
Range on HMM: 274-286/286
Sequence Identity: 30% (4 aa)

RPTASEFTGSPFF
|.|..... .|.|
RMTCEQLMHHPYF
Kinase SCY1.AA STE 39-49 45 0.261637 0.53 In-house 1-11 (359) Show / Hide 
Range on Protein: 39-49
Range on HMM: 1-11/359
Sequence Identity: 45% (5 aa)

YELVEQIGSGG
.|..|.||.|.
WEGIEKIGKGA
Kinase SCY1.AA Pkinase 39-49 45 2.488763 2.25 Pfam 1-11 (293) Show / Hide 
Range on Protein: 39-49
Range on HMM: 1-11/293
Sequence Identity: 45% (5 aa)

YELVEQIGSGG
|.....||||.
YHIGRKIGSGS