Gene ULK-p1 (S.moellendorffii)
ULK-p1
Species: S.moellendorffii
Alias: ULK-p1
External Links:
Annotation:
Sequence
Protein domains of ULK-p1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | ULK-p1.AA | Fused | 6-256 | 60 | 5.5e-163 | 547.75 | In-house | 1-251 (251) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-251/251 Sequence Identity: 60% (153 aa) YHVIELVGEGSFGKVYKGRRKFTGQTVAMKFILKHGKSDKDIENLRQEIEILRQLKHENIIEMLDAFESPQEFCVVTEFAQAKLFEILEDDKCLPEAQVQ ||| |.||.|||| |||.||| . ||.||| | | ||| .|||.|.|| |...| .||.|.| ||. .| |||..| |. .||.| .|| ||. YHVSEMVGQGSFGCVYKARRKYDSKVVAIKFIPKRGRSDKELKNLRRECEIMRRMHHPHIIHMIDSFETDKEVVVVTDYAEMELHQYLEYDGKMPEEQVR AIAKQLVRALHYLHSHRIIHRDMKPQNILIGAGGIVKLCDFGFARAMSCNTMVLRSIKGTPLYMAPELVREQPYNHTADLWSLGVILYELYVGQPPFYTN .|| .|| || ||||||| |||||||||| . .. .|||||||||.|| ||.|| |||||||||||||| |||| |.||.|||| ||||| ||||||..| RIACHLVSALYYLHSHRILHRDMKPQNILLDKNMHIKLCDFGFARNMSINTHVLTSIKGTPLYMAPELVEEQPYDHHADMWSLGCILYELMVGQPPFCAN SVYTLIRHIVKDPVKYPDTISSNFKSFLKGLLNKVSESRLTWPALLDHPFV |.. |.. |..|.||.| ||.| ...|| ||| | |..||.|| |||| SIFHLVSMIKHDDVKWPSTITSCCRNFLQGLLTKDPRHRISWPQLLCHPFV |
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Kinase | ULK-p1.AA | Pkinase | 6-256 | 33 | 4.3e-101 | 346.95 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-293/293 Sequence Identity: 33% (98 aa) YHVIELVGEGSFGKVYKGRRKFTGQTVAMKFILKHGKSD-KDIENLR-QEIEILRQLKHENIIEMLDAFESPQEFCVVTEFAQA-----KLFEILE--DD ||... .|.||||.|||...| ||..||.| | |..... ||....| .||.|.. |.|.||....|.||.... ..|.|... ||.... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KCL--PEAQVQAIAKQLVRALHYLHSHRIIHRDMKPQNILIGAGGIV----KLCDFGFARAM-SCNTMVLRSIKGTPLYMAPELVR-EQPYNHTADLWSL .|. .| ... ...|..|.| |.||..|||||.||.|||| | . |.||||.|. . | . .. ||| |||||..| |.| . .| ||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVILYELYVGQPPFYTN------SVYTLIRHIVKDPVKYPDTIS---------------------SNFKSFLKGLLNKVSESRLTWPALLDHPFV |.||||.. |.|||. . . .|. | . |.... . ...|.|.|..|.| ..|.|.. .| ||.. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | ULK-p1.AA | AGC | 6-256 | 22 | 9.40000000001e-101 | 260.61 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-395/395 Sequence Identity: 22% (90 aa) YHVIELVGEGSFGKVYKGRRK------FTGQTVAMKFILKHG---KSDK-DIENLRQE------------IEILRQLK----------HENIIE-MLDAF .... ..|.||||||| |.| ||. ||| . | . .| ..|. | .|| ... | .|. . .| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF ESPQE--FCVVTEFAQ----------A-KLFEILE---DDKCLPEAQVQAIAKQ-------LVRALHYLHS-HRIIHRD-MKPQNILIGAGGIVKLCDFG .... . | |... || .| . ....| ... .| . .| ||.|||| . ||||| .|| |||. . | .||.||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG FARA--MSC------------------------------------------------NTMVLRSIKG--TPLYMAPELVREQPYNHTADLWS--LGVILY .. ... .. .. | || ||||| . |....| || ||...| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY ELYVGQPPFYTNS----------VYTLIRHIV------KDPVKYP----------DTISSNFKSFLKGLLNKVSESRLT----------WPALLDHPFV |. .|.|||| .. . . | ...||.| . .|.. |...|.||.| | ||. . .||. EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | ULK-p1.AA | S_TKc | 6-256 | 33 | 9.5e-101 | 341.93 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-231/231 Sequence Identity: 33% (91 aa) YHVIELVGEGSFGKVYKGRRKFTGQTVAMKFILKHGKSDKDIENLRQEIEILRQLKHENIIEMLDAFESPQEFCVVTEFAQA---KLFEILEDDKC---- |......|.|.||||||.| | ||. ||.| | |..|.||.||.. .|.||. ..|.|.. .....|.|.. ||..... .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --LPEAQVQAIAKQLVRALHYLHSHRIIHRDMKPQNILIGAGGIVKLCDFGFARAMSCNTMVLRSIKGTPLYMAPELVREQPYNH-TADLWSLGVILYEL .|| ... ...|...|| |.|||.||||| ||.|||. .|.||||.|| . ... ||| |||||.. .|.. .| ||.|.||||. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM YVGQPPFYTNSVYTLIRHIVKDPVKYPDTISSNFKSFLKGLLNKVSESRLTWPALLD-------HPFV ..|.|||. .......|. |. .|.|....|.| | |.| .| ||.. LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | ULK-p1.AA | ULK | 6-256 | 29 | 1.1e-99 | 337.43 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-329/329 Sequence Identity: 29% (98 aa) YHVIELVGEGSFGKVYKGRRKFT----GQTVAMKFILKHGKSDKD--------IENLRQEIEILRQLK--------HENIIEMLDAFESPQE--FCVVTE |.... |.|||||||||| | | .. || | |.| .. | .. |..||.|...|| |.||....| ||.... . ..| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME FAQAK-LFEILEDDKC----------LPEAQVQAIAKQLVRALHYLHSHRIIHRDMKPQNILIGAG------------GIVKLCDFGFARAMSCN---TM . . |..... .| |.| ... . ||.. .. .||.|.|||||.||||||| | |..|..|||||. .... YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ VLRSIK------GTPLYMAPELVR----EQPYN-HTADLWSLGVILYELYVGQPPFYTNSVYTLI-----RH----------IVKDPVKYP-----DTIS .. . . ||||||||... ..||. ...|.||||.|.||. .|.||||.. .... . | | | ..| ..|| MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS SNFKSFLKGLLNKVSESRLTWPALLDHPFV ...|......| . . | .|. |..||.. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | ULK-p1.AA | ULK | 6-256 | 29 | 5.9e-96 | 325.08 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-324/324 Sequence Identity: 29% (96 aa) YHVIELVGEGSFG-KVYKGR--RKFT-GQTVAMKFILKHGKSDKDIE--------NLRQEIEILRQLK---HEN--IIEMLDAFESPQE--FCVVTEFAQ | ... |.|||| |||||| .. | .| || | | | . ..| | .|..||.|...|| |.| |....| ||.... .. ..|. . YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN AK-LFEILEDDKC---------LPEAQVQAIAKQLVRALHYLHSHRIIHRDMKPQNILIGAG------------GIVKLCDFGFARAMSCNT---MVLRS |..... .| |.| ... . ||.. .. .||.| |||||.||||||| | |..|..|||||. .|. ... . GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT IK------GTPLYMAPELVR----EQPYN-HTADLWSLGVILYELYVGQPPFYTNSVYTLI----RH----------IVKDPVKYPD-----TISSNFKS .. ||||||||... ..||. . .|.||||.|.||. |..||... .... .. | . |...|. ||...|. CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD FLKGLLNKVSESRLTWPALLDHPFV .....| . . | .|. ...||.. LIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | ULK-p1.AA | CAMK | 11-256 | 22 | 6.3e-86 | 276.76 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 11-256 Range on HMM: 1-425/425 Sequence Identity: 22% (94 aa) LVGEGSFGKVYKGRRKFTG------------QTVAMKFILKHGKS--------------------------DKDIENLRQEIEILRQ-------LKHENI |.||||||.....| |. | ||.|.| | . .|| .|.|.||||... |.|.|| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IEMLDAFES-------------------PQEFCVVT---EFAQAK-----LFEILEDDKC---------------LPEAQVQAIAKQLVRALHYLHSHRI | .....|. ..... |. |... ||. . . .| ..|.... . .|.. |.||.||| | IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI IHRDMKPQNILI-GAG----------------GIVKLCDFGFARAMSCN-----------------------TMVLRSIKGTPLYMA-PELVR------- .||| || |||. . . .|..|||||. . . . .. ||| ||| ||... VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM -------EQPYNHTADLWSLGVILYELYVGQPPFYTN-------------SVYTLIRHIVKDPVKYPDT----------------ISSN--------FKS ...|. .| ||.||||| . .| |||| . | | . | | .|. || . |. QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD FLKGLLNKVSESRLTWPALLDHPFV .....|.. | |.| |.||.. LIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | ULK-p1.AA | CAMKL | 6-256 | 28 | 5.9e-78 | 248.34 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-297/297 Sequence Identity: 28% (86 aa) YHVIELVGEGSFGKVYKGRR-KFTGQTVAMKFILKHGKS-DKDIEN------------LRQEIEILRQLK---HENIIEMLDAFESPQE------FCVVT | ... |.|||||| .. ..||. ||.|.| | ... | ... .|.||.|...|. |.||| ... .| |. .. |. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EFAQAK---LFEILEDDKC----LPEAQVQAIAKQLVRALHYLHSHRIIHRDMKPQNILIGAGG--IVKLCDFGFARAMS-C---NTMVLRSIKGTPLYM | .. ||. .. .. .|| . . . .|.| |..|.|||.|.||| || |||. | .|..||||. . | . |. |.| || EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APELVRE--QPYN-HTADLWSLGVILYELYVGQPPFY-------TNSVYTLIRHIVKDPVKYPD---TISSNFKSFLKGLLNKVSESRLTWPALLDHPFV |||.. .||. .| ||.||||| . .|. || .. . . ..... .||. .| .......|.. | | | .. ||.. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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Kinase | ULK-p1.AA | Ciliate-E2 | 6-256 | 25 | 4.7e-75 | 255.66 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-365/365 Sequence Identity: 25% (96 aa) YHVIELVGEGSFGKVYKGRRKFTGQ------------------TVAMKFILKHGKSDKDIENLRQEIEILR----------------QLKHENIIEMLDA | .|.. |.|.||.|||.... ... |..|.. . .. ..||.. ||| |.| ||.| |||.| .. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FE--SPQEFCVVTEFAQAK-LFEILE------------DDKCLPEAQVQAIAKQLVR---------------ALHYLHSHR-IIHRDMKPQNILIGAGGI |. . . . |.|..| . ||.... | |.. | ... | ||... ||.|||| ||||| ||.|||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- VKLCDFGFAR-AMSCNT------------------------------MVLRSIKGTPLYMAPELVREQP---------YNHTADLWSLGVILYELYVGQP .|..|||... . .| .. ..| ||| ||||| .. .. |.. .|.|||||||||. |.| IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PFYTNSVYTLIRHIVKDPVKYP------------------DTISSNFKSFLKG----LLNKVSESRLT-WPALLDHPFV || .. | . ....| . .| . | ..| .|.| | |.| | .|.||. PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | ULK-p1.AA | STE | 6-256 | 23 | 1.2e-73 | 251.04 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-359/359 Sequence Identity: 23% (85 aa) YHVIELVGEGSFGKVYKGRRK------FTGQT---------VAMKFILKHGKS---------------DKDIENLRQEIEILRQLK--HENIIEMLDAFE . || .|.|.||.|||.... ||.. .|.| . . .. ....... .||.|..... |.||.. ..... WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF -------SPQEFCVVTEFAQA-------K-LFEILEDDK-------CLPEAQVQAIAKQLVRA-LHYLHSHRIIHRDMKPQNILIGAGGIVKLCDFGFAR . .| ... |. . | ........ ..|| |. .|..|.... |.|||||.||||| ||.|||. |||||||.. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG AMSCN--------------TMVLR--SIKGTPLYMAPELVRE------QPYNHTADLWSLGVILYELYVGQPPFYT-NSVYTLIRHIVK----------- .. . ||. . .. ||| .|||| .. ..|. .| |||| . |. |.||. . . . . . . . QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC ----DPVKYPDTIS-------------------SNFKSFLKGLLNKVSESRLTWPALLD--HPFV .| . ||..| ..|| |.. |.| . | | || |||. IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | ULK-p1.AA | Ciliate-E2-Unclassified | 6-256 | 26 | 4.5e-70 | 239.1 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-352/352 Sequence Identity: 26% (92 aa) YHVIELVGEGSFGKVYKGRRKFTGQTVAMKFILKHGKSD-KDIENL---------RQEIE-------------ILRQLKHENIIEMLDAFESPQEFCVVT |..|. |.|.|||||| ..| ..| ||| . |. . . | |.| .... ||....|..|. |...|.. | .. |. YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM EFAQAK-LFEILED-----------------DKCLPEAQVQ-----AIAKQLVRALHYLHSH-RIIHRDMKPQNILIGAGG---IVKLCDFGFARAMSCN |... . |...... .|...| |.. ...|.. .| |||. ||||| ||.|||. .| .|..|||... | EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN ---------------TMVLRSIKGTPLYM----APELVREQPYNHT----ADLWSLGVILYELYVGQPPFYTNSVYT----------------LIRHIVK . . .. ||| || |||. ..| |.|. .| |||||||||. |..||| |. . |.. | . NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ DPVKYP--------DTISSNFKSFLK----GLLNKVSESRLTWPALLDHPFV ....| ...| . | |.. .|.| ..|.|.. .| ||. KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | ULK-p1.AA | RSK | 9-256 | 28 | 2.3e-69 | 236.73 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 9-256 Range on HMM: 1-278/278 Sequence Identity: 28% (80 aa) IELVGEGSFGKVYKGRRK---FTGQTVAMKFILK--HGKSDKDIENLRQEIEILRQLK-HENIIEMLDAFESPQEFCVVTEFAQ-AKLFEILEDDKC--- ... |.|..|||. |.. ||| ||| . | ...||.. ..|..|| . | .|.. .||. .... ..|. ||. |. |. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LPEAQVQAIAKQLVRALHYLHSHRIIHRDMKPQNILIGA---GGIVKLCDFGFARAMSCN-TMVLRSIKGTPLYMAPELVR---EQP-YNHTADLWSLGV . | ..... ..| |. .||.. ||||| || ||| | .||.||||.. ..|. . . . .| |||||... | ... .|.||||| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV ILYELYVGQPPFYT---NSVYTLIRHIVKDP--VKYP--DTISSNFKSFLKGLLNKVSESRLT-----WPALLDHPFV ..||. .|.|||. |. ... | | .. | ...| ..|......| . . ||. ...||. LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | ULK-p1.AA | Pkinase_Tyr | 6-217 | 28 | 3.7e-31 | 106.14 | Pfam | 1-231 (270) | Show / Hide |
Range on Protein: 6-217 Range on HMM: 1-231/270 Sequence Identity: 28% (66 aa) YHVIELVGEGSFGKVYKGRRK----FTGQTVAMKFILKHGKSDKD--IENLRQEIEILRQL-KHENIIEMLDAFE---SPQEFCVVTEFAQA-KLFEILE . .. |||.||.||||. | |...|| | . |.| .... .| . .|..|..|| .|.||. .. . |.. ..|.|... | . | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR D----DKCLPEAQVQAIAKQLVRALHYLHSHRIIHRDMKPQNILIGAGGIVKLCDFGFARAM-SCNTMVLRSIKGTPL---YMAPELVREQPYNHTADLW . .. |. . .. | ... ||.|...|||| |.|.. ...|| |||| ||.. . . .|. .|..| |||| .. ... | | KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW SLGVILYELYV-GQPP-FYTNSVYTLIRHIVKD | || ..|.. |. | .. | . ....| .| SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED |
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Kinase | ULK-p1.AA | TyrKc | 6-256 | 23 | 6e-18 | 66.87 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-280/280 Sequence Identity: 23% (67 aa) YHVIELVGEGSFGKVYKGRRKFTGQTVAMKFILKHGKSDKDIENLRQEIEILRQL--KHENIIEMLDAFESP-------QEFCVVTEFAQA-KLFEILED . .. ||| ||.||||. | ..|| | . .. .| ...|..|...| .|.||. .. . .. . ..|.|.. | . | . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK DKC-LPEAQVQAIAKQLVRALHYLHSHRIIHRDMKPQNILIGAGGIVKLCDFGFARAMSCN--------TMVLRSIKGTP--L---YMAPELVREQPYNH . |. .. .. | . ||||...|||| |.|.|....|| .||| .|. . . .. ||. | |||| .. ... HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT TADLWSLGVILYELY-VGQPPFYT-----NSVYTLIRHIVKD--PVKYPD-------TISSNFKSFLKGLLNKVSESRLTWPALLDHPFV | || || ..|.. ||.| . | . .|... . . . |. . .. . | . |.| | .. | . KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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Arm | ULK-p1.AA | Arm | 397-407 | 45 | 40.914665 | 0.57 | Pfam | 31-41 (41) | Show / Hide |
Range on Protein: 397-407 Range on HMM: 31-41/41 Sequence Identity: 45% (5 aa) QALRVLWNLLG .|...|||| NACWALWNLCA |
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Arm | ULK-p1.AA | Arm | 988-1031 | 15 | 1.088247 | 5.95 | Pfam | 1-41 (41) | Show / Hide |
Range on Protein: 988-1031 Range on HMM: 1-41/41 Sequence Identity: 15% (7 aa) SRLLAIDIVKEGLLSPLLMAKMLDPSSPKDVVLDVLMTVSNLAR . ....| . ||. ..|. .. .|. ... ...||.. NPEQKQAVIQCGCVPPLV--QLLH-HPDEEVQENACWALWNLCA |
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HEAT | ULK-p1.AA | HEAT | 1045-1075 | 32 | 0.010017 | 13.3 | Pfam | 1-31 (31) | Show / Hide |
Range on Protein: 1045-1075 Range on HMM: 1-31/31 Sequence Identity: 32% (10 aa) IWDSFKTYLVHGDSNVRARCCSALGNMCRHT | . . . | . |..||. .|..||..|.| ILPHLLKCLNDPDWEVREAACWCLGQLCEHC |
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Arm | ULK-p1.AA | Arm | 1055-1073 | 42 | 0.054476 | 10.39 | Pfam | 23-41 (41) | Show / Hide |
Range on Protein: 1055-1073 Range on HMM: 23-41/41 Sequence Identity: 42% (8 aa) HGDSNVRARCCSALGNMCR |.|..|. .| ||.|.|. HPDEEVQENACWALWNLCA |
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Arm | ULK-p1.AA | Arm | 1117-1156 | 26 | 9e-07 | 26.71 | Pfam | 1-41 (41) | Show / Hide |
Range on Protein: 1117-1156 Range on HMM: 1-41/41 Sequence Identity: 26% (11 aa) NDQLYEQLRRA--IPHLTNLLLGNEEDKTKANAAGALSNLVR |.. ...... .|.| .|| ... ... ||..||.||.. NPEQKQAVIQCGCVPPLVQLLH-HPDEEVQENACWALWNLCA |
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HEAT | ULK-p1.AA | HEAT | 1087-1117 | 29 | 0.007328 | 13.77 | Pfam | 1-31 (31) | Show / Hide |
Range on Protein: 1087-1117 Range on HMM: 1-31/31 Sequence Identity: 29% (9 aa) LIKLLIDRCADPDRHTRKFACFAVGNAAYHN .. .|. . ||| . |. || ..|. . | ILPHLLKCLNDPDWEVREAACWCLGQLCEHC |
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HEAT | ULK-p1.AA | HEAT | 1127-1158 | 21 | 0.346714 | 7.97 | Pfam | 1-31 (31) | Show / Hide |
Range on Protein: 1127-1158 Range on HMM: 1-31/31 Sequence Identity: 21% (7 aa) AIPHLTNLLLGNEEDKTKANAAGALSNLVRNS .||| ..| .... ...|. .|..|.... ILPHLLKCLN-DPDWEVREAACWCLGQLCEHC |
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Arm | ULK-p1.AA | Arm | 1158-1178 | 19 | 7.288405 | 3.13 | Pfam | 1-21 (41) | Show / Hide |
Range on Protein: 1158-1178 Range on HMM: 1-21/41 Sequence Identity: 19% (4 aa) SSKLCEDIISQGAMKALIQVI ... . .| .|....|.| . NPEQKQAVIQCGCVPPLVQLL |
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Arm | ULK-p1.AA | Arm | 1212-1242 | 16 | 58.060499 | 0.05 | Pfam | 1-31 (41) | Show / Hide |
Range on Protein: 1212-1242 Range on HMM: 1-31/41 Sequence Identity: 16% (5 aa) HAPCRQYLRSLELFRVLLQLKNSTDSTIIKY .....|... . ..|.|| ...|. . .. NPEQKQAVIQCGCVPPLVQLLHHPDEEVQEN |