Gene WEE-S1_g (S.moellendorffii)

WEE-S1_g

Species: S.moellendorffii
Alias: WEE-S1_g
External Links:
Annotation:

Classification

Group: Other
Family: WEE
Subfamily: WEE-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
WEE-S1_g.AA Protein None 134 None Fasta, JSON
WEE-S1_g.NA RNA None 405 None Fasta, JSON
WEE-S1_g.kin_dom Protein Kinase Domain None 73 None Fasta, JSON

Protein domain

Protein domains of WEE-S1_g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase WEE-S1_g.AA WEE 1-97 25 1.4e-30 99.89 In-house 73-203 (297) Show / Hide 
Range on Protein: 1-97
Range on HMM: 73-203/297
Sequence Identity: 25% (33 aa)

SWFENDFLYIQMELCET-N-----LQDESLAWTF--TEKKLTEVMFQLLNALKHLHSH-SLAHLDVKPNNIYIRNR---------------------VYK
.| |.| .|||||.|.  .     .. ....|    .|...  .  .....|.|.||. .. |.|.|| ||.| ..                     ..|
AWEEDDHMYIQMEYCNGGSNLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCK

IGDFGLTSQID----GTISIKDGNSRYLCKE
|||||. . ..     . ..  |.|||. .|
IGDFGHVTDMNSNNNNPHQEQEGDSRYMAPE
Kinase WEE-S1_g.AA Ciliate-B2 12-97 32 3.4e-21 46.51 In-house 80-173 (197) Show / Hide 
Range on Protein: 12-97
Range on HMM: 80-173/197
Sequence Identity: 32% (31 aa)

MELCETNLQDESL----AW-TFTEKKLTEVMFQLLNALKHLHSHSLAHLDVKPNNIYI-RNRVYKIGDFGLTSQID--GTISIKDGNSRYLCKE
|| ||  |..|          |...||  ..|||...|  ...    |||.|| || . .|  |.  |||  | .     |.||    .|  .|
MEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPE
Kinase WEE-S1_g.AA DAPK 28-88 34 9.4e-16 39.58 In-house 100-165 (264) Show / Hide 
Range on Protein: 28-88
Range on HMM: 100-165/264
Sequence Identity: 34% (23 aa)

FTEKKLTEVMFQLLNALKHLHSHSLAHLDVKPNNIYIRNRVYKIG-----DFGLTSQIDGTISIKD
..|.  |. | | |.....||| . .||| || ||   .| .  |     ||||   |.  . ..|
LCEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRD
Kinase WEE-S1_g.AA CAMK 2-82 18 4.2e-15 44.43 In-house 106-248 (425) Show / Hide 
Range on Protein: 2-82
Range on HMM: 106-248/425
Sequence Identity: 18% (27 aa)

WFE--------------------NDFLYIQM---ELCET-NLQDESLAWT--------------------FTEKKLTEVMFQLLNALKHLHSHSLAHLDV
..|                    ....|. |   |.|.   | |. . .                     |||.    .. |.. |....|||  .|.| 
VYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDL

KPNNIYIRNR------------------VYKIGDFGLTSQIDG
|| || . ..                    || |||.  ..|.
KPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDP
Kinase WEE-S1_g.AA MOK 30-75 43 2.3e-13 37.74 In-house 99-144 (283) Show / Hide 
Range on Protein: 30-75
Range on HMM: 99-144/283
Sequence Identity: 43% (20 aa)

EKKLTEVMFQLLNALKHLHSHSLAHLDVKPNNIYIRNRVYKIGDFG
.||. . |.||. .| |.|   . | |||| || |.. . |..|||
QKKIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQDHLKLADFG
Kinase WEE-S1_g.AA ULK 27-76 34 8.7e-13 41.05 In-house 126-188 (329) Show / Hide 
Range on Protein: 27-76
Range on HMM: 126-188/329
Sequence Identity: 34% (22 aa)

TFTEKKLTEVMFQLLNALKHLHSHSLAHLDVKPNNIYIRNR-------------VYKIGDFGL
...|..  ... |.||..|.||.|   | | || || | |              |.||.|||.
RLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGF
Kinase WEE-S1_g.AA CMGC 8-76 21 1.2e-12 36.9 In-house 130-250 (513) Show / Hide 
Range on Protein: 8-76
Range on HMM: 130-250/513
Sequence Identity: 21% (26 aa)

LYIQMELCETNLQDESLA----------WTFTEKK------------LTEVM------FQLLNALK--HLHSHS--LAHLDVKPNNIYIRNRVY------
||. .|.....| .                ..| .                |      .|.|..||  ..|||     | | || || | ..        
LYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMM

---------------KIGDFGL
               ||.||||
WKSEDWNPCQKNGRLKICDFGL
Kinase WEE-S1_g.AA ULK 27-76 33 1.6e-12 40.82 In-house 122-184 (324) Show / Hide 
Range on Protein: 27-76
Range on HMM: 122-184/324
Sequence Identity: 33% (21 aa)

TFTEKKLTEVMFQLLNALKHLHSHSLAHLDVKPNNIYIRNR-------------VYKIGDFGL
...|..  ... |..|..|.||.|   | | || || | |              |.||.|||.
RLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGF
Kinase WEE-S1_g.AA Ciliate-E2 2-81 28 1.7e-12 39.23 In-house 100-207 (365) Show / Hide 
Range on Protein: 2-81
Range on HMM: 100-207/365
Sequence Identity: 28% (32 aa)

WFE---NDFLYIQMELCET-NLQD---ESLAWT---------FTEKKLTEVMFQLLN---------------ALKHLHSHS-LAHLDVKPNNIYIRNRVY
.|.   .. .|. ||.|.  .|.|   ..  .          ||||.  ..| |.|.               ||..|||     | | ||.|| .     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----I

KIGDFGLTSQID
|| ||||  ..|
KIIDFGLSKKYD
Kinase WEE-S1_g.AA CDKL 30-76 38 2.2e-12 38.64 In-house 97-145 (286) Show / Hide 
Range on Protein: 30-76
Range on HMM: 97-145/286
Sequence Identity: 38% (19 aa)

EKKLTEVMFQLLNALKHLHSHSLAHLDVKPNNIYIR--NRVYKIGDFGL
|...  .|.|.|.|....|.|   | |.|| ||.|   | . |..|||.
EHVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGF
Kinase WEE-S1_g.AA Pkinase 2-76 34 7.7e-12 42.94 Pfam 68-158 (293) Show / Hide 
Range on Protein: 2-76
Range on HMM: 68-158/293
Sequence Identity: 34% (32 aa)

WFE-NDFLYIQMELCET-----NLQ-------DESLAWTFTEKKLTEVMFQLLNALKHLHSHSLAHLDVKPNNIYIR-NRVY----KIGDFGL
||| .| .|. ||.||       |        . ..   |.|. .  .| |.| .|...||..  | |.|| || |  | .     ||.||||
WFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY--FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase WEE-S1_g.AA S_TKc 3-134 15 0.000745 -120.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 3-134
Range on HMM: 1-231/231
Sequence Identity: 15% (37 aa)

FEN--------------------------------------------------------DFLYIQMELCET---NLQDESLAWT-------FTEKKLTEV
.|                                                         |.||. ||.|..   .| |             |.|     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

MFQLLNALKHLHSHSLAHLDVKPNNIYIRNRVYKIGDFGLTSQIDGTI----------SIKDGNSR-------------YLCKEPTPRDVVGQRIPESLT
| |...||...|||   | |.|| || . . . ||.||||  |.  |.           .  | ..              ..   .| .      .. . 
MYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMF

EMTKSSSDGT-------ESKIE-------SM-------HTRV
.. . |...        .   |                |  .
KKIG-SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF