Gene FRAY_d-2 (S.moellendorffii)

FRAY_d-2

Species: S.moellendorffii
Alias: FRAY_d-2
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: FRAY

Sequence

Name Sequence Type Origin Length Description Download
FRAY_d-2.AA Protein None 359 None Fasta, JSON
FRAY_d-2.NA RNA None 1080 None Fasta, JSON
FRAY_d-2.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of FRAY_d-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase FRAY_d-2.AA FRAY 14-276 48 6.8e-135 421.58 In-house 1-277 (277) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-277/277
Sequence Identity: 48% (135 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCR-SDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLTIMRVARPYGL---
|   | || |  |.||.|.|.|| | . || |.||||    .||...| |  ..  |||||.    |.|   ||.|| |  .|||| ||.   | |    
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

----DELLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFD--CYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCSADIWSL
    || ..||.|.| ||.|.|.| .| ||||.||||||..  | . . |||||| | .    .|.   |.|| ||||||||||.. | |||  |||||.
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCV-RHTFVGTPCWMAPEVMEQVHGYDFKADIWSF

GITALELAQGHAPLSDLPPMKMVLVELSSPPPTLEPERAKV-----FSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
||||.||| | ||  ..||||  .  |  .||.|| .  .      ...|||. .  ||||. |||||| .|||| ||
GITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase FRAY_d-2.AA STE20 14-276 39 1.3e-114 387.09 In-house 1-288 (288) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-288/288
Sequence Identity: 39% (116 aa)

YRVLEEIGHGRNATVHRALCVPRGEI----VSIKSIDLEKCR---SDLDEVRREAQTLSLIDHPNVVAALALFIVG----QRLWVVMPYMAAGSCLTIMR
|  ||.||.|   .|..| ..| ||.    | || ..||||     .....  | . ..  .|||.|. .  ....    . ||.||.|...||.. ||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---VARP----YGLDELLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFD--CYNRQIA-RRTTFAGTPCWMAPEVLDPV-
   .       . ..|  .|...||.|..||||| .. ||||.||.|||....| ||| ||||.| | .       .. .| || |||.||||||.  . 
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCME

---CGYDCSADIWSLGITALELAQGHAPLSDLPPMKMVLVEL--SSPPPTLEPERA-KVFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
    |||. .|||||||||.|.| |. |..|..||.. .  .  . |||||. .   . .|..|.|||. ||||. .||||| .|||| |.
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDD-KPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase FRAY_d-2.AA YSK 14-276 42 3.8e-102 308.39 In-house 1-257 (257) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-257/257
Sequence Identity: 42% (112 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLTIMRVARPYGLDELL
.  .| || |    |  .  .  ...| || ||||.   . . . .| | ||  | |..   .. .  .  ||..| | . ||||  |.     ..||  
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

VATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDP-VCGYDCSADIWSLGITALELAQ
.|..||| ||.|||||    ||||.|| |.|.  || |||.||||.. . |    .  .| ||.||| ||||||    | .||  ||||||||||.|.| 
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITD----TQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAK

GHAPLSDLPPMKMVLVELSSPPPTLEPERAKVFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
|. |..|. ||.      ...||.|| .    .||.||.||.||| |. ..||.|  |||| | 
GEPPYCDYHPMRVMFLIPKNNPPKLEGR---SYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase FRAY_d-2.AA STE 14-276 29 2.1e-96 326.55 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-359/359
Sequence Identity: 29% (109 aa)

YRVLEEIGHGRNATVHRALCV------PRGEI---------VSIKSIDLEKCR----------------SDLDEVRREAQTLSLID--HPNVVAALALFI
.. .|.||.|   ||..|...      . ||.         . || ..||.|.                ...... .| ....  .  |||.|  .  ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG-------QRLWVVMPYMAAGSCLTIMRVARPYGLD------------ELLVATVLRECLKA-LDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSA
..       . ||..| ||..||.  |..     | .            | ..|...|..||. |.||| |. ||||.|..|||.     ||| ||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

CLFD-CYNR----------QIA-RRTTFAGTPCWMAPEVLDP-----VCGYDCSADIWSLGITALELAQGHAPLSDLPPMK-MVLVELS-----------
.| | . |            .. .|.||.||| ||||||...     . |||...||||||.|..|.| |. |..|..||. | .   .           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---SPPPTLEPERA---------------KVFSKSFKDFVACCLQKEASKRPTAGKLLK--HGFF
    |||.|...                 . .|..||||.. ||||. .||||| .|||  | |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase FRAY_d-2.AA MST 14-276 40 1.2e-79 252.86 In-house 1-254 (254) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-254/254
Sequence Identity: 40% (107 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFI--VGQRLWVVMPYMAAGSCLTIMRVARPYGLDE
. ..| .| |    |..|..   |.|| || .  .   .||.|   |  ...  . ...|   . ..    . .| || | ..|| . ||. ..   | |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN---EDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMK-ITQRTLNE

LLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCSADIWSLGITALELA
   |..|.  |. |.|||.   |||| ||||||... |  || |||||..|.|      | | |. |||.||||||.  . .||| ||||||||||.|.|
QQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDT----MAKRNTVIGTPYWMAPEVIQEI-KYDCKADIWSLGITAIEMA

QGHAPLSDLPPMKMVLVELSSPPPTL-EPERAKVFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
 |. |.||. ||       ..||||. .||.   .|  | |||. ||||. ..|.||  ||.| |.
EGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQ---WSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase FRAY_d-2.AA S_TKc 14-276 31 4.2e-79 270.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAA--GSCLTIMRVARP----Y
|..|..||.|  ..|...  .  |.|| || |.        . .||| | |.  .|||.|  .  |   ..|..|| |.    |. .....  ..    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

GLDELLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDC-SADIWSLGIT
...|  .. .... ..||.|.| || ||||.|  |||.|.   .|..|||... |           ||| ||| .||||||    ||.. ..|.||.|..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

ALELAQGHAPLSDLPPMKMVLVELSSPPPTLEPERAKVFSKSFKDFVACCLQKEASKRPTAGKLLK-------HGFF
  |.. |  | .   ...|  . .               |...|||.  ||||. .||||| ..|.       | .|
LYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FRAY_d-2.AA KHS 14-276 40 1.2e-66 223.13 In-house 1-258 (258) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-258/258
Sequence Identity: 40% (107 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLTIMRVARPYGLDELL
| .|  .| |    |..|  .  .|.. .| | .|    |.  . .|   .    |||.||    ..  ..||..| |  .||   | .|  |  | || 
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKME-PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP--LSELQ

VATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEV--LDPVCGYDCSADIWSLGITALELA
.| | || |..|.||| .| .|||.|  |||. ..| ||| |||||| .       ||.|  | ||| ||||||   .   ||.   |||..||||.|||
IAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITAT----IAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELA

QGHAPLSDLPPMKMVLVELSSP--PPTLEPERAKVFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
    |. || ||. ...   |   ||.|. .. | .|..| .||  .| |.. ||||| |||.| |.
ELQPPMFDLHPMRALFLMTKSNFQPPKLK-DKHK-WSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase FRAY_d-2.AA MSN 14-276 36 1.2e-63 208.94 In-house 1-265 (265) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-265/265
Sequence Identity: 36% (100 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLS-LIDHPNVVAALALFI------VGQRLWVVMPYMAAGSCLTIMRVARP
. . | .| |    |.. . |  |... || .|...   . .|.. |   |     | |...    ||        ..||.|| . .|||   ... .. 
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVRE--DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKG

YGLDELLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVL----DPVCGYDCSADIWS
  | |  .| . || |. | .|| |  ||||.|  |.|. .   ||| |||||| |    .| . || || ||| ||||||.    .| . ||  .|.||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQL----DRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWS

LGITALELAQGHAPLSDLPPMKMVLVELSSPPPTLEPERAKVFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
.||||.|.| |. || |. ||. ... .  |||.|    .| .|| |..|.  || |. ..||.....|||.| 
VGITAIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK---SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase FRAY_d-2.AA SLK 14-276 36 3.2e-62 208.68 In-house 1-259 (259) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-259/259
Sequence Identity: 36% (97 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLTIMRVARPYGLDELL
. .. |.| |    |..|    .. .   |.|....   .|..   | . || ..|||.|  .  . . ..||... . . |   .|| |    .| |  
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKD-EEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIM-VELEHPLTEDQ

VATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCG------YDCSADIWSLGITA
.. | .. . ||..|| .  ||||.||||||. . |.|.| |||||| .     ... .| || ||| ||||||.  .|       ||. ||||||||| 
IQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKN----KHTMQKRDTFIGTPYWMAPEVV--MCETFKDQPYDYKADIWSLGITL

LELAQGHAPLSDLPPMKMVLVELSSPPPTLEPERAKVFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
.|.||.  | ... ||...|    | ||||  |.   .||.||||.  ||.|.. .|.|. .|..| ..
IEMAQMEPPHHEMNPMRVLLKIQKSEPPTL--EQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase FRAY_d-2.AA PAKA 14-276 35 1.2e-56 194.55 In-house 1-260 (260) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-260/260
Sequence Identity: 35% (95 aa)

YRVLEEIGHGRNATVHRALCVPRGEI--VSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLT--IMRVAR-PYG
|...|.|| |   .| .|  .  ..   | || .....  .  . .  |  ..    |.|.|  .  ..|   ||||| ||..| |||  |  ...   .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGG-CLTDVITQCCNIQCN

-LDELLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCSADIWSLGITA
 .||  .| |.||||..|...| .. ||||.|  |||... | ||. |||  | |    ...  .|.|  ||| ||||||.     ||   ||||||| |
YMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQL----TQEQQKRNTMVGTPYWMAPEVIR-RKQYDEKVDIWSLGIMA

LELAQGHAPLSDLPPMK-MVLVELSSPPPTLEPERAKVFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
.|.. |  |  . || . | |.     |. ..|..   .|..|.||.. ||...  .|..| .||.| |.
IEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDK---WSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase FRAY_d-2.AA NinaC 14-276 36 1.8e-55 190.57 In-house 1-267 (267) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-267/267
Sequence Identity: 36% (102 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLD-EVRREAQTL-SLIDHPNVVAALALF-----IVGQRLWVVMPYMAAGSCLTIMR--VA
. . |.|| | .. | ...    |.|. .|  .     .|.| |.  | ..|  . ||||||    ..     ..| .|| || | . ||   . .    
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYI---HDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLK

RPYGLDELLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCS----ADI
.   ..| ..| .|.| . .|  || .  ||||||  |||  . ||||| |||||| |         || |  ||||||||||      || .    .|.
CGRRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQL----DSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDV

WSLGITALELAQGHAPLSDLPPMKMVLVELSSPPPTLEPERAKVFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
||||||| ||. |  |. |. ||..       |||||   .    .. | ||.  || |.. |||.   .|.| | 
WSLGITAIELGDGDPPFADMHPMRAMFKIPRNPPPTL--MHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase FRAY_d-2.AA Pkinase 14-276 27 3.6e-55 194.39 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRR---EAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAG----SCLTIMR--VA
|.... || |  ..| ..  .  |.|| .| |.... .|. |. .|   |.| .  ..|||.|  .  |  ......||.|.  |    .  ....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RPYGLDELLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGV----KLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCSADI
... ..|  .  .... |..|.|.| .| ||||.|  |||.|..| .    |..|||.....    .      |||.||| .|||||.    .|. ..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGITALELAQGHAPLSDL------PPMKMVLVELSSPPPTLEP-----------------ERAKVFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
||.|..  |.. |. | ..        .|.|.   .. |..  .|                 .. .  |...|||. .||.|  .|||||  .|.| .|
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase FRAY_d-2.AA Pkinase_Tyr 14-159 25 1.4e-17 60.17 Pfam 1-158 (270) Show / Hide 
Range on Protein: 14-159
Range on HMM: 1-158/270
Sequence Identity: 25% (41 aa)

YRVLEEIGHGRNATVHRALCV----PRGEIVSIKSIDLEKCRSD---LDEVRREAQTLSLI-DHPNVVAALALFI-VGQR--LWVVMPYMAAGSCLTIMR
 . ....|.|   .|... .       .  | .|..  |.. ..   ...  |||.... . .|||.|  ..  .  |.   ...||.||. |. |.  |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

VARPYGLDELLVATVLRECL---KALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVS
  |  . . | . . |  |.   |...||. .. ||||. | |.||.  . || .||| .
KHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase FRAY_d-2.AA TyrKc 14-276 21 8.1e-16 33.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLI--DHPNVVAALALFIVG-------QRLWVVMPYMAAGSCLTIMRVA
 . ....|.|   .|...      . | .|..  ..    . . .|||. .. .  .|||.|. ..  . .       . |..|| ||. |...   |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

RPYGLDELLVATVLRECL---KALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDC--------YNRQ----IAR--RTTFAGTPCWMAPEV
||     | ... |  |.   .  .||| .. ||||  | |.||.  . || .||| |  . |         | |.     ..           |||||.
RPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR-----WMAPEC

LDPVCG-YDCSADIWSLGITALELA-QGHAPLSD-----LPP---MKMVLVELSSPPPTL-EPERAKV----FSKSFKDFVACCLQKEASKRPTAGKLLK
.    | .    |.|| |..  |.   |  | ..     ...   .. |      |.|   .     .     ..   .   .| . ....|||   .  
I--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--

HGFF
| .|
HECF